KPNB1 (karyopherin subunit beta 1)

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Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 3837
• Gene name: Karyopherin subunit beta 1
• Gene symbol: KPNB1
• Synonyms (NCBI Gene): IMB1, IPO1, IPOB, Impnb, NTF97
• Chromosome: 17
• Chromosome location: 17q21.32
• Summary: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a het

miRNA Show/Hide all (609)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049219	hsa-miR-92a-3p	CLASH	23622248
MIRT047765	hsa-miR-7-5p	CLASH	23622248
MIRT047236	hsa-miR-181b-5p	CLASH	23622248
MIRT046618	hsa-miR-222-3p	CLASH	23622248
MIRT046618	hsa-miR-222-3p	CLASH	23622248
MIRT046618	hsa-miR-222-3p	CLASH	23622248
MIRT046096	hsa-miR-125b-5p	CLASH	23622248
MIRT045863	hsa-miR-128-3p	CLASH	23622248
MIRT045512	hsa-miR-149-5p	CLASH	23622248
MIRT045512	hsa-miR-149-5p	CLASH	23622248
MIRT045512	hsa-miR-149-5p	CLASH	23622248
MIRT044704	hsa-miR-320a	CLASH	23622248
MIRT041827	hsa-miR-484	CLASH	23622248
MIRT039764	hsa-miR-615-3p	CLASH	23622248
MIRT039019	hsa-miR-766-3p	CLASH	23622248
MIRT037877	hsa-miR-455-3p	CLASH	23622248
MIRT037560	hsa-miR-744-5p	CLASH	23622248
MIRT037153	hsa-miR-877-3p	CLASH	23622248
MIRT037153	hsa-miR-877-3p	CLASH	23622248
MIRT037153	hsa-miR-877-3p	CLASH	23622248
MIRT036355	hsa-miR-1229-3p	CLASH	23622248
MIRT036250	hsa-miR-1236-3p	CLASH	23622248
MIRT036147	hsa-miR-1296-5p	CLASH	23622248
MIRT438722	hsa-miR-30d-5p	Luciferase reporter assay, qRT-PCR, Western blot	24132643
MIRT438722	hsa-miR-30d-5p	Luciferase reporter assay, qRT-PCR, Western blot	24132643
MIRT438722	hsa-miR-30d-5p	Luciferase reporter assay, qRT-PCR, Western blot	24132643
MIRT438722	hsa-miR-30d-5p	Luciferase reporter assay, qRT-PCR, Western blot	24132643
MIRT497826	hsa-miR-4484	PAR-CLIP	22291592
MIRT497825	hsa-miR-524-3p	PAR-CLIP	22291592
MIRT497824	hsa-miR-525-3p	PAR-CLIP	22291592
MIRT497823	hsa-miR-4496	PAR-CLIP	22291592
MIRT497822	hsa-miR-566	PAR-CLIP	22291592
MIRT497826	hsa-miR-4484	PAR-CLIP	22291592
MIRT497825	hsa-miR-524-3p	PAR-CLIP	22291592
MIRT497824	hsa-miR-525-3p	PAR-CLIP	22291592
MIRT497823	hsa-miR-4496	PAR-CLIP	22291592
MIRT497822	hsa-miR-566	PAR-CLIP	22291592
MIRT1100388	hsa-miR-128	CLIP-seq
MIRT1100389	hsa-miR-129-5p	CLIP-seq
MIRT1100390	hsa-miR-1305	CLIP-seq
MIRT1100391	hsa-miR-1323	CLIP-seq
MIRT1100392	hsa-miR-140-3p	CLIP-seq
MIRT1100393	hsa-miR-145	CLIP-seq
MIRT1100394	hsa-miR-147	CLIP-seq
MIRT1100395	hsa-miR-1470	CLIP-seq
MIRT1100396	hsa-miR-148a	CLIP-seq
MIRT1100397	hsa-miR-148b	CLIP-seq
MIRT1100398	hsa-miR-152	CLIP-seq
MIRT1100399	hsa-miR-154	CLIP-seq
MIRT1100400	hsa-miR-181a	CLIP-seq
MIRT1100401	hsa-miR-181b	CLIP-seq
MIRT1100402	hsa-miR-181c	CLIP-seq
MIRT1100403	hsa-miR-181d	CLIP-seq
MIRT1100404	hsa-miR-1825	CLIP-seq
MIRT1100405	hsa-miR-194	CLIP-seq
MIRT1100406	hsa-miR-1973	CLIP-seq
MIRT1100407	hsa-miR-199a-5p	CLIP-seq
MIRT1100408	hsa-miR-199b-5p	CLIP-seq
MIRT1100409	hsa-miR-203	CLIP-seq
MIRT1100410	hsa-miR-2052	CLIP-seq
MIRT1100411	hsa-miR-2113	CLIP-seq
MIRT1100412	hsa-miR-2114	CLIP-seq
MIRT1100413	hsa-miR-218	CLIP-seq
MIRT1100414	hsa-miR-27a	CLIP-seq
MIRT1100415	hsa-miR-27b	CLIP-seq
MIRT1100416	hsa-miR-28-5p	CLIP-seq
MIRT1100417	hsa-miR-297	CLIP-seq
MIRT1100418	hsa-miR-29a	CLIP-seq
MIRT1100419	hsa-miR-29b	CLIP-seq
MIRT1100420	hsa-miR-29c	CLIP-seq
MIRT1100421	hsa-miR-300	CLIP-seq
MIRT1100422	hsa-miR-3064-3p	CLIP-seq
MIRT1100423	hsa-miR-3065-5p	CLIP-seq
MIRT1100424	hsa-miR-3130-5p	CLIP-seq
MIRT1100425	hsa-miR-3139	CLIP-seq
MIRT1100426	hsa-miR-3148	CLIP-seq
MIRT1100427	hsa-miR-3153	CLIP-seq
MIRT1100428	hsa-miR-3180-5p	CLIP-seq
MIRT1100429	hsa-miR-3192	CLIP-seq
MIRT1100430	hsa-miR-330-3p	CLIP-seq
MIRT1100431	hsa-miR-3607-3p	CLIP-seq
MIRT1100432	hsa-miR-361-3p	CLIP-seq
