SEC22B (SEC22 homolog B, vesicle trafficking protein)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 9554
• Gene name: SEC22 homolog B, vesicle trafficking protein
• Gene symbol: SEC22B
• Synonyms (NCBI Gene): ERS-24, SEC22L1
• Chromosome: 1
• Chromosome location: 1p12
• Summary: The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and C

miRNA Show/Hide all (351)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1332563	hsa-miR-1200	CLIP-seq
MIRT1332564	hsa-miR-1243	CLIP-seq
MIRT1332565	hsa-miR-1248	CLIP-seq
MIRT1332566	hsa-miR-1252	CLIP-seq
MIRT1332567	hsa-miR-1265	CLIP-seq
MIRT1332568	hsa-miR-1271	CLIP-seq
MIRT1332569	hsa-miR-1289	CLIP-seq
MIRT1332570	hsa-miR-1303	CLIP-seq
MIRT1332571	hsa-miR-134	CLIP-seq
MIRT1332572	hsa-miR-135a	CLIP-seq
MIRT1332573	hsa-miR-135b	CLIP-seq
MIRT1332574	hsa-miR-136	CLIP-seq
MIRT1332575	hsa-miR-139-5p	CLIP-seq
MIRT1332576	hsa-miR-1825	CLIP-seq
MIRT1332577	hsa-miR-1827	CLIP-seq
MIRT1332578	hsa-miR-1912	CLIP-seq
MIRT1332579	hsa-miR-19a	CLIP-seq
MIRT1332580	hsa-miR-19b	CLIP-seq
MIRT1332581	hsa-miR-216a	CLIP-seq
MIRT1332582	hsa-miR-23a	CLIP-seq
MIRT1332583	hsa-miR-23b	CLIP-seq
MIRT1332584	hsa-miR-23c	CLIP-seq
MIRT1332585	hsa-miR-296-3p	CLIP-seq
MIRT1332586	hsa-miR-298	CLIP-seq
MIRT1332587	hsa-miR-3074-5p	CLIP-seq
MIRT1332588	hsa-miR-31	CLIP-seq
MIRT1332589	hsa-miR-3118	CLIP-seq
MIRT1332590	hsa-miR-3120-3p	CLIP-seq
MIRT1332591	hsa-miR-3123	CLIP-seq
MIRT1332592	hsa-miR-3125	CLIP-seq
MIRT1332593	hsa-miR-3140-5p	CLIP-seq
MIRT1332594	hsa-miR-3148	CLIP-seq
MIRT1332595	hsa-miR-3152-3p	CLIP-seq
MIRT1332596	hsa-miR-3156-5p	CLIP-seq
MIRT1332597	hsa-miR-3173-3p	CLIP-seq
MIRT1332598	hsa-miR-3189-5p	CLIP-seq
MIRT1332599	hsa-miR-3192	CLIP-seq
MIRT1332600	hsa-miR-3198	CLIP-seq
MIRT1332601	hsa-miR-337-3p	CLIP-seq
MIRT1332602	hsa-miR-3605-5p	CLIP-seq
MIRT1332603	hsa-miR-3614-5p	CLIP-seq
MIRT1332604	hsa-miR-3618	CLIP-seq
MIRT1332605	hsa-miR-3646	CLIP-seq
MIRT1332606	hsa-miR-3647-3p	CLIP-seq
MIRT1332607	hsa-miR-365	CLIP-seq
MIRT1332608	hsa-miR-3654	CLIP-seq
MIRT1332609	hsa-miR-3662	CLIP-seq
MIRT1332610	hsa-miR-3670	CLIP-seq
MIRT1332611	hsa-miR-3688-5p	CLIP-seq
