Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	6217
Gene name	Ribosomal protein S16
Gene symbol	RPS16
Synonyms (NCBI Gene)	S16uS9
Chromosome	19
Chromosome location	19q13.2
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro

119 Show/Hide all (119)

miRTarBase ID	miRNA	Experiments	Reference
MIRT050772	hsa-miR-17-3p	CLASH	23622248
MIRT050371	hsa-miR-24-3p	CLASH	23622248
MIRT045423	hsa-miR-149-5p	CLASH	23622248
MIRT044589	hsa-miR-320a	CLASH	23622248
MIRT039569	hsa-miR-652-3p	CLASH	23622248
MIRT036088	hsa-miR-1296-5p	CLASH	23622248
MIRT036088	hsa-miR-1296-5p	CLASH	23622248
MIRT035883	hsa-miR-1303	CLASH	23622248
MIRT574496	hsa-miR-3167	PAR-CLIP	20371350
MIRT574494	hsa-miR-876-5p	PAR-CLIP	20371350
MIRT574493	hsa-miR-3159	PAR-CLIP	20371350
MIRT574492	hsa-miR-4490	PAR-CLIP	20371350
MIRT574491	hsa-miR-4774-5p	PAR-CLIP	20371350
MIRT574490	hsa-miR-27a-5p	PAR-CLIP	20371350
MIRT574489	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT574488	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT574487	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT574486	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT574485	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT574484	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT574483	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT574482	hsa-miR-548a-3p	PAR-CLIP	20371350
MIRT574481	hsa-miR-548ar-3p	PAR-CLIP	20371350
MIRT574480	hsa-miR-548az-3p	PAR-CLIP	20371350
MIRT574479	hsa-miR-548e-3p	PAR-CLIP	20371350
MIRT574478	hsa-miR-548f-3p	PAR-CLIP	20371350
MIRT574477	hsa-miR-548g-3p	PAR-CLIP	20371350
MIRT574475	hsa-miR-6882-5p	PAR-CLIP	20371350
MIRT574476	hsa-miR-452-5p	PAR-CLIP	20371350
MIRT574474	hsa-miR-4676-3p	PAR-CLIP	20371350
MIRT574473	hsa-miR-892c-3p	PAR-CLIP	20371350
MIRT574472	hsa-miR-3174	PAR-CLIP	20371350
MIRT574471	hsa-miR-300	PAR-CLIP	20371350
MIRT574470	hsa-miR-381-3p	PAR-CLIP	20371350
MIRT574468	hsa-miR-4666a-3p	PAR-CLIP	20371350
MIRT574469	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT082273	hsa-miR-371b-5p	PAR-CLIP	20371350
MIRT082260	hsa-miR-373-5p	PAR-CLIP	20371350
MIRT082263	hsa-miR-616-5p	PAR-CLIP	20371350
MIRT574467	hsa-miR-5702	PAR-CLIP	20371350
MIRT574466	hsa-miR-2052	PAR-CLIP	20371350
MIRT574465	hsa-let-7a-3p	PAR-CLIP	20371350
MIRT574464	hsa-let-7b-3p	PAR-CLIP	20371350
MIRT574463	hsa-let-7f-1-3p	PAR-CLIP	20371350
MIRT574462	hsa-miR-98-3p	PAR-CLIP	20371350
MIRT574461	hsa-miR-4789-5p	PAR-CLIP	20371350
MIRT574460	hsa-let-7f-2-3p	PAR-CLIP	20371350
MIRT574459	hsa-miR-1185-1-3p	PAR-CLIP	20371350
MIRT574458	hsa-miR-1185-2-3p	PAR-CLIP	20371350
MIRT574457	hsa-miR-4795-3p	PAR-CLIP	20371350
MIRT574456	hsa-miR-937-5p	PAR-CLIP	20371350
MIRT574455	hsa-miR-627-5p	PAR-CLIP	20371350
MIRT574454	hsa-miR-8081	PAR-CLIP	20371350
MIRT574453	hsa-miR-8055	PAR-CLIP	20371350
MIRT574496	hsa-miR-3167	PAR-CLIP	20371350
MIRT574494	hsa-miR-876-5p	PAR-CLIP	20371350
MIRT574493	hsa-miR-3159	PAR-CLIP	20371350
MIRT574492	hsa-miR-4490	PAR-CLIP	20371350
MIRT574491	hsa-miR-4774-5p	PAR-CLIP	20371350
MIRT574490	hsa-miR-27a-5p	PAR-CLIP	20371350
MIRT574489	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT574488	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT574487	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT574486	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT574485	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT574484	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT574483	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT574482	hsa-miR-548a-3p	PAR-CLIP	20371350
MIRT574481	hsa-miR-548ar-3p	PAR-CLIP	20371350
MIRT574480	hsa-miR-548az-3p	PAR-CLIP	20371350
MIRT574479	hsa-miR-548e-3p	PAR-CLIP	20371350
MIRT574478	hsa-miR-548f-3p	PAR-CLIP	20371350
MIRT574477	hsa-miR-548g-3p	PAR-CLIP	20371350
MIRT574475	hsa-miR-6882-5p	PAR-CLIP	20371350
MIRT574476	hsa-miR-452-5p	PAR-CLIP	20371350
MIRT574474	hsa-miR-4676-3p	PAR-CLIP	20371350
MIRT574473	hsa-miR-892c-3p	PAR-CLIP	20371350
MIRT574472	hsa-miR-3174	PAR-CLIP	20371350
MIRT574471	hsa-miR-300	PAR-CLIP	20371350
MIRT574470	hsa-miR-381-3p	PAR-CLIP	20371350
MIRT574468	hsa-miR-4666a-3p	PAR-CLIP	20371350
MIRT574469	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT082273	hsa-miR-371b-5p	PAR-CLIP	20371350
MIRT082260	hsa-miR-373-5p	PAR-CLIP	20371350
MIRT082263	hsa-miR-616-5p	PAR-CLIP	20371350
MIRT574467	hsa-miR-5702	PAR-CLIP	20371350
MIRT574466	hsa-miR-2052	PAR-CLIP	20371350
MIRT574465	hsa-let-7a-3p	PAR-CLIP	20371350
MIRT574464	hsa-let-7b-3p	PAR-CLIP	20371350
MIRT574463	hsa-let-7f-1-3p	PAR-CLIP	20371350
MIRT574462	hsa-miR-98-3p	PAR-CLIP	20371350
MIRT574461	hsa-miR-4789-5p	PAR-CLIP	20371350
MIRT574460	hsa-let-7f-2-3p	PAR-CLIP	20371350
MIRT574459	hsa-miR-1185-1-3p	PAR-CLIP	20371350
MIRT574458	hsa-miR-1185-2-3p	PAR-CLIP	20371350
MIRT574457	hsa-miR-4795-3p	PAR-CLIP	20371350
MIRT574456	hsa-miR-937-5p	PAR-CLIP	20371350
MIRT574455	hsa-miR-627-5p	PAR-CLIP	20371350
MIRT574454	hsa-miR-8081	PAR-CLIP	20371350
MIRT574453	hsa-miR-8055	PAR-CLIP	20371350
MIRT1317719	hsa-miR-381	CLIP-seq
MIRT1317720	hsa-miR-452	CLIP-seq
MIRT1317721	hsa-miR-4666-3p	CLIP-seq
MIRT1317722	hsa-miR-4668-3p	CLIP-seq
MIRT1317723	hsa-miR-548ae	CLIP-seq
MIRT1317724	hsa-miR-548aj	CLIP-seq
MIRT1317725	hsa-miR-548am	CLIP-seq
MIRT1317726	hsa-miR-548e	CLIP-seq
MIRT1317727	hsa-miR-548f	CLIP-seq
MIRT1317728	hsa-miR-548g	CLIP-seq
MIRT1317729	hsa-miR-548x	CLIP-seq
MIRT1317730	hsa-miR-605	CLIP-seq
MIRT1317731	hsa-miR-627	CLIP-seq
MIRT1317719	hsa-miR-381	CLIP-seq
MIRT1317721	hsa-miR-4666-3p	CLIP-seq
MIRT1317731	hsa-miR-627	CLIP-seq
MIRT1317719	hsa-miR-381	CLIP-seq
MIRT1317721	hsa-miR-4666-3p	CLIP-seq
MIRT1317731	hsa-miR-627	CLIP-seq

