Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	6118
Gene name	Replication protein A2
Gene symbol	RPA2
Synonyms (NCBI Gene)	REPA2RP-A p32RP-A p34RPA32
Chromosome	1
Chromosome location	1p35.3
Summary	This gene encodes a subunit of the heterotrimeric Replication Protein A (RPA) complex, which binds to single-stranded DNA (ssDNA), forming a nucleoprotein complex that plays an important role in DNA metabolism, being involved in DNA replication, repair, r

275 Show/Hide all (275)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020141	hsa-miR-130b-3p	Sequencing	20371350
MIRT027975	hsa-miR-93-5p	Sequencing	20371350
MIRT031089	hsa-miR-19b-3p	Sequencing	20371350
MIRT050504	hsa-miR-20a-5p	CLASH	23622248
MIRT049074	hsa-miR-92a-3p	CLASH	23622248
MIRT036453	hsa-miR-1226-3p	CLASH	23622248
MIRT439745	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT050504	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT439745	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT726697	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT726696	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT027975	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT726695	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT050504	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT726694	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT726693	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT726692	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT726690	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT726691	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT1315424	hsa-miR-1913	CLIP-seq
MIRT1315425	hsa-miR-27a	CLIP-seq
MIRT1315426	hsa-miR-27b	CLIP-seq
MIRT1315427	hsa-miR-3064-3p	CLIP-seq
MIRT1315428	hsa-miR-3150b-3p	CLIP-seq
MIRT1315429	hsa-miR-324-3p	CLIP-seq
MIRT1315430	hsa-miR-331-3p	CLIP-seq
MIRT1315431	hsa-miR-3612	CLIP-seq
MIRT1315432	hsa-miR-365	CLIP-seq
MIRT1315433	hsa-miR-4254	CLIP-seq
MIRT1315434	hsa-miR-4257	CLIP-seq
MIRT1315435	hsa-miR-4308	CLIP-seq
MIRT1315436	hsa-miR-4443	CLIP-seq
MIRT1315437	hsa-miR-4742-3p	CLIP-seq
MIRT1315438	hsa-miR-4749-3p	CLIP-seq
MIRT1315439	hsa-miR-4766-5p	CLIP-seq
MIRT1315440	hsa-miR-4784	CLIP-seq
MIRT1315441	hsa-miR-513a-5p	CLIP-seq
MIRT1315442	hsa-miR-520g	CLIP-seq
MIRT1315443	hsa-miR-520h	CLIP-seq
MIRT1315444	hsa-miR-548a-5p	CLIP-seq
MIRT1315445	hsa-miR-548ab	CLIP-seq
MIRT1315446	hsa-miR-548ak	CLIP-seq
MIRT1315447	hsa-miR-548b-5p	CLIP-seq
MIRT1315448	hsa-miR-548c-5p	CLIP-seq
MIRT1315449	hsa-miR-548d-5p	CLIP-seq
MIRT1315450	hsa-miR-548h	CLIP-seq
MIRT1315451	hsa-miR-548i	CLIP-seq
MIRT1315452	hsa-miR-548j	CLIP-seq
