ZNF729 (zinc finger protein 729)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID 100287226
Gene name Zinc finger protein 729
Gene symbol ZNF729
Synonyms (NCBI Gene)
-
Chromosome 19
Chromosome location 19p12
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all (9)
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A6NN14
Protein name Zinc finger protein 729
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 12 → 53 KRAB box Family
PF00096 zf-C2H2 264 → 286 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 292 → 314 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 320 → 342 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 376 → 398 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 404 → 426 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 432 → 454 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 460 → 482 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 488 → 510 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 516 → 538 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 544 → 566 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 572 → 594 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 600 → 622 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 628 → 650 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 656 → 678 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 684 → 706 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 712 → 734 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 740 → 762 Zinc finger, C2H2 type Domain
PF13912 zf-C2H2_6 767 → 790 Domain
PF00096 zf-C2H2 796 → 818 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 824 → 846 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 852 → 874 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 908 → 930 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 936 → 958 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 964 → 986 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 992 → 1014 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 1020 → 1042 Zinc finger, C2H2 type Domain
PF13912 zf-C2H2_6 1077 → 1098 Domain
PF00096 zf-C2H2 1104 → 1126 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 1132 → 1154 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 1160 → 1182 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 1188 → 1210 Zinc finger, C2H2 type Domain
Sequence 
MPGAPGSLEMGPLTFRDVTIEFSLEEWQCLDTVQQNLYRDVMLENYRNLVFLGMAVFKPD
LITCLKQGKEPWNMKRHEMVTKPPVMRSHFTQDLWPDQSTKDSFQEVILRTYARCGHKNL
RLRKDCKSANEGKMHKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTF
KCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKK
CGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKA
FKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQS
STLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLK
KHKIIHTGKKPYKCEECGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKA
IHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIHTG
EKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLY
KCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEE
CGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKA
FKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSF
SALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALR
KHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKV
IHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTG
KKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKHKLIHTREKLY
KCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEE
CDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKA
FSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQC
SYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECAKAF
Sequence length 1252
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (3)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
EBV-positive nodal T- and NK-cell lymphoma Likely benign ClinVar
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (1)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Thymoma Inhibit 36916520
★★★★★
★☆☆☆☆
Found in Text Mining only