MIRT1332612	hsa-miR-3689a-3p	CLIP-seq
MIRT1332613	hsa-miR-3689c	CLIP-seq
MIRT1332614	hsa-miR-374c	CLIP-seq
MIRT1332615	hsa-miR-376c	CLIP-seq
MIRT1332616	hsa-miR-3910	CLIP-seq
MIRT1332617	hsa-miR-3916	CLIP-seq
MIRT1332618	hsa-miR-3919	CLIP-seq
MIRT1332619	hsa-miR-3922-5p	CLIP-seq
MIRT1332620	hsa-miR-3938	CLIP-seq
MIRT1332621	hsa-miR-3942-3p	CLIP-seq
MIRT1332622	hsa-miR-409-3p	CLIP-seq
MIRT1332623	hsa-miR-4287	CLIP-seq
MIRT1332624	hsa-miR-4294	CLIP-seq
MIRT1332625	hsa-miR-4309	CLIP-seq
MIRT1332626	hsa-miR-4320	CLIP-seq
MIRT1332627	hsa-miR-4328	CLIP-seq
MIRT1332628	hsa-miR-4422	CLIP-seq
MIRT1332629	hsa-miR-4428	CLIP-seq
MIRT1332630	hsa-miR-4436b-5p	CLIP-seq
MIRT1332631	hsa-miR-4469	CLIP-seq
MIRT1332632	hsa-miR-4474-3p	CLIP-seq
MIRT1332633	hsa-miR-4528	CLIP-seq
MIRT1332634	hsa-miR-4643	CLIP-seq
MIRT1332635	hsa-miR-466	CLIP-seq
MIRT1332636	hsa-miR-4668-5p	CLIP-seq
MIRT1332637	hsa-miR-4676-5p	CLIP-seq
MIRT1332638	hsa-miR-4677-3p	CLIP-seq
MIRT1332639	hsa-miR-4679	CLIP-seq
MIRT1332640	hsa-miR-4685-3p	CLIP-seq
MIRT1332641	hsa-miR-4708-3p	CLIP-seq
MIRT1332642	hsa-miR-4712-3p	CLIP-seq
MIRT1332643	hsa-miR-4713-5p	CLIP-seq
MIRT1332644	hsa-miR-4728-5p	CLIP-seq
MIRT1332645	hsa-miR-4742-3p	CLIP-seq
MIRT1332646	hsa-miR-4753-3p	CLIP-seq
MIRT1332647	hsa-miR-4753-5p	CLIP-seq
MIRT1332648	hsa-miR-4756-3p	CLIP-seq
MIRT1332649	hsa-miR-4757-5p	CLIP-seq
MIRT1332650	hsa-miR-4758-3p	CLIP-seq
MIRT1332651	hsa-miR-4760-3p	CLIP-seq
MIRT1332652	hsa-miR-4766-3p	CLIP-seq
MIRT1332653	hsa-miR-4789-3p	CLIP-seq
MIRT1332654	hsa-miR-4789-5p	CLIP-seq
MIRT1332655	hsa-miR-494	CLIP-seq
MIRT1332656	hsa-miR-498	CLIP-seq
MIRT1332657	hsa-miR-512-3p	CLIP-seq
MIRT1332658	hsa-miR-548p	CLIP-seq
MIRT1332659	hsa-miR-563	CLIP-seq
MIRT1332660	hsa-miR-575	CLIP-seq
MIRT1332661	hsa-miR-576-5p	CLIP-seq
MIRT1332662	hsa-miR-578	CLIP-seq
MIRT1332663	hsa-miR-580	CLIP-seq
MIRT1332664	hsa-miR-621	CLIP-seq
MIRT1332665	hsa-miR-630	CLIP-seq
MIRT1332666	hsa-miR-655	CLIP-seq
MIRT1332667	hsa-miR-664	CLIP-seq
MIRT1332668	hsa-miR-676	CLIP-seq
MIRT1332669	hsa-miR-877	CLIP-seq
MIRT1332670	hsa-miR-889	CLIP-seq