MIRT1315453	hsa-miR-548w	CLIP-seq
MIRT1315454	hsa-miR-548y	CLIP-seq
MIRT1315455	hsa-miR-559	CLIP-seq
MIRT1315456	hsa-miR-607	CLIP-seq
MIRT1315457	hsa-miR-650	CLIP-seq
MIRT1315458	hsa-miR-943	CLIP-seq
MIRT1315425	hsa-miR-27a	CLIP-seq
MIRT1315426	hsa-miR-27b	CLIP-seq
MIRT1315427	hsa-miR-3064-3p	CLIP-seq
MIRT1315430	hsa-miR-331-3p	CLIP-seq
MIRT1315431	hsa-miR-3612	CLIP-seq
MIRT1315433	hsa-miR-4254	CLIP-seq
MIRT1315435	hsa-miR-4308	CLIP-seq
MIRT1315436	hsa-miR-4443	CLIP-seq
MIRT1315441	hsa-miR-513a-5p	CLIP-seq
MIRT1315442	hsa-miR-520g	CLIP-seq
MIRT1315443	hsa-miR-520h	CLIP-seq
MIRT1315457	hsa-miR-650	CLIP-seq
MIRT2318302	hsa-miR-106a	CLIP-seq
MIRT2318303	hsa-miR-106b	CLIP-seq
MIRT2318304	hsa-miR-1200	CLIP-seq
MIRT2318305	hsa-miR-1238	CLIP-seq
MIRT2318306	hsa-miR-130a	CLIP-seq
MIRT2318307	hsa-miR-130b	CLIP-seq
MIRT2318308	hsa-miR-141	CLIP-seq
MIRT2318309	hsa-miR-17	CLIP-seq
MIRT1315424	hsa-miR-1913	CLIP-seq
MIRT2318310	hsa-miR-200a	CLIP-seq
MIRT2318311	hsa-miR-20a	CLIP-seq
MIRT2318312	hsa-miR-20b	CLIP-seq
MIRT2318313	hsa-miR-214	CLIP-seq
MIRT2318314	hsa-miR-2467-3p	CLIP-seq
MIRT1315425	hsa-miR-27a	CLIP-seq
MIRT1315426	hsa-miR-27b	CLIP-seq
MIRT2318315	hsa-miR-301a	CLIP-seq
MIRT2318316	hsa-miR-301b	CLIP-seq
MIRT1315427	hsa-miR-3064-3p	CLIP-seq
MIRT2318317	hsa-miR-30a	CLIP-seq
MIRT2318318	hsa-miR-30b	CLIP-seq
MIRT2318319	hsa-miR-30c	CLIP-seq
MIRT2318320	hsa-miR-30d	CLIP-seq
MIRT2318321	hsa-miR-30e	CLIP-seq
MIRT2318322	hsa-miR-3135b	CLIP-seq
MIRT1315428	hsa-miR-3150b-3p	CLIP-seq
MIRT2318323	hsa-miR-3153	CLIP-seq
MIRT1315429	hsa-miR-324-3p	CLIP-seq
MIRT2318324	hsa-miR-324-5p	CLIP-seq
MIRT1315430	hsa-miR-331-3p	CLIP-seq
MIRT2318325	hsa-miR-339-5p	CLIP-seq
MIRT2318326	hsa-miR-3611	CLIP-seq
MIRT1315431	hsa-miR-3612	CLIP-seq
MIRT2318327	hsa-miR-3619-5p	CLIP-seq
MIRT2318328	hsa-miR-3646	CLIP-seq
MIRT2318329	hsa-miR-3653	CLIP-seq
MIRT2318330	hsa-miR-3658	CLIP-seq
MIRT2318331	hsa-miR-3663-3p	CLIP-seq
MIRT2318332	hsa-miR-3666	CLIP-seq
MIRT2318333	hsa-miR-3678-3p	CLIP-seq
MIRT2318334	hsa-miR-380	CLIP-seq
MIRT2318335	hsa-miR-3943	CLIP-seq
MIRT1315433	hsa-miR-4254	CLIP-seq
MIRT1315434	hsa-miR-4257	CLIP-seq
MIRT2318336	hsa-miR-4291	CLIP-seq
MIRT2318337	hsa-miR-4295	CLIP-seq
MIRT1315435	hsa-miR-4308	CLIP-seq
MIRT2318338	hsa-miR-4313	CLIP-seq
MIRT2318339	hsa-miR-4324	CLIP-seq
MIRT2318340	hsa-miR-4435	CLIP-seq
MIRT1315436	hsa-miR-4443	CLIP-seq
MIRT2318341	hsa-miR-4487	CLIP-seq
MIRT2318342	hsa-miR-4495	CLIP-seq
MIRT2318343	hsa-miR-454	CLIP-seq
MIRT2318344	hsa-miR-4659a-3p	CLIP-seq
MIRT2318345	hsa-miR-4659b-3p	CLIP-seq
MIRT2318346	hsa-miR-4668-5p	CLIP-seq
MIRT1315438	hsa-miR-4749-3p	CLIP-seq
