NBR1 (NBR1 autophagy cargo receptor)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 4077
• Gene name: NBR1 autophagy cargo receptor
• Gene symbol: NBR1
• Synonyms (NCBI Gene): 1A1-3B, IAI3B, M17S2, MIG19
• Chromosome: 17
• Chromosome location: 17q21.31
• Summary: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a spe

miRNA Show/Hide all (373)

miRTarBase ID	miRNA	Experiments	Reference
MIRT050957	hsa-miR-17-5p	CLASH	23622248
MIRT049785	hsa-miR-92a-3p	CLASH	23622248
MIRT040928	hsa-miR-18a-3p	CLASH	23622248
MIRT039971	hsa-miR-615-3p	CLASH	23622248
MIRT1175529	hsa-miR-15a	CLIP-seq
MIRT1175530	hsa-miR-15b	CLIP-seq
MIRT1175531	hsa-miR-16	CLIP-seq
MIRT1175532	hsa-miR-195	CLIP-seq
MIRT1175533	hsa-miR-200b	CLIP-seq
MIRT1175534	hsa-miR-200c	CLIP-seq
MIRT1175535	hsa-miR-214	CLIP-seq
MIRT1175536	hsa-miR-23a	CLIP-seq
MIRT1175537	hsa-miR-23b	CLIP-seq
MIRT1175538	hsa-miR-23c	CLIP-seq
MIRT1175539	hsa-miR-2682	CLIP-seq
MIRT1175540	hsa-miR-3152-5p	CLIP-seq
MIRT1175541	hsa-miR-3619-5p	CLIP-seq
MIRT1175542	hsa-miR-369-3p	CLIP-seq
MIRT1175543	hsa-miR-3921	CLIP-seq
MIRT1175544	hsa-miR-424	CLIP-seq
MIRT1175545	hsa-miR-429	CLIP-seq
MIRT1175546	hsa-miR-4303	CLIP-seq
MIRT1175547	hsa-miR-4468	CLIP-seq
MIRT1175548	hsa-miR-449c	CLIP-seq
MIRT1175549	hsa-miR-4514	CLIP-seq
MIRT1175550	hsa-miR-4653-5p	CLIP-seq
MIRT1175551	hsa-miR-4690-5p	CLIP-seq
MIRT1175552	hsa-miR-4692	CLIP-seq
MIRT1175553	hsa-miR-4717-3p	CLIP-seq
MIRT1175554	hsa-miR-4774-3p	CLIP-seq
MIRT1175555	hsa-miR-497	CLIP-seq
MIRT1175556	hsa-miR-577	CLIP-seq
MIRT1175557	hsa-miR-761	CLIP-seq
MIRT1175558	hsa-miR-1183	CLIP-seq
MIRT1175529	hsa-miR-15a	CLIP-seq
MIRT1175530	hsa-miR-15b	CLIP-seq
MIRT1175531	hsa-miR-16	CLIP-seq
MIRT1175532	hsa-miR-195	CLIP-seq
MIRT1175559	hsa-miR-197	CLIP-seq
MIRT1175533	hsa-miR-200b	CLIP-seq
MIRT1175534	hsa-miR-200c	CLIP-seq
MIRT1175535	hsa-miR-214	CLIP-seq
MIRT1175539	hsa-miR-2682	CLIP-seq
MIRT1175560	hsa-miR-300	CLIP-seq
MIRT1175561	hsa-miR-3127-3p	CLIP-seq
MIRT1175562	hsa-miR-3137	CLIP-seq
MIRT1175563	hsa-miR-361-3p	CLIP-seq
MIRT1175541	hsa-miR-3619-5p	CLIP-seq
MIRT1175564	hsa-miR-3679-3p	CLIP-seq
MIRT1175542	hsa-miR-369-3p	CLIP-seq
MIRT1175565	hsa-miR-374c	CLIP-seq
