GJE1 (gap junction protein epsilon 1)

Gene
Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
100126572
Gene name Gene Name - the full gene name approved by the HGNC.
Gap junction protein epsilon 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GJE1
Synonyms (NCBI Gene) Gene synonyms aliases
CX23
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6q24.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT021835 hsa-miR-132-3p Microarray 17612493
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all(8)
GO ID Ontology Definition Evidence Reference
GO:0000902 Process Cell morphogenesis IEA
GO:0002088 Process Lens development in camera-type eye IEA
GO:0005243 Function Gap junction channel activity IBA 21873635
GO:0005922 Component Connexin complex IBA 21873635
GO:0007267 Process Cell-cell signaling IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
Gene miRNA Gene ontology Other IDs Protein
UniProt ID A6NN92
Protein name Gap junction epsilon-1 protein (Connexin-23) (Cx23)
Protein function Mediates calcium-independent ATP release, suggesting activity as a hemichannel. Does not form functional gap junctions.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00029 Connexin 2 → 109 Connexin Family
PF00029 Connexin 101 → 196 Connexin Family
Tissue specificity TISSUE SPECIFICITY: Not detected in lens or retina. {ECO:0000269|PubMed:18849090}.
Sequence 
MSLNYIKNFYEGCVKPPTVIGQFHTLFFGSIRIFFLGVLGFAVYGNEALHFICDPDKREV
NLFCYNQFRPITPQVSFSALQLVIVLVPGALFHLYAACKSINQECILQKPIYTIIYILSV
LLRISLAAIAFWLQIYLFGFQVKSLYLCDARSLGENMIIRCMVPEHFEKTIFLIAINTFT
TITILLFVAEIFEIIFRRLYFPFRQ
Sequence length 205
Interactions View interactions