Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	1005
Gene name	Cadherin 7
Gene symbol	CDH7
Synonyms (NCBI Gene)	CDH7L1
Chromosome	18
Chromosome location	18q22.1
Summary	This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein.

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Show/Hide all (207)

miRTarBase ID	miRNA	Experiments	Reference
MIRT725598	hsa-miR-4491	HITS-CLIP	19536157
MIRT725597	hsa-miR-4657	HITS-CLIP	19536157
MIRT725596	hsa-miR-4719	HITS-CLIP	19536157
MIRT725595	hsa-miR-4253	HITS-CLIP	19536157
MIRT725594	hsa-miR-6862-5p	HITS-CLIP	19536157
MIRT725593	hsa-miR-376b-5p	HITS-CLIP	19536157
MIRT725592	hsa-miR-376c-5p	HITS-CLIP	19536157
MIRT725591	hsa-miR-3691-5p	HITS-CLIP	19536157
MIRT725590	hsa-miR-8056	HITS-CLIP	19536157
MIRT725589	hsa-miR-513b-5p	HITS-CLIP	19536157
MIRT725588	hsa-miR-4752	HITS-CLIP	19536157
MIRT497207	hsa-miR-2116-5p	HITS-CLIP	19536157
MIRT497206	hsa-miR-22-5p	HITS-CLIP	19536157
MIRT725587	hsa-miR-4795-3p	HITS-CLIP	19536157
MIRT725586	hsa-miR-4273	HITS-CLIP	19536157
MIRT725585	hsa-miR-7156-5p	HITS-CLIP	19536157
MIRT497203	hsa-miR-4677-5p	HITS-CLIP	19536157
MIRT725584	hsa-miR-578	HITS-CLIP	19536157
MIRT725583	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT676638	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT688780	hsa-miR-6089	HITS-CLIP	23313552
MIRT688779	hsa-miR-6087	HITS-CLIP	23313552
MIRT671456	hsa-miR-4767	HITS-CLIP	23313552
MIRT688778	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT688777	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT688776	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT688775	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT688774	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT688773	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT671451	hsa-miR-7977	HITS-CLIP	23313552
MIRT688772	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT688771	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT688770	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT688769	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT688768	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT688767	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT688766	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT688765	hsa-miR-3689c	HITS-CLIP	23313552
MIRT688764	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT688763	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT688762	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT688761	hsa-miR-3122	HITS-CLIP	23313552
MIRT688760	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT688759	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT688758	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT676640	hsa-miR-8485	HITS-CLIP	23824327
MIRT676639	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT676638	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT676637	hsa-miR-3918	HITS-CLIP	23824327
MIRT671460	hsa-miR-6499-5p	HITS-CLIP	23824327
MIRT676636	hsa-miR-4284	HITS-CLIP	23824327
MIRT676635	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT676634	hsa-miR-6781-5p	HITS-CLIP	23824327
MIRT676633	hsa-miR-3178	HITS-CLIP	23824327
MIRT671451	hsa-miR-7977	HITS-CLIP	23824327
MIRT671465	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT671464	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT671462	hsa-miR-5690	HITS-CLIP	23824327
MIRT671463	hsa-miR-1203	HITS-CLIP	23824327
MIRT671460	hsa-miR-6499-5p	HITS-CLIP	23824327
MIRT671461	hsa-miR-20b-3p	HITS-CLIP	23824327
MIRT671459	hsa-miR-377-5p	HITS-CLIP	23824327
MIRT671457	hsa-miR-6086	HITS-CLIP	23824327
MIRT671458	hsa-miR-6720-3p	HITS-CLIP	23824327
MIRT671456	hsa-miR-4767	HITS-CLIP	23824327
MIRT671455	hsa-miR-566	HITS-CLIP	23824327
MIRT671454	hsa-miR-1908-5p	HITS-CLIP	23824327
MIRT671453	hsa-miR-663a	HITS-CLIP	23824327
MIRT671452	hsa-miR-6787-5p	HITS-CLIP	23824327
MIRT671451	hsa-miR-7977	HITS-CLIP	23824327
MIRT497211	hsa-miR-4635	PAR-CLIP	22291592
MIRT497210	hsa-miR-9-5p	PAR-CLIP	22291592
MIRT497209	hsa-miR-6081	PAR-CLIP	22291592
MIRT497208	hsa-miR-124-5p	PAR-CLIP	22291592
MIRT497207	hsa-miR-2116-5p	PAR-CLIP	22291592
MIRT497206	hsa-miR-22-5p	PAR-CLIP	22291592
MIRT497205	hsa-miR-203a-3p	PAR-CLIP	22291592
MIRT497204	hsa-miR-6874-5p	PAR-CLIP	22291592
MIRT497203	hsa-miR-4677-5p	PAR-CLIP	22291592
MIRT444975	hsa-miR-5571-5p	PAR-CLIP	22100165
MIRT444976	hsa-miR-7845-5p	PAR-CLIP	22100165
MIRT444974	hsa-miR-3126-5p	PAR-CLIP	22100165
MIRT444973	hsa-miR-6875-5p	PAR-CLIP	22100165
MIRT444972	hsa-miR-4419a	PAR-CLIP	22100165
MIRT444971	hsa-miR-4510	PAR-CLIP	22100165
MIRT444970	hsa-miR-6127	PAR-CLIP	22100165
MIRT444969	hsa-miR-6129	PAR-CLIP	22100165
MIRT444968	hsa-miR-6130	PAR-CLIP	22100165
MIRT444967	hsa-miR-6133	PAR-CLIP	22100165
MIRT444966	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT444965	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT444964	hsa-miR-1226-5p	PAR-CLIP	22100165
MIRT444963	hsa-miR-6734-5p	PAR-CLIP	22100165
MIRT444962	hsa-miR-1273e	PAR-CLIP	22100165
MIRT444961	hsa-miR-487a-5p	PAR-CLIP	22100165
MIRT444960	hsa-miR-487b-5p	PAR-CLIP	22100165
MIRT444975	hsa-miR-5571-5p	PAR-CLIP	22100165
MIRT444976	hsa-miR-7845-5p	PAR-CLIP	22100165
MIRT444974	hsa-miR-3126-5p	PAR-CLIP	22100165
MIRT444973	hsa-miR-6875-5p	PAR-CLIP	22100165