MIRT1332671	hsa-miR-890	CLIP-seq
MIRT1332672	hsa-miR-924	CLIP-seq
MIRT1332673	hsa-miR-934	CLIP-seq
MIRT1332674	hsa-miR-943	CLIP-seq
MIRT1332675	hsa-miR-96	CLIP-seq
MIRT2098379	hsa-miR-1	CLIP-seq
MIRT1332563	hsa-miR-1200	CLIP-seq
MIRT1332567	hsa-miR-1265	CLIP-seq
MIRT2098380	hsa-miR-1286	CLIP-seq
MIRT1332570	hsa-miR-1303	CLIP-seq
MIRT1332571	hsa-miR-134	CLIP-seq
MIRT1332575	hsa-miR-139-5p	CLIP-seq
MIRT1332578	hsa-miR-1912	CLIP-seq
MIRT2098381	hsa-miR-1913	CLIP-seq
MIRT2098382	hsa-miR-206	CLIP-seq
MIRT1332581	hsa-miR-216a	CLIP-seq
MIRT2098383	hsa-miR-3065-5p	CLIP-seq
MIRT1332587	hsa-miR-3074-5p	CLIP-seq
MIRT1332588	hsa-miR-31	CLIP-seq
MIRT1332589	hsa-miR-3118	CLIP-seq
MIRT1332591	hsa-miR-3123	CLIP-seq
MIRT1332592	hsa-miR-3125	CLIP-seq
MIRT1332593	hsa-miR-3140-5p	CLIP-seq
MIRT1332595	hsa-miR-3152-3p	CLIP-seq
MIRT2098384	hsa-miR-324-3p	CLIP-seq
MIRT1332602	hsa-miR-3605-5p	CLIP-seq
MIRT1332604	hsa-miR-3618	CLIP-seq
MIRT1332606	hsa-miR-3647-3p	CLIP-seq
MIRT1332610	hsa-miR-3670	CLIP-seq
MIRT1332611	hsa-miR-3688-5p	CLIP-seq
MIRT1332615	hsa-miR-376c	CLIP-seq
MIRT1332617	hsa-miR-3916	CLIP-seq
MIRT1332618	hsa-miR-3919	CLIP-seq
MIRT1332622	hsa-miR-409-3p	CLIP-seq
MIRT1332623	hsa-miR-4287	CLIP-seq
MIRT2098385	hsa-miR-4311	CLIP-seq
MIRT2098386	hsa-miR-4313	CLIP-seq
MIRT1332627	hsa-miR-4328	CLIP-seq
MIRT1332631	hsa-miR-4469	CLIP-seq
MIRT1332632	hsa-miR-4474-3p	CLIP-seq
MIRT1332633	hsa-miR-4528	CLIP-seq
MIRT1332640	hsa-miR-4685-3p	CLIP-seq
MIRT1332641	hsa-miR-4708-3p	CLIP-seq
MIRT1332643	hsa-miR-4713-5p	CLIP-seq
MIRT2098387	hsa-miR-4719	CLIP-seq
MIRT2098388	hsa-miR-4722-5p	CLIP-seq
MIRT2098389	hsa-miR-4724-5p	CLIP-seq
MIRT1332645	hsa-miR-4742-3p	CLIP-seq
MIRT1332646	hsa-miR-4753-3p	CLIP-seq
MIRT1332648	hsa-miR-4756-3p	CLIP-seq
MIRT1332652	hsa-miR-4766-3p	CLIP-seq
MIRT1332654	hsa-miR-4789-5p	CLIP-seq
MIRT2098390	hsa-miR-490-3p	CLIP-seq
MIRT1332658	hsa-miR-548p	CLIP-seq
MIRT1332659	hsa-miR-563	CLIP-seq
MIRT1332662	hsa-miR-578	CLIP-seq
MIRT1332663	hsa-miR-580	CLIP-seq
MIRT2098391	hsa-miR-595	CLIP-seq
MIRT2098392	hsa-miR-613	CLIP-seq
MIRT1332665	hsa-miR-630	CLIP-seq
MIRT2098393	hsa-miR-649	CLIP-seq