MIRT1175566	hsa-miR-381	CLIP-seq
MIRT1175543	hsa-miR-3921	CLIP-seq
MIRT1175567	hsa-miR-3924	CLIP-seq
MIRT1175544	hsa-miR-424	CLIP-seq
MIRT1175568	hsa-miR-4286	CLIP-seq
MIRT1175545	hsa-miR-429	CLIP-seq
MIRT1175546	hsa-miR-4303	CLIP-seq
MIRT1175569	hsa-miR-431	CLIP-seq
MIRT1175570	hsa-miR-4420	CLIP-seq
MIRT1175571	hsa-miR-4446-5p	CLIP-seq
MIRT1175547	hsa-miR-4468	CLIP-seq
MIRT1175548	hsa-miR-449c	CLIP-seq
MIRT1175549	hsa-miR-4514	CLIP-seq
MIRT1175572	hsa-miR-4539	CLIP-seq
MIRT1175550	hsa-miR-4653-5p	CLIP-seq
MIRT1175573	hsa-miR-4678	CLIP-seq
MIRT1175551	hsa-miR-4690-5p	CLIP-seq
MIRT1175552	hsa-miR-4692	CLIP-seq
MIRT1175574	hsa-miR-4712-3p	CLIP-seq
MIRT1175575	hsa-miR-4729	CLIP-seq
MIRT1175576	hsa-miR-4775	CLIP-seq
MIRT1175555	hsa-miR-497	CLIP-seq
MIRT1175577	hsa-miR-5096	CLIP-seq
MIRT1175578	hsa-miR-511	CLIP-seq
MIRT1175579	hsa-miR-548ac	CLIP-seq
MIRT1175580	hsa-miR-548ae	CLIP-seq
MIRT1175581	hsa-miR-548aj	CLIP-seq
MIRT1175582	hsa-miR-548am	CLIP-seq
MIRT1175583	hsa-miR-548d-3p	CLIP-seq
MIRT1175584	hsa-miR-548x	CLIP-seq
MIRT1175585	hsa-miR-548z	CLIP-seq
MIRT1175586	hsa-miR-569	CLIP-seq
MIRT1175556	hsa-miR-577	CLIP-seq
MIRT1175587	hsa-miR-580	CLIP-seq
MIRT1175588	hsa-miR-607	CLIP-seq
MIRT1175589	hsa-miR-624	CLIP-seq
MIRT1175590	hsa-miR-651	CLIP-seq
MIRT1175591	hsa-miR-655	CLIP-seq
MIRT1175557	hsa-miR-761	CLIP-seq
MIRT1175592	hsa-miR-876-3p	CLIP-seq
MIRT1175529	hsa-miR-15a	CLIP-seq
MIRT1175530	hsa-miR-15b	CLIP-seq
MIRT1175531	hsa-miR-16	CLIP-seq
MIRT1175532	hsa-miR-195	CLIP-seq
MIRT2050834	hsa-miR-204	CLIP-seq
MIRT2050835	hsa-miR-211	CLIP-seq
MIRT1175535	hsa-miR-214	CLIP-seq
MIRT1175536	hsa-miR-23a	CLIP-seq
MIRT1175537	hsa-miR-23b	CLIP-seq
MIRT1175538	hsa-miR-23c	CLIP-seq
MIRT1175539	hsa-miR-2682	CLIP-seq
MIRT2050836	hsa-miR-28-5p	CLIP-seq
MIRT1175560	hsa-miR-300	CLIP-seq
MIRT2050837	hsa-miR-3139	CLIP-seq
MIRT1175540	hsa-miR-3152-5p	CLIP-seq
MIRT2050838	hsa-miR-3158-3p	CLIP-seq
MIRT2050839	hsa-miR-3607-3p	CLIP-seq
MIRT1175541	hsa-miR-3619-5p	CLIP-seq
MIRT1175565	hsa-miR-374c	CLIP-seq
MIRT1175566	hsa-miR-381	CLIP-seq
MIRT1175543	hsa-miR-3921	CLIP-seq
MIRT2050840	hsa-miR-3974	CLIP-seq
MIRT1175544	hsa-miR-424	CLIP-seq
MIRT2050841	hsa-miR-4266	CLIP-seq
