EXOSC6 (exosome component 6)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 118460
• Gene name: Exosome component 6
• Gene symbol: EXOSC6
• Synonyms (NCBI Gene): EAP4, MTR3, Mtr3p, hMtr3p, p11
• Chromosome: 16
• Chromosome location: 16q22.1
• Summary: This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its

miRNA Show/Hide all (562)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049776	hsa-miR-92a-3p	CLASH	23622248
MIRT683712	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT709010	hsa-miR-3163	HITS-CLIP	19536157
MIRT709009	hsa-miR-340-3p	HITS-CLIP	19536157
MIRT709008	hsa-miR-6827-3p	HITS-CLIP	19536157
MIRT709007	hsa-miR-4738-3p	HITS-CLIP	19536157
MIRT683707	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT683712	hsa-miR-548c-3p	HITS-CLIP	23313552
MIRT683711	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT683710	hsa-miR-942-3p	HITS-CLIP	23313552
MIRT683709	hsa-miR-3675-3p	HITS-CLIP	23313552
MIRT683708	hsa-miR-4717-3p	HITS-CLIP	23313552
MIRT683707	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT661892	hsa-miR-374c-3p	HITS-CLIP	23824327
MIRT661891	hsa-miR-4779	HITS-CLIP	23824327
MIRT661890	hsa-miR-3929	HITS-CLIP	23824327
MIRT661889	hsa-miR-4419b	HITS-CLIP	23824327
MIRT661888	hsa-miR-4478	HITS-CLIP	23824327
MIRT661887	hsa-miR-5690	HITS-CLIP	23824327
MIRT661886	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT661885	hsa-miR-665	HITS-CLIP	23824327
MIRT661884	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT661883	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT661882	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT661881	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT661880	hsa-miR-4266	HITS-CLIP	23824327
MIRT643538	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT643537	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT643536	hsa-miR-889-3p	HITS-CLIP	23824327
MIRT543624	hsa-miR-5692a	PAR-CLIP	21572407
MIRT683712	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT709010	hsa-miR-3163	HITS-CLIP	19536157
MIRT709009	hsa-miR-340-3p	HITS-CLIP	19536157
MIRT709008	hsa-miR-6827-3p	HITS-CLIP	19536157
MIRT709007	hsa-miR-4738-3p	HITS-CLIP	19536157
MIRT683707	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT683712	hsa-miR-548c-3p	HITS-CLIP	23313552
MIRT683711	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT683710	hsa-miR-942-3p	HITS-CLIP	23313552
MIRT683709	hsa-miR-3675-3p	HITS-CLIP	23313552
MIRT683708	hsa-miR-4717-3p	HITS-CLIP	23313552
MIRT683707	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT661892	hsa-miR-374c-3p	HITS-CLIP	23824327
MIRT661891	hsa-miR-4779	HITS-CLIP	23824327
MIRT661890	hsa-miR-3929	HITS-CLIP	23824327
MIRT661889	hsa-miR-4419b	HITS-CLIP	23824327
MIRT661888	hsa-miR-4478	HITS-CLIP	23824327
MIRT661887	hsa-miR-5690	HITS-CLIP	23824327
MIRT661886	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT661885	hsa-miR-665	HITS-CLIP	23824327
MIRT661884	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT661883	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT661882	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT661881	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT661880	hsa-miR-4266	HITS-CLIP	23824327
MIRT643538	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT643537	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT643536	hsa-miR-889-3p	HITS-CLIP	23824327
MIRT543624	hsa-miR-5692a	PAR-CLIP	21572407
MIRT973232	hsa-miR-1200	CLIP-seq