40 Show/Hide all (40)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000462	Process	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA
GO:0002181	Process	Cytoplasmic translation	IC	23636399
GO:0002181	Process	Cytoplasmic translation	NAS	25901680
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IDA	17881366
GO:0003735	Function	Structural constituent of ribosome	HDA	15883184
GO:0003735	Function	Structural constituent of ribosome	IBA
GO:0003735	Function	Structural constituent of ribosome	IDA	23636399
GO:0003735	Function	Structural constituent of ribosome	IEA
GO:0003735	Function	Structural constituent of ribosome	IMP	18697920
GO:0005515	Function	Protein binding	IPI	24725412, 30021884, 31046837, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	NAS	25901680
GO:0005829	Component	Cytosol	TAS
GO:0005840	Component	Ribosome	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0006364	Process	RRNA processing	IMP	18697920
GO:0006412	Process	Translation	IC	8706699, 15883184
GO:0006412	Process	Translation	IEA
GO:0006412	Process	Translation	NAS	12082018
GO:0015935	Component	Small ribosomal subunit	HDA	15883184
GO:0016020	Component	Membrane	HDA	19946888
GO:0022626	Component	Cytosolic ribosome	IDA	23636399
GO:0022626	Component	Cytosolic ribosome	IEA
GO:0022627	Component	Cytosolic small ribosomal subunit	HDA	15883184
GO:0022627	Component	Cytosolic small ribosomal subunit	IBA
GO:0022627	Component	Cytosolic small ribosomal subunit	IDA	8706699
GO:0022627	Component	Cytosolic small ribosomal subunit	IEA
GO:0022627	Component	Cytosolic small ribosomal subunit	NAS	2016298, 25901680
GO:0032040	Component	Small-subunit processome	IDA	34516797
GO:0042274	Process	Ribosomal small subunit biogenesis	IDA	34516797
GO:0042274	Process	Ribosomal small subunit biogenesis	IMP	18697920
GO:0045202	Component	Synapse	IEA
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:1990830	Process	Cellular response to leukemia inhibitory factor	IEA
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
603675	10396	ENSG00000105193