MIRT1315439	hsa-miR-4766-5p	CLIP-seq
MIRT2318347	hsa-miR-4778-3p	CLIP-seq
MIRT1315440	hsa-miR-4784	CLIP-seq
MIRT2318348	hsa-miR-4796-3p	CLIP-seq
MIRT1315441	hsa-miR-513a-5p	CLIP-seq
MIRT2318349	hsa-miR-519a	CLIP-seq
MIRT2318350	hsa-miR-519b-3p	CLIP-seq
MIRT2318351	hsa-miR-519c-3p	CLIP-seq
MIRT2318352	hsa-miR-519d	CLIP-seq
MIRT1315442	hsa-miR-520g	CLIP-seq
MIRT1315443	hsa-miR-520h	CLIP-seq
MIRT2318353	hsa-miR-544b	CLIP-seq
MIRT1315444	hsa-miR-548a-5p	CLIP-seq
MIRT1315445	hsa-miR-548ab	CLIP-seq
MIRT1315446	hsa-miR-548ak	CLIP-seq
MIRT1315447	hsa-miR-548b-5p	CLIP-seq
MIRT1315448	hsa-miR-548c-5p	CLIP-seq
MIRT1315449	hsa-miR-548d-5p	CLIP-seq
MIRT1315450	hsa-miR-548h	CLIP-seq
MIRT1315451	hsa-miR-548i	CLIP-seq
MIRT1315452	hsa-miR-548j	CLIP-seq
MIRT1315453	hsa-miR-548w	CLIP-seq
MIRT1315454	hsa-miR-548y	CLIP-seq
MIRT1315455	hsa-miR-559	CLIP-seq
MIRT2318354	hsa-miR-570	CLIP-seq
MIRT1315456	hsa-miR-607	CLIP-seq
MIRT1315457	hsa-miR-650	CLIP-seq
MIRT2318355	hsa-miR-761	CLIP-seq
MIRT2318356	hsa-miR-802	CLIP-seq
MIRT2318357	hsa-miR-922	CLIP-seq
MIRT2318358	hsa-miR-93	CLIP-seq
MIRT1315430	hsa-miR-331-3p	CLIP-seq
MIRT2318304	hsa-miR-1200	CLIP-seq
MIRT2614109	hsa-miR-1266	CLIP-seq
MIRT2614110	hsa-miR-1307	CLIP-seq
MIRT2614111	hsa-miR-1912	CLIP-seq
MIRT2318313	hsa-miR-214	CLIP-seq
MIRT2318314	hsa-miR-2467-3p	CLIP-seq
MIRT1315427	hsa-miR-3064-3p	CLIP-seq
MIRT2318317	hsa-miR-30a	CLIP-seq
MIRT2318318	hsa-miR-30b	CLIP-seq
MIRT2318319	hsa-miR-30c	CLIP-seq
MIRT2318320	hsa-miR-30d	CLIP-seq
MIRT2318321	hsa-miR-30e	CLIP-seq
MIRT2614112	hsa-miR-3130-5p	CLIP-seq
MIRT2318322	hsa-miR-3135b	CLIP-seq
MIRT2318323	hsa-miR-3153	CLIP-seq
MIRT2614113	hsa-miR-3158-3p	CLIP-seq
MIRT2614114	hsa-miR-3194-3p	CLIP-seq
MIRT1315430	hsa-miR-331-3p	CLIP-seq
MIRT2614115	hsa-miR-3607-3p	CLIP-seq
MIRT2318326	hsa-miR-3611	CLIP-seq
MIRT2318327	hsa-miR-3619-5p	CLIP-seq
MIRT2318328	hsa-miR-3646	CLIP-seq
MIRT2318329	hsa-miR-3653	CLIP-seq
MIRT2318330	hsa-miR-3658	CLIP-seq
MIRT2318331	hsa-miR-3663-3p	CLIP-seq
MIRT2614116	hsa-miR-3664-3p	CLIP-seq
MIRT2318333	hsa-miR-3678-3p	CLIP-seq
MIRT2614117	hsa-miR-370	CLIP-seq
MIRT2318334	hsa-miR-380	CLIP-seq
MIRT2614118	hsa-miR-384	CLIP-seq
MIRT2318335	hsa-miR-3943	CLIP-seq
MIRT2614119	hsa-miR-4267	CLIP-seq
MIRT2318336	hsa-miR-4291	CLIP-seq
MIRT2318338	hsa-miR-4313	CLIP-seq
MIRT2318339	hsa-miR-4324	CLIP-seq
MIRT2318340	hsa-miR-4435	CLIP-seq
MIRT2614120	hsa-miR-4446-3p	CLIP-seq
MIRT2614121	hsa-miR-4477a	CLIP-seq
MIRT2614122	hsa-miR-4482	CLIP-seq
MIRT2318341	hsa-miR-4487	CLIP-seq
MIRT2318342	hsa-miR-4495	CLIP-seq
MIRT2614123	hsa-miR-4514	CLIP-seq
MIRT2614124	hsa-miR-4518	CLIP-seq
MIRT2614125	hsa-miR-452	CLIP-seq