MIRT973233	hsa-miR-1207-3p	CLIP-seq
MIRT973234	hsa-miR-1224-3p	CLIP-seq
MIRT973235	hsa-miR-1228	CLIP-seq
MIRT973236	hsa-miR-1260	CLIP-seq
MIRT973237	hsa-miR-1260b	CLIP-seq
MIRT973238	hsa-miR-1267	CLIP-seq
MIRT973239	hsa-miR-1273g	CLIP-seq
MIRT973240	hsa-miR-128	CLIP-seq
MIRT973241	hsa-miR-1280	CLIP-seq
MIRT973242	hsa-miR-1285	CLIP-seq
MIRT973243	hsa-miR-140-3p	CLIP-seq
MIRT973244	hsa-miR-181a	CLIP-seq
MIRT973245	hsa-miR-181b	CLIP-seq
MIRT973246	hsa-miR-181c	CLIP-seq
MIRT973247	hsa-miR-181d	CLIP-seq
MIRT973248	hsa-miR-1827	CLIP-seq
MIRT973249	hsa-miR-184	CLIP-seq
MIRT973250	hsa-miR-1910	CLIP-seq
MIRT973251	hsa-miR-193a-5p	CLIP-seq
MIRT973252	hsa-miR-19a	CLIP-seq
MIRT973253	hsa-miR-19b	CLIP-seq
MIRT973254	hsa-miR-200b	CLIP-seq
MIRT973255	hsa-miR-200c	CLIP-seq
MIRT973256	hsa-miR-2114	CLIP-seq
MIRT973257	hsa-miR-221	CLIP-seq
MIRT973258	hsa-miR-222	CLIP-seq
MIRT973259	hsa-miR-2277-5p	CLIP-seq
MIRT973260	hsa-miR-24	CLIP-seq
MIRT973261	hsa-miR-2467-3p	CLIP-seq
MIRT973262	hsa-miR-25	CLIP-seq
MIRT973263	hsa-miR-2964a-5p	CLIP-seq
MIRT973264	hsa-miR-3074-3p	CLIP-seq
MIRT973265	hsa-miR-3120-3p	CLIP-seq
MIRT973266	hsa-miR-3122	CLIP-seq
MIRT973267	hsa-miR-3126-3p	CLIP-seq
MIRT973268	hsa-miR-3127-5p	CLIP-seq
MIRT973269	hsa-miR-3128	CLIP-seq
MIRT973270	hsa-miR-3136-3p	CLIP-seq
MIRT973271	hsa-miR-3140-5p	CLIP-seq
MIRT973272	hsa-miR-3165	CLIP-seq
MIRT973273	hsa-miR-3187-5p	CLIP-seq
MIRT973274	hsa-miR-32	CLIP-seq
MIRT973275	hsa-miR-338-3p	CLIP-seq
MIRT973276	hsa-miR-342-3p	CLIP-seq
MIRT973277	hsa-miR-34a	CLIP-seq
MIRT973278	hsa-miR-34c-5p	CLIP-seq
MIRT973279	hsa-miR-3612	CLIP-seq
MIRT973280	hsa-miR-3621	CLIP-seq
MIRT973281	hsa-miR-3622a-3p	CLIP-seq
MIRT973282	hsa-miR-3622b-3p	CLIP-seq
MIRT973283	hsa-miR-363	CLIP-seq
MIRT973284	hsa-miR-3647-3p	CLIP-seq
MIRT973285	hsa-miR-3656	CLIP-seq
MIRT973286	hsa-miR-367	CLIP-seq
MIRT973287	hsa-miR-3677-3p	CLIP-seq
MIRT973288	hsa-miR-3678-5p	CLIP-seq
MIRT973289	hsa-miR-3689a-3p	CLIP-seq
MIRT973290	hsa-miR-3689c	CLIP-seq
MIRT973291	hsa-miR-3691-3p	CLIP-seq
MIRT973292	hsa-miR-369-3p	CLIP-seq
MIRT973293	hsa-miR-3714	CLIP-seq
MIRT973294	hsa-miR-3913-5p	CLIP-seq
MIRT973295	hsa-miR-3918	CLIP-seq
MIRT973296	hsa-miR-3934	CLIP-seq
MIRT973297	hsa-miR-4257	CLIP-seq
MIRT973298	hsa-miR-4262	CLIP-seq
MIRT973299	hsa-miR-4267	CLIP-seq
MIRT973300	hsa-miR-4269	CLIP-seq
MIRT973301	hsa-miR-4284	CLIP-seq
MIRT973302	hsa-miR-429	CLIP-seq
MIRT973303	hsa-miR-4310	CLIP-seq
MIRT973304	hsa-miR-4325	CLIP-seq
MIRT973305	hsa-miR-4432	CLIP-seq
MIRT973306	hsa-miR-4459	CLIP-seq
MIRT973307	hsa-miR-449a	CLIP-seq
MIRT973308	hsa-miR-449b	CLIP-seq
MIRT973309	hsa-miR-4514	CLIP-seq
MIRT973310	hsa-miR-4530	CLIP-seq
MIRT973311	hsa-miR-455-3p	CLIP-seq
MIRT973312	hsa-miR-4634	CLIP-seq
MIRT973313	hsa-miR-4638-5p	CLIP-seq
MIRT973314	hsa-miR-4660	CLIP-seq
MIRT973315	hsa-miR-4662a-5p	CLIP-seq
MIRT973316	hsa-miR-4675	CLIP-seq
MIRT973317	hsa-miR-4676-5p	CLIP-seq
MIRT973318	hsa-miR-4685-5p	CLIP-seq
MIRT973319	hsa-miR-4687-3p	CLIP-seq
MIRT973320	hsa-miR-4692	CLIP-seq
MIRT973321	hsa-miR-4695-5p	CLIP-seq
MIRT973322	hsa-miR-4699-3p	CLIP-seq
MIRT973323	hsa-miR-4703-3p	CLIP-seq
MIRT973324	hsa-miR-4720-5p	CLIP-seq
MIRT973325	hsa-miR-4725-5p	CLIP-seq
MIRT973326	hsa-miR-4728-5p	CLIP-seq
MIRT973327	hsa-miR-4741	CLIP-seq
MIRT973328	hsa-miR-4742-5p	CLIP-seq
MIRT973329	hsa-miR-4773	CLIP-seq
MIRT973330	hsa-miR-4778-5p	CLIP-seq
MIRT973331	hsa-miR-4789-3p	CLIP-seq
MIRT973332	hsa-miR-4799-3p	CLIP-seq
