Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	55689
Gene name	YEATS domain containing 2
Gene symbol	YEATS2
Synonyms (NCBI Gene)	FAME4
Chromosome	3
Chromosome location	3q27.1
Summary	Summary: The protein encoded by this gene is a scaffolding subunit of the ATAC complex, which is a complex with acetyltransferase activity on histones H3 and H4. Alternative splicing results in multiple transcript variants encoding different isoforms. [pr

302 Show/Hide all (302)

miRTarBase ID	miRNA	Experiments	Reference
MIRT052158	hsa-let-7b-5p	CLASH	23622248
MIRT043982	hsa-miR-378a-5p	CLASH	23622248
MIRT042732	hsa-miR-345-5p	CLASH	23622248
MIRT439274	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT439273	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT439274	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT439273	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT1498409	hsa-miR-1205	CLIP-seq
MIRT1498410	hsa-miR-1224-3p	CLIP-seq
MIRT1498411	hsa-miR-1270	CLIP-seq
MIRT1498412	hsa-miR-1273f	CLIP-seq
MIRT1498413	hsa-miR-1281	CLIP-seq
MIRT1498414	hsa-miR-1285	CLIP-seq
MIRT1498415	hsa-miR-1287	CLIP-seq
MIRT1498416	hsa-miR-143	CLIP-seq
MIRT1498417	hsa-miR-150	CLIP-seq
MIRT1498418	hsa-miR-15a	CLIP-seq
MIRT1498419	hsa-miR-15b	CLIP-seq
MIRT1498420	hsa-miR-16	CLIP-seq
MIRT1498421	hsa-miR-195	CLIP-seq
MIRT1498422	hsa-miR-197	CLIP-seq
MIRT1498423	hsa-miR-1972	CLIP-seq
MIRT1498424	hsa-miR-1976	CLIP-seq
MIRT1498425	hsa-miR-214	CLIP-seq
MIRT1498426	hsa-miR-3135b	CLIP-seq
MIRT1498427	hsa-miR-3180	CLIP-seq
MIRT1498428	hsa-miR-3180-3p	CLIP-seq
MIRT1498429	hsa-miR-3187-5p	CLIP-seq
MIRT1498430	hsa-miR-3196	CLIP-seq
MIRT1498431	hsa-miR-323b-3p	CLIP-seq
MIRT1498432	hsa-miR-329	CLIP-seq
MIRT1498433	hsa-miR-3619-5p	CLIP-seq
MIRT1498434	hsa-miR-3622b-5p	CLIP-seq
MIRT1498435	hsa-miR-362-3p	CLIP-seq
MIRT1498436	hsa-miR-3663-5p	CLIP-seq
MIRT1498437	hsa-miR-3667-3p	CLIP-seq
MIRT1498438	hsa-miR-3674	CLIP-seq
MIRT1498439	hsa-miR-3675-5p	CLIP-seq
MIRT1498440	hsa-miR-3690	CLIP-seq
MIRT1498441	hsa-miR-378g	CLIP-seq
MIRT1498442	hsa-miR-3944-3p	CLIP-seq
MIRT1498443	hsa-miR-3945	CLIP-seq
MIRT1498444	hsa-miR-424	CLIP-seq
MIRT1498445	hsa-miR-4251	CLIP-seq
MIRT1498446	hsa-miR-4253	CLIP-seq
MIRT1498447	hsa-miR-4254	CLIP-seq
MIRT1498448	hsa-miR-4269	CLIP-seq
MIRT1498449	hsa-miR-4287	CLIP-seq
MIRT1498450	hsa-miR-4314	CLIP-seq
MIRT1498451	hsa-miR-4329	CLIP-seq
MIRT1498452	hsa-miR-4438	CLIP-seq
MIRT1498453	hsa-miR-4469	CLIP-seq
MIRT1498454	hsa-miR-4486	CLIP-seq
MIRT1498455	hsa-miR-4490	CLIP-seq
MIRT1498456	hsa-miR-4492	CLIP-seq
MIRT1498457	hsa-miR-4498	CLIP-seq
MIRT1498458	hsa-miR-4633-3p	CLIP-seq
MIRT1498459	hsa-miR-4683	CLIP-seq
MIRT1498460	hsa-miR-4685-3p	CLIP-seq
MIRT1498461	hsa-miR-4708-5p	CLIP-seq
MIRT1498462	hsa-miR-4713-5p	CLIP-seq
MIRT1498463	hsa-miR-4716-5p	CLIP-seq
