HOTTIP (HOXA distal transcript antisense RNA)

Gene
Gene miRNA Gene ontology Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
100316868
Gene name Gene Name - the full gene name approved by the HGNC.
HOXA distal transcript antisense RNA
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
HOTTIP
Synonyms (NCBI Gene) Gene synonyms aliases
HOXA-AS6, HOXA13-AS1, NCRNA00213
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p15.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene produces a long RNA in antisense to the HOXA gene cluster. This transcript may regulate expression of HOXA genes in cis. This gene is upregulated in tumors and is implicated in the promotion of cell proliferation. [provided by RefSeq, Dec 2017]
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Associated diseases
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT756116 hsa-miR-574-5p Luciferase reporter assay, qRT-PCR 38238652
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Associated diseases
Show/Hide all(4)
GO ID Ontology Definition Evidence Reference
GO:0000512 Process LncRNA-mediated post-transcriptional gene silencing IDA 31002141
GO:0035198 Function MiRNA binding IPI 31002141
GO:0140869 Function MiRNA inhibitor activity via base-pairing IDA 31002141
GO:2000627 Process Positive regulation of miRNA catabolic process IDA 31002141
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Associated diseases
MIM HGNC e!Ensembl
614060 37461 HGNC
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Gene ontology Other IDs Associated diseases
Show/Hide Unknown Diseases (2)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Atrial Fibrillation Atrial fibrillation N/A N/A GWAS
Hypertension Hypertension, Hypertension (confirmatory factor analysis Factor 12), High blood pressure / hypertension, Hypertension (PheCode 401), Essential hypertension (PheCode 401.1) N/A N/A GWAS
Show/Hide Text Mining Associations (44)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma of Lung Stimulate 29272003
Adenocarcinoma of Lung Associate 30685769
Anorchia Associate 31328440
Arthritis Rheumatoid Inhibit 39475402
Breast Neoplasms Associate 30024606, 34069089
Carcinogenesis Associate 31032351
Carcinoma Hepatocellular Stimulate 29930469, 32525601
Carcinoma Hepatocellular Associate 30685769, 39259658
Carcinoma Non Small Cell Lung Associate 30819158
Carcinoma Renal Cell Associate 31351427, 35529267, 36438902