MIRT973333	hsa-miR-4804-5p	CLIP-seq
MIRT973334	hsa-miR-501-3p	CLIP-seq
MIRT973335	hsa-miR-502-3p	CLIP-seq
MIRT973336	hsa-miR-504	CLIP-seq
MIRT973337	hsa-miR-508-5p	CLIP-seq
MIRT973338	hsa-miR-510	CLIP-seq
MIRT973339	hsa-miR-512-5p	CLIP-seq
MIRT973340	hsa-miR-544b	CLIP-seq
MIRT973341	hsa-miR-548v	CLIP-seq
MIRT973342	hsa-miR-551a	CLIP-seq
MIRT973343	hsa-miR-551b	CLIP-seq
MIRT973344	hsa-miR-570	CLIP-seq
MIRT973345	hsa-miR-575	CLIP-seq
MIRT973346	hsa-miR-612	CLIP-seq
MIRT973347	hsa-miR-650	CLIP-seq
MIRT973348	hsa-miR-652	CLIP-seq
MIRT973349	hsa-miR-661	CLIP-seq
MIRT973350	hsa-miR-766	CLIP-seq
MIRT973351	hsa-miR-767-5p	CLIP-seq
MIRT973352	hsa-miR-888	CLIP-seq
MIRT973353	hsa-miR-92a	CLIP-seq
MIRT973354	hsa-miR-92b	CLIP-seq
MIRT973232	hsa-miR-1200	CLIP-seq
MIRT973233	hsa-miR-1207-3p	CLIP-seq
MIRT973235	hsa-miR-1228	CLIP-seq
MIRT1988368	hsa-miR-1246	CLIP-seq
MIRT973239	hsa-miR-1273g	CLIP-seq
MIRT973240	hsa-miR-128	CLIP-seq
MIRT973242	hsa-miR-1285	CLIP-seq
MIRT973243	hsa-miR-140-3p	CLIP-seq
MIRT973244	hsa-miR-181a	CLIP-seq
MIRT973245	hsa-miR-181b	CLIP-seq
MIRT973246	hsa-miR-181c	CLIP-seq
MIRT973247	hsa-miR-181d	CLIP-seq
MIRT973248	hsa-miR-1827	CLIP-seq
MIRT973250	hsa-miR-1910	CLIP-seq
MIRT973252	hsa-miR-19a	CLIP-seq
MIRT973253	hsa-miR-19b	CLIP-seq
MIRT973254	hsa-miR-200b	CLIP-seq
MIRT973255	hsa-miR-200c	CLIP-seq
MIRT973256	hsa-miR-2114	CLIP-seq
MIRT973257	hsa-miR-221	CLIP-seq
MIRT973258	hsa-miR-222	CLIP-seq
MIRT973260	hsa-miR-24	CLIP-seq
MIRT973263	hsa-miR-2964a-5p	CLIP-seq
MIRT973264	hsa-miR-3074-3p	CLIP-seq
MIRT973265	hsa-miR-3120-3p	CLIP-seq
MIRT973266	hsa-miR-3122	CLIP-seq
MIRT973267	hsa-miR-3126-3p	CLIP-seq
MIRT973268	hsa-miR-3127-5p	CLIP-seq
MIRT973269	hsa-miR-3128	CLIP-seq
MIRT973270	hsa-miR-3136-3p	CLIP-seq
MIRT1988369	hsa-miR-3152-5p	CLIP-seq
MIRT973272	hsa-miR-3165	CLIP-seq
MIRT973273	hsa-miR-3187-5p	CLIP-seq
MIRT973275	hsa-miR-338-3p	CLIP-seq
MIRT973276	hsa-miR-342-3p	CLIP-seq
MIRT973277	hsa-miR-34a	CLIP-seq
MIRT973278	hsa-miR-34c-5p	CLIP-seq
MIRT973279	hsa-miR-3612	CLIP-seq
MIRT973281	hsa-miR-3622a-3p	CLIP-seq
MIRT973282	hsa-miR-3622b-3p	CLIP-seq
MIRT973285	hsa-miR-3656	CLIP-seq
MIRT973288	hsa-miR-3678-5p	CLIP-seq
MIRT973289	hsa-miR-3689a-3p	CLIP-seq
MIRT973290	hsa-miR-3689c	CLIP-seq
MIRT973291	hsa-miR-3691-3p	CLIP-seq
MIRT973292	hsa-miR-369-3p	CLIP-seq
MIRT973293	hsa-miR-3714	CLIP-seq
MIRT973294	hsa-miR-3913-5p	CLIP-seq
MIRT973295	hsa-miR-3918	CLIP-seq
MIRT973298	hsa-miR-4262	CLIP-seq
MIRT973299	hsa-miR-4267	CLIP-seq
MIRT973300	hsa-miR-4269	CLIP-seq
MIRT973301	hsa-miR-4284	CLIP-seq
MIRT973302	hsa-miR-429	CLIP-seq
MIRT973303	hsa-miR-4310	CLIP-seq
MIRT1988370	hsa-miR-4443	CLIP-seq
MIRT973306	hsa-miR-4459	CLIP-seq
MIRT973307	hsa-miR-449a	CLIP-seq
MIRT973308	hsa-miR-449b	CLIP-seq
MIRT973309	hsa-miR-4514	CLIP-seq
MIRT973310	hsa-miR-4530	CLIP-seq
MIRT973311	hsa-miR-455-3p	CLIP-seq
MIRT973314	hsa-miR-4660	CLIP-seq
MIRT973315	hsa-miR-4662a-5p	CLIP-seq
MIRT973318	hsa-miR-4685-5p	CLIP-seq
MIRT973320	hsa-miR-4692	CLIP-seq
MIRT973322	hsa-miR-4699-3p	CLIP-seq
MIRT1988371	hsa-miR-4705	CLIP-seq
MIRT973324	hsa-miR-4720-5p	CLIP-seq
MIRT1988372	hsa-miR-4722-5p	CLIP-seq
MIRT973326	hsa-miR-4728-5p	CLIP-seq
MIRT973328	hsa-miR-4742-5p	CLIP-seq
MIRT973329	hsa-miR-4773	CLIP-seq
MIRT1988373	hsa-miR-4774-3p	CLIP-seq
MIRT973330	hsa-miR-4778-5p	CLIP-seq
MIRT973331	hsa-miR-4789-3p	CLIP-seq
MIRT973332	hsa-miR-4799-3p	CLIP-seq
MIRT973334	hsa-miR-501-3p	CLIP-seq
