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Gene Gene information from NCBI Gene database.
Entrez ID 9727
Gene name RAB11 family interacting protein 3
Gene symbol RAB11FIP3
Synonyms (NCBI Gene)
CART1FIP3FIP3-Rab11Rab11-FIP3
Chromosome 16
Chromosome location 16p13.3
Summary Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al.,
miRNA miRNA information provided by mirtarbase database.
182 Show/Hide all (182)
miRTarBase ID miRNA Experiments Reference
MIRT042127 hsa-miR-484 CLASH 23622248
MIRT552070 hsa-miR-5011-5p HITS-CLIP 21572407
MIRT552069 hsa-miR-205-3p HITS-CLIP 21572407
MIRT552068 hsa-miR-3607-5p HITS-CLIP 21572407
MIRT552067 hsa-miR-190a-3p HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
82 Show/Hide all (82)
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IDA 25673879
GO:0000139 Component Golgi membrane IEA
GO:0000281 Process Mitotic cytokinesis IC 18511905
GO:0005509 Function Calcium ion binding IEA
GO:0005515 Function Protein binding IPI 12470645, 16148947, 17007872, 17030804, 18511905, 24876499, 25673879, 26258637
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608738 17224 ENSG00000090565
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75154
Protein name Rab11 family-interacting protein 3 (FIP3) (FIP3-Rab11) (Rab11-FIP3) (Arfophilin-1) (EF hands-containing Rab-interacting protein) (Eferin) (MU-MB-17.148)
Protein function Downstream effector molecule for Rab11 GTPase which is involved in endocytic trafficking, cytokinesis and intracellular ciliogenesis by participating in membrane delivery (PubMed:15601896, PubMed:16148947, PubMed:17394487, PubMed:17628206, PubMe
PDB 2D7C , 2HV8 , 4D0M , 4UJ3 , 4UJ4
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09457 RBD-FIP 716 → 756 FIP domain Motif
Sequence
MASAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAP
GAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPELD
PLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGS
PPQPSDLSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYGAEQVK
DLTKYLDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTY
EANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEE
PDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLT
PSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDT
AATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIE
IENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRM
GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE
SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDEL
MEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK
Sequence length 756
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Endocytosis VxPx cargo-targeting to cilium