MIRT2614126	hsa-miR-4530	CLIP-seq
MIRT2614127	hsa-miR-4638-5p	CLIP-seq
MIRT2318346	hsa-miR-4668-5p	CLIP-seq
MIRT2614128	hsa-miR-4676-3p	CLIP-seq
MIRT2614129	hsa-miR-4692	CLIP-seq
MIRT2614130	hsa-miR-4738-3p	CLIP-seq
MIRT2318348	hsa-miR-4796-3p	CLIP-seq
MIRT1315442	hsa-miR-520g	CLIP-seq
MIRT1315443	hsa-miR-520h	CLIP-seq
MIRT2318353	hsa-miR-544b	CLIP-seq
MIRT2318354	hsa-miR-570	CLIP-seq
MIRT2614131	hsa-miR-614	CLIP-seq
MIRT2614132	hsa-miR-657	CLIP-seq
MIRT2614133	hsa-miR-760	CLIP-seq
MIRT2318355	hsa-miR-761	CLIP-seq
MIRT2614134	hsa-miR-767-3p	CLIP-seq
MIRT2318357	hsa-miR-922	CLIP-seq
MIRT2614109	hsa-miR-1266	CLIP-seq
MIRT2614110	hsa-miR-1307	CLIP-seq
MIRT2614111	hsa-miR-1912	CLIP-seq
MIRT2689910	hsa-miR-194	CLIP-seq
MIRT2689911	hsa-miR-21	CLIP-seq
MIRT2318313	hsa-miR-214	CLIP-seq
MIRT2318314	hsa-miR-2467-3p	CLIP-seq
MIRT1315427	hsa-miR-3064-3p	CLIP-seq
MIRT2318317	hsa-miR-30a	CLIP-seq
MIRT2318318	hsa-miR-30b	CLIP-seq
MIRT2318319	hsa-miR-30c	CLIP-seq
MIRT2318320	hsa-miR-30d	CLIP-seq
MIRT2318321	hsa-miR-30e	CLIP-seq
MIRT2614112	hsa-miR-3130-5p	CLIP-seq
MIRT2318322	hsa-miR-3135b	CLIP-seq
MIRT2318323	hsa-miR-3153	CLIP-seq
MIRT2614113	hsa-miR-3158-3p	CLIP-seq
MIRT2614114	hsa-miR-3194-3p	CLIP-seq
MIRT1315430	hsa-miR-331-3p	CLIP-seq
MIRT2614115	hsa-miR-3607-3p	CLIP-seq
MIRT2689912	hsa-miR-3613-5p	CLIP-seq
MIRT2318327	hsa-miR-3619-5p	CLIP-seq
MIRT2318328	hsa-miR-3646	CLIP-seq
MIRT2318329	hsa-miR-3653	CLIP-seq
MIRT2318330	hsa-miR-3658	CLIP-seq
MIRT2614116	hsa-miR-3664-3p	CLIP-seq
MIRT2318333	hsa-miR-3678-3p	CLIP-seq
MIRT2614117	hsa-miR-370	CLIP-seq
MIRT2614118	hsa-miR-384	CLIP-seq
MIRT2318335	hsa-miR-3943	CLIP-seq
MIRT2614119	hsa-miR-4267	CLIP-seq
MIRT2318336	hsa-miR-4291	CLIP-seq
MIRT2318338	hsa-miR-4313	CLIP-seq
MIRT2318340	hsa-miR-4435	CLIP-seq
MIRT2614120	hsa-miR-4446-3p	CLIP-seq
MIRT2614121	hsa-miR-4477a	CLIP-seq
MIRT2614122	hsa-miR-4482	CLIP-seq
MIRT2318341	hsa-miR-4487	CLIP-seq
MIRT2614123	hsa-miR-4514	CLIP-seq
MIRT2614124	hsa-miR-4518	CLIP-seq
MIRT2614125	hsa-miR-452	CLIP-seq
MIRT2614126	hsa-miR-4530	CLIP-seq
MIRT2614127	hsa-miR-4638-5p	CLIP-seq
MIRT2318346	hsa-miR-4668-5p	CLIP-seq
MIRT2614128	hsa-miR-4676-3p	CLIP-seq
MIRT2614129	hsa-miR-4692	CLIP-seq
MIRT2614130	hsa-miR-4738-3p	CLIP-seq
MIRT2318348	hsa-miR-4796-3p	CLIP-seq
MIRT1315442	hsa-miR-520g	CLIP-seq
MIRT1315443	hsa-miR-520h	CLIP-seq
MIRT2318354	hsa-miR-570	CLIP-seq
MIRT2689913	hsa-miR-590-5p	CLIP-seq
MIRT2614131	hsa-miR-614	CLIP-seq
MIRT2614132	hsa-miR-657	CLIP-seq
MIRT2614133	hsa-miR-760	CLIP-seq
MIRT2318355	hsa-miR-761	CLIP-seq
MIRT2614134	hsa-miR-767-3p	CLIP-seq
MIRT2318357	hsa-miR-922	CLIP-seq

Transcription factor	Regulation	Reference
E2F1	Unknown	11313881

53 Show/Hide all (53)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000077	Process	DNA damage checkpoint signaling	IEA
GO:0000723	Process	Telomere maintenance	IC	24747047
GO:0000723	Process	Telomere maintenance	IMP	17959650
GO:0000723	Process	Telomere maintenance	NAS	17959650
GO:0000724	Process	Double-strand break repair via homologous recombination	IBA
GO:0000724	Process	Double-strand break repair via homologous recombination	IMP	17765923
GO:0000724	Process	Double-strand break repair via homologous recombination	NAS	17765923
GO:0000781	Component	Chromosome, telomeric region	HDA	19135898
GO:0000781	Component	Chromosome, telomeric region	IDA	17959650
GO:0000785	Component	Chromatin	IDA	10336450
GO:0003677	Function	DNA binding	IEA
GO:0003684	Function	Damaged DNA binding	IDA	7700386, 27723717, 27723720
GO:0003697	Function	Single-stranded DNA binding	IBA
GO:0003697	Function	Single-stranded DNA binding	IC	2406247
GO:0003697	Function	Single-stranded DNA binding	IDA	19010961
GO:0003697	Function	Single-stranded DNA binding	ISS
GO:0005515	Function	Protein binding	IPI	2159011, 7700386, 7760808, 8702565, 10449415, 10982866, 11927569, 12509449, 12527904, 15897895, 15965237, 16169070, 17765923, 19338310, 20154705, 20304803, 20643958, 20670893, 20811460, 22684010, 23910567, 24126761, 24910198, 24981860, 26496610, 27723717, 27723720, 28575657, 2857565
GO:0005634	Component	Nucleus	IDA	10982866
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005662	Component	DNA replication factor A complex	IBA
GO:0005662	Component	DNA replication factor A complex	IDA	2406247, 11927569, 27723717, 27723720
GO:0005662	Component	DNA replication factor A complex	IEA
GO:0005662	Component	DNA replication factor A complex	IPI	11927569
GO:0006260	Process	DNA replication	IBA
GO:0006260	Process	DNA replication	IDA	2406247
GO:0006260	Process	DNA replication	IEA
GO:0006260	Process	DNA replication	IMP	9430682
GO:0006260	Process	DNA replication	NAS	9430682
GO:0006281	Process	DNA repair	IEA
GO:0006284	Process	Base-excision repair	IDA	9765279
GO:0006289	Process	Nucleotide-excision repair	IBA
GO:0006289	Process	Nucleotide-excision repair	IEA
GO:0006289	Process	Nucleotide-excision repair	IMP	9430682
GO:0006289	Process	Nucleotide-excision repair	NAS	9430682
GO:0006298	Process	Mismatch repair	IMP	9430682
GO:0006310	Process	DNA recombination	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0010569	Process	Regulation of double-strand break repair via homologous recombination	IMP	20154705
GO:0016604	Component	Nuclear body	IDA
GO:0016605	Component	PML body	IDA	17959650
GO:0016605	Component	PML body	IDA	12814551
GO:0016605	Component	PML body	IEA
GO:0019899	Function	Enzyme binding	IPI	19793862, 19793863
GO:0019903	Function	Protein phosphatase binding	IPI	20154705
GO:0031571	Process	Mitotic G1 DNA damage checkpoint signaling	IMP	21731742
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	21504906
GO:0034502	Process	Protein localization to chromosome	IDA	27723717, 27723720
GO:0035861	Component	Site of double-strand break	IDA	21504906
GO:0042162	Function	Telomeric DNA binding	IBA
GO:0098505	Function	G-rich strand telomeric DNA binding	IDA	24747047
GO:2000001	Process	Regulation of DNA damage checkpoint	IMP	21504906