MIRT973335	hsa-miR-502-3p	CLIP-seq
MIRT973338	hsa-miR-510	CLIP-seq
MIRT973339	hsa-miR-512-5p	CLIP-seq
MIRT1988374	hsa-miR-516a-5p	CLIP-seq
MIRT973340	hsa-miR-544b	CLIP-seq
MIRT973341	hsa-miR-548v	CLIP-seq
MIRT973344	hsa-miR-570	CLIP-seq
MIRT973346	hsa-miR-612	CLIP-seq
MIRT973347	hsa-miR-650	CLIP-seq
MIRT973348	hsa-miR-652	CLIP-seq
MIRT1988375	hsa-miR-890	CLIP-seq
MIRT1988376	hsa-miR-940	CLIP-seq
MIRT973232	hsa-miR-1200	CLIP-seq
MIRT973233	hsa-miR-1207-3p	CLIP-seq
MIRT973235	hsa-miR-1228	CLIP-seq
MIRT973238	hsa-miR-1267	CLIP-seq
MIRT973240	hsa-miR-128	CLIP-seq
MIRT973242	hsa-miR-1285	CLIP-seq
MIRT973244	hsa-miR-181a	CLIP-seq
MIRT973245	hsa-miR-181b	CLIP-seq
MIRT973246	hsa-miR-181c	CLIP-seq
MIRT973247	hsa-miR-181d	CLIP-seq
MIRT973248	hsa-miR-1827	CLIP-seq
MIRT973249	hsa-miR-184	CLIP-seq
MIRT973251	hsa-miR-193a-5p	CLIP-seq
MIRT973252	hsa-miR-19a	CLIP-seq
MIRT973253	hsa-miR-19b	CLIP-seq
MIRT973254	hsa-miR-200b	CLIP-seq
MIRT973255	hsa-miR-200c	CLIP-seq
MIRT973256	hsa-miR-2114	CLIP-seq
MIRT973257	hsa-miR-221	CLIP-seq
MIRT973258	hsa-miR-222	CLIP-seq
MIRT973259	hsa-miR-2277-5p	CLIP-seq
MIRT973260	hsa-miR-24	CLIP-seq
MIRT973261	hsa-miR-2467-3p	CLIP-seq
MIRT973262	hsa-miR-25	CLIP-seq
MIRT973263	hsa-miR-2964a-5p	CLIP-seq
MIRT973264	hsa-miR-3074-3p	CLIP-seq
MIRT973265	hsa-miR-3120-3p	CLIP-seq
MIRT973266	hsa-miR-3122	CLIP-seq
MIRT973268	hsa-miR-3127-5p	CLIP-seq
MIRT973270	hsa-miR-3136-3p	CLIP-seq
MIRT973271	hsa-miR-3140-5p	CLIP-seq
MIRT1988369	hsa-miR-3152-5p	CLIP-seq
MIRT973272	hsa-miR-3165	CLIP-seq
MIRT973273	hsa-miR-3187-5p	CLIP-seq
MIRT973274	hsa-miR-32	CLIP-seq
MIRT973275	hsa-miR-338-3p	CLIP-seq
MIRT973276	hsa-miR-342-3p	CLIP-seq
MIRT973279	hsa-miR-3612	CLIP-seq
MIRT973280	hsa-miR-3621	CLIP-seq
MIRT973281	hsa-miR-3622a-3p	CLIP-seq
MIRT973282	hsa-miR-3622b-3p	CLIP-seq
MIRT973283	hsa-miR-363	CLIP-seq
MIRT973285	hsa-miR-3656	CLIP-seq
MIRT973286	hsa-miR-367	CLIP-seq
MIRT973287	hsa-miR-3677-3p	CLIP-seq
MIRT973288	hsa-miR-3678-5p	CLIP-seq
MIRT973289	hsa-miR-3689a-3p	CLIP-seq
MIRT973290	hsa-miR-3689c	CLIP-seq
MIRT973291	hsa-miR-3691-3p	CLIP-seq
MIRT973292	hsa-miR-369-3p	CLIP-seq
MIRT973293	hsa-miR-3714	CLIP-seq
MIRT973294	hsa-miR-3913-5p	CLIP-seq
MIRT973295	hsa-miR-3918	CLIP-seq
MIRT2222825	hsa-miR-3940-3p	CLIP-seq
MIRT973297	hsa-miR-4257	CLIP-seq
MIRT973298	hsa-miR-4262	CLIP-seq
MIRT973299	hsa-miR-4267	CLIP-seq
MIRT973300	hsa-miR-4269	CLIP-seq
MIRT973301	hsa-miR-4284	CLIP-seq
MIRT973302	hsa-miR-429	CLIP-seq
MIRT973303	hsa-miR-4310	CLIP-seq
MIRT973304	hsa-miR-4325	CLIP-seq
MIRT1988370	hsa-miR-4443	CLIP-seq
MIRT973306	hsa-miR-4459	CLIP-seq
MIRT973309	hsa-miR-4514	CLIP-seq
MIRT973310	hsa-miR-4530	CLIP-seq
MIRT2222826	hsa-miR-455-5p	CLIP-seq
MIRT973312	hsa-miR-4634	CLIP-seq
MIRT973313	hsa-miR-4638-5p	CLIP-seq
MIRT973314	hsa-miR-4660	CLIP-seq
MIRT973316	hsa-miR-4675	CLIP-seq
MIRT973318	hsa-miR-4685-5p	CLIP-seq
MIRT973319	hsa-miR-4687-3p	CLIP-seq
MIRT973320	hsa-miR-4692	CLIP-seq
MIRT973321	hsa-miR-4695-5p	CLIP-seq
MIRT973322	hsa-miR-4699-3p	CLIP-seq
MIRT973323	hsa-miR-4703-3p	CLIP-seq
MIRT1988371	hsa-miR-4705	CLIP-seq
MIRT1988372	hsa-miR-4722-5p	CLIP-seq
MIRT973325	hsa-miR-4725-5p	CLIP-seq
MIRT973326	hsa-miR-4728-5p	CLIP-seq
MIRT973327	hsa-miR-4741	CLIP-seq
MIRT973328	hsa-miR-4742-5p	CLIP-seq
MIRT973329	hsa-miR-4773	CLIP-seq
MIRT1988373	hsa-miR-4774-3p	CLIP-seq
MIRT973330	hsa-miR-4778-5p	CLIP-seq
MIRT973331	hsa-miR-4789-3p	CLIP-seq
MIRT2222827	hsa-miR-4802-5p	CLIP-seq
