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Gene Gene information from NCBI Gene database.
Entrez ID 389668
Gene name XK related 9
Gene symbol XKR9
Synonyms (NCBI Gene)
XRG9hXKR9
Chromosome 8
Chromosome location 8q13.3
miRNA miRNA information provided by mirtarbase database.
727 Show/Hide all (727)
miRTarBase ID miRNA Experiments Reference
MIRT046530 hsa-miR-15b-5p CLASH 23622248
MIRT498872 hsa-miR-3662 HITS-CLIP 23313552
MIRT498871 hsa-miR-8084 HITS-CLIP 23313552
MIRT691252 hsa-miR-7153-3p HITS-CLIP 23313552
MIRT498870 hsa-miR-1272 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6 Show/Hide all (6)
GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane IEA
GO:0006915 Process Apoptotic process IEA
GO:0016020 Component Membrane IBA
GO:0016020 Component Membrane IEA
GO:0017128 Function Phospholipid scramblase activity ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5GH70
Protein name XK-related protein 9 (hXKR9) [Cleaved into: XK-related protein 9, processed form]
Protein function [XK-related protein 9, processed form]: Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface (PubMed:25231987). Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and act
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09815 XK-related 9 → 346 XK-related protein Family
Sequence
Sequence length 373
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway
Efferocytosis
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
7
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Show/Hide Unknown Diseases (7)
Phenotype Name Clinical Significance Source Reference Evidence Score
CHRONIC OBSTRUCTIVE PULMONARY DISEASE — GWAS catalog 37069358
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Familial cancer of breast Uncertain significance ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Gastric cancer Uncertain significance ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HEMORRHOID — GWAS catalog 33888516
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HYPOSPADIAS — GWAS catalog 25108383
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations