Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
plasma cell myeloma	MONDO_0009693	LMO1	Unknown	24434212	Open Targets	RUNX1 regulates transcription of genes involved in differentiation of HSCs
		LMO2	Unknown	30545397 24434212	Open Targets	Transcriptional misregulation in cancer RUNX1 regulates transcription of genes involved in differentiation of HSCs
		LOC100506403	Unknown	24434212	Open Targets	—
		LOC105376156	Unknown	24434212	Open Targets	—
		LOC124905021	Unknown	24434212	Open Targets	—
		LPP	Unknown	30545397 24434212	Open Targets	—
		LRIG3	Unknown	30545397 24434212	Open Targets	—
		LRP1B	Unknown	36251745 25743686 24434212 35045690 22573403 23396385	Open Targets	—
		LSM14A	Unknown	30545397 24434212	Open Targets	—
		LYL1	Unknown	35045690	Open Targets	Transcriptional misregulation in cancer NGF-stimulated transcription
		LYN	Unknown	30545397 24434212	Open Targets	Chemokine signaling pathway NF-kappa B signaling pathway Platelet activation +36 more
		LZTR1	Unknown	35045690 30545397 22573403 24434212	Open Targets	—
		MACC1	Unknown	30545397 24434212	Open Targets	—
		MAF	Unknown	30545397 29563506 24434212	Open Targets	Th1 and Th2 cell differentiation Transcriptional misregulation in cancer Inflammatory bowel disease
		MAFB	Unknown	26918361 24434212	Open Targets	Parathyroid hormone synthesis, secretion and action
		MALT1	Unknown	30545397 22573403 24434212	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		MAML2	Unknown	24434212	Open Targets	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MAP2K1	Unknown	35396243 24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MAP2K2	Unknown	23396385 24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +87 more
		MAP2K4	Unknown	24434212	Open Targets	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway +21 more
		MAP3K1	Unknown	35045690 30545397 24434212	Open Targets	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K13	Unknown	24434212	Open Targets	MAPK signaling pathway
		MAPK1	Unknown	24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +161 more
		MAX	Unknown	24434212 30545397 35045690 29563506 22573403 26918361	Open Targets	Polycomb repressive complex MAPK signaling pathway Pathways in cancer +6 more
		MB21D2	Unknown	35045690 30545397 24434212	Open Targets	—
		MDM2	Unknown	35045690 30545397 24434212	Open Targets	Endocrine resistance Platinum drug resistance FoxO signaling pathway +35 more
		MDM4	Unknown	30545397 24434212	Open Targets	p53 signaling pathway MicroRNAs in cancer Oxidative Stress Induced Senescence +6 more
		MECOM	Unknown	25743686 35045690 30545397 23396385 24434212	Open Targets	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MED12	Unknown	30545397 35045690 29563506 24434212	Open Targets	Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway +1 more
		MET	Unknown	30545397 24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		MGMT	Unknown	35045690 30545397 24434212	Open Targets	MGMT-mediated DNA damage reversal
		MITF	Unknown	35045690 30545397 24434212	Open Targets	Mitophagy - animal Osteoclast differentiation Melanogenesis +4 more
		MLF1	Unknown	30545397 24434212	Open Targets	Transcriptional misregulation in cancer
		MLH1	Unknown	25794135 29563506 24434212 30545397	Open Targets	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MLLT1	Unknown	24434212	Open Targets	Viral life cycle - HIV-1 Transcriptional misregulation in cancer Formation of RNA Pol II elongation complex +2 more
		MLLT10	Unknown	30545397 24434212	Open Targets	—
		MLLT11	Unknown	24434212	Open Targets	—
		MLLT3	Unknown	30545397 29563506 24434212	Open Targets	Viral life cycle - HIV-1 Transcriptional misregulation in cancer Formation of RNA Pol II elongation complex +2 more
		MN1	Unknown	24434212	Open Targets	—
		MNX1	Unknown	30545397	Open Targets	Maturity onset diabetes of the young
		MPL	Unknown	24434212	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling JAK-STAT signaling pathway
		MRTFA	Unknown	30545397 24434212	Open Targets	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSH2	Unknown	30545397 29563506 24434212	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +7 more
		MSH6	Unknown	30545397 35045690 29563506 24434212	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +4 more
		MSI2	Unknown	30545397 24434212	Open Targets	mRNA surveillance pathway
		MSN	Unknown	35045690 24434212	Open Targets	Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton +4 more
		MTCP1	Unknown	29386642 24434212	Open Targets	PI3K-Akt signaling pathway
		MTOR	Unknown	30545397 29563506 24434212	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +61 more
		MUC1	Unknown	24434212	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +4 more
		MUC16	Unknown	35045690 23396385 22573403 24434212	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more

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Plasma cell myeloma

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