MIRT444972	hsa-miR-4419a	PAR-CLIP	22100165
MIRT444971	hsa-miR-4510	PAR-CLIP	22100165
MIRT444970	hsa-miR-6127	PAR-CLIP	22100165
MIRT444969	hsa-miR-6129	PAR-CLIP	22100165
MIRT444968	hsa-miR-6130	PAR-CLIP	22100165
MIRT444967	hsa-miR-6133	PAR-CLIP	22100165
MIRT444966	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT444965	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT444964	hsa-miR-1226-5p	PAR-CLIP	22100165
MIRT444963	hsa-miR-6734-5p	PAR-CLIP	22100165
MIRT444962	hsa-miR-1273e	PAR-CLIP	22100165
MIRT444961	hsa-miR-487a-5p	PAR-CLIP	22100165
MIRT444960	hsa-miR-487b-5p	PAR-CLIP	22100165
MIRT676638	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT688780	hsa-miR-6089	HITS-CLIP	23313552
MIRT688779	hsa-miR-6087	HITS-CLIP	23313552
MIRT671456	hsa-miR-4767	HITS-CLIP	23313552
MIRT688778	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT688777	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT688776	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT688775	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT688774	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT688773	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT671451	hsa-miR-7977	HITS-CLIP	23313552
MIRT688772	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT688771	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT688770	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT688769	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT688768	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT688767	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT688766	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT688765	hsa-miR-3689c	HITS-CLIP	23313552
MIRT688764	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT688763	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT688762	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT688761	hsa-miR-3122	HITS-CLIP	23313552
MIRT688760	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT688759	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT688758	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT676640	hsa-miR-8485	HITS-CLIP	23824327
MIRT676639	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT676638	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT676637	hsa-miR-3918	HITS-CLIP	23824327
MIRT671460	hsa-miR-6499-5p	HITS-CLIP	23824327
MIRT676636	hsa-miR-4284	HITS-CLIP	23824327
MIRT676635	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT676634	hsa-miR-6781-5p	HITS-CLIP	23824327
MIRT676633	hsa-miR-3178	HITS-CLIP	23824327
MIRT671451	hsa-miR-7977	HITS-CLIP	23824327
MIRT671465	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT671464	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT671462	hsa-miR-5690	HITS-CLIP	23824327
MIRT671463	hsa-miR-1203	HITS-CLIP	23824327
MIRT671460	hsa-miR-6499-5p	HITS-CLIP	23824327
MIRT671461	hsa-miR-20b-3p	HITS-CLIP	23824327
MIRT671459	hsa-miR-377-5p	HITS-CLIP	23824327
MIRT671457	hsa-miR-6086	HITS-CLIP	23824327
MIRT671458	hsa-miR-6720-3p	HITS-CLIP	23824327
MIRT671456	hsa-miR-4767	HITS-CLIP	23824327
MIRT671455	hsa-miR-566	HITS-CLIP	23824327
MIRT671454	hsa-miR-1908-5p	HITS-CLIP	23824327
MIRT671453	hsa-miR-663a	HITS-CLIP	23824327
MIRT671452	hsa-miR-6787-5p	HITS-CLIP	23824327
MIRT671451	hsa-miR-7977	HITS-CLIP	23824327
MIRT497211	hsa-miR-4635	PAR-CLIP	22291592
MIRT497210	hsa-miR-9-5p	PAR-CLIP	22291592
MIRT497209	hsa-miR-6081	PAR-CLIP	22291592
MIRT497208	hsa-miR-124-5p	PAR-CLIP	22291592
MIRT497207	hsa-miR-2116-5p	PAR-CLIP	22291592
MIRT497206	hsa-miR-22-5p	PAR-CLIP	22291592
MIRT497205	hsa-miR-203a-3p	PAR-CLIP	22291592
MIRT497204	hsa-miR-6874-5p	PAR-CLIP	22291592
MIRT497203	hsa-miR-4677-5p	PAR-CLIP	22291592
MIRT444975	hsa-miR-5571-5p	PAR-CLIP	22100165
MIRT444976	hsa-miR-7845-5p	PAR-CLIP	22100165
MIRT444974	hsa-miR-3126-5p	PAR-CLIP	22100165
MIRT444973	hsa-miR-6875-5p	PAR-CLIP	22100165
MIRT444972	hsa-miR-4419a	PAR-CLIP	22100165
MIRT444971	hsa-miR-4510	PAR-CLIP	22100165
MIRT444970	hsa-miR-6127	PAR-CLIP	22100165
MIRT444969	hsa-miR-6129	PAR-CLIP	22100165
MIRT444968	hsa-miR-6130	PAR-CLIP	22100165
MIRT444967	hsa-miR-6133	PAR-CLIP	22100165
MIRT444966	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT444965	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT444964	hsa-miR-1226-5p	PAR-CLIP	22100165
MIRT444963	hsa-miR-6734-5p	PAR-CLIP	22100165
MIRT444962	hsa-miR-1273e	PAR-CLIP	22100165
MIRT444961	hsa-miR-487a-5p	PAR-CLIP	22100165
MIRT444960	hsa-miR-487b-5p	PAR-CLIP	22100165
MIRT444975	hsa-miR-5571-5p	PAR-CLIP	22100165
MIRT444976	hsa-miR-7845-5p	PAR-CLIP	22100165
MIRT444974	hsa-miR-3126-5p	PAR-CLIP	22100165
MIRT444973	hsa-miR-6875-5p	PAR-CLIP	22100165
MIRT444972	hsa-miR-4419a	PAR-CLIP	22100165
MIRT444971	hsa-miR-4510	PAR-CLIP	22100165
MIRT444970	hsa-miR-6127	PAR-CLIP	22100165
MIRT444969	hsa-miR-6129	PAR-CLIP	22100165
MIRT444968	hsa-miR-6130	PAR-CLIP	22100165
MIRT444967	hsa-miR-6133	PAR-CLIP	22100165
MIRT444966	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT444965	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT444964	hsa-miR-1226-5p	PAR-CLIP	22100165
MIRT444963	hsa-miR-6734-5p	PAR-CLIP	22100165
MIRT444962	hsa-miR-1273e	PAR-CLIP	22100165
MIRT444961	hsa-miR-487a-5p	PAR-CLIP	22100165
MIRT444960	hsa-miR-487b-5p	PAR-CLIP	22100165