MIM	HGNC	e!Ensembl
179836	10290	ENSG00000117748

P15927

Protein name

Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)

Protein function

As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activ

PDB

1DPU , 1L1O , 1QUQ , 1Z1D , 2PI2 , 2PQA , 2Z6K , 3KDF , 4MQV , 4OU0 , 8RK2 , 9MJ5

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08784	RPA_C	166 → 262	Replication protein A C terminal	Domain

Sequence

MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLV
DEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVV
PPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGR
APISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVS
SIKQAVDFLSNEGHIYSTVDDDHFKSTDAE

Sequence length

270

Interactions

View interactions

KEGG Pathway	Reactome Pathway
DNA replication	Translesion synthesis by REV1
Nucleotide excision repair	Recognition of DNA damage by PCNA-containing replication complex
Mismatch repair	Translesion Synthesis by POLH
Homologous recombination	Removal of the Flap Intermediate from the C-strand
Fanconi anemia pathway	Activation of ATR in response to replication stress
	Regulation of HSF1-mediated heat shock response
	HSF1 activation
	Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
	Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
	PCNA-Dependent Long Patch Base Excision Repair
	Translesion synthesis by POLK
	Translesion synthesis by POLI
	Termination of translesion DNA synthesis
	HDR through Single Strand Annealing (SSA)
	HDR through Homologous Recombination (HRR)
	Processing of DNA double-strand break ends
	Presynaptic phase of homologous DNA pairing and strand exchange
	Formation of Incision Complex in GG-NER
	Gap-filling DNA repair synthesis and ligation in GG-NER
	Dual Incision in GG-NER
	Dual incision in TC-NER
	Gap-filling DNA repair synthesis and ligation in TC-NER
	Fanconi Anemia Pathway
	Regulation of TP53 Activity through Phosphorylation
	Activation of the pre-replicative complex
	Removal of the Flap Intermediate
	G2/M DNA damage checkpoint

Related Gene	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Names
RPA3	[]	31	["DNA replication","Nucleotide excision repair","Mismatch repair","Homologous recombination","Fanconi anemia pathway","HSF1 activation","Formation of Incision Complex in GG-NER","Dual Incision in GG-NER","Regulation of HSF1-mediated heat shock response","Dual incision in TC-NER","Gap-filling DNA repair synthesis and ligation in TC-NER","HDR through Single Strand Annealing (SSA)"]	[]
RPA1	[]	31	["DNA replication","Nucleotide excision repair","Mismatch repair","Homologous recombination","Fanconi anemia pathway","HSF1 activation","Formation of Incision Complex in GG-NER","Dual Incision in GG-NER","Regulation of HSF1-mediated heat shock response","Dual incision in TC-NER","Gap-filling DNA repair synthesis and ligation in TC-NER","HDR through Single Strand Annealing (SSA)"]	[]
RFC2	[]	21	["DNA replication","Nucleotide excision repair","Mismatch repair","Dual Incision in GG-NER","Dual incision in TC-NER","Gap-filling DNA repair synthesis and ligation in TC-NER","HDR through Single Strand Annealing (SSA)","HDR through Homologous Recombination (HRR)","Processing of DNA double-strand break ends","Presynaptic phase of homologous DNA pairing and strand exchange","Regulation of TP53 Activity through Phosphorylation","G2\/M DNA damage checkpoint"]	[]
RFC3	[]	21	["DNA replication","Nucleotide excision repair","Mismatch repair","Dual Incision in GG-NER","Dual incision in TC-NER","Gap-filling DNA repair synthesis and ligation in TC-NER","HDR through Single Strand Annealing (SSA)","HDR through Homologous Recombination (HRR)","Processing of DNA double-strand break ends","Presynaptic phase of homologous DNA pairing and strand exchange","Regulation of TP53 Activity through Phosphorylation","G2\/M DNA damage checkpoint"]	[]
RFC4	[]	21	["DNA replication","Nucleotide excision repair","Mismatch repair","Dual Incision in GG-NER","Dual incision in TC-NER","Gap-filling DNA repair synthesis and ligation in TC-NER","HDR through Single Strand Annealing (SSA)","HDR through Homologous Recombination (HRR)","Processing of DNA double-strand break ends","Presynaptic phase of homologous DNA pairing and strand exchange","Regulation of TP53 Activity through Phosphorylation","G2\/M DNA damage checkpoint"]	[]

RPA2 (replication protein A2)

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