DEFB105B (defensin beta 105B)

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Gene miRNA Gene ontology Other IDs Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 504180
• Gene name: Defensin beta 105B
• Gene symbol: DEFB105B
• Synonyms (NCBI Gene): BD-5, DEFB-5
• Chromosome: 8
• Chromosome location: 8p23.1
• Summary: Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensi

miRNA Show/Hide all (138)

miRTarBase ID	miRNA	Experiments	Reference
MIRT718224	hsa-miR-4524b-3p	HITS-CLIP	19536157
MIRT718223	hsa-miR-4729	HITS-CLIP	19536157
MIRT718222	hsa-miR-1468-3p	HITS-CLIP	19536157
MIRT637489	hsa-miR-4797-5p	HITS-CLIP	23313552
MIRT637488	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT637487	hsa-miR-5586-3p	HITS-CLIP	23313552
MIRT637485	hsa-miR-759	HITS-CLIP	23313552
MIRT637484	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT637483	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT637482	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT637481	hsa-miR-1237-3p	HITS-CLIP	23313552
MIRT637480	hsa-miR-1248	HITS-CLIP	23313552
MIRT637474	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT637473	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT637472	hsa-miR-4486	HITS-CLIP	23313552
MIRT637471	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT637470	hsa-miR-4252	HITS-CLIP	23313552
MIRT637469	hsa-miR-661	HITS-CLIP	23313552
MIRT637468	hsa-miR-1273a	HITS-CLIP	23313552
MIRT637467	hsa-miR-4649-5p	HITS-CLIP	23313552
MIRT637466	hsa-miR-6729-5p	HITS-CLIP	23313552
MIRT637465	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT637464	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT637463	hsa-miR-6868-3p	HITS-CLIP	23313552
MIRT637462	hsa-miR-513c-5p	HITS-CLIP	23313552
MIRT637461	hsa-miR-514b-5p	HITS-CLIP	23313552
MIRT637460	hsa-miR-3672	HITS-CLIP	23313552
MIRT637459	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT637458	hsa-miR-7703	HITS-CLIP	23313552
MIRT637489	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT637488	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT637487	hsa-miR-5586-3p	HITS-CLIP	23824327
MIRT637486	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT637485	hsa-miR-759	HITS-CLIP	23824327
MIRT637484	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT637483	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT637482	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT637481	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT637480	hsa-miR-1248	HITS-CLIP	23824327
MIRT637479	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT637478	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT637477	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT637476	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT637475	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT637474	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT637473	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT637472	hsa-miR-4486	HITS-CLIP	23824327
MIRT637471	hsa-miR-873-3p	HITS-CLIP	23824327
MIRT637470	hsa-miR-4252	HITS-CLIP	23824327
MIRT637469	hsa-miR-661	HITS-CLIP	23824327
MIRT637468	hsa-miR-1273a	HITS-CLIP	23824327
MIRT637467	hsa-miR-4649-5p	HITS-CLIP	23824327
MIRT637466	hsa-miR-6729-5p	HITS-CLIP	23824327
MIRT637465	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT637464	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT637463	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT637462	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT637461	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT637460	hsa-miR-3672	HITS-CLIP	23824327
MIRT637459	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT637458	hsa-miR-7703	HITS-CLIP	23824327
MIRT619818	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT619817	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT619816	hsa-miR-3612	HITS-CLIP	23824327
MIRT619815	hsa-miR-650	HITS-CLIP	23824327
MIRT619814	hsa-miR-7977	HITS-CLIP	23824327
MIRT619813	hsa-miR-4443	HITS-CLIP	23824327
MIRT619812	hsa-miR-6515-5p	HITS-CLIP	23824327
MIRT619811	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT718224	hsa-miR-4524b-3p	HITS-CLIP	19536157
MIRT718223	hsa-miR-4729	HITS-CLIP	19536157
MIRT718222	hsa-miR-1468-3p	HITS-CLIP	19536157
MIRT637489	hsa-miR-4797-5p	HITS-CLIP	23313552
MIRT637488	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT637487	hsa-miR-5586-3p	HITS-CLIP	23313552
MIRT637485	hsa-miR-759	HITS-CLIP	23313552
MIRT637484	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT637483	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT637482	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT637481	hsa-miR-1237-3p	HITS-CLIP	23313552
MIRT637480	hsa-miR-1248	HITS-CLIP	23313552
MIRT637474	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT637473	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT637472	hsa-miR-4486	HITS-CLIP	23313552
MIRT637471	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT637470	hsa-miR-4252	HITS-CLIP	23313552
MIRT637469	hsa-miR-661	HITS-CLIP	23313552
MIRT637468	hsa-miR-1273a	HITS-CLIP	23313552
MIRT637467	hsa-miR-4649-5p	HITS-CLIP	23313552
MIRT637466	hsa-miR-6729-5p	HITS-CLIP	23313552
MIRT637465	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT637464	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT637463	hsa-miR-6868-3p	HITS-CLIP	23313552
MIRT637462	hsa-miR-513c-5p	HITS-CLIP	23313552
MIRT637461	hsa-miR-514b-5p	HITS-CLIP	23313552
MIRT637460	hsa-miR-3672	HITS-CLIP	23313552
MIRT637459	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT637458	hsa-miR-7703	HITS-CLIP	23313552
MIRT637489	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT637488	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT637487	hsa-miR-5586-3p	HITS-CLIP	23824327
MIRT637486	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT637485	hsa-miR-759	HITS-CLIP	23824327
MIRT637484	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT637483	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT637482	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT637481	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT637480	hsa-miR-1248	HITS-CLIP	23824327
MIRT637479	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT637478	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT637477	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT637476	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT637475	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT637474	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT637473	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT637472	hsa-miR-4486	HITS-CLIP	23824327
MIRT637471	hsa-miR-873-3p	HITS-CLIP	23824327
MIRT637470	hsa-miR-4252	HITS-CLIP	23824327
MIRT637469	hsa-miR-661	HITS-CLIP	23824327
MIRT637468	hsa-miR-1273a	HITS-CLIP	23824327
MIRT637467	hsa-miR-4649-5p	HITS-CLIP	23824327
MIRT637466	hsa-miR-6729-5p	HITS-CLIP	23824327
MIRT637465	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT637464	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT637463	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT637462	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT637461	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT637460	hsa-miR-3672	HITS-CLIP	23824327
MIRT637459	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT637458	hsa-miR-7703	HITS-CLIP	23824327
MIRT619818	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT619817	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT619816	hsa-miR-3612	HITS-CLIP	23824327
MIRT619815	hsa-miR-650	HITS-CLIP	23824327
MIRT619814	hsa-miR-7977	HITS-CLIP	23824327
MIRT619813	hsa-miR-4443	HITS-CLIP	23824327
MIRT619812	hsa-miR-6515-5p	HITS-CLIP	23824327
MIRT619811	hsa-miR-7850-5p	HITS-CLIP	23824327

