Obesity

Disease Term Disease ID Gene Symbol References
Obesity C0028754 ABCA4
ACACB 20882379
ACADM 20882379
ACADVL
ACHE 29273807
ACLY 20882379
ACP5 20882379
ADCY3 29311635
ADCY9 23563607
ADH1B 20882379
PARP1 20561897
ADRB1 12032746
ADRB2 15687340
ADRB3
AGRP
AGTR2
AHR 30813227, 27020609
AKT1 23954404
ALB
APOE 20975297
AQP7 16325777
ARG1 21552555
ARL3
STS 24497646
ARVCF
ZFHX3 29273807
RERE
ATRX
BBS1
BBS2
BBS4
BCHE 23073171, 18452903, 27163854, 23000450
BDNF 23563607
BLK
BRAF
BRCA2
CA3 20882379
CA4
CACNA1S
CASP1 22325453
ENTPD6 29273807
CD40 29035695
CD68 29035695
CEBPA 28242765
CEL
CES1 20975297
CIDEA 20975297
CLCN4
CNGB1
CNGA1
CNR1 18722357
COMT
COX7C 20882379
CPB2 16959692
CPE 15358678, 23434795
CRP 24042701
CRX
CS 20882379
CTF1 21803294
CTNNB1
CTSH
CTSS 21156398
CYB5A 20882379
CYP1B1 27036855
CYP2E1 23954404
CYP7A1
CYP19A1
DGKG 23563607
DCC
DDIT3 26655953
NQO1 17405841
DLG3
DMD
DNMT3A
DPYD 20882379
DUSP6
ECHS1 20882379
EFNB1 24098442
EGF
MEGF8
EIF2S3
ELN
EMD
EP300 26441656
ESR1 20667977
ETFDH 20882379
ETV5 23563607
F2 22841818
FAAH 20716455, 19103437
ACSL1 20882379
ACSL4
FASN 20882379
FCGR3B 29035695
FGF8
FGFR1
FGFR3
FHL1
FOXO3 23954404
FLII
FTL 20882379
GABRA3
GABRD
GATA4
GCG 20065960
GCK
GDI1
GFPT1 20882379
GH1 8923850
GIPR 23563607
GLDC 10873393
GLUL 20882379
GNAS 17062894
GNAT2 23563607
GNB3 16141801, 15961981
GP1BB
GPX1 15184668
GPX3 11328671, 19270708
GTF2I
GUCA1B
HADH 20882379
HCFC1
HCRT
HK2 20882379
HLA-DQB1
HLA-DRB1
HMGB2 20882379
HMOX1 19171794, 18334666, 18375438
HNF4A
HOXB3 22484627
HOXB5 22484627
HSD11B1 17628001, 21786805
HSPA5 26655953
HTR2A 17097612
HTR2C 17702092, 19142110
ICAM1 11782876
IDH3A
IDH3B
IGF2 11528401
IGFBP2 22537059
IL6 20141834, 24042701
IMPDH1
IDO1 27020609
INS 29035695, 8923850, 2777199, 11528401
PDX1
IRS1 23954404
ITGAM 29035695
ITPR3 19553259
ANOS1
KCNH2
KCNJ11
KCNMA1 21708048, 27605626
LBP 23349936
LDLR 25554529
LEP 25086370, 18515891, 23839791, 9502777, 9202122, 25554529, 24042701, 25551525, 19913045, 20122948, 26186301, 17517446, 9826672, 28698385
LEPR 17229951, 20567778, 29743445, 19913045, 25222487, 24263156, 22276206, 23563609, 3519326, 30689673
LIMK1
LMNA
LPL 18344982
SMAD4
MAK
MC3R
MC4R 18559663, 14764818, 23251400, 17143585, 16507637, 18454148, 10199800, 25163632, 11487744, 11443223, 12588803, 12970296, 20966905, 15448103, 10903343, 18801902, 12646665, 15486053, 14671178, 25332687, 19151714, 12690102, 20631012, 26179253, 19079261, 19301229, 22463805, 16274851, 19091795, 19079260, 17628007
ME1 19270708