MIRT1175546	hsa-miR-4303	CLIP-seq
MIRT1175547	hsa-miR-4468	CLIP-seq
MIRT1175548	hsa-miR-449c	CLIP-seq
MIRT1175549	hsa-miR-4514	CLIP-seq
MIRT1175550	hsa-miR-4653-5p	CLIP-seq
MIRT1175551	hsa-miR-4690-5p	CLIP-seq
MIRT1175552	hsa-miR-4692	CLIP-seq
MIRT1175553	hsa-miR-4717-3p	CLIP-seq
MIRT2050842	hsa-miR-4755-5p	CLIP-seq
MIRT2050843	hsa-miR-4763-5p	CLIP-seq
MIRT1175554	hsa-miR-4774-3p	CLIP-seq
MIRT1175576	hsa-miR-4775	CLIP-seq
MIRT2050844	hsa-miR-483-3p	CLIP-seq
MIRT1175555	hsa-miR-497	CLIP-seq
MIRT2050845	hsa-miR-596	CLIP-seq
MIRT1175589	hsa-miR-624	CLIP-seq
MIRT1175590	hsa-miR-651	CLIP-seq
MIRT1175591	hsa-miR-655	CLIP-seq
MIRT2050846	hsa-miR-664	CLIP-seq
MIRT2050847	hsa-miR-668	CLIP-seq
MIRT2050848	hsa-miR-708	CLIP-seq
MIRT1175557	hsa-miR-761	CLIP-seq
MIRT2279907	hsa-miR-1179	CLIP-seq
MIRT2279908	hsa-miR-1206	CLIP-seq
MIRT2279909	hsa-miR-1226	CLIP-seq
MIRT2279910	hsa-miR-1236	CLIP-seq
MIRT2279911	hsa-miR-1279	CLIP-seq
MIRT2279912	hsa-miR-146a	CLIP-seq
MIRT2279913	hsa-miR-146b-5p	CLIP-seq
MIRT1175559	hsa-miR-197	CLIP-seq
MIRT1175533	hsa-miR-200b	CLIP-seq
MIRT1175534	hsa-miR-200c	CLIP-seq
MIRT2279914	hsa-miR-205	CLIP-seq
MIRT2279915	hsa-miR-22	CLIP-seq
MIRT1175539	hsa-miR-2682	CLIP-seq
MIRT2279916	hsa-miR-298	CLIP-seq
MIRT1175560	hsa-miR-300	CLIP-seq
MIRT2279917	hsa-miR-30a	CLIP-seq
MIRT2279918	hsa-miR-30b	CLIP-seq
MIRT2279919	hsa-miR-30c	CLIP-seq
MIRT2279920	hsa-miR-30d	CLIP-seq
MIRT2279921	hsa-miR-30e	CLIP-seq
MIRT1175561	hsa-miR-3127-3p	CLIP-seq
MIRT2279922	hsa-miR-3170	CLIP-seq
MIRT2279923	hsa-miR-3182	CLIP-seq
MIRT2279924	hsa-miR-339-5p	CLIP-seq
MIRT2279925	hsa-miR-342-3p	CLIP-seq
MIRT2279926	hsa-miR-3591-3p	CLIP-seq
MIRT2050839	hsa-miR-3607-3p	CLIP-seq
MIRT2279927	hsa-miR-3678-3p	CLIP-seq
MIRT1175564	hsa-miR-3679-3p	CLIP-seq
MIRT2279928	hsa-miR-3686	CLIP-seq
MIRT2279929	hsa-miR-3691-3p	CLIP-seq
MIRT2279930	hsa-miR-3692	CLIP-seq
MIRT1175542	hsa-miR-369-3p	CLIP-seq
MIRT1175565	hsa-miR-374c	CLIP-seq
MIRT2279931	hsa-miR-377	CLIP-seq
MIRT1175566	hsa-miR-381	CLIP-seq
MIRT2279932	hsa-miR-412	CLIP-seq
MIRT1175545	hsa-miR-429	CLIP-seq
MIRT2279933	hsa-miR-4433	CLIP-seq
MIRT2279934	hsa-miR-4436b-5p	CLIP-seq
MIRT1175571	hsa-miR-4446-5p	CLIP-seq
