Gene Gene information from NCBI Gene database.
Entrez ID 100126335
Gene name MicroRNA 543
Gene symbol MIR543
Synonyms (NCBI Gene)
MIRN543hsa-mir-543mir-543
Chromosome 14
Chromosome location 14q32.31
Summary microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0003730 Function MRNA 3'-UTR binding IDA 24699721
GO:0016442 Component RISC complex IEA
GO:0030336 Process Negative regulation of cell migration IDA 24699721
GO:0035195 Process MiRNA-mediated post-transcriptional gene silencing IDA 25465621
GO:0035195 Process MiRNA-mediated post-transcriptional gene silencing IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A MI0005565
Interactions View interactions
Associated diseases Disease associations from ClinVar (Causal/Unknown) and external databases: GenCC, Orphanet, ClinGen, HPO, DisGeNET, CTD, GWAS Catalog.
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Associations from Text MiningDisease associations identified through Pubtator text-mining of PubMed literature.
Disease Name Relationship Type References
Acute Aortic Syndrome Associate 37505131
Acute Kidney Injury Inhibit 35442485
Adenocarcinoma Associate 25730011
Arthritis Rheumatoid Inhibit 37149637
beta Thalassemia Associate 34398996
Breast Neoplasms Inhibit 34787051
Carcinoma Renal Cell Associate 29101805
Carcinoma Signet Ring Cell Associate 25730011
Colorectal Neoplasms Associate 30842340, 32964969, 34549306
Dementia Associate 36352829