MIRT1100433	hsa-miR-3616-5p	CLIP-seq
MIRT1100434	hsa-miR-3647-5p	CLIP-seq
MIRT1100435	hsa-miR-377	CLIP-seq
MIRT1100436	hsa-miR-381	CLIP-seq
MIRT1100437	hsa-miR-3940-5p	CLIP-seq
MIRT1100438	hsa-miR-4256	CLIP-seq
MIRT1100439	hsa-miR-4262	CLIP-seq
MIRT1100440	hsa-miR-4286	CLIP-seq
MIRT1100441	hsa-miR-4291	CLIP-seq
MIRT1100442	hsa-miR-4302	CLIP-seq
MIRT1100443	hsa-miR-4310	CLIP-seq
MIRT1100444	hsa-miR-4314	CLIP-seq
MIRT1100445	hsa-miR-4330	CLIP-seq
MIRT1100446	hsa-miR-4426	CLIP-seq
MIRT1100447	hsa-miR-4433	CLIP-seq
MIRT1100448	hsa-miR-4447	CLIP-seq
MIRT1100449	hsa-miR-4459	CLIP-seq
MIRT1100450	hsa-miR-4472	CLIP-seq
MIRT1100451	hsa-miR-4482	CLIP-seq
MIRT1100452	hsa-miR-4488	CLIP-seq
MIRT1100453	hsa-miR-4494	CLIP-seq
MIRT1100454	hsa-miR-4507	CLIP-seq
MIRT1100455	hsa-miR-450b-5p	CLIP-seq
MIRT1100456	hsa-miR-4520a-5p	CLIP-seq
MIRT1100457	hsa-miR-4520b-5p	CLIP-seq
MIRT1100458	hsa-miR-4646-5p	CLIP-seq
MIRT1100459	hsa-miR-4647	CLIP-seq
MIRT1100460	hsa-miR-4662b	CLIP-seq
MIRT1100461	hsa-miR-4667-3p	CLIP-seq
MIRT1100462	hsa-miR-4667-5p	CLIP-seq
MIRT1100463	hsa-miR-4668-3p	CLIP-seq
MIRT1100464	hsa-miR-4668-5p	CLIP-seq
MIRT1100465	hsa-miR-4670-3p	CLIP-seq
MIRT1100466	hsa-miR-4697-3p	CLIP-seq
MIRT1100467	hsa-miR-4697-5p	CLIP-seq
MIRT1100468	hsa-miR-4700-5p	CLIP-seq
MIRT1100469	hsa-miR-4711-5p	CLIP-seq
MIRT1100470	hsa-miR-4713-5p	CLIP-seq
MIRT1100471	hsa-miR-4729	CLIP-seq
MIRT1100472	hsa-miR-4738-3p	CLIP-seq
MIRT1100473	hsa-miR-4762-3p	CLIP-seq
MIRT1100474	hsa-miR-4768-3p	CLIP-seq
MIRT1100475	hsa-miR-4772-5p	CLIP-seq
MIRT1100476	hsa-miR-4795-3p	CLIP-seq
MIRT1100477	hsa-miR-483-3p	CLIP-seq
MIRT1100478	hsa-miR-499a-5p	CLIP-seq
MIRT1100479	hsa-miR-513a-3p	CLIP-seq
MIRT1100480	hsa-miR-513a-5p	CLIP-seq
MIRT1100481	hsa-miR-520f	CLIP-seq
MIRT1100482	hsa-miR-543	CLIP-seq
MIRT1100483	hsa-miR-548c-3p	CLIP-seq
MIRT1100484	hsa-miR-548o	CLIP-seq
MIRT1100485	hsa-miR-567	CLIP-seq
MIRT1100486	hsa-miR-568	CLIP-seq
MIRT1100487	hsa-miR-573	CLIP-seq
MIRT1100488	hsa-miR-584	CLIP-seq
MIRT1100489	hsa-miR-591	CLIP-seq
MIRT1100490	hsa-miR-599	CLIP-seq
MIRT1100491	hsa-miR-603	CLIP-seq
MIRT1100492	hsa-miR-607	CLIP-seq
MIRT1100493	hsa-miR-614	CLIP-seq
MIRT1100494	hsa-miR-615-5p	CLIP-seq
MIRT1100495	hsa-miR-637	CLIP-seq
MIRT1100496	hsa-miR-656	CLIP-seq
MIRT1100497	hsa-miR-659	CLIP-seq
MIRT1100498	hsa-miR-708	CLIP-seq
MIRT1100411	hsa-miR-2113	CLIP-seq
MIRT2027329	hsa-miR-101	CLIP-seq
MIRT2027330	hsa-miR-1207-5p	CLIP-seq
MIRT2027331	hsa-miR-1237	CLIP-seq
MIRT2027332	hsa-miR-1248	CLIP-seq
MIRT2027333	hsa-miR-1290	CLIP-seq
MIRT1100389	hsa-miR-129-5p	CLIP-seq
MIRT1100390	hsa-miR-1305	CLIP-seq
MIRT2027334	hsa-miR-136	CLIP-seq
MIRT1100392	hsa-miR-140-3p	CLIP-seq
MIRT2027335	hsa-miR-144	CLIP-seq
MIRT1100395	hsa-miR-1470	CLIP-seq
MIRT1100396	hsa-miR-148a	CLIP-seq
MIRT1100397	hsa-miR-148b	CLIP-seq
MIRT1100398	hsa-miR-152	CLIP-seq
MIRT1100400	hsa-miR-181a	CLIP-seq
MIRT1100401	hsa-miR-181b	CLIP-seq
MIRT1100402	hsa-miR-181c	CLIP-seq
MIRT1100403	hsa-miR-181d	CLIP-seq
MIRT1100406	hsa-miR-1973	CLIP-seq
MIRT2027336	hsa-miR-199a-3p	CLIP-seq
MIRT2027337	hsa-miR-199b-3p	CLIP-seq
MIRT1100410	hsa-miR-2052	CLIP-seq
MIRT1100411	hsa-miR-2113	CLIP-seq
MIRT1100412	hsa-miR-2114	CLIP-seq
MIRT1100413	hsa-miR-218	CLIP-seq
MIRT1100416	hsa-miR-28-5p	CLIP-seq
MIRT1100418	hsa-miR-29a	CLIP-seq
MIRT1100419	hsa-miR-29b	CLIP-seq
MIRT1100420	hsa-miR-29c	CLIP-seq
MIRT1100421	hsa-miR-300	CLIP-seq
MIRT1100422	hsa-miR-3064-3p	CLIP-seq
MIRT1100423	hsa-miR-3065-5p	CLIP-seq
MIRT2027338	hsa-miR-31	CLIP-seq
MIRT2027339	hsa-miR-3128	CLIP-seq
MIRT2027340	hsa-miR-3129-5p	CLIP-seq
MIRT1100424	hsa-miR-3130-5p	CLIP-seq
MIRT1100425	hsa-miR-3139	CLIP-seq
MIRT1100426	hsa-miR-3148	CLIP-seq
MIRT1100427	hsa-miR-3153	CLIP-seq
