Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	245938
Gene name	Defensin beta 125
Gene symbol	DEFB125
Synonyms (NCBI Gene)	DEFB-25
Chromosome	20
Chromosome location	20p13
Summary	Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin

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miRTarBase ID	miRNA	Experiments	Reference
MIRT023886	hsa-miR-1-3p	Microarray	18668037
MIRT931942	hsa-miR-125a-5p	CLIP-seq
MIRT931943	hsa-miR-125b	CLIP-seq
MIRT931944	hsa-miR-1343	CLIP-seq
MIRT931945	hsa-miR-3074-5p	CLIP-seq
MIRT931946	hsa-miR-3134	CLIP-seq
MIRT931947	hsa-miR-4299	CLIP-seq
MIRT931948	hsa-miR-4319	CLIP-seq
MIRT931949	hsa-miR-4534	CLIP-seq
MIRT931950	hsa-miR-4732-3p	CLIP-seq
MIRT931951	hsa-miR-670	CLIP-seq

GO ID	Ontology	Definition	Evidence
GO:0005576	Component	Extracellular region	IEA
GO:0006952	Process	Defense response	IEA
GO:0042742	Process	Defense response to bacterium	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0050829	Process	Defense response to Gram-negative bacterium	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q8N687

Protein name

Beta-defensin 125 (Beta-defensin 25) (DEFB-25) (Defensin, beta 125)

Protein function

Has antibacterial activity.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13841	Defensin_beta_2	26 → 56	Beta defensin	Domain

Sequence

MNILMLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISII
SHEYTRRPAFPVIHLEDITLDYSDVDSFTGSPVSMLNDLITFDTTKFGETMTPETNTPET
TMPPSEATTPETTMPPSETATSETMPPPSQTALTHN

Sequence length

156

Interactions

View interactions

Reactome Pathway
Beta defensins
Defensins

DEFB125 (defensin beta 125)

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