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000902	Process	Cell morphogenesis	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005912	Component	Adherens junction	IBA
GO:0007043	Process	Cell-cell junction assembly	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0008013	Function	Beta-catenin binding	IBA
GO:0016020	Component	Membrane	IEA
GO:0016339	Process	Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IBA
GO:0016342	Component	Catenin complex	IBA
GO:0016477	Process	Cell migration	IBA
GO:0034332	Process	Adherens junction organization	IBA
GO:0044331	Process	Cell-cell adhesion mediated by cadherin	IBA
GO:0045296	Function	Cadherin binding	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0098609	Process	Cell-cell adhesion	IEA
GO:0098609	Process	Cell-cell adhesion	NAS	10861224

MIM	HGNC	e!Ensembl
605806	1766	ENSG00000081138

Q9ULB5

Protein name

Cadherin-7

Protein function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00028	Cadherin	52 → 144	Cadherin domain	Domain
PF00028	Cadherin	158 → 253	Cadherin domain	Domain
PF00028	Cadherin	267 → 369	Cadherin domain	Domain
PF00028	Cadherin	382 → 473	Cadherin domain	Domain
PF00028	Cadherin	486 → 583	Cadherin domain	Domain
PF01049	Cadherin_C	631 → 779	Cadherin cytoplasmic region	Family

Sequence

MKLGKVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEY
MGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTL
RAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDA
DDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNG
GLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYK
IVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSD
TTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTD
LERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAP
EFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNT
ASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYV
LPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGE
EDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADV
DPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQ
ESLYS

Sequence length

785

Interactions

View interactions

	Reactome
			Adherens junctions interactions

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs61741837	RCV005903387

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Macular Degeneration	Associate	23577725
Melanoma	Associate	19200257
Neoplasms	Associate	19200257
Rectal Neoplasms	Associate	29956755
Stomach Neoplasms	Associate	34880371

CDH7 (cadherin 7)