MIRT973333	hsa-miR-4804-5p	CLIP-seq
MIRT973334	hsa-miR-501-3p	CLIP-seq
MIRT973335	hsa-miR-502-3p	CLIP-seq
MIRT973336	hsa-miR-504	CLIP-seq
MIRT973337	hsa-miR-508-5p	CLIP-seq
MIRT973338	hsa-miR-510	CLIP-seq
MIRT973339	hsa-miR-512-5p	CLIP-seq
MIRT1988374	hsa-miR-516a-5p	CLIP-seq
MIRT973340	hsa-miR-544b	CLIP-seq
MIRT973341	hsa-miR-548v	CLIP-seq
MIRT2222828	hsa-miR-550a	CLIP-seq
MIRT973342	hsa-miR-551a	CLIP-seq
MIRT973343	hsa-miR-551b	CLIP-seq
MIRT973346	hsa-miR-612	CLIP-seq
MIRT973347	hsa-miR-650	CLIP-seq
MIRT973348	hsa-miR-652	CLIP-seq
MIRT973349	hsa-miR-661	CLIP-seq
MIRT973350	hsa-miR-766	CLIP-seq
MIRT973351	hsa-miR-767-5p	CLIP-seq
MIRT973353	hsa-miR-92a	CLIP-seq
MIRT973354	hsa-miR-92b	CLIP-seq
MIRT1988376	hsa-miR-940	CLIP-seq
MIRT973235	hsa-miR-1228	CLIP-seq
MIRT973260	hsa-miR-24	CLIP-seq
MIRT973266	hsa-miR-3122	CLIP-seq
MIRT973272	hsa-miR-3165	CLIP-seq
MIRT973275	hsa-miR-338-3p	CLIP-seq
MIRT973276	hsa-miR-342-3p	CLIP-seq
MIRT973281	hsa-miR-3622a-3p	CLIP-seq
MIRT973282	hsa-miR-3622b-3p	CLIP-seq
MIRT973285	hsa-miR-3656	CLIP-seq
MIRT973289	hsa-miR-3689a-3p	CLIP-seq
MIRT973290	hsa-miR-3689c	CLIP-seq
MIRT973294	hsa-miR-3913-5p	CLIP-seq
MIRT973300	hsa-miR-4269	CLIP-seq
MIRT973301	hsa-miR-4284	CLIP-seq
MIRT973304	hsa-miR-4325	CLIP-seq
MIRT973309	hsa-miR-4514	CLIP-seq
MIRT973310	hsa-miR-4530	CLIP-seq
MIRT973320	hsa-miR-4692	CLIP-seq
MIRT973326	hsa-miR-4728-5p	CLIP-seq
MIRT973328	hsa-miR-4742-5p	CLIP-seq
MIRT973337	hsa-miR-508-5p	CLIP-seq
MIRT973340	hsa-miR-544b	CLIP-seq
MIRT973235	hsa-miR-1228	CLIP-seq
MIRT973242	hsa-miR-1285	CLIP-seq
MIRT973256	hsa-miR-2114	CLIP-seq
MIRT973262	hsa-miR-25	CLIP-seq
MIRT973266	hsa-miR-3122	CLIP-seq
MIRT973273	hsa-miR-3187-5p	CLIP-seq
MIRT973274	hsa-miR-32	CLIP-seq
MIRT973275	hsa-miR-338-3p	CLIP-seq
MIRT973283	hsa-miR-363	CLIP-seq
MIRT973285	hsa-miR-3656	CLIP-seq
MIRT973286	hsa-miR-367	CLIP-seq
MIRT973289	hsa-miR-3689a-3p	CLIP-seq
MIRT973290	hsa-miR-3689c	CLIP-seq
MIRT973293	hsa-miR-3714	CLIP-seq
MIRT973294	hsa-miR-3913-5p	CLIP-seq
MIRT973304	hsa-miR-4325	CLIP-seq
MIRT973305	hsa-miR-4432	CLIP-seq
MIRT973306	hsa-miR-4459	CLIP-seq
MIRT973310	hsa-miR-4530	CLIP-seq
MIRT1988372	hsa-miR-4722-5p	CLIP-seq
MIRT973326	hsa-miR-4728-5p	CLIP-seq
MIRT973334	hsa-miR-501-3p	CLIP-seq
MIRT973335	hsa-miR-502-3p	CLIP-seq
MIRT973337	hsa-miR-508-5p	CLIP-seq
MIRT973346	hsa-miR-612	CLIP-seq
MIRT973349	hsa-miR-661	CLIP-seq
MIRT973350	hsa-miR-766	CLIP-seq
MIRT973353	hsa-miR-92a	CLIP-seq
MIRT973354	hsa-miR-92b	CLIP-seq
MIRT1988376	hsa-miR-940	CLIP-seq
MIRT973256	hsa-miR-2114	CLIP-seq
MIRT973266	hsa-miR-3122	CLIP-seq
MIRT973289	hsa-miR-3689a-3p	CLIP-seq
MIRT973290	hsa-miR-3689c	CLIP-seq
MIRT973293	hsa-miR-3714	CLIP-seq
MIRT973294	hsa-miR-3913-5p	CLIP-seq
MIRT1988372	hsa-miR-4722-5p	CLIP-seq
MIRT973326	hsa-miR-4728-5p	CLIP-seq
MIRT973334	hsa-miR-501-3p	CLIP-seq
MIRT973335	hsa-miR-502-3p	CLIP-seq
MIRT1988376	hsa-miR-940	CLIP-seq
MIRT973232	hsa-miR-1200	CLIP-seq
MIRT973235	hsa-miR-1228	CLIP-seq
MIRT973242	hsa-miR-1285	CLIP-seq
MIRT973244	hsa-miR-181a	CLIP-seq
MIRT973245	hsa-miR-181b	CLIP-seq
MIRT973246	hsa-miR-181c	CLIP-seq
MIRT973247	hsa-miR-181d	CLIP-seq
MIRT973254	hsa-miR-200b	CLIP-seq
MIRT973255	hsa-miR-200c	CLIP-seq
MIRT973256	hsa-miR-2114	CLIP-seq
MIRT973257	hsa-miR-221	CLIP-seq
MIRT973258	hsa-miR-222	CLIP-seq
MIRT973262	hsa-miR-25	CLIP-seq
MIRT973263	hsa-miR-2964a-5p	CLIP-seq
MIRT973265	hsa-miR-3120-3p	CLIP-seq
MIRT973266	hsa-miR-3122	CLIP-seq
MIRT973270	hsa-miR-3136-3p	CLIP-seq