MIRT2027341	hsa-miR-3183	CLIP-seq
MIRT1100429	hsa-miR-3192	CLIP-seq
MIRT1100430	hsa-miR-330-3p	CLIP-seq
MIRT1100432	hsa-miR-361-3p	CLIP-seq
MIRT2027342	hsa-miR-361-5p	CLIP-seq
MIRT2027343	hsa-miR-3650	CLIP-seq
MIRT2027344	hsa-miR-3688-5p	CLIP-seq
MIRT1100436	hsa-miR-381	CLIP-seq
MIRT1100437	hsa-miR-3940-5p	CLIP-seq
MIRT1100438	hsa-miR-4256	CLIP-seq
MIRT1100439	hsa-miR-4262	CLIP-seq
MIRT2027345	hsa-miR-4279	CLIP-seq
MIRT1100440	hsa-miR-4286	CLIP-seq
MIRT1100441	hsa-miR-4291	CLIP-seq
MIRT1100442	hsa-miR-4302	CLIP-seq
MIRT1100443	hsa-miR-4310	CLIP-seq
MIRT1100444	hsa-miR-4314	CLIP-seq
MIRT1100446	hsa-miR-4426	CLIP-seq
MIRT1100447	hsa-miR-4433	CLIP-seq
MIRT2027346	hsa-miR-4446-5p	CLIP-seq
MIRT1100449	hsa-miR-4459	CLIP-seq
MIRT2027347	hsa-miR-4467	CLIP-seq
MIRT2027348	hsa-miR-4470	CLIP-seq
MIRT1100451	hsa-miR-4482	CLIP-seq
MIRT1100452	hsa-miR-4488	CLIP-seq
MIRT1100453	hsa-miR-4494	CLIP-seq
MIRT1100454	hsa-miR-4507	CLIP-seq
MIRT2027349	hsa-miR-4645-5p	CLIP-seq
MIRT1100458	hsa-miR-4646-5p	CLIP-seq
MIRT1100459	hsa-miR-4647	CLIP-seq
MIRT1100460	hsa-miR-4662b	CLIP-seq
MIRT1100461	hsa-miR-4667-3p	CLIP-seq
MIRT1100462	hsa-miR-4667-5p	CLIP-seq
MIRT1100464	hsa-miR-4668-5p	CLIP-seq
MIRT1100465	hsa-miR-4670-3p	CLIP-seq
MIRT2027350	hsa-miR-4673	CLIP-seq
MIRT1100466	hsa-miR-4697-3p	CLIP-seq
MIRT1100467	hsa-miR-4697-5p	CLIP-seq
MIRT1100468	hsa-miR-4700-5p	CLIP-seq
MIRT1100469	hsa-miR-4711-5p	CLIP-seq
MIRT1100470	hsa-miR-4713-5p	CLIP-seq
MIRT2027351	hsa-miR-4723-3p	CLIP-seq
MIRT2027352	hsa-miR-4725-5p	CLIP-seq
MIRT1100471	hsa-miR-4729	CLIP-seq
MIRT2027353	hsa-miR-4730	CLIP-seq
MIRT2027354	hsa-miR-4736	CLIP-seq
MIRT2027355	hsa-miR-4753-3p	CLIP-seq
MIRT2027356	hsa-miR-4755-5p	CLIP-seq
MIRT1100473	hsa-miR-4762-3p	CLIP-seq
MIRT2027357	hsa-miR-4763-3p	CLIP-seq
MIRT2027358	hsa-miR-4764-3p	CLIP-seq
MIRT1100474	hsa-miR-4768-3p	CLIP-seq
MIRT2027359	hsa-miR-4768-5p	CLIP-seq
MIRT1100475	hsa-miR-4772-5p	CLIP-seq
MIRT2027360	hsa-miR-4797-3p	CLIP-seq
MIRT1100477	hsa-miR-483-3p	CLIP-seq
MIRT1100478	hsa-miR-499a-5p	CLIP-seq
MIRT2027361	hsa-miR-504	CLIP-seq
MIRT1100479	hsa-miR-513a-3p	CLIP-seq
MIRT1100481	hsa-miR-520f	CLIP-seq
MIRT2027362	hsa-miR-522	CLIP-seq
MIRT1100482	hsa-miR-543	CLIP-seq
MIRT2027363	hsa-miR-548m	CLIP-seq
MIRT2027364	hsa-miR-548p	CLIP-seq
MIRT1100488	hsa-miR-584	CLIP-seq
MIRT1100489	hsa-miR-591	CLIP-seq
MIRT2027365	hsa-miR-604	CLIP-seq
MIRT1100493	hsa-miR-614	CLIP-seq
MIRT1100495	hsa-miR-637	CLIP-seq
MIRT1100497	hsa-miR-659	CLIP-seq
MIRT1100498	hsa-miR-708	CLIP-seq
MIRT2027366	hsa-miR-936	CLIP-seq
MIRT2027329	hsa-miR-101	CLIP-seq
MIRT2027330	hsa-miR-1207-5p	CLIP-seq
MIRT2027331	hsa-miR-1237	CLIP-seq
MIRT2027332	hsa-miR-1248	CLIP-seq
MIRT2258615	hsa-miR-1271	CLIP-seq
MIRT1100388	hsa-miR-128	CLIP-seq
MIRT2027333	hsa-miR-1290	CLIP-seq
MIRT1100389	hsa-miR-129-5p	CLIP-seq
MIRT1100390	hsa-miR-1305	CLIP-seq
MIRT1100392	hsa-miR-140-3p	CLIP-seq
MIRT2027335	hsa-miR-144	CLIP-seq
MIRT1100393	hsa-miR-145	CLIP-seq
MIRT1100395	hsa-miR-1470	CLIP-seq
MIRT2258616	hsa-miR-182	CLIP-seq
MIRT1100404	hsa-miR-1825	CLIP-seq
MIRT1100405	hsa-miR-194	CLIP-seq
MIRT1100407	hsa-miR-199a-5p	CLIP-seq
MIRT1100408	hsa-miR-199b-5p	CLIP-seq
MIRT1100409	hsa-miR-203	CLIP-seq
MIRT1100411	hsa-miR-2113	CLIP-seq
MIRT1100412	hsa-miR-2114	CLIP-seq
MIRT1100413	hsa-miR-218	CLIP-seq
MIRT1100414	hsa-miR-27a	CLIP-seq
MIRT1100415	hsa-miR-27b	CLIP-seq
MIRT1100416	hsa-miR-28-5p	CLIP-seq
MIRT1100418	hsa-miR-29a	CLIP-seq
MIRT1100419	hsa-miR-29b	CLIP-seq
MIRT1100420	hsa-miR-29c	CLIP-seq
MIRT1100421	hsa-miR-300	CLIP-seq
MIRT1100422	hsa-miR-3064-3p	CLIP-seq
MIRT1100423	hsa-miR-3065-5p	CLIP-seq
MIRT2027338	hsa-miR-31	CLIP-seq
MIRT2027339	hsa-miR-3128	CLIP-seq
MIRT1100424	hsa-miR-3130-5p	CLIP-seq
MIRT1100425	hsa-miR-3139	CLIP-seq
