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Gene Gene information from NCBI Gene database.
Entrez ID 92856
Gene name IMP U3 small nucleolar ribonucleoprotein 4
Gene symbol IMP4
Synonyms (NCBI Gene)
BXDC4
Chromosome 2
Chromosome location 2q21.1
Summary The protein encoded by this gene, along with IMP3 and MPP10, is part of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) complex. This complex is necessary for the early cleavage steps of pre-18S ribosomal RNA processing. Several transcript var
miRNA miRNA information provided by mirtarbase database.
264 Show/Hide all (264)
miRTarBase ID miRNA Experiments Reference
MIRT027762 hsa-miR-98-5p Microarray 19088304
MIRT044455 hsa-miR-320a CLASH 23622248
MIRT716711 hsa-miR-7160-3p HITS-CLIP 19536157
MIRT716712 hsa-miR-6752-3p HITS-CLIP 19536157
MIRT643893 hsa-miR-6747-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
28 Show/Hide all (28)
GO ID Ontology Definition Evidence Reference
GO:0001650 Component Fibrillar center IDA
GO:0005515 Function Protein binding IPI 12655004, 21516116, 25416956, 32296183, 35271311
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IEA
GO:0005654 Component Nucleoplasm TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612981 30856 ENSG00000136718
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96G21
Protein name U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4) (Brix domain-containing protein 4)
Protein function Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukary
PDB 7MQ8 , 7MQ9 , 7MQA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04427 Brix 90 → 257 Brix domain Domain
Sequence
MLRREARLRREYLYRKAREEAQRSAQERKERLRRALEENRLIPTELRREALALQGSLEFD
DAGGEGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHE
VGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMS
EAKPHLITHGFSSRLGKRVSDILRYLFPVPKDDSHRVITFANQDDYISFRHHVYKKTDHR
NVELTEVGPRFELKLYM
IRLGTLEQEATADVEWRWHPYTNTARKRVFLSTE
Sequence length 291
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Ribosome biogenesis in eukaryotes Major pathway of rRNA processing in the nucleolus and cytosol