MIRT2279935	hsa-miR-4459	CLIP-seq
MIRT1175548	hsa-miR-449c	CLIP-seq
MIRT2279936	hsa-miR-450b-5p	CLIP-seq
MIRT1175549	hsa-miR-4514	CLIP-seq
MIRT2279937	hsa-miR-4653-3p	CLIP-seq
MIRT2279938	hsa-miR-4667-5p	CLIP-seq
MIRT1175551	hsa-miR-4690-5p	CLIP-seq
MIRT1175552	hsa-miR-4692	CLIP-seq
MIRT2279939	hsa-miR-4700-5p	CLIP-seq
MIRT2279940	hsa-miR-4749-3p	CLIP-seq
MIRT2279941	hsa-miR-4768-3p	CLIP-seq
MIRT2279942	hsa-miR-4777-3p	CLIP-seq
MIRT2279943	hsa-miR-4797-5p	CLIP-seq
MIRT2279944	hsa-miR-490-3p	CLIP-seq
MIRT2279945	hsa-miR-490-5p	CLIP-seq
MIRT2279946	hsa-miR-507	CLIP-seq
MIRT2279947	hsa-miR-557	CLIP-seq
MIRT1175556	hsa-miR-577	CLIP-seq
MIRT2279948	hsa-miR-579	CLIP-seq
MIRT2279949	hsa-miR-589	CLIP-seq
MIRT2279950	hsa-miR-603	CLIP-seq
MIRT1175589	hsa-miR-624	CLIP-seq
MIRT2279951	hsa-miR-637	CLIP-seq
MIRT1175591	hsa-miR-655	CLIP-seq
MIRT2279952	hsa-miR-759	CLIP-seq
MIRT2279953	hsa-miR-888	CLIP-seq
MIRT2279954	hsa-miR-891b	CLIP-seq
MIRT2050834	hsa-miR-204	CLIP-seq
MIRT2050835	hsa-miR-211	CLIP-seq
MIRT1175551	hsa-miR-4690-5p	CLIP-seq
MIRT2050842	hsa-miR-4755-5p	CLIP-seq
MIRT2578415	hsa-miR-106a	CLIP-seq
MIRT2578416	hsa-miR-106b	CLIP-seq
MIRT1175558	hsa-miR-1183	CLIP-seq
MIRT2578417	hsa-miR-1284	CLIP-seq
MIRT2578418	hsa-miR-1290	CLIP-seq
MIRT1175529	hsa-miR-15a	CLIP-seq
MIRT1175530	hsa-miR-15b	CLIP-seq
MIRT1175531	hsa-miR-16	CLIP-seq
MIRT2578419	hsa-miR-17	CLIP-seq
MIRT2578420	hsa-miR-1913	CLIP-seq
MIRT1175532	hsa-miR-195	CLIP-seq
MIRT1175533	hsa-miR-200b	CLIP-seq
MIRT1175534	hsa-miR-200c	CLIP-seq
MIRT2050834	hsa-miR-204	CLIP-seq
MIRT2578421	hsa-miR-20a	CLIP-seq
MIRT2578422	hsa-miR-20b	CLIP-seq
MIRT2050835	hsa-miR-211	CLIP-seq
MIRT1175535	hsa-miR-214	CLIP-seq
MIRT1175536	hsa-miR-23a	CLIP-seq
MIRT1175537	hsa-miR-23b	CLIP-seq
MIRT1175538	hsa-miR-23c	CLIP-seq
MIRT1175539	hsa-miR-2682	CLIP-seq
MIRT2050836	hsa-miR-28-5p	CLIP-seq
MIRT1175560	hsa-miR-300	CLIP-seq
MIRT1175562	hsa-miR-3137	CLIP-seq
MIRT2050837	hsa-miR-3139	CLIP-seq
MIRT1175540	hsa-miR-3152-5p	CLIP-seq
MIRT2578423	hsa-miR-3156-5p	CLIP-seq
MIRT2578424	hsa-miR-324-3p	CLIP-seq
MIRT2050839	hsa-miR-3607-3p	CLIP-seq
MIRT2578425	hsa-miR-3609	CLIP-seq
MIRT1175563	hsa-miR-361-3p	CLIP-seq