MIRT1332667	hsa-miR-664	CLIP-seq
MIRT1332668	hsa-miR-676	CLIP-seq
MIRT1332669	hsa-miR-877	CLIP-seq
MIRT1332673	hsa-miR-934	CLIP-seq
MIRT1332674	hsa-miR-943	CLIP-seq
MIRT1332564	hsa-miR-1243	CLIP-seq
MIRT1332571	hsa-miR-134	CLIP-seq
MIRT1332575	hsa-miR-139-5p	CLIP-seq
MIRT1332582	hsa-miR-23a	CLIP-seq
MIRT1332583	hsa-miR-23b	CLIP-seq
MIRT1332584	hsa-miR-23c	CLIP-seq
MIRT1332589	hsa-miR-3118	CLIP-seq
MIRT1332590	hsa-miR-3120-3p	CLIP-seq
MIRT1332596	hsa-miR-3156-5p	CLIP-seq
MIRT1332608	hsa-miR-3654	CLIP-seq
MIRT1332623	hsa-miR-4287	CLIP-seq
MIRT1332631	hsa-miR-4469	CLIP-seq
MIRT1332633	hsa-miR-4528	CLIP-seq
MIRT1332640	hsa-miR-4685-3p	CLIP-seq
MIRT1332643	hsa-miR-4713-5p	CLIP-seq
MIRT2098388	hsa-miR-4722-5p	CLIP-seq
MIRT1332645	hsa-miR-4742-3p	CLIP-seq
MIRT1332663	hsa-miR-580	CLIP-seq
MIRT1332665	hsa-miR-630	CLIP-seq
MIRT1332667	hsa-miR-664	CLIP-seq
MIRT1332674	hsa-miR-943	CLIP-seq
MIRT1332567	hsa-miR-1265	CLIP-seq
MIRT1332575	hsa-miR-139-5p	CLIP-seq
MIRT2394157	hsa-miR-3201	CLIP-seq
MIRT1332602	hsa-miR-3605-5p	CLIP-seq
MIRT1332604	hsa-miR-3618	CLIP-seq
MIRT2394158	hsa-miR-4700-3p	CLIP-seq
MIRT2394159	hsa-miR-4738-3p	CLIP-seq
MIRT2394160	hsa-miR-4791	CLIP-seq
MIRT2394161	hsa-miR-495	CLIP-seq
MIRT1332673	hsa-miR-934	CLIP-seq
MIRT2459029	hsa-miR-4436a	CLIP-seq
MIRT1332641	hsa-miR-4708-3p	CLIP-seq
MIRT1332646	hsa-miR-4753-3p	CLIP-seq
MIRT1332662	hsa-miR-578	CLIP-seq
MIRT2098379	hsa-miR-1	CLIP-seq
MIRT1332564	hsa-miR-1243	CLIP-seq
MIRT1332565	hsa-miR-1248	CLIP-seq
MIRT1332566	hsa-miR-1252	CLIP-seq
MIRT2618944	hsa-miR-1264	CLIP-seq
MIRT2098380	hsa-miR-1286	CLIP-seq
MIRT2618945	hsa-miR-1288	CLIP-seq
MIRT1332569	hsa-miR-1289	CLIP-seq
MIRT1332575	hsa-miR-139-5p	CLIP-seq
MIRT1332578	hsa-miR-1912	CLIP-seq
MIRT2098381	hsa-miR-1913	CLIP-seq
MIRT1332579	hsa-miR-19a	CLIP-seq
MIRT1332580	hsa-miR-19b	CLIP-seq
MIRT2098382	hsa-miR-206	CLIP-seq
MIRT1332581	hsa-miR-216a	CLIP-seq
MIRT1332582	hsa-miR-23a	CLIP-seq
MIRT1332583	hsa-miR-23b	CLIP-seq
MIRT1332584	hsa-miR-23c	CLIP-seq
MIRT2098383	hsa-miR-3065-5p	CLIP-seq
MIRT1332588	hsa-miR-31	CLIP-seq
MIRT1332590	hsa-miR-3120-3p	CLIP-seq