MIRT1100426	hsa-miR-3148	CLIP-seq
MIRT1100427	hsa-miR-3153	CLIP-seq
MIRT1100428	hsa-miR-3180-5p	CLIP-seq
MIRT1100429	hsa-miR-3192	CLIP-seq
MIRT1100430	hsa-miR-330-3p	CLIP-seq
MIRT2258617	hsa-miR-342-3p	CLIP-seq
MIRT1100432	hsa-miR-361-3p	CLIP-seq
MIRT1100433	hsa-miR-3616-5p	CLIP-seq
MIRT1100434	hsa-miR-3647-5p	CLIP-seq
MIRT2027344	hsa-miR-3688-5p	CLIP-seq
MIRT1100435	hsa-miR-377	CLIP-seq
MIRT1100436	hsa-miR-381	CLIP-seq
MIRT1100437	hsa-miR-3940-5p	CLIP-seq
MIRT1100438	hsa-miR-4256	CLIP-seq
MIRT2258618	hsa-miR-4263	CLIP-seq
MIRT1100440	hsa-miR-4286	CLIP-seq
MIRT1100442	hsa-miR-4302	CLIP-seq
MIRT1100444	hsa-miR-4314	CLIP-seq
MIRT1100446	hsa-miR-4426	CLIP-seq
MIRT1100447	hsa-miR-4433	CLIP-seq
MIRT2027346	hsa-miR-4446-5p	CLIP-seq
MIRT1100449	hsa-miR-4459	CLIP-seq
MIRT2027347	hsa-miR-4467	CLIP-seq
MIRT1100451	hsa-miR-4482	CLIP-seq
MIRT1100452	hsa-miR-4488	CLIP-seq
MIRT1100453	hsa-miR-4494	CLIP-seq
MIRT1100454	hsa-miR-4507	CLIP-seq
MIRT1100456	hsa-miR-4520a-5p	CLIP-seq
MIRT1100457	hsa-miR-4520b-5p	CLIP-seq
MIRT2027349	hsa-miR-4645-5p	CLIP-seq
MIRT1100458	hsa-miR-4646-5p	CLIP-seq
MIRT1100459	hsa-miR-4647	CLIP-seq
MIRT1100460	hsa-miR-4662b	CLIP-seq
MIRT1100461	hsa-miR-4667-3p	CLIP-seq
MIRT1100462	hsa-miR-4667-5p	CLIP-seq
MIRT1100464	hsa-miR-4668-5p	CLIP-seq
MIRT2027350	hsa-miR-4673	CLIP-seq
MIRT1100466	hsa-miR-4697-3p	CLIP-seq
MIRT1100467	hsa-miR-4697-5p	CLIP-seq
MIRT1100468	hsa-miR-4700-5p	CLIP-seq
MIRT1100470	hsa-miR-4713-5p	CLIP-seq
MIRT2027352	hsa-miR-4725-5p	CLIP-seq
MIRT2027353	hsa-miR-4730	CLIP-seq
MIRT2027354	hsa-miR-4736	CLIP-seq
MIRT2027356	hsa-miR-4755-5p	CLIP-seq
MIRT2027357	hsa-miR-4763-3p	CLIP-seq
MIRT1100474	hsa-miR-4768-3p	CLIP-seq
MIRT1100476	hsa-miR-4795-3p	CLIP-seq
MIRT2258619	hsa-miR-4799-5p	CLIP-seq
MIRT1100478	hsa-miR-499a-5p	CLIP-seq
MIRT2027361	hsa-miR-504	CLIP-seq
MIRT1100480	hsa-miR-513a-5p	CLIP-seq
MIRT1100487	hsa-miR-573	CLIP-seq
MIRT2258620	hsa-miR-576-5p	CLIP-seq
MIRT1100488	hsa-miR-584	CLIP-seq
MIRT1100489	hsa-miR-591	CLIP-seq
MIRT1100491	hsa-miR-603	CLIP-seq
MIRT2027365	hsa-miR-604	CLIP-seq
MIRT1100492	hsa-miR-607	CLIP-seq
MIRT1100495	hsa-miR-637	CLIP-seq
MIRT1100496	hsa-miR-656	CLIP-seq
MIRT1100498	hsa-miR-708	CLIP-seq
MIRT2258621	hsa-miR-9	CLIP-seq
MIRT2258622	hsa-miR-96	CLIP-seq
MIRT1100399	hsa-miR-154	CLIP-seq
MIRT1100411	hsa-miR-2113	CLIP-seq
MIRT1100413	hsa-miR-218	CLIP-seq
MIRT1100421	hsa-miR-300	CLIP-seq
MIRT1100422	hsa-miR-3064-3p	CLIP-seq
MIRT1100436	hsa-miR-381	CLIP-seq
MIRT1100440	hsa-miR-4286	CLIP-seq
MIRT1100444	hsa-miR-4314	CLIP-seq
MIRT1100447	hsa-miR-4433	CLIP-seq
MIRT1100449	hsa-miR-4459	CLIP-seq
MIRT1100452	hsa-miR-4488	CLIP-seq
MIRT1100453	hsa-miR-4494	CLIP-seq
MIRT1100458	hsa-miR-4646-5p	CLIP-seq
MIRT1100462	hsa-miR-4667-5p	CLIP-seq
MIRT1100467	hsa-miR-4697-5p	CLIP-seq
MIRT1100468	hsa-miR-4700-5p	CLIP-seq
MIRT1100470	hsa-miR-4713-5p	CLIP-seq
MIRT2390020	hsa-miR-4733-5p	CLIP-seq
MIRT1100473	hsa-miR-4762-3p	CLIP-seq
MIRT1100474	hsa-miR-4768-3p	CLIP-seq
MIRT1100478	hsa-miR-499a-5p	CLIP-seq
MIRT1100495	hsa-miR-637	CLIP-seq
MIRT1100389	hsa-miR-129-5p	CLIP-seq
MIRT1100433	hsa-miR-3616-5p	CLIP-seq
MIRT1100434	hsa-miR-3647-5p	CLIP-seq
MIRT1100437	hsa-miR-3940-5p	CLIP-seq
MIRT1100454	hsa-miR-4507	CLIP-seq
MIRT1100456	hsa-miR-4520a-5p	CLIP-seq
MIRT1100457	hsa-miR-4520b-5p	CLIP-seq
MIRT1100487	hsa-miR-573	CLIP-seq
MIRT1100392	hsa-miR-140-3p	CLIP-seq
MIRT2027336	hsa-miR-199a-3p	CLIP-seq
MIRT2027337	hsa-miR-199b-3p	CLIP-seq
MIRT1100418	hsa-miR-29a	CLIP-seq
MIRT1100419	hsa-miR-29b	CLIP-seq
MIRT1100420	hsa-miR-29c	CLIP-seq
MIRT1100423	hsa-miR-3065-5p	CLIP-seq
MIRT2027340	hsa-miR-3129-5p	CLIP-seq
MIRT2438259	hsa-miR-3155	CLIP-seq
MIRT2438260	hsa-miR-3155b	CLIP-seq
MIRT1100430	hsa-miR-330-3p	CLIP-seq