MIRT1175541	hsa-miR-3619-5p	CLIP-seq
MIRT2578426	hsa-miR-3620	CLIP-seq
MIRT2578427	hsa-miR-3647-3p	CLIP-seq
MIRT2578428	hsa-miR-3653	CLIP-seq
MIRT2578429	hsa-miR-3658	CLIP-seq
MIRT2578430	hsa-miR-3663-5p	CLIP-seq
MIRT1175564	hsa-miR-3679-3p	CLIP-seq
MIRT1175565	hsa-miR-374c	CLIP-seq
MIRT2279931	hsa-miR-377	CLIP-seq
MIRT1175566	hsa-miR-381	CLIP-seq
MIRT1175543	hsa-miR-3921	CLIP-seq
MIRT1175544	hsa-miR-424	CLIP-seq
MIRT2050841	hsa-miR-4266	CLIP-seq
MIRT2578431	hsa-miR-4282	CLIP-seq
MIRT1175568	hsa-miR-4286	CLIP-seq
MIRT1175545	hsa-miR-429	CLIP-seq
MIRT1175546	hsa-miR-4303	CLIP-seq
MIRT1175569	hsa-miR-431	CLIP-seq
MIRT2578432	hsa-miR-4437	CLIP-seq
MIRT1175571	hsa-miR-4446-5p	CLIP-seq
MIRT1175547	hsa-miR-4468	CLIP-seq
MIRT1175548	hsa-miR-449c	CLIP-seq
MIRT2578433	hsa-miR-4509	CLIP-seq
MIRT1175549	hsa-miR-4514	CLIP-seq
MIRT1175572	hsa-miR-4539	CLIP-seq
MIRT1175550	hsa-miR-4653-5p	CLIP-seq
MIRT2578434	hsa-miR-4674	CLIP-seq
MIRT1175573	hsa-miR-4678	CLIP-seq
MIRT1175551	hsa-miR-4690-5p	CLIP-seq
MIRT1175552	hsa-miR-4692	CLIP-seq
MIRT2578435	hsa-miR-4699-3p	CLIP-seq
MIRT1175553	hsa-miR-4717-3p	CLIP-seq
MIRT2578436	hsa-miR-4744	CLIP-seq
MIRT2050842	hsa-miR-4755-5p	CLIP-seq
MIRT2050843	hsa-miR-4763-5p	CLIP-seq
MIRT2578437	hsa-miR-4766-3p	CLIP-seq
MIRT1175554	hsa-miR-4774-3p	CLIP-seq
MIRT1175576	hsa-miR-4775	CLIP-seq
MIRT2578438	hsa-miR-4796-3p	CLIP-seq
MIRT2578439	hsa-miR-485-3p	CLIP-seq
MIRT1175555	hsa-miR-497	CLIP-seq
MIRT1175578	hsa-miR-511	CLIP-seq
MIRT2578440	hsa-miR-513a-3p	CLIP-seq
MIRT2578441	hsa-miR-513b	CLIP-seq
MIRT2578442	hsa-miR-519d	CLIP-seq
MIRT2578443	hsa-miR-548a-3p	CLIP-seq
MIRT1175580	hsa-miR-548ae	CLIP-seq
MIRT2578444	hsa-miR-548ah	CLIP-seq
MIRT1175581	hsa-miR-548aj	CLIP-seq
MIRT1175582	hsa-miR-548am	CLIP-seq
MIRT2578445	hsa-miR-548an	CLIP-seq
MIRT2578446	hsa-miR-548c-3p	CLIP-seq
MIRT2578447	hsa-miR-548e	CLIP-seq
MIRT2578448	hsa-miR-548f	CLIP-seq
MIRT2578449	hsa-miR-548g	CLIP-seq
MIRT2578450	hsa-miR-548p	CLIP-seq
MIRT1175584	hsa-miR-548x	CLIP-seq
MIRT2279948	hsa-miR-579	CLIP-seq
MIRT2050845	hsa-miR-596	CLIP-seq
MIRT2279950	hsa-miR-603	CLIP-seq
MIRT2578451	hsa-miR-623	CLIP-seq
MIRT1175589	hsa-miR-624	CLIP-seq