MIRT1332591	hsa-miR-3123	CLIP-seq
MIRT1332592	hsa-miR-3125	CLIP-seq
MIRT2618946	hsa-miR-3129-3p	CLIP-seq
MIRT1332595	hsa-miR-3152-3p	CLIP-seq
MIRT1332596	hsa-miR-3156-5p	CLIP-seq
MIRT2618947	hsa-miR-3163	CLIP-seq
MIRT2618948	hsa-miR-3169	CLIP-seq
MIRT1332597	hsa-miR-3173-3p	CLIP-seq
MIRT1332600	hsa-miR-3198	CLIP-seq
MIRT2098384	hsa-miR-324-3p	CLIP-seq
MIRT2618949	hsa-miR-340	CLIP-seq
MIRT2618950	hsa-miR-3613-3p	CLIP-seq
MIRT1332605	hsa-miR-3646	CLIP-seq
MIRT1332606	hsa-miR-3647-3p	CLIP-seq
MIRT1332608	hsa-miR-3654	CLIP-seq
MIRT1332611	hsa-miR-3688-5p	CLIP-seq
MIRT1332616	hsa-miR-3910	CLIP-seq
MIRT1332617	hsa-miR-3916	CLIP-seq
MIRT1332618	hsa-miR-3919	CLIP-seq
MIRT1332619	hsa-miR-3922-5p	CLIP-seq
MIRT1332621	hsa-miR-3942-3p	CLIP-seq
MIRT1332622	hsa-miR-409-3p	CLIP-seq
MIRT2618951	hsa-miR-4282	CLIP-seq
MIRT1332624	hsa-miR-4294	CLIP-seq
MIRT2618952	hsa-miR-4297	CLIP-seq
MIRT1332625	hsa-miR-4309	CLIP-seq
MIRT2098385	hsa-miR-4311	CLIP-seq
MIRT2098386	hsa-miR-4313	CLIP-seq
MIRT2618953	hsa-miR-4330	CLIP-seq
MIRT1332628	hsa-miR-4422	CLIP-seq
MIRT1332629	hsa-miR-4428	CLIP-seq
MIRT1332632	hsa-miR-4474-3p	CLIP-seq
MIRT2618954	hsa-miR-4477b	CLIP-seq
MIRT2618955	hsa-miR-4529-5p	CLIP-seq
MIRT1332642	hsa-miR-4712-3p	CLIP-seq
MIRT2098387	hsa-miR-4719	CLIP-seq
MIRT2098388	hsa-miR-4722-5p	CLIP-seq
MIRT2618956	hsa-miR-4735-5p	CLIP-seq
MIRT2394159	hsa-miR-4738-3p	CLIP-seq
MIRT1332647	hsa-miR-4753-5p	CLIP-seq
MIRT1332648	hsa-miR-4756-3p	CLIP-seq
MIRT1332651	hsa-miR-4760-3p	CLIP-seq
MIRT1332652	hsa-miR-4766-3p	CLIP-seq
MIRT1332655	hsa-miR-494	CLIP-seq
MIRT2394161	hsa-miR-495	CLIP-seq
MIRT1332656	hsa-miR-498	CLIP-seq
MIRT2618957	hsa-miR-548ae	CLIP-seq
MIRT2618958	hsa-miR-548aj	CLIP-seq
MIRT2618959	hsa-miR-548am	CLIP-seq
MIRT1332658	hsa-miR-548p	CLIP-seq
MIRT2618960	hsa-miR-548x	CLIP-seq
MIRT1332659	hsa-miR-563	CLIP-seq
MIRT2618961	hsa-miR-570	CLIP-seq
MIRT2098391	hsa-miR-595	CLIP-seq
MIRT2618962	hsa-miR-606	CLIP-seq
MIRT2098392	hsa-miR-613	CLIP-seq
MIRT1332664	hsa-miR-621	CLIP-seq
MIRT1332670	hsa-miR-889	CLIP-seq
MIRT1332672	hsa-miR-924	CLIP-seq
MIRT2098379	hsa-miR-1	CLIP-seq
MIRT1332564	hsa-miR-1243	CLIP-seq
