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Gene Gene information from NCBI Gene database.
Entrez ID 8760
Gene name CDP-diacylglycerol synthase 2
Gene symbol CDS2
Synonyms (NCBI Gene)
-
Chromosome 20
Chromosome location 20p12.3
Summary Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzy
miRNA miRNA information provided by mirtarbase database.
952 Show/Hide all (952)
miRTarBase ID miRNA Experiments Reference
MIRT032053 hsa-miR-16-5p Microarray 21199864
MIRT044394 hsa-miR-320a CLASH 23622248
MIRT041676 hsa-miR-484 CLASH 23622248
MIRT032053 hsa-miR-16-5p Luciferase reporter assayWestern blotMicroarrayqRT-PCR 23941513
MIRT032053 hsa-miR-16-5p Luciferase reporter assayWestern blotMicroarrayqRT-PCR 23941513
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23 Show/Hide all (23)
GO ID Ontology Definition Evidence Reference
GO:0004605 Function Phosphatidate cytidylyltransferase activity IDA 25375833
GO:0004605 Function Phosphatidate cytidylyltransferase activity IEA
GO:0004605 Function Phosphatidate cytidylyltransferase activity NAS 9806839
GO:0004605 Function Phosphatidate cytidylyltransferase activity TAS
GO:0005515 Function Protein binding IPI 32296183, 32814053, 33961781, 35271311, 35384245
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603549 1801 ENSG00000101290
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O95674
Protein name Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-DAG synthase 2) (CDP-DG synthase 2) (CDP-diacylglycerol synthase 2) (CDS 2) (CDP-diglyceride pyrophosphorylase 2) (CDP-diglyceride synthase 2) (CTP:phosphatidate cytidylyltransferase 2)
Protein function Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol (PubMed:25375833). Exhibits specificity for the nature o
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01148 CTP_transf_1 70 → 400 Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Expressed in heart, brain and retina, and to a lesser extent in placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9889000}.
Sequence
Sequence length 445
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Glycerophospholipid metabolism Synthesis of PG
Metabolic pathways  
Phosphatidylinositol signaling system