MIRT1175590	hsa-miR-651	CLIP-seq
MIRT1175591	hsa-miR-655	CLIP-seq
MIRT2050846	hsa-miR-664	CLIP-seq
MIRT2050848	hsa-miR-708	CLIP-seq
MIRT1175557	hsa-miR-761	CLIP-seq
MIRT2578452	hsa-miR-93	CLIP-seq
MIRT2578415	hsa-miR-106a	CLIP-seq
MIRT2578416	hsa-miR-106b	CLIP-seq
MIRT1175558	hsa-miR-1183	CLIP-seq
MIRT2578418	hsa-miR-1290	CLIP-seq
MIRT1175529	hsa-miR-15a	CLIP-seq
MIRT1175530	hsa-miR-15b	CLIP-seq
MIRT1175531	hsa-miR-16	CLIP-seq
MIRT2578419	hsa-miR-17	CLIP-seq
MIRT1175532	hsa-miR-195	CLIP-seq
MIRT1175533	hsa-miR-200b	CLIP-seq
MIRT1175534	hsa-miR-200c	CLIP-seq
MIRT2050834	hsa-miR-204	CLIP-seq
MIRT2578421	hsa-miR-20a	CLIP-seq
MIRT2578422	hsa-miR-20b	CLIP-seq
MIRT2050835	hsa-miR-211	CLIP-seq
MIRT1175535	hsa-miR-214	CLIP-seq
MIRT1175562	hsa-miR-3137	CLIP-seq
MIRT2578425	hsa-miR-3609	CLIP-seq
MIRT1175541	hsa-miR-3619-5p	CLIP-seq
MIRT2578427	hsa-miR-3647-3p	CLIP-seq
MIRT2578428	hsa-miR-3653	CLIP-seq
MIRT2578429	hsa-miR-3658	CLIP-seq
MIRT2578430	hsa-miR-3663-5p	CLIP-seq
MIRT1175543	hsa-miR-3921	CLIP-seq
MIRT1175544	hsa-miR-424	CLIP-seq
MIRT2578431	hsa-miR-4282	CLIP-seq
MIRT1175545	hsa-miR-429	CLIP-seq
MIRT1175546	hsa-miR-4303	CLIP-seq
MIRT1175569	hsa-miR-431	CLIP-seq
MIRT2578432	hsa-miR-4437	CLIP-seq
MIRT1175571	hsa-miR-4446-5p	CLIP-seq
MIRT1175547	hsa-miR-4468	CLIP-seq
MIRT2578433	hsa-miR-4509	CLIP-seq
MIRT1175550	hsa-miR-4653-5p	CLIP-seq
MIRT2578434	hsa-miR-4674	CLIP-seq
MIRT1175573	hsa-miR-4678	CLIP-seq
MIRT1175551	hsa-miR-4690-5p	CLIP-seq
MIRT2578435	hsa-miR-4699-3p	CLIP-seq
MIRT2578436	hsa-miR-4744	CLIP-seq
MIRT2050842	hsa-miR-4755-5p	CLIP-seq
MIRT2578437	hsa-miR-4766-3p	CLIP-seq
MIRT2578438	hsa-miR-4796-3p	CLIP-seq
MIRT2578439	hsa-miR-485-3p	CLIP-seq
MIRT1175555	hsa-miR-497	CLIP-seq
MIRT1175578	hsa-miR-511	CLIP-seq
MIRT2578440	hsa-miR-513a-3p	CLIP-seq
MIRT2578441	hsa-miR-513b	CLIP-seq
MIRT2578442	hsa-miR-519d	CLIP-seq
MIRT2578443	hsa-miR-548a-3p	CLIP-seq
MIRT1175580	hsa-miR-548ae	CLIP-seq
MIRT2578444	hsa-miR-548ah	CLIP-seq
MIRT1175581	hsa-miR-548aj	CLIP-seq
MIRT1175582	hsa-miR-548am	CLIP-seq
MIRT2578445	hsa-miR-548an	CLIP-seq
MIRT2578447	hsa-miR-548e	CLIP-seq
MIRT2578448	hsa-miR-548f	CLIP-seq
MIRT2578449	hsa-miR-548g	CLIP-seq