MIRT1100431	hsa-miR-3607-3p	CLIP-seq
MIRT1100435	hsa-miR-377	CLIP-seq
MIRT2027345	hsa-miR-4279	CLIP-seq
MIRT1100445	hsa-miR-4330	CLIP-seq
MIRT1100453	hsa-miR-4494	CLIP-seq
MIRT1100461	hsa-miR-4667-3p	CLIP-seq
MIRT2438261	hsa-miR-4753-5p	CLIP-seq
MIRT2438262	hsa-miR-4755-3p	CLIP-seq
MIRT2438263	hsa-miR-4786-5p	CLIP-seq
MIRT2027360	hsa-miR-4797-3p	CLIP-seq
MIRT1100478	hsa-miR-499a-5p	CLIP-seq
MIRT2027364	hsa-miR-548p	CLIP-seq
MIRT1100491	hsa-miR-603	CLIP-seq
MIRT2438264	hsa-miR-769-5p	CLIP-seq
MIRT2027366	hsa-miR-936	CLIP-seq
MIRT1100421	hsa-miR-300	CLIP-seq
MIRT1100422	hsa-miR-3064-3p	CLIP-seq
MIRT1100431	hsa-miR-3607-3p	CLIP-seq
MIRT1100435	hsa-miR-377	CLIP-seq
MIRT1100436	hsa-miR-381	CLIP-seq
MIRT1100445	hsa-miR-4330	CLIP-seq
MIRT1100447	hsa-miR-4433	CLIP-seq
MIRT1100449	hsa-miR-4459	CLIP-seq
MIRT1100453	hsa-miR-4494	CLIP-seq
MIRT1100474	hsa-miR-4768-3p	CLIP-seq
MIRT1100478	hsa-miR-499a-5p	CLIP-seq
MIRT1100491	hsa-miR-603	CLIP-seq
MIRT2027329	hsa-miR-101	CLIP-seq
MIRT2027330	hsa-miR-1207-5p	CLIP-seq
MIRT2027331	hsa-miR-1237	CLIP-seq
MIRT2027332	hsa-miR-1248	CLIP-seq
MIRT2559406	hsa-miR-125a-5p	CLIP-seq
MIRT2559407	hsa-miR-125b	CLIP-seq
MIRT2027333	hsa-miR-1290	CLIP-seq
MIRT1100389	hsa-miR-129-5p	CLIP-seq
MIRT1100390	hsa-miR-1305	CLIP-seq
MIRT1100392	hsa-miR-140-3p	CLIP-seq
MIRT2027335	hsa-miR-144	CLIP-seq
MIRT1100395	hsa-miR-1470	CLIP-seq
MIRT2559408	hsa-miR-193a-3p	CLIP-seq
MIRT2559409	hsa-miR-193b	CLIP-seq
MIRT1100405	hsa-miR-194	CLIP-seq
MIRT2027336	hsa-miR-199a-3p	CLIP-seq
MIRT2027337	hsa-miR-199b-3p	CLIP-seq
MIRT1100411	hsa-miR-2113	CLIP-seq
MIRT1100412	hsa-miR-2114	CLIP-seq
MIRT1100413	hsa-miR-218	CLIP-seq
MIRT1100418	hsa-miR-29a	CLIP-seq
MIRT1100419	hsa-miR-29b	CLIP-seq
MIRT1100420	hsa-miR-29c	CLIP-seq
MIRT1100421	hsa-miR-300	CLIP-seq
MIRT1100422	hsa-miR-3064-3p	CLIP-seq
MIRT1100423	hsa-miR-3065-5p	CLIP-seq
MIRT2027338	hsa-miR-31	CLIP-seq
MIRT2027339	hsa-miR-3128	CLIP-seq
MIRT2027340	hsa-miR-3129-5p	CLIP-seq
MIRT1100424	hsa-miR-3130-5p	CLIP-seq
MIRT2438259	hsa-miR-3155	CLIP-seq
MIRT2438260	hsa-miR-3155b	CLIP-seq
MIRT1100430	hsa-miR-330-3p	CLIP-seq
MIRT1100431	hsa-miR-3607-3p	CLIP-seq
MIRT1100432	hsa-miR-361-3p	CLIP-seq
MIRT1100433	hsa-miR-3616-5p	CLIP-seq
MIRT1100434	hsa-miR-3647-5p	CLIP-seq
MIRT2027343	hsa-miR-3650	CLIP-seq
MIRT2559410	hsa-miR-3672	CLIP-seq
MIRT2027344	hsa-miR-3688-5p	CLIP-seq
MIRT1100435	hsa-miR-377	CLIP-seq
MIRT1100436	hsa-miR-381	CLIP-seq
MIRT2559411	hsa-miR-3926	CLIP-seq
MIRT1100437	hsa-miR-3940-5p	CLIP-seq
MIRT2027345	hsa-miR-4279	CLIP-seq
MIRT2559412	hsa-miR-4319	CLIP-seq
MIRT1100445	hsa-miR-4330	CLIP-seq
MIRT2559413	hsa-miR-4417	CLIP-seq
MIRT1100447	hsa-miR-4433	CLIP-seq
MIRT2559414	hsa-miR-4436b-5p	CLIP-seq
MIRT1100449	hsa-miR-4459	CLIP-seq
MIRT2027347	hsa-miR-4467	CLIP-seq
MIRT2027348	hsa-miR-4470	CLIP-seq
MIRT1100451	hsa-miR-4482	CLIP-seq
MIRT1100453	hsa-miR-4494	CLIP-seq
MIRT1100454	hsa-miR-4507	CLIP-seq
MIRT1100456	hsa-miR-4520a-5p	CLIP-seq
MIRT1100457	hsa-miR-4520b-5p	CLIP-seq
MIRT2027349	hsa-miR-4645-5p	CLIP-seq
MIRT1100461	hsa-miR-4667-3p	CLIP-seq
MIRT1100463	hsa-miR-4668-3p	CLIP-seq
MIRT2027350	hsa-miR-4673	CLIP-seq
MIRT2027352	hsa-miR-4725-5p	CLIP-seq
MIRT1100471	hsa-miR-4729	CLIP-seq
MIRT2027353	hsa-miR-4730	CLIP-seq
MIRT2559415	hsa-miR-4732-3p	CLIP-seq
MIRT2027354	hsa-miR-4736	CLIP-seq
MIRT2438261	hsa-miR-4753-5p	CLIP-seq
MIRT2438262	hsa-miR-4755-3p	CLIP-seq
MIRT1100473	hsa-miR-4762-3p	CLIP-seq
MIRT2027357	hsa-miR-4763-3p	CLIP-seq
MIRT1100474	hsa-miR-4768-3p	CLIP-seq
MIRT2438263	hsa-miR-4786-5p	CLIP-seq
MIRT2027360	hsa-miR-4797-3p	CLIP-seq
MIRT2559416	hsa-miR-498	CLIP-seq
MIRT1100478	hsa-miR-499a-5p	CLIP-seq
MIRT2027361	hsa-miR-504	CLIP-seq
MIRT1100479	hsa-miR-513a-3p	CLIP-seq
MIRT2559417	hsa-miR-541	CLIP-seq