MIRT973272	hsa-miR-3165	CLIP-seq
MIRT973273	hsa-miR-3187-5p	CLIP-seq
MIRT973274	hsa-miR-32	CLIP-seq
MIRT973275	hsa-miR-338-3p	CLIP-seq
MIRT973279	hsa-miR-3612	CLIP-seq
MIRT973281	hsa-miR-3622a-3p	CLIP-seq
MIRT973282	hsa-miR-3622b-3p	CLIP-seq
MIRT973283	hsa-miR-363	CLIP-seq
MIRT973285	hsa-miR-3656	CLIP-seq
MIRT973286	hsa-miR-367	CLIP-seq
MIRT973288	hsa-miR-3678-5p	CLIP-seq
MIRT973289	hsa-miR-3689a-3p	CLIP-seq
MIRT973290	hsa-miR-3689c	CLIP-seq
MIRT973292	hsa-miR-369-3p	CLIP-seq
MIRT973293	hsa-miR-3714	CLIP-seq
MIRT973294	hsa-miR-3913-5p	CLIP-seq
MIRT973295	hsa-miR-3918	CLIP-seq
MIRT2222825	hsa-miR-3940-3p	CLIP-seq
MIRT973298	hsa-miR-4262	CLIP-seq
MIRT973300	hsa-miR-4269	CLIP-seq
MIRT973302	hsa-miR-429	CLIP-seq
MIRT973303	hsa-miR-4310	CLIP-seq
MIRT973304	hsa-miR-4325	CLIP-seq
MIRT973305	hsa-miR-4432	CLIP-seq
MIRT1988370	hsa-miR-4443	CLIP-seq
MIRT973306	hsa-miR-4459	CLIP-seq
MIRT973309	hsa-miR-4514	CLIP-seq
MIRT973310	hsa-miR-4530	CLIP-seq
MIRT2222826	hsa-miR-455-5p	CLIP-seq
MIRT973318	hsa-miR-4685-5p	CLIP-seq
MIRT973320	hsa-miR-4692	CLIP-seq
MIRT1988372	hsa-miR-4722-5p	CLIP-seq
MIRT973326	hsa-miR-4728-5p	CLIP-seq
MIRT973328	hsa-miR-4742-5p	CLIP-seq
MIRT973329	hsa-miR-4773	CLIP-seq
MIRT973331	hsa-miR-4789-3p	CLIP-seq
MIRT2222827	hsa-miR-4802-5p	CLIP-seq
MIRT973334	hsa-miR-501-3p	CLIP-seq
MIRT973335	hsa-miR-502-3p	CLIP-seq
MIRT973337	hsa-miR-508-5p	CLIP-seq
MIRT973340	hsa-miR-544b	CLIP-seq
MIRT973341	hsa-miR-548v	CLIP-seq
MIRT2222828	hsa-miR-550a	CLIP-seq
MIRT973344	hsa-miR-570	CLIP-seq
MIRT973346	hsa-miR-612	CLIP-seq
MIRT973347	hsa-miR-650	CLIP-seq
MIRT973349	hsa-miR-661	CLIP-seq
MIRT973350	hsa-miR-766	CLIP-seq
MIRT973351	hsa-miR-767-5p	CLIP-seq
MIRT973353	hsa-miR-92a	CLIP-seq
MIRT973354	hsa-miR-92b	CLIP-seq
MIRT1988376	hsa-miR-940	CLIP-seq
MIRT973235	hsa-miR-1228	CLIP-seq
MIRT973242	hsa-miR-1285	CLIP-seq
MIRT973256	hsa-miR-2114	CLIP-seq
MIRT973262	hsa-miR-25	CLIP-seq
MIRT973266	hsa-miR-3122	CLIP-seq
MIRT973270	hsa-miR-3136-3p	CLIP-seq
MIRT973272	hsa-miR-3165	CLIP-seq
MIRT973273	hsa-miR-3187-5p	CLIP-seq
MIRT973274	hsa-miR-32	CLIP-seq
MIRT973275	hsa-miR-338-3p	CLIP-seq
MIRT973279	hsa-miR-3612	CLIP-seq
MIRT973281	hsa-miR-3622a-3p	CLIP-seq
MIRT973282	hsa-miR-3622b-3p	CLIP-seq
MIRT973283	hsa-miR-363	CLIP-seq
MIRT973285	hsa-miR-3656	CLIP-seq
MIRT973286	hsa-miR-367	CLIP-seq
MIRT973289	hsa-miR-3689a-3p	CLIP-seq
MIRT973290	hsa-miR-3689c	CLIP-seq
MIRT973293	hsa-miR-3714	CLIP-seq
MIRT973294	hsa-miR-3913-5p	CLIP-seq
MIRT2222825	hsa-miR-3940-3p	CLIP-seq
MIRT973300	hsa-miR-4269	CLIP-seq
MIRT973304	hsa-miR-4325	CLIP-seq
MIRT973305	hsa-miR-4432	CLIP-seq
MIRT1988370	hsa-miR-4443	CLIP-seq
MIRT973306	hsa-miR-4459	CLIP-seq
MIRT973309	hsa-miR-4514	CLIP-seq
MIRT973310	hsa-miR-4530	CLIP-seq
MIRT2222826	hsa-miR-455-5p	CLIP-seq
MIRT973320	hsa-miR-4692	CLIP-seq
MIRT1988372	hsa-miR-4722-5p	CLIP-seq
MIRT973326	hsa-miR-4728-5p	CLIP-seq
MIRT973328	hsa-miR-4742-5p	CLIP-seq
MIRT973329	hsa-miR-4773	CLIP-seq
MIRT2222827	hsa-miR-4802-5p	CLIP-seq
MIRT973334	hsa-miR-501-3p	CLIP-seq
MIRT973335	hsa-miR-502-3p	CLIP-seq
MIRT973337	hsa-miR-508-5p	CLIP-seq
MIRT973340	hsa-miR-544b	CLIP-seq
MIRT2222828	hsa-miR-550a	CLIP-seq
MIRT973346	hsa-miR-612	CLIP-seq
MIRT973347	hsa-miR-650	CLIP-seq
MIRT973349	hsa-miR-661	CLIP-seq
MIRT973350	hsa-miR-766	CLIP-seq
MIRT973351	hsa-miR-767-5p	CLIP-seq
MIRT973353	hsa-miR-92a	CLIP-seq
MIRT973354	hsa-miR-92b	CLIP-seq
MIRT1988376	hsa-miR-940	CLIP-seq