MIRT2578450	hsa-miR-548p	CLIP-seq
MIRT1175584	hsa-miR-548x	CLIP-seq
MIRT2578451	hsa-miR-623	CLIP-seq
MIRT2050846	hsa-miR-664	CLIP-seq
MIRT1175557	hsa-miR-761	CLIP-seq
MIRT2578452	hsa-miR-93	CLIP-seq
MIRT2050842	hsa-miR-4755-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (36)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000407	Component	Phagophore assembly site	IBA
GO:0000407	Component	Phagophore assembly site	IEA
GO:0005515	Function	Protein binding	IPI	19250911, 19427866, 19822672, 20010802, 20368287, 20417604, 20562859, 20808283, 24879152, 25416956, 26871637, 29568061, 30824926, 32296183, 33961781, 34524948
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IDA	21296869
GO:0005758	Component	Mitochondrial intermembrane space	IEA
GO:0005764	Component	Lysosome	IEA
GO:0005770	Component	Late endosome	IEA
GO:0005770	Component	Late endosome	ISS
GO:0005776	Component	Autophagosome	IEA
GO:0005776	Component	Autophagosome	IEA
GO:0005776	Component	Autophagosome	ISS
GO:0005778	Component	Peroxisomal membrane	IEA
GO:0005778	Component	Peroxisomal membrane	TAS
GO:0005829	Component	Cytosol	IDA	19250911
GO:0008270	Function	Zinc ion binding	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016236	Process	Macroautophagy	IBA
GO:0016236	Process	Macroautophagy	IDA	19250911
GO:0016604	Component	Nuclear body	IDA
GO:0030500	Process	Regulation of bone mineralization	IEA
GO:0030500	Process	Regulation of bone mineralization	ISS
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031430	Component	M band	IEA
GO:0032872	Process	Regulation of stress-activated MAPK cascade	IEA
GO:0032872	Process	Regulation of stress-activated MAPK cascade	ISS
GO:0043130	Function	Ubiquitin binding	IBA
GO:0043130	Function	Ubiquitin binding	IDA	19427866
GO:0043235	Component	Receptor complex	IDA	19250911
GO:0045668	Process	Negative regulation of osteoblast differentiation	IEA
GO:0045668	Process	Negative regulation of osteoblast differentiation	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0051019	Function	Mitogen-activated protein kinase binding	IEA
GO:0051019	Function	Mitogen-activated protein kinase binding	ISS
GO:0070013	Component	Intracellular organelle lumen	IEA

