SLU7 (spliceosome associated SLU7)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10569 |
| Gene name | Spliceosome associated SLU7 |
| Gene symbol | SLU7 |
| Synonyms (NCBI Gene) |
9G8hSlu7
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| Chromosome | 5 |
| Chromosome location | 5q33.3 |
| Summary | Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the splic |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O95391 | ||||||||||
| Protein name | Pre-mRNA-splicing factor SLU7 (hSlu7) | ||||||||||
| Protein function | Required for pre-mRNA splicing as component of the spliceosome (PubMed:10197984, PubMed:28502770, PubMed:30705154). Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site | ||||||||||
| PDB | 5XJC , 6ICZ , 6QDV , 7W5A , 7W5B , 8C6J , 9FMD | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MSATVVDAVNAAPLSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDIN |
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| Sequence length | 586 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with SLU7 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to SLU7 (see Related Genes above), that are NOT already directly curated for SLU7 itself -- a lead worth checking, not a confirmed association.
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