Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	100271715
Gene name Gene Name - the full gene name approved by the HGNC.	Rho guanine nucleotide exchange factor 33
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ARHGEF33
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2p22.1

Show/Hide all(130)

miRTarBase ID	miRNA	Experiments	Reference
MIRT038759	hsa-miR-93-3p	CLASH	23622248
MIRT515225	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT512269	hsa-miR-6074	HITS-CLIP	21572407
MIRT512268	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707183	hsa-miR-155-3p	HITS-CLIP	21572407
MIRT707182	hsa-miR-3685	HITS-CLIP	21572407
MIRT512267	hsa-miR-1277-3p	HITS-CLIP	21572407
MIRT512266	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	20371350
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	20371350
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	21572407
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	21572407
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT512269	hsa-miR-6074	PAR-CLIP	23446348
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	23446348
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT512269	hsa-miR-6074	PAR-CLIP	23446348
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	23446348
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT515225	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT512269	hsa-miR-6074	HITS-CLIP	21572407
MIRT512268	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707183	hsa-miR-155-3p	HITS-CLIP	21572407
MIRT707182	hsa-miR-3685	HITS-CLIP	21572407
MIRT512267	hsa-miR-1277-3p	HITS-CLIP	21572407
MIRT512266	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	20371350
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	20371350
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	21572407
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	21572407
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT515225	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT512269	hsa-miR-6074	PAR-CLIP	23446348
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	23446348
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT512269	hsa-miR-6074	PAR-CLIP	23446348
MIRT512268	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT512267	hsa-miR-1277-3p	PAR-CLIP	23446348
MIRT512266	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT795782	hsa-miR-1264	CLIP-seq
MIRT795783	hsa-miR-136	CLIP-seq
MIRT795784	hsa-miR-192	CLIP-seq
MIRT795785	hsa-miR-215	CLIP-seq
MIRT795786	hsa-miR-2681	CLIP-seq
MIRT795787	hsa-miR-298	CLIP-seq
MIRT795788	hsa-miR-299-5p	CLIP-seq
MIRT795789	hsa-miR-3140-5p	CLIP-seq
MIRT795790	hsa-miR-3155	CLIP-seq
MIRT795791	hsa-miR-3155b	CLIP-seq
MIRT795792	hsa-miR-3158-5p	CLIP-seq
MIRT795793	hsa-miR-3661	CLIP-seq
MIRT795794	hsa-miR-370	CLIP-seq
MIRT795795	hsa-miR-4503	CLIP-seq
MIRT795796	hsa-miR-4680-3p	CLIP-seq
MIRT795797	hsa-miR-4719	CLIP-seq
MIRT795798	hsa-miR-484	CLIP-seq
MIRT795799	hsa-miR-5096	CLIP-seq
MIRT795800	hsa-miR-515-5p	CLIP-seq
MIRT795801	hsa-miR-631	CLIP-seq
MIRT1935039	hsa-miR-1238	CLIP-seq
MIRT1935040	hsa-miR-3117-5p	CLIP-seq
MIRT1935041	hsa-miR-4446-5p	CLIP-seq
MIRT1935042	hsa-miR-4504	CLIP-seq
MIRT1935043	hsa-miR-542-3p	CLIP-seq
MIRT1935044	hsa-miR-579	CLIP-seq
MIRT2174924	hsa-miR-1911	CLIP-seq
MIRT2174925	hsa-miR-200b	CLIP-seq
MIRT2174926	hsa-miR-200c	CLIP-seq
MIRT2174927	hsa-miR-429	CLIP-seq
MIRT2174928	hsa-miR-888	CLIP-seq
MIRT2478192	hsa-miR-3125	CLIP-seq
MIRT2478193	hsa-miR-34a	CLIP-seq
MIRT2478194	hsa-miR-34c-5p	CLIP-seq
MIRT2478195	hsa-miR-3613-3p	CLIP-seq
MIRT2478196	hsa-miR-371b-5p	CLIP-seq
MIRT2478197	hsa-miR-3916	CLIP-seq
MIRT2478198	hsa-miR-3928	CLIP-seq
MIRT2478199	hsa-miR-4261	CLIP-seq
MIRT2478200	hsa-miR-449a	CLIP-seq
MIRT2478201	hsa-miR-449b	CLIP-seq
MIRT2478202	hsa-miR-548ae	CLIP-seq
MIRT2478203	hsa-miR-548aj	CLIP-seq
MIRT2478204	hsa-miR-548am	CLIP-seq
MIRT2478205	hsa-miR-548x	CLIP-seq
MIRT2478206	hsa-miR-875-3p	CLIP-seq
MIRT2478207	hsa-miR-877	CLIP-seq
MIRT2174928	hsa-miR-888	CLIP-seq
MIRT2478192	hsa-miR-3125	CLIP-seq
MIRT2478193	hsa-miR-34a	CLIP-seq
MIRT2478194	hsa-miR-34c-5p	CLIP-seq
MIRT2478195	hsa-miR-3613-3p	CLIP-seq
MIRT2478196	hsa-miR-371b-5p	CLIP-seq
MIRT2478197	hsa-miR-3916	CLIP-seq
MIRT2478198	hsa-miR-3928	CLIP-seq
MIRT2478199	hsa-miR-4261	CLIP-seq
MIRT2478200	hsa-miR-449a	CLIP-seq
MIRT2478201	hsa-miR-449b	CLIP-seq
MIRT2478202	hsa-miR-548ae	CLIP-seq
MIRT2478203	hsa-miR-548aj	CLIP-seq
MIRT2478204	hsa-miR-548am	CLIP-seq
MIRT2478205	hsa-miR-548x	CLIP-seq
MIRT2478206	hsa-miR-875-3p	CLIP-seq
MIRT2478207	hsa-miR-877	CLIP-seq
MIRT2174928	hsa-miR-888	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0050790	Process	Regulation of catalytic activity	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