MIRT1498464	hsa-miR-4719	CLIP-seq
MIRT1498465	hsa-miR-4740-3p	CLIP-seq
MIRT1498466	hsa-miR-4770	CLIP-seq
MIRT1498467	hsa-miR-4781-3p	CLIP-seq
MIRT1498468	hsa-miR-497	CLIP-seq
MIRT1498469	hsa-miR-5095	CLIP-seq
MIRT1498470	hsa-miR-5096	CLIP-seq
MIRT1498471	hsa-miR-512-3p	CLIP-seq
MIRT1498472	hsa-miR-566	CLIP-seq
MIRT1498473	hsa-miR-612	CLIP-seq
MIRT1498474	hsa-miR-620	CLIP-seq
MIRT1498475	hsa-miR-642a	CLIP-seq
MIRT1498476	hsa-miR-759	CLIP-seq
MIRT1498477	hsa-miR-761	CLIP-seq
MIRT1498478	hsa-miR-762	CLIP-seq
MIRT1498479	hsa-miR-935	CLIP-seq
MIRT1498456	hsa-miR-4492	CLIP-seq
MIRT1498457	hsa-miR-4498	CLIP-seq
MIRT1498478	hsa-miR-762	CLIP-seq
MIRT2150115	hsa-miR-1197	CLIP-seq
MIRT2150116	hsa-miR-122	CLIP-seq
MIRT2150117	hsa-miR-193a-3p	CLIP-seq
MIRT2150118	hsa-miR-193b	CLIP-seq
MIRT1498423	hsa-miR-1972	CLIP-seq
MIRT1498426	hsa-miR-3135b	CLIP-seq
MIRT1498432	hsa-miR-329	CLIP-seq
MIRT1498434	hsa-miR-3622b-5p	CLIP-seq
MIRT1498435	hsa-miR-362-3p	CLIP-seq
MIRT2150119	hsa-miR-3922-5p	CLIP-seq
MIRT2150120	hsa-miR-4261	CLIP-seq
MIRT1498448	hsa-miR-4269	CLIP-seq
MIRT2150121	hsa-miR-4286	CLIP-seq
MIRT1498452	hsa-miR-4438	CLIP-seq
MIRT1498456	hsa-miR-4492	CLIP-seq
MIRT1498457	hsa-miR-4498	CLIP-seq
MIRT2150122	hsa-miR-4645-5p	CLIP-seq
MIRT2150123	hsa-miR-4673	CLIP-seq
MIRT2150124	hsa-miR-4735-5p	CLIP-seq
MIRT2150125	hsa-miR-4753-5p	CLIP-seq
MIRT2150126	hsa-miR-4755-3p	CLIP-seq
MIRT2150127	hsa-miR-4763-5p	CLIP-seq
MIRT2150128	hsa-miR-4775	CLIP-seq
MIRT1498469	hsa-miR-5095	CLIP-seq
MIRT2150129	hsa-miR-590-3p	CLIP-seq
MIRT2150130	hsa-miR-596	CLIP-seq
MIRT1498478	hsa-miR-762	CLIP-seq
MIRT2150116	hsa-miR-122	CLIP-seq
MIRT2370324	hsa-miR-1226	CLIP-seq
MIRT1498413	hsa-miR-1281	CLIP-seq
MIRT1498414	hsa-miR-1285	CLIP-seq
MIRT2370325	hsa-miR-1292	CLIP-seq
MIRT2370326	hsa-miR-1297	CLIP-seq
MIRT2370327	hsa-miR-1343	CLIP-seq
MIRT1498418	hsa-miR-15a	CLIP-seq
MIRT1498419	hsa-miR-15b	CLIP-seq
MIRT1498420	hsa-miR-16	CLIP-seq
MIRT1498421	hsa-miR-195	CLIP-seq
MIRT1498422	hsa-miR-197	CLIP-seq
MIRT1498425	hsa-miR-214	CLIP-seq
MIRT2370328	hsa-miR-26a	CLIP-seq
MIRT2370329	hsa-miR-26b	CLIP-seq
MIRT2370330	hsa-miR-3074-5p	CLIP-seq
MIRT1498429	hsa-miR-3187-5p	CLIP-seq
MIRT1498432	hsa-miR-329	CLIP-seq
MIRT1498433	hsa-miR-3619-5p	CLIP-seq
MIRT1498434	hsa-miR-3622b-5p	CLIP-seq
MIRT1498435	hsa-miR-362-3p	CLIP-seq
MIRT1498436	hsa-miR-3663-5p	CLIP-seq
MIRT2370331	hsa-miR-3664-3p	CLIP-seq
MIRT2370332	hsa-miR-3682-5p	CLIP-seq
MIRT2370333	hsa-miR-3689a-5p	CLIP-seq
MIRT2370334	hsa-miR-3689b	CLIP-seq
MIRT2370335	hsa-miR-3689e	CLIP-seq
MIRT2370336	hsa-miR-3689f	CLIP-seq
MIRT1498441	hsa-miR-378g	CLIP-seq
MIRT2370337	hsa-miR-3929	CLIP-seq
MIRT1498442	hsa-miR-3944-3p	CLIP-seq
MIRT1498443	hsa-miR-3945	CLIP-seq
MIRT1498444	hsa-miR-424	CLIP-seq
MIRT1498446	hsa-miR-4253	CLIP-seq
