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Polycystic kidney disease 3 with or without polycystic liver disease
Polycystic kidney disease 3 with or without polycystic liver disease
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
Polycystic kidney disease 3 with or without polycystic liver disease
600666
C3887964
MONDO:0010916
MONDO_0054743
GANAB
Causal
33097077
27259053
ClinGen
N-Glycan biosynthesis
Metabolic pathways
Protein processing in endoplasmic reticulum
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Calnexin/calreticulin cycle
+2 more
ALG8
Unknown
15235028
28375157
30135240
Open Targets
N-Glycan biosynthesis
Metabolic pathways
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Defective ALG8 causes ALG8-CDG (CDG-1h)
+1 more
All
2
Causal
1
Unknown
1
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
1
Open Targets
1
Related Diseases
Diseases that share the most curated genes with Polycystic kidney disease 3 with or without polycystic liver disease.
5
View disease cluster →
Autosomal dominant polycystic kidney disease
1 shared gene
ALG8
Related via 1 shared gene including ALG8.
Polycystic liver disease
2 shared genes
ALG8, GANAB
Related via 2 shared genes including ALG8, GANAB.
Polycystic kidney disease
2 shared genes
ALG8, GANAB
Related via 2 shared genes including ALG8, GANAB.
Cystic kidney disease
1 shared gene
ALG8
Related via 1 shared gene including ALG8.
Congenital disorder of glycosylation
1 shared gene
ALG8
Related via 1 shared gene including ALG8.
1
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