Gene ontology (GO)Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
Neutral amino acid transporter 9 (Solute carrier family 38 member 9) (Up-regulated in lung cancer 11)
Protein function
Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels (PubMed:25561175, PubMed:25567906, PubMed:29053970). Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 compl
Evidence Score:★☆☆☆☆ Gene-disease association found in Text Mining only★★☆☆☆ Found in Text Mining and Unknown/Other Associations★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations
ClinVar entries with uncertain/conflicting evidence, and associations from other databases
(OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
["mTOR signaling pathway","TP53 Regulates Metabolic Genes","Macroautophagy","Regulation of PTEN gene transcription","Amino acids regulate mTORC1","mTOR signalling","mTORC1-mediated signalling","Energy dependent regulation of mTOR by LKB1-AMPK"]
0
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Diseases Linked via Similar GenesDiseases curated for genes most similar to SLC38A9 (see Related Genes above), that are NOT already directly curated for SLC38A9 itself -- a lead worth checking, not a confirmed association.