Other IDs

• MIM: 166945
• HGNC: 6746
• e!Ensembl: ENSG00000188554

Protein

• UniProt ID: Q14596
• Protein name: Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
• Protein function: Ubiquitin-binding autophagy adapter that participates in different processes including host defense or intracellular homeostasis (PubMed:24692539, PubMed:33577621). Possesses a double function during the selective autophagy by acting as a shuttl
• PDB: 1WJ6 , 2BKF , 2CP8 , 2G4S , 2L8J , 2MGW , 2MJ5 , 4OLE
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00564	PB1	4 → 85	PB1 domain	Domain
  PF00569	ZZ	212 → 253	Zinc finger, ZZ type	Domain
  PF16158	N_BRCA1_IG	379 → 478	Ig-like domain from next to BRCA1 gene	Domain

• Sequence:

  MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
  QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
  LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
  LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
  EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
  EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
  LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
  LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
  FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
  VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
  KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
  AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
  VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
  ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
  TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
  FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
  WYSQRY

• Sequence length: 966

Pathways

KEGG Pathway	Reactome Pathway
Mitophagy - animal	Pexophagy
Autophagy - animal

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Thyroid cancer, nonmedullary, 1	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (20)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Asthma	Asthma	BEFREE	20808283		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	11508855		★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	14961556		★☆☆☆☆ Found in Text Mining only
Dentatorubral-Pallidoluysian Atrophy	Dentatorubral Pallidoluysian Atrophy	BEFREE	30153072		★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathies	Diabetic neuropathy	Pubtator	36465646	Associate	★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down syndrome	Pubtator	31714914	Stimulate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	29718398, 37097629	Associate	★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	32664164	Associate	★☆☆☆☆ Found in Text Mining only
Inclusion Body Myopathy, Sporadic	Inclusion body myopathy	BEFREE	24879152		★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	29940753		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	11508855		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	14961556		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	31297862		★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	25043814		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	24692539	Associate	★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	25412696		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	25043814		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	14961556		★☆☆☆☆ Found in Text Mining only
Pancreatic Ductal Adenocarcinoma	Pancreatic adenocarcinoma	BEFREE	30153072		★☆☆☆☆ Found in Text Mining only
Ventricular Remodeling	Ventricular remodeling	Pubtator	32664164	Stimulate	★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

USP30 2 shared pathwaysMitophagy - animal, Pexophagy Related via 2 shared pathways including Mitophagy - animal, Pexophagy. OPTN 2 shared pathwaysMitophagy - animal, Autophagy - animal Related via 2 shared pathways including Mitophagy - animal, Autophagy - animal. CALCOCO2 2 shared pathwaysMitophagy - animal, Autophagy - animal Related via 2 shared pathways including Mitophagy - animal, Autophagy - animal. ATG9B 2 shared pathwaysMitophagy - animal, Autophagy - animal Related via 2 shared pathways including Mitophagy - animal, Autophagy - animal. AMBRA1 2 shared pathwaysMitophagy - animal, Autophagy - animal Related via 2 shared pathways including Mitophagy - animal, Autophagy - animal.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
USP30	0	[]	2	["Mitophagy - animal","Pexophagy"]	0	[]
OPTN	0	[]	2	["Mitophagy - animal","Autophagy - animal"]	0	[]
CALCOCO2	0	[]	2	["Mitophagy - animal","Autophagy - animal"]	0	[]
ATG9B	0	[]	2	["Mitophagy - animal","Autophagy - animal"]	0	[]
AMBRA1	0	[]	2	["Mitophagy - animal","Autophagy - animal"]	0	[]

Diseases Linked via Similar Genes

Alzheimer disease Linked via 1 of 5 related genesOPTN Amyotrophic lateral sclerosis Linked via 1 of 5 related genesOPTN Dementia Linked via 1 of 5 related genesOPTN Frontotemporal dementia Linked via 1 of 5 related genesOPTN Glaucoma Linked via 1 of 5 related genesOPTN

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Alzheimer disease	1	["OPTN"]
Amyotrophic lateral sclerosis	1	["OPTN"]
Dementia	1	["OPTN"]
Frontotemporal dementia	1	["OPTN"]
Glaucoma	1	["OPTN"]