Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	79735
Gene name	TBC1 domain family member 17
Gene symbol	TBC1D17
Synonyms (NCBI Gene)	-
Chromosome	19
Chromosome location	19q13.33

96 Show/Hide all (96)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018707	hsa-miR-335-5p	Microarray	18185580
MIRT151941	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT151932	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT151941	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT151931	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT151945	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT151935	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT151950	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT151932	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT1412501	hsa-miR-1228	CLIP-seq
MIRT1412502	hsa-miR-1913	CLIP-seq
MIRT1412503	hsa-miR-21	CLIP-seq
MIRT1412504	hsa-miR-214	CLIP-seq
MIRT1412505	hsa-miR-223	CLIP-seq
MIRT1412506	hsa-miR-3141	CLIP-seq
MIRT1412507	hsa-miR-324-3p	CLIP-seq
MIRT1412508	hsa-miR-361-5p	CLIP-seq
MIRT1412509	hsa-miR-3619-5p	CLIP-seq
MIRT1412510	hsa-miR-3960	CLIP-seq
MIRT1412511	hsa-miR-4291	CLIP-seq
MIRT1412512	hsa-miR-4313	CLIP-seq
MIRT1412513	hsa-miR-4328	CLIP-seq
MIRT1412514	hsa-miR-4467	CLIP-seq
MIRT1412515	hsa-miR-4697-3p	CLIP-seq
MIRT1412516	hsa-miR-4786-3p	CLIP-seq
MIRT1412517	hsa-miR-590-5p	CLIP-seq
MIRT1412518	hsa-miR-761	CLIP-seq
MIRT1412519	hsa-miR-922	CLIP-seq
MIRT1412503	hsa-miR-21	CLIP-seq
MIRT1412504	hsa-miR-214	CLIP-seq
MIRT1412506	hsa-miR-3141	CLIP-seq
MIRT1412508	hsa-miR-361-5p	CLIP-seq
MIRT1412509	hsa-miR-3619-5p	CLIP-seq
MIRT1412510	hsa-miR-3960	CLIP-seq
MIRT1412511	hsa-miR-4291	CLIP-seq
MIRT1412514	hsa-miR-4467	CLIP-seq
MIRT1412516	hsa-miR-4786-3p	CLIP-seq
MIRT1412517	hsa-miR-590-5p	CLIP-seq
MIRT1412518	hsa-miR-761	CLIP-seq
MIRT1412519	hsa-miR-922	CLIP-seq
MIRT2123859	hsa-miR-106a	CLIP-seq
MIRT2123860	hsa-miR-106b	CLIP-seq
MIRT2123861	hsa-miR-1254	CLIP-seq
MIRT2123862	hsa-miR-149	CLIP-seq
MIRT2123863	hsa-miR-17	CLIP-seq
MIRT2123864	hsa-miR-1914	CLIP-seq
MIRT2123865	hsa-miR-20a	CLIP-seq
MIRT2123866	hsa-miR-20b	CLIP-seq
MIRT2123867	hsa-miR-298	CLIP-seq
MIRT2123868	hsa-miR-3116	CLIP-seq
MIRT2123869	hsa-miR-3609	CLIP-seq
MIRT2123870	hsa-miR-3944-3p	CLIP-seq
MIRT2123871	hsa-miR-3944-5p	CLIP-seq
MIRT2123872	hsa-miR-4796-3p	CLIP-seq
MIRT2123873	hsa-miR-485-5p	CLIP-seq
MIRT2123874	hsa-miR-515-3p	CLIP-seq
MIRT2123875	hsa-miR-519d	CLIP-seq
MIRT2123876	hsa-miR-519e	CLIP-seq
MIRT2123877	hsa-miR-548ah	CLIP-seq
MIRT2123878	hsa-miR-550a	CLIP-seq
MIRT2123879	hsa-miR-661	CLIP-seq
MIRT2123880	hsa-miR-93	CLIP-seq
MIRT2123859	hsa-miR-106a	CLIP-seq
MIRT2123860	hsa-miR-106b	CLIP-seq
MIRT1412501	hsa-miR-1228	CLIP-seq
MIRT2123861	hsa-miR-1254	CLIP-seq
MIRT2123862	hsa-miR-149	CLIP-seq
MIRT2123863	hsa-miR-17	CLIP-seq
MIRT1412502	hsa-miR-1913	CLIP-seq
MIRT2123865	hsa-miR-20a	CLIP-seq
MIRT2123866	hsa-miR-20b	CLIP-seq
MIRT1412503	hsa-miR-21	CLIP-seq
MIRT1412504	hsa-miR-214	CLIP-seq
MIRT2123868	hsa-miR-3116	CLIP-seq
MIRT1412506	hsa-miR-3141	CLIP-seq
MIRT1412507	hsa-miR-324-3p	CLIP-seq
MIRT2123869	hsa-miR-3609	CLIP-seq
MIRT1412508	hsa-miR-361-5p	CLIP-seq
MIRT1412509	hsa-miR-3619-5p	CLIP-seq
MIRT2345906	hsa-miR-3665	CLIP-seq
MIRT2345907	hsa-miR-3934	CLIP-seq
MIRT2123870	hsa-miR-3944-3p	CLIP-seq
MIRT1412510	hsa-miR-3960	CLIP-seq
MIRT1412511	hsa-miR-4291	CLIP-seq
MIRT1412512	hsa-miR-4313	CLIP-seq
MIRT1412514	hsa-miR-4467	CLIP-seq
MIRT1412516	hsa-miR-4786-3p	CLIP-seq
MIRT2123872	hsa-miR-4796-3p	CLIP-seq
MIRT2123875	hsa-miR-519d	CLIP-seq
MIRT2123877	hsa-miR-548ah	CLIP-seq
MIRT2123878	hsa-miR-550a	CLIP-seq
MIRT1412517	hsa-miR-590-5p	CLIP-seq
MIRT2123879	hsa-miR-661	CLIP-seq
MIRT1412518	hsa-miR-761	CLIP-seq
MIRT1412519	hsa-miR-922	CLIP-seq
MIRT2123880	hsa-miR-93	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 22354992, 22854040
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005776	Component	Autophagosome	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	17562788
GO:0006914	Process	Autophagy	IEA
GO:0015031	Process	Protein transport	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0042147	Process	Retrograde transport, endosome to Golgi	IBA
GO:0042147	Process	Retrograde transport, endosome to Golgi	IMP	17562788
GO:0055037	Component	Recycling endosome	IEA
GO:0055037	Component	Recycling endosome	TAS
GO:1902017	Process	Regulation of cilium assembly	IMP	17646400

MIM	HGNC	e!Ensembl
616659	25699	ENSG00000104946

Q9HA65

Protein name

TBC1 domain family member 17

Protein function

Probable RAB GTPase-activating protein that inhibits RAB8A/B function. Reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC) and inhibits Rab8-mediated endocytic trafficking, such as that of transferrin rec

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00566	RabGAP-TBC	313 → 542	Rab-GTPase-TBC domain	Family
PF12068	PH_RBD	7 → 205	Rab-binding domain (RBD)	Domain

Sequence

MEGAGYRVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQI
LFSKKDSSGGDSCASEEEPTFDPDYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFS
VSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQD
SRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQP
QPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVP
ELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPE
QERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGM
SDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDF
LDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDT
LMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEP
HSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDSSLEILPEEEDEGADS

Sequence length

648

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Mitophagy - animal	TBC/RABGAPs

TBC1D17 (TBC1 domain family member 17)

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