MIRT2150120	hsa-miR-4261	CLIP-seq
MIRT1498448	hsa-miR-4269	CLIP-seq
MIRT2370338	hsa-miR-4291	CLIP-seq
MIRT2370339	hsa-miR-4310	CLIP-seq
MIRT1498450	hsa-miR-4314	CLIP-seq
MIRT2370340	hsa-miR-4419b	CLIP-seq
MIRT1498452	hsa-miR-4438	CLIP-seq
MIRT2370341	hsa-miR-4462	CLIP-seq
MIRT2370342	hsa-miR-4465	CLIP-seq
MIRT2370343	hsa-miR-4471	CLIP-seq
MIRT2370344	hsa-miR-4478	CLIP-seq
MIRT1498454	hsa-miR-4486	CLIP-seq
MIRT1498456	hsa-miR-4492	CLIP-seq
MIRT2370345	hsa-miR-4496	CLIP-seq
MIRT1498457	hsa-miR-4498	CLIP-seq
MIRT2370346	hsa-miR-4514	CLIP-seq
MIRT2370347	hsa-miR-4642	CLIP-seq
MIRT2370348	hsa-miR-4652-3p	CLIP-seq
MIRT2370349	hsa-miR-4679	CLIP-seq
MIRT2370350	hsa-miR-4685-5p	CLIP-seq
MIRT2370351	hsa-miR-4692	CLIP-seq
MIRT1498463	hsa-miR-4716-5p	CLIP-seq
MIRT2370352	hsa-miR-4733-3p	CLIP-seq
MIRT2150124	hsa-miR-4735-5p	CLIP-seq
MIRT1498465	hsa-miR-4740-3p	CLIP-seq
MIRT2150128	hsa-miR-4775	CLIP-seq
MIRT1498467	hsa-miR-4781-3p	CLIP-seq
MIRT2370353	hsa-miR-483-3p	CLIP-seq
MIRT2370354	hsa-miR-483-5p	CLIP-seq
MIRT2370355	hsa-miR-495	CLIP-seq
MIRT1498468	hsa-miR-497	CLIP-seq
MIRT1498469	hsa-miR-5095	CLIP-seq
MIRT1498470	hsa-miR-5096	CLIP-seq
MIRT2370356	hsa-miR-510	CLIP-seq
MIRT2370357	hsa-miR-512-5p	CLIP-seq
MIRT2370358	hsa-miR-515-5p	CLIP-seq
MIRT2150129	hsa-miR-590-3p	CLIP-seq
MIRT1498473	hsa-miR-612	CLIP-seq
MIRT2370359	hsa-miR-615-5p	CLIP-seq
MIRT2370360	hsa-miR-628-5p	CLIP-seq
MIRT1498477	hsa-miR-761	CLIP-seq
MIRT1498478	hsa-miR-762	CLIP-seq
MIRT2370361	hsa-miR-873	CLIP-seq
MIRT2370362	hsa-miR-885-3p	CLIP-seq
MIRT2370363	hsa-miR-922	CLIP-seq
MIRT1498479	hsa-miR-935	CLIP-seq
MIRT2397120	hsa-miR-127-3p	CLIP-seq
MIRT2397121	hsa-miR-330-3p	CLIP-seq
MIRT1498432	hsa-miR-329	CLIP-seq
MIRT1498435	hsa-miR-362-3p	CLIP-seq
MIRT1498448	hsa-miR-4269	CLIP-seq
MIRT1498452	hsa-miR-4438	CLIP-seq
MIRT2150124	hsa-miR-4735-5p	CLIP-seq
MIRT1498469	hsa-miR-5095	CLIP-seq
MIRT2150116	hsa-miR-122	CLIP-seq
MIRT2370324	hsa-miR-1226	CLIP-seq
MIRT2663967	hsa-miR-125a-3p	CLIP-seq
MIRT1498411	hsa-miR-1270	CLIP-seq
MIRT2663968	hsa-miR-1271	CLIP-seq
MIRT2663969	hsa-miR-128	CLIP-seq
MIRT1498413	hsa-miR-1281	CLIP-seq
MIRT2370326	hsa-miR-1297	CLIP-seq
MIRT2370327	hsa-miR-1343	CLIP-seq
MIRT1498417	hsa-miR-150	CLIP-seq
MIRT1498422	hsa-miR-197	CLIP-seq
MIRT2663970	hsa-miR-2117	CLIP-seq
MIRT2370328	hsa-miR-26a	CLIP-seq
MIRT2370329	hsa-miR-26b	CLIP-seq
MIRT2663971	hsa-miR-27a	CLIP-seq
MIRT2663972	hsa-miR-27b	CLIP-seq
MIRT1498426	hsa-miR-3135b	CLIP-seq
MIRT1498432	hsa-miR-329	CLIP-seq
MIRT2663973	hsa-miR-342-3p	CLIP-seq
MIRT1498435	hsa-miR-362-3p	CLIP-seq
MIRT2663974	hsa-miR-3652	CLIP-seq
MIRT1498436	hsa-miR-3663-5p	CLIP-seq
MIRT2663975	hsa-miR-3686	CLIP-seq
MIRT1498440	hsa-miR-3690	CLIP-seq
MIRT2663976	hsa-miR-383	CLIP-seq
MIRT2663977	hsa-miR-3934	CLIP-seq
MIRT1498442	hsa-miR-3944-3p	CLIP-seq
MIRT2663978	hsa-miR-411	CLIP-seq
MIRT1498447	hsa-miR-4254	CLIP-seq
MIRT1498448	hsa-miR-4269	CLIP-seq
MIRT2663979	hsa-miR-4273	CLIP-seq
MIRT1498449	hsa-miR-4287	CLIP-seq
MIRT2663980	hsa-miR-4430	CLIP-seq
MIRT2663981	hsa-miR-4436b-5p	CLIP-seq
MIRT1498452	hsa-miR-4438	CLIP-seq
MIRT2663982	hsa-miR-4446-3p	CLIP-seq
MIRT2370342	hsa-miR-4465	CLIP-seq
MIRT1498453	hsa-miR-4469	CLIP-seq
MIRT1498456	hsa-miR-4492	CLIP-seq
MIRT1498457	hsa-miR-4498	CLIP-seq
MIRT2370348	hsa-miR-4652-3p	CLIP-seq
MIRT1498459	hsa-miR-4683	CLIP-seq
MIRT1498460	hsa-miR-4685-3p	CLIP-seq
MIRT2370350	hsa-miR-4685-5p	CLIP-seq
MIRT2663983	hsa-miR-4695-3p	CLIP-seq
MIRT1498462	hsa-miR-4713-5p	CLIP-seq
MIRT1498463	hsa-miR-4716-5p	CLIP-seq
MIRT2370352	hsa-miR-4733-3p	CLIP-seq
MIRT2150124	hsa-miR-4735-5p	CLIP-seq
MIRT2663984	hsa-miR-4742-3p	CLIP-seq
MIRT2663985	hsa-miR-4772-3p	CLIP-seq
MIRT2150128	hsa-miR-4775	CLIP-seq
MIRT1498467	hsa-miR-4781-3p	CLIP-seq
MIRT2370354	hsa-miR-483-5p	CLIP-seq
MIRT1498469	hsa-miR-5095	CLIP-seq
MIRT1498470	hsa-miR-5096	CLIP-seq
MIRT2663986	hsa-miR-579	CLIP-seq
MIRT2150129	hsa-miR-590-3p	CLIP-seq
MIRT1498474	hsa-miR-620	CLIP-seq
MIRT2370360	hsa-miR-628-5p	CLIP-seq
MIRT1498475	hsa-miR-642a	CLIP-seq
MIRT1498478	hsa-miR-762	CLIP-seq
MIRT2663987	hsa-miR-764	CLIP-seq
MIRT2663988	hsa-miR-96	CLIP-seq
MIRT2150116	hsa-miR-122	CLIP-seq
MIRT2370324	hsa-miR-1226	CLIP-seq
MIRT2663968	hsa-miR-1271	CLIP-seq
MIRT1498413	hsa-miR-1281	CLIP-seq
MIRT2370326	hsa-miR-1297	CLIP-seq
MIRT2370327	hsa-miR-1343	CLIP-seq
MIRT2663970	hsa-miR-2117	CLIP-seq
MIRT2370328	hsa-miR-26a	CLIP-seq
MIRT2370329	hsa-miR-26b	CLIP-seq
MIRT2370330	hsa-miR-3074-5p	CLIP-seq
MIRT1498426	hsa-miR-3135b	CLIP-seq
MIRT1498432	hsa-miR-329	CLIP-seq
MIRT1498435	hsa-miR-362-3p	CLIP-seq
MIRT2663974	hsa-miR-3652	CLIP-seq
MIRT2663975	hsa-miR-3686	CLIP-seq
MIRT2663976	hsa-miR-383	CLIP-seq
MIRT1498448	hsa-miR-4269	CLIP-seq
MIRT2663979	hsa-miR-4273	CLIP-seq
MIRT1498449	hsa-miR-4287	CLIP-seq
MIRT2663980	hsa-miR-4430	CLIP-seq
MIRT1498452	hsa-miR-4438	CLIP-seq
MIRT2663982	hsa-miR-4446-3p	CLIP-seq
MIRT2370342	hsa-miR-4465	CLIP-seq
MIRT1498453	hsa-miR-4469	CLIP-seq
MIRT1498456	hsa-miR-4492	CLIP-seq
MIRT1498457	hsa-miR-4498	CLIP-seq
MIRT2370348	hsa-miR-4652-3p	CLIP-seq
MIRT1498460	hsa-miR-4685-3p	CLIP-seq
MIRT2370350	hsa-miR-4685-5p	CLIP-seq
MIRT1498462	hsa-miR-4713-5p	CLIP-seq
MIRT2695406	hsa-miR-4722-3p	CLIP-seq
MIRT2370352	hsa-miR-4733-3p	CLIP-seq
MIRT2150124	hsa-miR-4735-5p	CLIP-seq
MIRT2663984	hsa-miR-4742-3p	CLIP-seq
MIRT2663985	hsa-miR-4772-3p	CLIP-seq
MIRT2150128	hsa-miR-4775	CLIP-seq
MIRT1498469	hsa-miR-5095	CLIP-seq
MIRT2663986	hsa-miR-579	CLIP-seq
MIRT2150129	hsa-miR-590-3p	CLIP-seq
MIRT1498475	hsa-miR-642a	CLIP-seq
MIRT1498478	hsa-miR-762	CLIP-seq
MIRT2663988	hsa-miR-96	CLIP-seq