MECP2
MMP9 21156398
ALDH6A1 20882379
MOG
MRC1 29035695
MMUT 20882379
MYH9
NCAM2 21552555
NEK2
NEUROD1
NF2
NHLH2 20808804
NINJ1 23563609
NPC1 19151714
NPHP1
NPY1R 20975297
NPY5R 10849579
NRL
NTRK2 15494731
OGG1 29709520
OTX2
P2RY11
SERPINE1 23819014
PAK3
PAX4
PAX5 22013104
PAX6
PCDH9 21552555
PCK1 20882379
PCSK1 18604207
PDE4D
PDE6A
PDE6G
PDGFB
PDE6B
ENPP1
PFKFB3 20882379
PLIN1 15001633
PMCH 12355323
POLG 12707443, 18546365
POMC 19153526, 16289378
POU3F4
PPARA 30738174, 11089532
PPARD 20176998, 16168052
PPARG 11089532, 9753710, 28242765
PRKAR1A 29367455
PRKAR2B 20975297
PRKCH 23563609
MAP2K5 23563607
PYY 16368708
PTEN
PTGS2 21156398
PTPN1 20075852, 10744717
RAP1A
RAP1B
RBP3
PRPH2
RFC2
RGR
RHO
RLBP1
ROM1
RP9
RP1
RP2
RPGR
RPE65
RPS6KA3
RREB1
SAG
SAT1 20882379
SCN1A
CCL2 29035695
SHOX
SIM1 16924270
SKI
SLC8A1 23563609
SLC22A1 20956498
SLC22A3 27401566
SLC22A2 27401566
SMARCB1
SOD1 24042701
SOD2 16317704, 30738174, 23956348
SOX2
SOX3
SOX10
SREBF1 10900012
SRY
ABCC8
SYP
TACR3
TAF1
TBX1
TBCE 19557161
TBX3
HNF1A
TCOF1
TF 20882379
TFAP2B 23563607, 19557161
TFRC 17062801, 20882379
TSPAN7
TNF 29035695, 9502777, 11328671, 20141834
TNFRSF1B 11782876
TUB
TULP1
HIRA
TNFSF4
UBE3A
UCP1 15592485
UCP2 11381268
UCP3 9769326
UFD1
UQCRC2 20882379
USH2A
CLRN1
KDM6A
VLDLR 20975297
BEST1
TRPV1 17347480
CLIP2
WT1
ZNF711
ZNF41
ALMS1 29079548
GLRA3 25963547
KMT2D
IFT88
AKAP1 20975297
MKKS
USP9X
NR0B2
CUL4B
KLF11
OFD1
KCNAB2
GAS7 19270708
AKR1C3 20882379
PEX11A 30585412
SUCLG2 20882379
SUCLA2 20882379
HESX1
FGF17
PROM1
NR1I2 20869355
BAZ1B
AIP
USP8
PRPF4
PRPF3
SLC16A7 20882379
LRAT
CD163 29035695
NRXN3 21552555, 23563607
ADIPOQ 10092513, 14617771
NRXN1
HS6ST1
ARHGEF6
H6PD
GTF2IRD1
CARTPT
SEC24C
SDC3
IFT140
FRMPD4
HDAC4
DHX38
TRIM66 23563607
ARNT2
MED12
NR1I3 20869355
NR2E3
HUWE1
NAMPT 23834033
ATP6AP2
TOPORS
APC2
SEMA3A
RAPGEF3 29273807
MERTK
DEAF1
PRPF8
FARS2 23563609
RAI1 19116176, 15459175
SDCCAG8 20421936
ALDH1L1 20882379
PNPLA6
IFT27
MID2
IL1RAPL1
PNKP
CNKSR2
ZNF365
TRIM32
RAB21 29273807
FAIM2 21935397
SNRNP200
MYT1L 21990140, 26240977
IQSEC2
POGZ
TBC1D1 18325908, 16893906, 18931681
ZFR2 29273807
SYNE2
DDHD2 24517879, 25417924, 23176823, 24337409
TTC28 21552555
SYNE1
ARHGEF18
ADNP
SIRT3 23956348
SIRT1 24184811
CRB1
ARL2BP
PDSS1
FLRT3
MTCH2 19079261
FTSJ1
PRPF6
FSCN2
SIN3A
SH2B1 19079261, 23563607, 23160192
NSMF
APPL1
PRPF31
IFT172
FGF21 26797127, 24184811
TBL2
AFF4 25730767
BBS9
RBMX
SETD2
SH3KBP1
SCAPER 30723319
IMPG2
ZBTB7B 29273807
WDPCP
MLXIPL
TNNI3K 22484627, 23563607