MIRT1100483	hsa-miR-548c-3p	CLIP-seq
MIRT2027363	hsa-miR-548m	CLIP-seq
MIRT2027364	hsa-miR-548p	CLIP-seq
MIRT2559418	hsa-miR-548s	CLIP-seq
MIRT1100487	hsa-miR-573	CLIP-seq
MIRT1100491	hsa-miR-603	CLIP-seq
MIRT2027365	hsa-miR-604	CLIP-seq
MIRT2559419	hsa-miR-605	CLIP-seq
MIRT2559420	hsa-miR-654-5p	CLIP-seq
MIRT1100497	hsa-miR-659	CLIP-seq
MIRT2559421	hsa-miR-670	CLIP-seq
MIRT2438264	hsa-miR-769-5p	CLIP-seq
MIRT2027366	hsa-miR-936	CLIP-seq
MIRT2027329	hsa-miR-101	CLIP-seq
MIRT2027330	hsa-miR-1207-5p	CLIP-seq
MIRT2027331	hsa-miR-1237	CLIP-seq
MIRT2027332	hsa-miR-1248	CLIP-seq
MIRT2559406	hsa-miR-125a-5p	CLIP-seq
MIRT2559407	hsa-miR-125b	CLIP-seq
MIRT2027333	hsa-miR-1290	CLIP-seq
MIRT1100389	hsa-miR-129-5p	CLIP-seq
MIRT1100392	hsa-miR-140-3p	CLIP-seq
MIRT2027335	hsa-miR-144	CLIP-seq
MIRT1100395	hsa-miR-1470	CLIP-seq
MIRT2559408	hsa-miR-193a-3p	CLIP-seq
MIRT2559409	hsa-miR-193b	CLIP-seq
MIRT1100405	hsa-miR-194	CLIP-seq
MIRT2027336	hsa-miR-199a-3p	CLIP-seq
MIRT2027337	hsa-miR-199b-3p	CLIP-seq
MIRT1100411	hsa-miR-2113	CLIP-seq
MIRT1100412	hsa-miR-2114	CLIP-seq
MIRT1100413	hsa-miR-218	CLIP-seq
MIRT1100418	hsa-miR-29a	CLIP-seq
MIRT1100419	hsa-miR-29b	CLIP-seq
MIRT1100420	hsa-miR-29c	CLIP-seq
MIRT1100421	hsa-miR-300	CLIP-seq
MIRT1100422	hsa-miR-3064-3p	CLIP-seq
MIRT1100423	hsa-miR-3065-5p	CLIP-seq
MIRT2027338	hsa-miR-31	CLIP-seq
MIRT2027339	hsa-miR-3128	CLIP-seq
MIRT2027340	hsa-miR-3129-5p	CLIP-seq
MIRT1100424	hsa-miR-3130-5p	CLIP-seq
MIRT2438259	hsa-miR-3155	CLIP-seq
MIRT2438260	hsa-miR-3155b	CLIP-seq
MIRT1100430	hsa-miR-330-3p	CLIP-seq
MIRT1100431	hsa-miR-3607-3p	CLIP-seq
MIRT1100432	hsa-miR-361-3p	CLIP-seq
MIRT1100433	hsa-miR-3616-5p	CLIP-seq
MIRT1100434	hsa-miR-3647-5p	CLIP-seq
MIRT2559410	hsa-miR-3672	CLIP-seq
MIRT2683666	hsa-miR-3682-5p	CLIP-seq
MIRT2027344	hsa-miR-3688-5p	CLIP-seq
MIRT1100435	hsa-miR-377	CLIP-seq
MIRT1100436	hsa-miR-381	CLIP-seq
MIRT2559411	hsa-miR-3926	CLIP-seq
MIRT1100437	hsa-miR-3940-5p	CLIP-seq
MIRT2027345	hsa-miR-4279	CLIP-seq
MIRT2559412	hsa-miR-4319	CLIP-seq
MIRT1100445	hsa-miR-4330	CLIP-seq
MIRT2559413	hsa-miR-4417	CLIP-seq
MIRT1100447	hsa-miR-4433	CLIP-seq
MIRT2559414	hsa-miR-4436b-5p	CLIP-seq
MIRT1100449	hsa-miR-4459	CLIP-seq
MIRT2027347	hsa-miR-4467	CLIP-seq
MIRT2027348	hsa-miR-4470	CLIP-seq
MIRT1100451	hsa-miR-4482	CLIP-seq
MIRT1100453	hsa-miR-4494	CLIP-seq
MIRT1100454	hsa-miR-4507	CLIP-seq
MIRT1100456	hsa-miR-4520a-5p	CLIP-seq
MIRT1100457	hsa-miR-4520b-5p	CLIP-seq
MIRT2027349	hsa-miR-4645-5p	CLIP-seq
MIRT1100461	hsa-miR-4667-3p	CLIP-seq
MIRT1100463	hsa-miR-4668-3p	CLIP-seq
MIRT2027350	hsa-miR-4673	CLIP-seq
MIRT2027352	hsa-miR-4725-5p	CLIP-seq
MIRT1100471	hsa-miR-4729	CLIP-seq
MIRT2027353	hsa-miR-4730	CLIP-seq
MIRT2559415	hsa-miR-4732-3p	CLIP-seq
MIRT2027354	hsa-miR-4736	CLIP-seq
MIRT2438261	hsa-miR-4753-5p	CLIP-seq
MIRT2438262	hsa-miR-4755-3p	CLIP-seq
MIRT1100473	hsa-miR-4762-3p	CLIP-seq
MIRT2027357	hsa-miR-4763-3p	CLIP-seq
MIRT1100474	hsa-miR-4768-3p	CLIP-seq
MIRT2438263	hsa-miR-4786-5p	CLIP-seq
MIRT2027360	hsa-miR-4797-3p	CLIP-seq
MIRT1100478	hsa-miR-499a-5p	CLIP-seq
MIRT2027361	hsa-miR-504	CLIP-seq
MIRT1100479	hsa-miR-513a-3p	CLIP-seq
MIRT2559417	hsa-miR-541	CLIP-seq
MIRT1100483	hsa-miR-548c-3p	CLIP-seq
MIRT2027363	hsa-miR-548m	CLIP-seq
MIRT2027364	hsa-miR-548p	CLIP-seq
MIRT2559418	hsa-miR-548s	CLIP-seq
MIRT1100487	hsa-miR-573	CLIP-seq
MIRT1100491	hsa-miR-603	CLIP-seq
MIRT2027365	hsa-miR-604	CLIP-seq
MIRT2559419	hsa-miR-605	CLIP-seq
MIRT2559420	hsa-miR-654-5p	CLIP-seq
MIRT1100497	hsa-miR-659	CLIP-seq
MIRT2559421	hsa-miR-670	CLIP-seq
MIRT2438264	hsa-miR-769-5p	CLIP-seq
MIRT2027366	hsa-miR-936	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
EZH2	Activation	24132643
SRF	Unknown	21131446