34 Show/Hide all (34)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	18838386
GO:0003714	Function	Transcription corepressor activity	IDA	18838386
GO:0005515	Function	Protein binding	IPI	18838386
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006338	Process	Chromatin remodeling	IBA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IMP	19936620
GO:0006355	Process	Regulation of DNA-templated transcription	ISS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IDA	22055187
GO:0006357	Process	Regulation of transcription by RNA polymerase II	ISS
GO:0017025	Function	TBP-class protein binding	IPI	18838386
GO:0035267	Component	NuA4 histone acetyltransferase complex	IBA
GO:0042393	Function	Histone binding	IBA
GO:0042393	Function	Histone binding	IDA	27103431
GO:0045995	Process	Regulation of embryonic development	IEA
GO:0045995	Process	Regulation of embryonic development	ISO
GO:0045995	Process	Regulation of embryonic development	ISS
GO:0051302	Process	Regulation of cell division	IDA	20562830
GO:0051302	Process	Regulation of cell division	IEA
GO:0051302	Process	Regulation of cell division	ISS
GO:0051726	Process	Regulation of cell cycle	IEA
GO:0051726	Process	Regulation of cell cycle	IMP	19103755
GO:0051726	Process	Regulation of cell cycle	ISS
GO:0072686	Component	Mitotic spindle	IEA
GO:0072686	Component	Mitotic spindle	NAS	20562830
GO:0140030	Function	Modification-dependent protein binding	IDA	27103431
GO:0140566	Function	Histone reader activity	IDA	27103431
GO:0140672	Component	ATAC complex	IBA
GO:0140672	Component	ATAC complex	IDA	18838386, 19936620
GO:0140672	Component	ATAC complex	IEA
GO:0140672	Component	ATAC complex	ISO