ANGPTL4 28842503
DCXR 20882379
NIN
SUFU
RAB23
GHRL
WWOX 21552555
CYCS 16317704
WNT4
PRMT7
MAGEL2
UGT1A10 25246029
UGT1A8 25246029
UGT1A7 25246029
UGT1A6 25246029
UGT1A5 25246029
LZTFL1
UGT1A9 25246029
UGT1A4 25246029
UGT1A1 25246029
UGT1A3 25246029
IL17RD
CNNM2
AHI1
MKS1
PHIP
BBS7
FGGY 29220483
SOX6 19714249
POMGNT1
CHD7
PACS1 23563609
WDR11
ERMARD
SPATA7
KIZ
KLHL7
CYP26B1 20882379
INPP5E 19668215
MRPS22 22013104
KIDINS220
RPTOR 23563607
HACE1
KIAA1549
SLC7A14
SUGP1 25246029
AGBL5
PROK2
STEEP1
PRDM16
SEMA4A
NSD1
ATPAF1 20882379
UPF3B
RSRC2
MTMR9 17855449
KCTD15 19079261
FTO 18159244, 23563607, 21544081, 21552555, 19079260, 21935397, 22484627, 19079261, 19553259, 19918250, 19151714, 23563609, 20421936, 21076408, 21706003, 17496892
CCDC28B
TMEM43
NEIL1 16446448, 21285402
BBS10
ZNF408
EHMT1
ALG13
RABEP2 23563607
DHDDS
IFT74
CEP290
SPG11
ALPK1 22484627
PNPLA3 25246029
SPRY4
LAS1L
TRAPPC9
ARL6
FAM161A
PHF6
CCDC77 23563609
KISS1R
SLC9A7
CEP19
SHANK3
WNT3A 28242765
SEC16B 22484627
TMEM67
CDHR1
BBIP1
REEP6
MRAP2 26795956
LACTB 18344982
RAB39B
TTC8
CANT1
PROKR2
TMEM18 19079261
BBS5
ZNF513
GNPDA2 19079261
PPARGC1B 30738174
POC5 23563607
HGSNAT
PTCHD1
SOCS2-AS1 25246029
RDH12
APCDD1 28242765
PPM1L 18344982
CFAP418
VPS13B
LINGO2 23563607
LRRN4 18159244
BBS12
ZNF169 29273807
ARX
RMST 23563609
ARL13B
JMJD1C
CADM2 23563607
NEGR1 19079261
HS6ST3 23563607
KSR2 29273807
TTC28-AS1 21552555
CCDC141
EYS
ZNF81
KIF7
CERKL
LHFPL3 21552555
PCARE
FEZF1
USP27X
EML6 19553259
LINC01122 23563607
CASC15 19151714
HOXB-AS3 22484627
MIR130A 28242765
MIR130B 28242765
MIR184 23954404
MIR21 23954404
MIR34A 23834033
BDNF-AS 21708048, 23563607
PRCD
GHRLOS
KCNJ18
BCDIN3D-AS1 23563607
FPGT-TNNI3K 23563607, 22484627
LINC01524 23563607
SCN1A-AS1
LRRC53 22484627
LINC02465 22484627
LINC02055 23563607
CRYZL2P-SEC16B 22484627
Obesity, Morbid C0028756 ADCY3 29311637
BDNF 21708048
KCNMA1 21708048
LEP 15070752, 9500540
LEPR 9537324
MC4R 29273807, 29311635
PPARG
KSR2 29273807
Obesity due to melanocortin 4 receptor deficiency C4273958, 71529 MC4R 10903343
Obesity due to leptin receptor gene deficiency 179494 LEPR
NON RARE IN EUROPE: Obesity due to MC3R deficiency 217031 MC3R
Obesity due to SIM1 deficiency 369873 SIM1
Obesity due to CEP19 deficiency 397615 CEP19
Obesity due to congenital leptin deficiency 66628 LEP
Obesity due to pro-opiomelanocortin deficiency 71526 POMC
Obesity due to prohormone convertase I deficiency 71528 PCSK1
Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency 329249 SH2B1