POLDIP3 (DNA polymerase delta interacting protein 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 84271 |
| Gene name | DNA polymerase delta interacting protein 3 |
| Gene symbol | POLDIP3 |
| Synonyms (NCBI Gene) |
PDIP3PDIP46SKAR
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| Chromosome | 22 |
| Chromosome location | 22q13.2 |
| Summary | This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by Re |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9BY77 | ||||||||||
| Protein name | Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR) | ||||||||||
| Protein function | Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI |
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| Sequence length | 421 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with POLDIP3 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to POLDIP3 (see Related Genes above), that are NOT already directly curated for POLDIP3 itself -- a lead worth checking, not a confirmed association.
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