MIM	HGNC	e!Ensembl
613373	25489	ENSG00000163872

Q9ULM3

Protein name

YEATS domain-containing protein 2

Protein function

Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (PubMed:18838386, PubMed:19103755, PubMed:27103431). YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys

PDB

5IQL , 5XNV , 6LSD , 7EIE

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03366	YEATS	231 → 313	YEATS family	Domain

Sequence

MSGIKRTIKETDPDYEDVSVALPNKRHKAIENSARDAAVQKIETIIKEQFALEMKNKEHE
IEVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGSKTCDTMVFNHPAIKKFLESPS
RSSSPANQRAETPSANHSESDSLSQHNDFLSDKDNNSNMDIEERLSNNMEQRPSRNTGRD
TSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRG
SRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKR
IDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSLPLTIP
APVKASSPIKQSHEPVPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQKVTFC
SHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPT
STPVHVKQGTAGSVINNPYVIMDKQPGQVIGATTPSTGSPTNKISTASQVSQGTGSPVPK
IHGSSFVTSTVKQEDSLFASMPPLCPIGSHPKVQSPKPITGGLGAFTKVIIKQEPGEAPH
VPATGAASQSPLPQYVTVKGGHMIAVSPQKQVITPGEGIAQSAKVQPSKVVGVPVGSALP
STVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKA
QVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQG
AILRATNNANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGP
GGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQTLK
VISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPA
VALSANGPAQQSEGMAPVSSSTVSSVTKTSGQQQVCVSQATVGTCKAATPTVVSATSLVP
TPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQSF
STSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNY
VIKIDHLETIQQLLTAVVKKIPLITAKSEDASCFSAKSVEQYYGWNIGKRRAAEWQRAMT
MRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQIDSE
PECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKF
YLPPTPGSEFIGDVTQKIGITLQPVALHRNVYASVVEDMILKATEQLVNDILRQALAVGY
QTASHNRIPKEITVSNIHQAICNIPFLDFLTNKHMGILNEDQ

