Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	53842
Gene name	Claudin 22
Gene symbol	CLDN22
Synonyms (NCBI Gene)	CLDN21
Chromosome	4
Chromosome location	4q35.1
Summary	This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellula

79 Show/Hide all (79)

miRTarBase ID	miRNA	Experiments
MIRT895262	hsa-miR-1254	CLIP-seq
MIRT895263	hsa-miR-1305	CLIP-seq
MIRT895264	hsa-miR-148a	CLIP-seq
MIRT895265	hsa-miR-148b	CLIP-seq
MIRT895266	hsa-miR-152	CLIP-seq
MIRT895267	hsa-miR-3116	CLIP-seq
MIRT895268	hsa-miR-3613-3p	CLIP-seq
MIRT895269	hsa-miR-4330	CLIP-seq
MIRT895270	hsa-miR-4494	CLIP-seq
MIRT895271	hsa-miR-4646-5p	CLIP-seq
MIRT895272	hsa-miR-4731-3p	CLIP-seq
MIRT895273	hsa-miR-4747-5p	CLIP-seq
MIRT895274	hsa-miR-4786-3p	CLIP-seq
MIRT895275	hsa-miR-4801	CLIP-seq
MIRT895276	hsa-miR-499a-5p	CLIP-seq
MIRT895277	hsa-miR-502-5p	CLIP-seq
MIRT895278	hsa-miR-515-3p	CLIP-seq
MIRT895279	hsa-miR-519e	CLIP-seq
MIRT895280	hsa-miR-522	CLIP-seq
MIRT895281	hsa-miR-548c-3p	CLIP-seq
MIRT895282	hsa-miR-550a	CLIP-seq
MIRT895283	hsa-miR-577	CLIP-seq
MIRT895284	hsa-miR-586	CLIP-seq
MIRT895285	hsa-miR-607	CLIP-seq
MIRT895286	hsa-miR-661	CLIP-seq
MIRT895287	hsa-miR-671-5p	CLIP-seq
MIRT1965470	hsa-miR-376c	CLIP-seq
MIRT1965471	hsa-miR-3921	CLIP-seq
MIRT1965472	hsa-miR-3976	CLIP-seq
MIRT1965473	hsa-miR-3978	CLIP-seq
MIRT1965474	hsa-miR-4653-5p	CLIP-seq
MIRT1965475	hsa-miR-499-3p	CLIP-seq
MIRT1965476	hsa-miR-499a-3p	CLIP-seq
MIRT1965477	hsa-miR-587	CLIP-seq
MIRT1965478	hsa-miR-593	CLIP-seq
MIRT895262	hsa-miR-1254	CLIP-seq
MIRT895264	hsa-miR-148a	CLIP-seq
MIRT895265	hsa-miR-148b	CLIP-seq
MIRT895266	hsa-miR-152	CLIP-seq
MIRT2201414	hsa-miR-3074-3p	CLIP-seq
MIRT895267	hsa-miR-3116	CLIP-seq
MIRT2201415	hsa-miR-3149	CLIP-seq
MIRT2201416	hsa-miR-361-5p	CLIP-seq
MIRT2201417	hsa-miR-4325	CLIP-seq
MIRT895271	hsa-miR-4646-5p	CLIP-seq
MIRT2201418	hsa-miR-4716-5p	CLIP-seq
MIRT895273	hsa-miR-4747-5p	CLIP-seq
MIRT895274	hsa-miR-4786-3p	CLIP-seq
MIRT2201419	hsa-miR-4793-3p	CLIP-seq
MIRT895278	hsa-miR-515-3p	CLIP-seq
MIRT895279	hsa-miR-519e	CLIP-seq
MIRT895282	hsa-miR-550a	CLIP-seq
MIRT2201420	hsa-miR-568	CLIP-seq
MIRT1965477	hsa-miR-587	CLIP-seq
MIRT2201421	hsa-miR-595	CLIP-seq
MIRT895286	hsa-miR-661	CLIP-seq
MIRT895287	hsa-miR-671-5p	CLIP-seq
MIRT2201422	hsa-miR-767-3p	CLIP-seq
MIRT2447144	hsa-miR-143	CLIP-seq
MIRT2447145	hsa-miR-3920	CLIP-seq
MIRT1965471	hsa-miR-3921	CLIP-seq
MIRT2447146	hsa-miR-4428	CLIP-seq
MIRT1965474	hsa-miR-4653-5p	CLIP-seq
MIRT2447147	hsa-miR-4770	CLIP-seq
MIRT1965478	hsa-miR-593	CLIP-seq
MIRT2447144	hsa-miR-143	CLIP-seq
MIRT2447145	hsa-miR-3920	CLIP-seq
MIRT1965471	hsa-miR-3921	CLIP-seq
MIRT2447146	hsa-miR-4428	CLIP-seq
MIRT1965474	hsa-miR-4653-5p	CLIP-seq
MIRT2447147	hsa-miR-4770	CLIP-seq
MIRT1965478	hsa-miR-593	CLIP-seq
MIRT2447144	hsa-miR-143	CLIP-seq
MIRT2447145	hsa-miR-3920	CLIP-seq
MIRT1965471	hsa-miR-3921	CLIP-seq
MIRT2447146	hsa-miR-4428	CLIP-seq
MIRT1965474	hsa-miR-4653-5p	CLIP-seq
MIRT2447147	hsa-miR-4770	CLIP-seq
MIRT1965478	hsa-miR-593	CLIP-seq

13 Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005198	Function	Structural molecule activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005923	Component	Bicellular tight junction	IBA
GO:0005923	Component	Bicellular tight junction	IEA
GO:0005923	Component	Bicellular tight junction	ISS
GO:0007155	Process	Cell adhesion	IBA
GO:0016020	Component	Membrane	IEA
GO:0016338	Process	Calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	ISS
GO:0042802	Function	Identical protein binding	ISS
GO:0070161	Component	Anchoring junction	IEA
GO:0070830	Process	Bicellular tight junction assembly	IBA

MIM	HGNC	e!Ensembl
620566	2044	ENSG00000177300

Q8N7P3

Protein name

Claudin-22

Protein function

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00822	PMP22_Claudin	7 → 183	PMP-22/EMP/MP20/Claudin family	Family

Sequence

MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
CLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH

Sequence length

220

Interactions

View interactions

KEGG Pathway
Virion - Hepatitis viruses
Cell adhesion molecules
Tight junction
Leukocyte transendothelial migration
Pathogenic Escherichia coli infection
Hepatitis C

CLDN22 (claudin 22)

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