P62249

Protein name

Small ribosomal subunit protein uS9 (40S ribosomal protein S16)

Protein function

Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of

PDB

4UG0 , 4V6X , 5A2Q , 5AJ0 , 5FLX , 5LKS , 5OA3 , 5T2C , 5VYC , 6FEC , 6G18 , 6G4S , 6G4W , 6G51 , 6G53 , 6G5H , 6G5I , 6IP5 , 6IP6 , 6IP8 , 6OLE , 6OLF , 6OLG , 6OLI , 6OLZ , 6OM0 , 6OM7 , 6QZP , 6XA1 , 6Y0G , 6Y2L , 6Y57 , 6YBS , 6Z6L , 6Z6M , 6Z6N , 6ZLW , 6ZM7 , 6ZME , 6ZMI , 6ZMO , 6ZMT , 6ZMW , 6ZN5 , 6ZOJ , 6ZOL , 6ZON , 6ZP4 , 6ZUO , 6ZV6 , 6ZVH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00380	Ribosomal_S9	14 → 146	Ribosomal protein S9/S16	Family

Sequence

MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGK
ERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLL
VADPRRCESKKFGGPGARARYQKSYR

Sequence length

146

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Ribosome	L13a-mediated translational silencing of Ceruloplasmin expression
Coronavirus disease - COVID-19	SRP-dependent cotranslational protein targeting to membrane
	Viral mRNA Translation
	Major pathway of rRNA processing in the nucleolus and cytosol
	Translation initiation complex formation
	Formation of a pool of free 40S subunits
	Formation of the ternary complex, and subsequently, the 43S complex
	Ribosomal scanning and start codon recognition
	GTP hydrolysis and joining of the 60S ribosomal subunit
	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Related Gene	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Names
RPS4Y2	[]	13	["Ribosome","Coronavirus disease - COVID-19","Major pathway of rRNA processing in the nucleolus and cytosol","L13a-mediated translational silencing of Ceruloplasmin expression","Translation initiation complex formation","Formation of a pool of free 40S subunits","Formation of the ternary complex, and subsequently, the 43S complex","Ribosomal scanning and start codon recognition","GTP hydrolysis and joining of the 60S ribosomal subunit","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)","SRP-dependent cotranslational protein targeting to membrane","Viral mRNA Translation"]	[]
RPSA	[]	13	["Ribosome","Coronavirus disease - COVID-19","Major pathway of rRNA processing in the nucleolus and cytosol","L13a-mediated translational silencing of Ceruloplasmin expression","Translation initiation complex formation","Formation of a pool of free 40S subunits","Formation of the ternary complex, and subsequently, the 43S complex","Ribosomal scanning and start codon recognition","GTP hydrolysis and joining of the 60S ribosomal subunit","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)","SRP-dependent cotranslational protein targeting to membrane","Viral mRNA Translation"]	[]
RPS27L	[]	13	["Ribosome","Coronavirus disease - COVID-19","Major pathway of rRNA processing in the nucleolus and cytosol","L13a-mediated translational silencing of Ceruloplasmin expression","Translation initiation complex formation","Formation of a pool of free 40S subunits","Formation of the ternary complex, and subsequently, the 43S complex","Ribosomal scanning and start codon recognition","GTP hydrolysis and joining of the 60S ribosomal subunit","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)","SRP-dependent cotranslational protein targeting to membrane","Viral mRNA Translation"]	[]
RPS3A	[]	13	["Ribosome","Coronavirus disease - COVID-19","Major pathway of rRNA processing in the nucleolus and cytosol","L13a-mediated translational silencing of Ceruloplasmin expression","Translation initiation complex formation","Formation of a pool of free 40S subunits","Formation of the ternary complex, and subsequently, the 43S complex","Ribosomal scanning and start codon recognition","GTP hydrolysis and joining of the 60S ribosomal subunit","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)","SRP-dependent cotranslational protein targeting to membrane","Viral mRNA Translation"]	[]
RPS4X	[]	13	["Ribosome","Coronavirus disease - COVID-19","Major pathway of rRNA processing in the nucleolus and cytosol","L13a-mediated translational silencing of Ceruloplasmin expression","Translation initiation complex formation","Formation of a pool of free 40S subunits","Formation of the ternary complex, and subsequently, the 43S complex","Ribosomal scanning and start codon recognition","GTP hydrolysis and joining of the 60S ribosomal subunit","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)","SRP-dependent cotranslational protein targeting to membrane","Viral mRNA Translation"]	[]

RPS16 (ribosomal protein S16)

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