Gene ontology (GO) Show/Hide all (67)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005515	Function	Protein binding	IPI	9405152, 10353244, 10523667, 11024021, 11311162, 11971900, 12372823, 15282309, 15494309, 15507604, 15870280, 16314522, 17209048, 17596301, 19668212, 19680228, 20701745, 20818336, 21072240, 21858095, 22084111, 22500989, 24169621, 26195665, 26496610, 28514442, 29734393, 30833792, 3396
GO:0005576	Component	Extracellular region	TAS
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005635	Component	Nuclear envelope	IDA	22701565
GO:0005635	Component	Nuclear envelope	IEA
GO:0005643	Component	Nuclear pore	TAS	7627554
GO:0005654	Component	Nucleoplasm	IDA	9670026
GO:0005654	Component	Nucleoplasm	NAS	7627554, 7892216, 20818336
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	11891849
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005737	Component	Cytoplasm	TAS	7615630
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	NAS	7627554, 7892216, 9670026, 20818336
GO:0005829	Component	Cytosol	TAS
GO:0006404	Process	RNA import into nucleus	IDA	9670026
GO:0006606	Process	Protein import into nucleus	IBA
GO:0006606	Process	Protein import into nucleus	IDA	15964792
GO:0006606	Process	Protein import into nucleus	IDA	7615630, 20818336
GO:0006606	Process	Protein import into nucleus	IEA
GO:0006606	Process	Protein import into nucleus	IEA
GO:0006606	Process	Protein import into nucleus	IMP	17209048
GO:0006606	Process	Protein import into nucleus	ISS
GO:0006607	Process	NLS-bearing protein import into nucleus	IDA	14645851
GO:0006607	Process	NLS-bearing protein import into nucleus	ISS
GO:0006607	Process	NLS-bearing protein import into nucleus	TAS	7627554
GO:0006610	Process	Ribosomal protein import into nucleus	IDA	9687515
GO:0006610	Process	Ribosomal protein import into nucleus	IEA
GO:0006886	Process	Intracellular protein transport	IEA
GO:0007079	Process	Mitotic chromosome movement towards spindle pole	IMP	23783028
GO:0007080	Process	Mitotic metaphase chromosome alignment	IMP	23783028
GO:0008139	Function	Nuclear localization sequence binding	IBA
GO:0008139	Function	Nuclear localization sequence binding	TAS	7627554
GO:0008270	Function	Zinc ion binding	TAS	7615630
GO:0010494	Component	Cytoplasmic stress granule	IEA
GO:0010494	Component	Cytoplasmic stress granule	ISS
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0019899	Function	Enzyme binding	IPI	22701565
GO:0019904	Function	Protein domain specific binding	IPI	11984006
GO:0030953	Process	Astral microtubule organization	IMP	23783028
GO:0031267	Function	Small GTPase binding	IEA
GO:0031965	Component	Nuclear membrane	IDA
GO:0032991	Component	Protein-containing complex	IEA
GO:0035332	Process	Positive regulation of hippo signaling	IDA	38512451
GO:0035580	Component	Specific granule lumen	TAS
GO:0040001	Process	Establishment of mitotic spindle localization	IMP	23783028
GO:0042564	Component	NLS-dependent protein nuclear import complex	IPI	10353244, 10523667, 18187419, 20701745, 20818336
GO:0042564	Component	NLS-dependent protein nuclear import complex	ISS
GO:0045542	Process	Positive regulation of cholesterol biosynthetic process	IDA	12177166
GO:0045542	Process	Positive regulation of cholesterol biosynthetic process	IMP	12177166
GO:0045542	Process	Positive regulation of cholesterol biosynthetic process	ISS
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	21217699
GO:0051879	Function	Hsp90 protein binding	IEA
GO:0061608	Function	Nuclear import signal receptor activity	IBA
GO:0061608	Function	Nuclear import signal receptor activity	IDA	14645851, 20818336
GO:0061608	Function	Nuclear import signal receptor activity	IEA
GO:0061608	Function	Nuclear import signal receptor activity	ISS
GO:0061676	Function	Importin-alpha family protein binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 20458337, 23533145
GO:0071782	Component	Endoplasmic reticulum tubular network	IDA	22701565
GO:0090307	Process	Mitotic spindle assembly	IMP	23783028
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

