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Gene Gene information from NCBI Gene database.
Entrez ID 51100
Gene name SH3 domain containing GRB2 like, endophilin B1
Gene symbol SH3GLB1
Synonyms (NCBI Gene)
Bif-1CGI-61PPP1R70dJ612B15.2
Chromosome 1
Chromosome location 1p22.3
Summary This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may
miRNA miRNA information provided by mirtarbase database.
706 Show/Hide all (706)
miRTarBase ID miRNA Experiments Reference
MIRT020362 hsa-miR-29c-3p Sequencing 20371350
MIRT028134 hsa-miR-93-5p Sequencing 20371350
MIRT032399 hsa-let-7b-5p Proteomics 18668040
MIRT448480 hsa-miR-3646 HITS-CLIP 19536157
MIRT710012 hsa-miR-3168 HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
51 Show/Hide all (51)
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0000421 Component Autophagosome membrane IDA 17891140
GO:0000421 Component Autophagosome membrane IEA
GO:0005504 Function Fatty acid binding IEA
GO:0005515 Function Protein binding IPI 11161816, 17891140, 19074440, 20562859, 21988832, 23414517, 24056303, 25416956, 25910212, 27107012, 31515488, 32296183, 32814053, 33961781, 35271311
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609287 10833 ENSG00000097033
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y371
Protein name Endophilin-B1 (Bax-interacting factor 1) (Bif-1) (SH3 domain-containing GRB2-like protein B1)
Protein function May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144). Required for coatomer-mediated retrograde transport in certain cells (By similarity). May recruit other proteins to membranes with high curvature. May promote me
PDB 6UP6 , 6UPN , 9G2R , 9G2U , 9G2W
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03114 BAR 9 → 254 BAR domain Domain
PF14604 SH3_9 312 → 362 Variant SH3 domain Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:11161816, ECO:0000269|PubMed:1
Sequence
Sequence length 365
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway
Autophagy - animal
Endocytosis