A8MVX0

Protein name

Rho guanine nucleotide exchange factor 33

Protein function

May act as a guanine-nucleotide releasing factor.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00621	RhoGEF	269 → 438	RhoGEF domain	Domain

Sequence

MEKTKTKQGENEHMPVNNPSTQIYQLQALASELKTGFTEAMQELSRIQHGEYALEEKVKS
CRCSMEEKVTEMKNSLNYFKEELSNAMSMIQAITSKQEEMQQKIEQLQQEKRRESRKVKA
KKTQKEEHSSQAGPAQAQGSPFRSINIPEPVLPSEDFTNLLPSQAYEKAQESRSVHVGDS
NVKGMMGPGVNPTTPEAEENLKSCLSADIQSKGHLPSGMWRQPKDGKEWGEEYVTKDHPD
KLKEAGQGRHSSLENVLCETSLAAKRQTVALELLESERKYVINISLILKIKATFQGSDGK
RNSKERSLFPGSLRYLVQQHLDLLHALQERVLKWPRQGVLGDLFLKLTNDENNFLDYYVA
YLRDLPECISLVHVVVLKEGDEEIKSDIYTLFFHIVQRIPEYLIHLQNVLKFTEQEHPDY
YLLLVCVQRLRVFISHYTLLFQCNEDLLIQKRKKLKKSSMAKLYKGLASQCANAGQDASP
TAGPEAVRDTGIHSEELLQPYPSAPSSGPAITHLMPPVKKSQQQQSLMESMQPGKPSDWE
LEGRKHERPESLLAPTQFCAAEQDVKALAGPLQAIPEMDFESSPAEPLGNVERSLRAPAE
LLPDARGFVPAAYEEFEYGGEIFALPAPYDEEPFQAPALFENCSPASSESSLDICFLRPV
SFAMEAERPEHPLQPLPKSATSPAGSSSAYKLEAAAQAHGKAKPLSRSLKEFPRAPPADG
VAPRLYSTRSSSGGRAPIKAERAAQAHGPAAAAVAARGASRTFFPQQRSQSEKQTYLEVR
REMHLEDTTRFCPKEERESEQTSFSDQNPRQDQKGGFRSSFRKLFKKKNGNATGEDFCGP
WGWW

Sequence length

844

Interactions

View interactions

	Reactome
			NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297	27903959

ARHGEF33 (Rho guanine nucleotide exchange factor 33)