Other IDs

• MIM: 602738
• HGNC: 6400
• e!Ensembl: ENSG00000108424

Protein

• UniProt ID: Q14974
• Protein name: Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
• Protein function: Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor (Pub
• PDB: 1F59 , 1IBR , 1M5N , 1O6O , 1O6P , 1QGK , 1QGR , 2P8Q , 2Q5D , 2QNA , 3LWW , 3W5K , 6N88 , 6N89 , 8GCN
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00514	Arm	399 → 437	Armadillo/beta-catenin-like repeat	Repeat
  PF03810	IBN_N	21 → 101	Importin-beta N-terminal domain	Family

• Sequence:

  MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ
  IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE
  IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG
  MRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQN
  LVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEA
  AEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCE
  DDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDP
  SVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEA
  AYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSA
  KDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDA
  LQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKN
  YAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDI
  ALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQ
  ENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEAR
  PMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA

• Sequence length: 876

Pathways

KEGG Pathway	Reactome Pathway
Nucleocytoplasmic transport	ISG15 antiviral mechanism
Chemical carcinogenesis - receptor activation	Apoptosis induced DNA fragmentation
	Regulation of cholesterol biosynthesis by SREBP (SREBF)
	Transport of Ribonucleoproteins into the Host Nucleus
	NS1 Mediated Effects on Host Pathways
	Nuclear import of Rev protein
	Initiation of Nuclear Envelope (NE) Reformation
	Neutrophil degranulation
	Inhibition of nitric oxide production

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
ANKYLOSING SPONDYLITIS	—	GWAS catalog	21743469	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, OVARIAN EPITHELIAL	—	CTD	28811376	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE SCLEROSIS	—	GWAS catalog	22190364	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOPATHY	—	GWAS catalog	31220337	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (37)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	29187890		★☆☆☆☆ Found in Text Mining only
Adult Malignant Peripheral Nerve Sheath Tumor	Malignant Peripheral Nerve Sheath Tumor	BEFREE	25890085		★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis, Sporadic	Lateral Sclerosis	BEFREE	30618218		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	29251332	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	35902727	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	38410971	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	28811376	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	35864095	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	28811376		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	CTD_human_DG	28811376		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
cervical cancer	Cervical Cancer	BEFREE	28427184		★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	28427184		★☆☆☆☆ Found in Text Mining only
Childhood Malignant Peripheral Nerve Sheath Tumor	Malignant Peripheral Nerve Sheath Tumor	BEFREE	25890085		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	31629952		★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	28811376		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	29520102, 30742128		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	29520102, 38254206	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	29520102, 30742128		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	27568288		★☆☆☆☆ Found in Text Mining only
Head and Neck Neoplasms	Head and neck neoplasm	Pubtator	26242264	Associate	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	26242264	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	30742095		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28600962, 30742128		★☆☆☆☆ Found in Text Mining only
Malignant Peripheral Nerve Sheath Tumor	Malignant Peripheral Nerve Sheath Tumor	BEFREE	24132643, 25890085		★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	28427184		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	35902727	Stimulate	★☆☆☆☆ Found in Text Mining only
Myeloid Leukemia, Chronic	Myeloid Leukemia	BEFREE	31819526		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	28476803, 31629952		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	37186134	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian Diseases	Ovarian diseases	Pubtator	35295989	Stimulate	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	26242264	Associate	★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	30742095		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	BEFREE	30742095		★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	34069326	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	26242264, 36273446	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	19117056, 30445944	Stimulate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	22125623, 26242264, 28427184, 33530952, 36418423	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

KPNA1 7 shared pathwaysNucleocytoplasmic transport, Chemical carcinogenesis - receptor activation, ISG15 antiviral mechanism, Transport of Ribonucleoproteins into the Host Nucleus, NS1 Mediated Effects on Host Pathways, Apoptosis induced DNA fragmentation, Inhibition of nitric oxide production Related via 7 shared pathways including Nucleocytoplasmic transport, Chemical carcinogenesis - receptor activation. KPNA3 4 shared pathwaysNucleocytoplasmic transport, Chemical carcinogenesis - receptor activation, ISG15 antiviral mechanism, NS1 Mediated Effects on Host Pathways Related via 4 shared pathways including Nucleocytoplasmic transport, Chemical carcinogenesis - receptor activation. KPNA4 4 shared pathwaysNucleocytoplasmic transport, Chemical carcinogenesis - receptor activation, ISG15 antiviral mechanism, NS1 Mediated Effects on Host Pathways Related via 4 shared pathways including Nucleocytoplasmic transport, Chemical carcinogenesis - receptor activation. KPNA5 4 shared pathwaysNucleocytoplasmic transport, Chemical carcinogenesis - receptor activation, ISG15 antiviral mechanism, NS1 Mediated Effects on Host Pathways Related via 4 shared pathways including Nucleocytoplasmic transport, Chemical carcinogenesis - receptor activation. KPNA7 4 shared pathwaysNucleocytoplasmic transport, Chemical carcinogenesis - receptor activation, ISG15 antiviral mechanism, NS1 Mediated Effects on Host Pathways 1 shared evidence sourceGWAS catalog (Ankylosing spondylitis) Related via 4 shared pathways including Nucleocytoplasmic transport, Chemical carcinogenesis - receptor activation — evidence mostly GWAS catalog.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
KPNA1	0	[]	7	["Nucleocytoplasmic transport","Chemical carcinogenesis - receptor activation","ISG15 antiviral mechanism","Transport of Ribonucleoproteins into the Host Nucleus","NS1 Mediated Effects on Host Pathways","Apoptosis induced DNA fragmentation","Inhibition of nitric oxide production"]	0	[]
KPNA3	0	[]	4	["Nucleocytoplasmic transport","Chemical carcinogenesis - receptor activation","ISG15 antiviral mechanism","NS1 Mediated Effects on Host Pathways"]	0	[]
KPNA4	0	[]	4	["Nucleocytoplasmic transport","Chemical carcinogenesis - receptor activation","ISG15 antiviral mechanism","NS1 Mediated Effects on Host Pathways"]	0	[]
KPNA5	0	[]	4	["Nucleocytoplasmic transport","Chemical carcinogenesis - receptor activation","ISG15 antiviral mechanism","NS1 Mediated Effects on Host Pathways"]	0	[]
KPNA7	0	[]	4	["Nucleocytoplasmic transport","Chemical carcinogenesis - receptor activation","ISG15 antiviral mechanism","NS1 Mediated Effects on Host Pathways"]	1	["GWAS catalog (Ankylosing spondylitis)"]

Diseases Linked via Similar Genes

Parkinson disease Linked via 2 of 5 related genesKPNA1, KPNA3 Schizophrenia Linked via 2 of 5 related genesKPNA1, KPNA3 Psoriasis Linked via 2 of 5 related genesKPNA3, KPNA7 Eczema Linked via 1 of 5 related genesKPNA3 Spastic paraplegia Linked via 1 of 5 related genesKPNA3

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Parkinson disease	2	["KPNA1","KPNA3"]
Schizophrenia	2	["KPNA1","KPNA3"]
Psoriasis	2	["KPNA3","KPNA7"]
Eczema	1	["KPNA3"]
Spastic paraplegia	1	["KPNA3"]