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005576	Component	Extracellular region	IEA
GO:0006952	Process	Defense response	IEA
GO:0042742	Process	Defense response to bacterium	IEA
GO:0045087	Process	Innate immune response	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Interactions View interactions

Pathways

Reactome Pathway

Beta defensins

Defensins

Related Genes

Sort by: Blended Diseases Pathways Evidence source

DEFB130B 2 shared pathwaysBeta defensins, Defensins Related via 2 shared pathways including Beta defensins, Defensins. DEFB118 2 shared pathwaysBeta defensins, Defensins Related via 2 shared pathways including Beta defensins, Defensins. DEFB104A 2 shared pathwaysBeta defensins, Defensins Related via 2 shared pathways including Beta defensins, Defensins. DEFB127 2 shared pathwaysBeta defensins, Defensins Related via 2 shared pathways including Beta defensins, Defensins. DEFB129 2 shared pathwaysBeta defensins, Defensins Related via 2 shared pathways including Beta defensins, Defensins.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
DEFB130B	0	[]	2	["Beta defensins","Defensins"]	0	[]
DEFB118	0	[]	2	["Beta defensins","Defensins"]	0	[]
DEFB104A	0	[]	2	["Beta defensins","Defensins"]	0	[]
DEFB127	0	[]	2	["Beta defensins","Defensins"]	0	[]
DEFB129	0	[]	2	["Beta defensins","Defensins"]	0	[]

Diseases Linked via Similar Genes

Insomnia Linked via 1 of 5 related genesDEFB118 Coronary artery disease Linked via 1 of 5 related genesDEFB127 Obesity Linked via 1 of 5 related genesDEFB127 Obstructive sleep apnea syndrome Linked via 1 of 5 related genesDEFB127 Hirschsprung disease Linked via 1 of 5 related genesDEFB129

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Insomnia	1	["DEFB118"]
Coronary artery disease	1	["DEFB127"]
Obesity	1	["DEFB127"]
Obstructive sleep apnea syndrome	1	["DEFB127"]
Hirschsprung disease	1	["DEFB129"]