MIRT2618944	hsa-miR-1264	CLIP-seq
MIRT2098380	hsa-miR-1286	CLIP-seq
MIRT1332569	hsa-miR-1289	CLIP-seq
MIRT1332575	hsa-miR-139-5p	CLIP-seq
MIRT1332578	hsa-miR-1912	CLIP-seq
MIRT2098381	hsa-miR-1913	CLIP-seq
MIRT1332579	hsa-miR-19a	CLIP-seq
MIRT1332580	hsa-miR-19b	CLIP-seq
MIRT2098382	hsa-miR-206	CLIP-seq
MIRT1332582	hsa-miR-23a	CLIP-seq
MIRT1332583	hsa-miR-23b	CLIP-seq
MIRT1332584	hsa-miR-23c	CLIP-seq
MIRT2098383	hsa-miR-3065-5p	CLIP-seq
MIRT1332588	hsa-miR-31	CLIP-seq
MIRT1332590	hsa-miR-3120-3p	CLIP-seq
MIRT1332592	hsa-miR-3125	CLIP-seq
MIRT2618946	hsa-miR-3129-3p	CLIP-seq
MIRT1332595	hsa-miR-3152-3p	CLIP-seq
MIRT1332596	hsa-miR-3156-5p	CLIP-seq
MIRT2618947	hsa-miR-3163	CLIP-seq
MIRT1332597	hsa-miR-3173-3p	CLIP-seq
MIRT1332600	hsa-miR-3198	CLIP-seq
MIRT2098384	hsa-miR-324-3p	CLIP-seq
MIRT2618949	hsa-miR-340	CLIP-seq
MIRT2618950	hsa-miR-3613-3p	CLIP-seq
MIRT1332605	hsa-miR-3646	CLIP-seq
MIRT1332606	hsa-miR-3647-3p	CLIP-seq
MIRT1332608	hsa-miR-3654	CLIP-seq
MIRT1332611	hsa-miR-3688-5p	CLIP-seq
MIRT1332617	hsa-miR-3916	CLIP-seq
MIRT1332618	hsa-miR-3919	CLIP-seq
MIRT1332622	hsa-miR-409-3p	CLIP-seq
MIRT2618951	hsa-miR-4282	CLIP-seq
MIRT1332624	hsa-miR-4294	CLIP-seq
MIRT1332625	hsa-miR-4309	CLIP-seq
MIRT2098385	hsa-miR-4311	CLIP-seq
MIRT2098386	hsa-miR-4313	CLIP-seq
MIRT1332628	hsa-miR-4422	CLIP-seq
MIRT1332629	hsa-miR-4428	CLIP-seq
MIRT1332632	hsa-miR-4474-3p	CLIP-seq
MIRT2618954	hsa-miR-4477b	CLIP-seq
MIRT2618955	hsa-miR-4529-5p	CLIP-seq
MIRT1332642	hsa-miR-4712-3p	CLIP-seq
MIRT2098388	hsa-miR-4722-5p	CLIP-seq
MIRT2618956	hsa-miR-4735-5p	CLIP-seq
MIRT2394159	hsa-miR-4738-3p	CLIP-seq
MIRT1332647	hsa-miR-4753-5p	CLIP-seq
MIRT1332652	hsa-miR-4766-3p	CLIP-seq
MIRT1332655	hsa-miR-494	CLIP-seq
MIRT2394161	hsa-miR-495	CLIP-seq
MIRT2618957	hsa-miR-548ae	CLIP-seq
MIRT2618958	hsa-miR-548aj	CLIP-seq
MIRT2618959	hsa-miR-548am	CLIP-seq
MIRT1332658	hsa-miR-548p	CLIP-seq
MIRT2618960	hsa-miR-548x	CLIP-seq
MIRT2618961	hsa-miR-570	CLIP-seq
MIRT2098391	hsa-miR-595	CLIP-seq
MIRT2618962	hsa-miR-606	CLIP-seq
MIRT2098392	hsa-miR-613	CLIP-seq
MIRT1332672	hsa-miR-924	CLIP-seq