Gene ontology (GO) Show/Hide all (35)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000176	Component	Nuclear exosome (RNase complex)	IBA
GO:0000176	Component	Nuclear exosome (RNase complex)	NAS	20531386
GO:0000177	Component	Cytoplasmic exosome (RNase complex)	IBA
GO:0000177	Component	Cytoplasmic exosome (RNase complex)	NAS	20531386
GO:0000178	Component	Exosome (RNase complex)	IDA	20531389
GO:0000178	Component	Exosome (RNase complex)	IEA
GO:0000178	Component	Exosome (RNase complex)	NAS	20531386
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IEA
GO:0004532	Function	RNA exonuclease activity	IDA	17174896
GO:0005634	Component	Nucleus	IDA	20531386
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA	20531386
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	20531386
GO:0005829	Component	Cytosol	TAS
GO:0006259	Process	DNA metabolic process	IEA
GO:0006364	Process	RRNA processing	IEA
GO:0006396	Process	RNA processing	IDA	17174896, 20531386
GO:0006396	Process	RNA processing	IEA
GO:0006401	Process	RNA catabolic process	IDA	17174896, 20531386
GO:0006401	Process	RNA catabolic process	IEA
GO:0016075	Process	RRNA catabolic process	IBA
GO:0034475	Process	U4 snRNA 3'-end processing	IBA
GO:0045006	Process	DNA deamination	IDA	21255825
GO:0045190	Process	Isotype switching	IEA
GO:0045190	Process	Isotype switching	ISS
GO:0045830	Process	Positive regulation of isotype switching	IEA
GO:0071028	Process	Nuclear mRNA surveillance	IBA
GO:0071051	Process	Poly(A)-dependent snoRNA 3'-end processing	IBA
GO:0101019	Component	Nucleolar exosome (RNase complex)	NAS	20531386