Sequence length

1422

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal. Show/Hide Unknown Diseases (12)
BENIGN ADULT FAMILIAL MYOCLONIC EPILEPSY	—	Disgenet, GWAS catalog Disgenet, GWAS catalog	31539032	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast ductal adenocarcinoma	Uncertain significance	ClinVar	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, PANCREATIC DUCTAL	—	CTD	34686948	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Epilepsy, familial adult myoclonic, 4	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	ClinVar ClinVar, Disgenet, HPO ClinVar, Disgenet, HPO ClinVar, Disgenet, HPO	—	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
FAMILIAL ADULT MYOCLONIC EPILEPSY	—	Orphanet	31539032	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	36810956	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	37945903	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	37945903	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSYCHIATRIC DISORDER	—	GWAS catalog	38469033	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
STEVENS-JOHNSON SYNDROME	—	GWAS catalog	35170024	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TOXIC EPIDERMAL NECROLYSIS	—	GWAS catalog	35170024	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
YEATS2-related disorder	Uncertain significance; Likely benign	ClinVar	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining Show/Hide Text Mining Associations (10)
Autistic Disorder	Autism	GWASDB_DG	22843504		★★★★★ ★☆☆☆☆ Found in Text Mining only
Benign adult familial myoclonic epilepsy	Benign Myoclonic Epilepsy	BEFREE	31539032		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Benign adult familial myoclonic epilepsy	Benign Myoclonic Epilepsy	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinogenesis	Carcinogenesis	Pubtator	29057918	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	38186679	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	37469197	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liposarcoma	Liposarcoma	Pubtator	29610390	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	29057918		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	34587874, 40216980	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	34587874	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
MARCHF6	3	["Benign myoclonic epilepsy","Familial adult myoclonic epilepsy","Adult myoclonic epilepsy"]	[]	5	["Disgenet (Benign myoclonic epilepsy)","ClinVar (Familial adult myoclonic epilepsy)","Disgenet (Familial adult myoclonic epilepsy)","HPO (Familial adult myoclonic epilepsy)","Orphanet (Adult myoclonic epilepsy)"]
SAMD12	3	["Benign myoclonic epilepsy","Familial adult myoclonic epilepsy","Adult myoclonic epilepsy"]	[]	6	["Disgenet (Benign myoclonic epilepsy)","GWAS catalog (Benign myoclonic epilepsy)","ClinVar (Familial adult myoclonic epilepsy)","Disgenet (Familial adult myoclonic epilepsy)","HPO (Familial adult myoclonic epilepsy)","Orphanet (Adult myoclonic epilepsy)"]
TNRC6A	2	["Familial adult myoclonic epilepsy","Adult myoclonic epilepsy"]	[]	4	["ClinVar (Familial adult myoclonic epilepsy)","Disgenet (Familial adult myoclonic epilepsy)","HPO (Familial adult myoclonic epilepsy)","Orphanet (Adult myoclonic epilepsy)"]
RAPGEF2	2	["Familial adult myoclonic epilepsy","Adult myoclonic epilepsy"]	[]	4	["ClinVar (Familial adult myoclonic epilepsy)","Disgenet (Familial adult myoclonic epilepsy)","HPO (Familial adult myoclonic epilepsy)","Orphanet (Adult myoclonic epilepsy)"]
CNTN2	3	["Benign myoclonic epilepsy","Familial adult myoclonic epilepsy","Adult myoclonic epilepsy"]	[]	4	["Disgenet (Benign myoclonic epilepsy)","GWAS catalog (Benign myoclonic epilepsy)","ClinVar (Familial adult myoclonic epilepsy)","Orphanet (Adult myoclonic epilepsy)"]

YEATS2 (YEATS domain containing 2)

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