ARL17B (ARF like GTPase 17B)

Gene

• Entrez ID: 100506084
• Gene name: ARF like GTPase 17B
• Gene symbol: ARL17B
• Synonyms (NCBI Gene): ARL17, ARL17A
• Chromosome: 17
• Chromosome location: 17q21.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT661250	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT661249	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT661248	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT661247	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT661246	hsa-miR-3666	HITS-CLIP	23824327
MIRT661245	hsa-miR-4295	HITS-CLIP	23824327
MIRT661244	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT661243	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT661242	hsa-miR-3655	HITS-CLIP	23824327
MIRT661241	hsa-miR-7158-5p	HITS-CLIP	23824327
MIRT661240	hsa-miR-3135b	HITS-CLIP	23824327
MIRT661239	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT661238	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT661237	hsa-miR-4284	HITS-CLIP	23824327
MIRT661236	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT661235	hsa-miR-3652	HITS-CLIP	23824327
MIRT661234	hsa-miR-4430	HITS-CLIP	23824327
MIRT661233	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT661232	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT661231	hsa-miR-578	HITS-CLIP	23824327
MIRT661250	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT661249	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT661248	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT661247	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT661246	hsa-miR-3666	HITS-CLIP	23824327
MIRT661245	hsa-miR-4295	HITS-CLIP	23824327
MIRT661244	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT661243	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT661242	hsa-miR-3655	HITS-CLIP	23824327
MIRT661241	hsa-miR-7158-5p	HITS-CLIP	23824327
MIRT661240	hsa-miR-3135b	HITS-CLIP	23824327
MIRT661239	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT661238	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT661237	hsa-miR-4284	HITS-CLIP	23824327
MIRT661236	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT661235	hsa-miR-3652	HITS-CLIP	23824327
MIRT661234	hsa-miR-4430	HITS-CLIP	23824327
MIRT661233	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT661232	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT661231	hsa-miR-578	HITS-CLIP	23824327
MIRT797646	hsa-miR-296-3p	CLIP-seq
MIRT797647	hsa-miR-3613-3p	CLIP-seq
MIRT797648	hsa-miR-4265	CLIP-seq
MIRT797649	hsa-miR-4296	CLIP-seq
MIRT797650	hsa-miR-4322	CLIP-seq
MIRT797651	hsa-miR-493	CLIP-seq
MIRT797652	hsa-miR-568	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005525	Function	GTP binding	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005794	Component	Golgi apparatus	IEA
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0006886	Process	Intracellular protein transport	IBA	21873635
GO:0016192	Process	Vesicle-mediated transport	IBA	21873635

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Alzheimer disease	Alzheimer`s Disease	rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039, rs63750973, rs63749810, rs63750643, rs193922916, rs63750306, rs63750590, rs63750526, rs63751235, rs661, rs63751037, rs63749885, rs63750231, rs63751229, rs63751272, rs63751223, rs63750391, rs63751163, rs281875357, rs63751141, rs63750082, rs121917807, rs63751399, rs63750265, rs63751144, rs63750886, rs63751068, rs121917808, rs63749891, rs63750083, rs63749824, rs63750577, rs267606983, rs63750218, rs63751287, rs63750900, rs63751475, rs63750450, rs63749805, rs63751278, rs63751106, rs63750004, rs63749806, rs63751024, rs63750248, rs63750779, rs63751139, rs63750219, rs63750298, rs63750687, rs63750851, rs1553268799, rs1561901881, rs1561905293, rs866101707, rs1566638673, rs63750009, rs1566656702, rs1566657804, rs1567885728, rs1568339995, rs1566630791, rs1555358260, rs63750964, rs1594998354, rs63751316	31473137, 25778476
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	29059683

Unknown
Disease term	Disease name	Evidence	References	Source
Asthma	Asthma			GWAS
Neuroticism	Neuroticism			GWAS
Hypertension	Hypertension			GWAS
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA
Pulmonary Fibrosis	Pulmonary Fibrosis			GWAS
Schizophrenia	Schizophrenia			GWAS
Otosclerosis	Otosclerosis			GWAS
Heart Failure	Heart Failure			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Neoplasms	Associate	30914738
Pediatric acute onset neuropsychiatric syndrome	Associate	39394562
Supranuclear Palsy Progressive	Associate	27115769