Other IDs

• MIM: 606490
• HGNC: 19055
• e!Ensembl: ENSG00000223496

Protein

• UniProt ID: Q5RKV6
• Protein name: Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)
• Protein function: Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturat
• PDB: 2NN6 , 6D6Q , 6D6R , 6H25 , 9G8N , 9G8O , 9G8P
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01138	RNase_PH	35 → 175		Domain

• Sequence:

  MPGDHRRIRGPEESQPPQLYAADEEEAPGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGT
  KVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRRAPFAGRRRRAPPGGCEER
  ELALALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGVEMYDLV
  VGCGLSLAPGPAPTWLLDPTRLEEERAAAGLTVALMPVLNQVAGLLGSGEGGLTESWAEA
  VRLGLEGCQRLYPVLQQSLVRAARRRGAAAQP

• Sequence length: 272

Pathways

KEGG Pathway	Reactome Pathway
RNA degradation	ATF4 activates genes in response to endoplasmic reticulum stress
	mRNA decay by 3' to 5' exoribonuclease
	Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
	Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
	KSRP (KHSRP) binds and destabilizes mRNA
	Major pathway of rRNA processing in the nucleolus and cytosol

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (29)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	26465153		★☆☆☆☆ Found in Text Mining only
Adrenoleukodystrophy	Adrenoleukodystrophy	BEFREE	18289715		★☆☆☆☆ Found in Text Mining only
Adult Acute Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	26465153		★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety Disorder	BEFREE	19815710, 31337969		★☆☆☆☆ Found in Text Mining only
Anxiety Disorders	Anxiety Disorder	BEFREE	19815710, 31337969		★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	BEFREE	19380152, 21722919		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	17203189		★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	BEFREE	26465153		★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	16400147, 17510952, 18838110, 19380152, 19702551, 20962329, 21367534, 22990943, 26821757, 27457815, 28137881, 28507317, 29550211, 30617637, 31337969		★☆☆☆☆ Found in Text Mining only
Hematological Disease	Hematological Disease	BEFREE	3971322		★☆☆☆☆ Found in Text Mining only
Hereditary liability to pressure palsies	Hereditary Liability To Pressure Palsies	BEFREE	8565626		★☆☆☆☆ Found in Text Mining only
Hydrocephalus	Hydrocephalus	BEFREE	31771992		★☆☆☆☆ Found in Text Mining only
Irritable Bowel Syndrome	Irritable Bowel Syndrome	BEFREE	17241856		★☆☆☆☆ Found in Text Mining only
Major Depressive Disorder	Mental Depression	BEFREE	17510952, 18838110, 19380152, 20863517, 27616678, 29334322, 29353887		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	17203189		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	25602368		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	16400147, 17510952, 18838110, 19380152, 19702551, 20962329, 21367534, 22990943, 26821757, 27457815, 28137881, 28507317, 29550211, 30617637, 31337969		★☆☆☆☆ Found in Text Mining only
Mental disorders	Mental Disorders	BEFREE	19380152, 20863517		★☆☆☆☆ Found in Text Mining only
Motor neuron atrophy	Motor neuron atrophy	BEFREE	31439839		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	25602368, 31028568		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	25841787		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	21093564		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	28137881		★☆☆☆☆ Found in Text Mining only
Post-Traumatic Stress Disorder	Stress Disorder	BEFREE	18440154, 19380152, 20863517		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	BEFREE	17317953		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	19380152		★☆☆☆☆ Found in Text Mining only
Smith-Magenis syndrome	Smith-Magenis Syndrome	BEFREE	8565626		★☆☆☆☆ Found in Text Mining only
Thyroid carcinoma	Thyroid Carcinoma	BEFREE	31028568		★☆☆☆☆ Found in Text Mining only
Unipolar Depression	Mental Depression	BEFREE	18838110, 19380152		★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

EXOSC8 7 shared pathwaysRNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol, mRNA decay by 3' to 5' exoribonuclease, ATF4 activates genes in response to endoplasmic reticulum stress, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA, KSRP (KHSRP) binds and destabilizes mRNA Related via 7 shared pathways including RNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol. DIS3 7 shared pathwaysRNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol, mRNA decay by 3' to 5' exoribonuclease, ATF4 activates genes in response to endoplasmic reticulum stress, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA, KSRP (KHSRP) binds and destabilizes mRNA Related via 7 shared pathways including RNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol. EXOSC7 7 shared pathwaysRNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol, mRNA decay by 3' to 5' exoribonuclease, ATF4 activates genes in response to endoplasmic reticulum stress, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA, KSRP (KHSRP) binds and destabilizes mRNA Related via 7 shared pathways including RNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol. EXOSC2 7 shared pathwaysRNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol, mRNA decay by 3' to 5' exoribonuclease, ATF4 activates genes in response to endoplasmic reticulum stress, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA, KSRP (KHSRP) binds and destabilizes mRNA Related via 7 shared pathways including RNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol. EXOSC3 7 shared pathwaysRNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol, mRNA decay by 3' to 5' exoribonuclease, ATF4 activates genes in response to endoplasmic reticulum stress, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA, KSRP (KHSRP) binds and destabilizes mRNA Related via 7 shared pathways including RNA degradation, Major pathway of rRNA processing in the nucleolus and cytosol.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
EXOSC8	0	[]	7	["RNA degradation","Major pathway of rRNA processing in the nucleolus and cytosol","mRNA decay by 3' to 5' exoribonuclease","ATF4 activates genes in response to endoplasmic reticulum stress","Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA","Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA","KSRP (KHSRP) binds and destabilizes mRNA"]	0	[]
DIS3	0	[]	7	["RNA degradation","Major pathway of rRNA processing in the nucleolus and cytosol","mRNA decay by 3' to 5' exoribonuclease","ATF4 activates genes in response to endoplasmic reticulum stress","Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA","Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA","KSRP (KHSRP) binds and destabilizes mRNA"]	0	[]
EXOSC7	0	[]	7	["RNA degradation","Major pathway of rRNA processing in the nucleolus and cytosol","mRNA decay by 3' to 5' exoribonuclease","ATF4 activates genes in response to endoplasmic reticulum stress","Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA","Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA","KSRP (KHSRP) binds and destabilizes mRNA"]	0	[]
EXOSC2	0	[]	7	["RNA degradation","Major pathway of rRNA processing in the nucleolus and cytosol","mRNA decay by 3' to 5' exoribonuclease","ATF4 activates genes in response to endoplasmic reticulum stress","Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA","Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA","KSRP (KHSRP) binds and destabilizes mRNA"]	0	[]
EXOSC3	0	[]	7	["RNA degradation","Major pathway of rRNA processing in the nucleolus and cytosol","mRNA decay by 3' to 5' exoribonuclease","ATF4 activates genes in response to endoplasmic reticulum stress","Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA","Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA","KSRP (KHSRP) binds and destabilizes mRNA"]	0	[]

Diseases Linked via Similar Genes

Congenital pontocerebellar hypoplasia Linked via 2 of 5 related genesEXOSC8, EXOSC3 Pontocerebellar hypoplasia Linked via 2 of 5 related genesEXOSC8, EXOSC3 Spastic ataxia Linked via 1 of 5 related genesEXOSC8 Prostate cancer Linked via 1 of 5 related genesDIS3 Color vision deficiency Linked via 1 of 5 related genesEXOSC2

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Congenital pontocerebellar hypoplasia	2	["EXOSC8","EXOSC3"]
Pontocerebellar hypoplasia	2	["EXOSC8","EXOSC3"]
Spastic ataxia	1	["EXOSC8"]
Prostate cancer	1	["DIS3"]
Color vision deficiency	1	["EXOSC2"]