Gene ontology (GO) Show/Hide all (28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0005484	Function	SNAP receptor activity	IEA
GO:0005515	Function	Protein binding	IPI	15272311, 16354670, 17499046, 19369418, 22153078, 28514442, 32296183, 33961781, 34779586, 35271311
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IDA	15308636
GO:0005794	Component	Golgi apparatus	IEA
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IEA
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	TAS	9094723
GO:0006890	Process	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IEA
GO:0012505	Component	Endomembrane system	IEA
GO:0012507	Component	ER to Golgi transport vesicle membrane	IDA	17499046
GO:0012507	Component	ER to Golgi transport vesicle membrane	TAS
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0030133	Component	Transport vesicle	TAS
GO:0030670	Component	Phagocytic vesicle membrane	TAS
GO:0033116	Component	Endoplasmic reticulum-Golgi intermediate compartment membrane	IEA
GO:0033116	Component	Endoplasmic reticulum-Golgi intermediate compartment membrane	TAS
GO:0042470	Component	Melanosome	IEA
GO:0045732	Process	Positive regulation of protein catabolic process	IMP	21242315
GO:0061025	Process	Membrane fusion	IEA
GO:1902902	Process	Negative regulation of autophagosome assembly	IMP	21242315

Other IDs

• MIM: 604029
• HGNC: 10700
• e!Ensembl: ENSG00000265808

Protein

• UniProt ID: O75396
• Protein name: Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
• Protein function: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
• PDB: 2NUP , 2NUT , 3EGD , 3EGX , 8HR0
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00957	Synaptobrevin	131 → 215	Synaptobrevin	Family
  PF13774	Longin	37 → 117	Regulated-SNARE-like domain	Domain

• Sequence:

  MVLLTMIARVADGLPLAASMQEDEQSGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGAMT
  FHYIIEQGVCDLVLCEAAFPKTLAFAYLEDLHSEFDEQHGKKVPTVSRPYSFIEFDTFIQ
  KTKKLYIDSCARRNLGSINTELQDVQRIMVANIEEVLQRGEALSALDSKANNLSSLSKKY
  RQDAKYLNMHSTYAKLAAVAVFFIMLIVYVRFWWL

• Sequence length: 215

Pathways

KEGG Pathway	Reactome Pathway
SNARE interactions in vesicular transport	ER-Phagosome pathway
Phagosome	COPII-mediated vesicle transport
Legionellosis	Cargo concentration in the ER
	COPI-dependent Golgi-to-ER retrograde traffic

Related Genes

Sort by: Blended Diseases Pathways Evidence source

STX18 3 shared pathwaysSNARE interactions in vesicular transport, Phagosome, COPI-dependent Golgi-to-ER retrograde traffic Related via 3 shared pathways including SNARE interactions in vesicular transport, Phagosome. TMED2 3 shared pathwaysCOPI-dependent Golgi-to-ER retrograde traffic, COPII-mediated vesicle transport, Cargo concentration in the ER Related via 3 shared pathways including COPI-dependent Golgi-to-ER retrograde traffic, COPII-mediated vesicle transport. TMED10 3 shared pathwaysCOPI-dependent Golgi-to-ER retrograde traffic, COPII-mediated vesicle transport, Cargo concentration in the ER Related via 3 shared pathways including COPI-dependent Golgi-to-ER retrograde traffic, COPII-mediated vesicle transport. STX5 3 shared pathwaysSNARE interactions in vesicular transport, COPII-mediated vesicle transport, Cargo concentration in the ER Related via 3 shared pathways including SNARE interactions in vesicular transport, COPII-mediated vesicle transport. VAMP3 3 shared pathwaysSNARE interactions in vesicular transport, Phagosome, ER-Phagosome pathway Related via 3 shared pathways including SNARE interactions in vesicular transport, Phagosome.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
STX18	0	[]	3	["SNARE interactions in vesicular transport","Phagosome","COPI-dependent Golgi-to-ER retrograde traffic"]	0	[]
TMED2	0	[]	3	["COPI-dependent Golgi-to-ER retrograde traffic","COPII-mediated vesicle transport","Cargo concentration in the ER"]	0	[]
TMED10	0	[]	3	["COPI-dependent Golgi-to-ER retrograde traffic","COPII-mediated vesicle transport","Cargo concentration in the ER"]	0	[]
STX5	0	[]	3	["SNARE interactions in vesicular transport","COPII-mediated vesicle transport","Cargo concentration in the ER"]	0	[]
VAMP3	0	[]	3	["SNARE interactions in vesicular transport","Phagosome","ER-Phagosome pathway"]	0	[]

Diseases Linked via Similar Genes

Scoliosis Linked via 1 of 5 related genesSTX18 Myocardial ischemia Linked via 1 of 5 related genesTMED2 Alzheimer disease Linked via 1 of 5 related genesTMED10 Coronary artery disease Linked via 1 of 5 related genesTMED10 Prostate cancer Linked via 1 of 5 related genesTMED10

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Scoliosis	1	["STX18"]
Myocardial ischemia	1	["TMED2"]
Alzheimer disease	1	["TMED10"]
Coronary artery disease	1	["TMED10"]
Prostate cancer	1	["TMED10"]