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Gene Gene information from NCBI Gene database.
Entrez ID 8775
Gene name NSF attachment protein alpha
Gene symbol NAPA
Synonyms (NCBI Gene)
SNAPA
Chromosome 19
Chromosome location 19q13.32-q13.33
Summary This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the
miRNA miRNA information provided by mirtarbase database.
263 Show/Hide all (263)
miRTarBase ID miRNA Experiments Reference
MIRT734163 hsa-miR-1290 ImmunofluorescenceLuciferase reporter assayqRT-PCRWestern blotting 32319530
MIRT1173765 hsa-miR-1207-3p CLIP-seq
MIRT1173766 hsa-miR-1275 CLIP-seq
MIRT1173767 hsa-miR-1303 CLIP-seq
MIRT1173768 hsa-miR-214 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
38 Show/Hide all (38)
GO ID Ontology Definition Evidence Reference
GO:0000149 Function SNARE binding IEA
GO:0000149 Function SNARE binding ISS
GO:0005483 Function Soluble NSF attachment protein activity IBA
GO:0005515 Function Protein binding IPI 15029241, 15272311, 15322554, 16189514, 16354670, 20562859, 30833792, 32814053, 33961781, 35271311
GO:0005829 Component Cytosol TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603215 7641 ENSG00000105402
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P54920
Protein name Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)
Protein function Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14938 SNAP 8 → 288 Domain
Sequence
Sequence length 295
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Synaptic vesicle cycle COPII-mediated vesicle transport
  Golgi Associated Vesicle Biogenesis
  COPI-mediated anterograde transport
  COPI-dependent Golgi-to-ER retrograde traffic
  Intra-Golgi traffic
  Retrograde transport at the Trans-Golgi-Network