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Gene Gene information from NCBI Gene database.
Entrez ID 6432
Gene name Serine and arginine rich splicing factor 7
Gene symbol SRSF7
Synonyms (NCBI Gene)
9G8AAG3SFRS7
Chromosome 2
Chromosome location 2p22.1
Summary The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an N-terminal RNA recognition motif (RRM) for binding RNA and a C-t
miRNA miRNA information provided by mirtarbase database.
605 Show/Hide all (605)
miRTarBase ID miRNA Experiments Reference
MIRT016062 hsa-miR-374b-5p Sequencing 20371350
MIRT016101 hsa-miR-421 Sequencing 20371350
MIRT020279 hsa-miR-130b-3p Sequencing 20371350
MIRT023916 hsa-miR-1-3p Proteomics 18668040
MIRT025199 hsa-miR-181a-5p Sequencing 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23 Show/Hide all (23)
GO ID Ontology Definition Evidence Reference
GO:0000381 Process Regulation of alternative mRNA splicing, via spliceosome IBA
GO:0003676 Function Nucleic acid binding IEA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IEA
GO:0003729 Function MRNA binding IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
600572 10789 ENSG00000115875
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q16629
Protein name Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Protein function Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be
PDB 2HVZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00076 RRM_1 13 → 78 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
Tissue specificity TISSUE SPECIFICITY: Brain, liver, kidney and lung.
Sequence
MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDA
EDAVRGLDGKVICGSRVR
VELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCH
RYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSR
SGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPERMD
Sequence length 238
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Spliceosome Transport of Mature mRNA derived from an Intron-Containing Transcript
Amyotrophic lateral sclerosis mRNA Splicing - Major Pathway
Herpes simplex virus 1 infection mRNA Splicing - Minor Pathway
  mRNA 3'-end processing
  RNA Polymerase II Transcription Termination