Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
peripheral T-cell lymphoma, not otherwise specified	MONDO_0004964	ABL1	Unknown	28481359	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		AKT1	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		AKT2	Unknown	27203213	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +122 more
		ALK	Unknown	8701987 7662979 8558920 8781434 8781433 11178628 28481359 7579458	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		APC	Unknown	25257991	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AR	Unknown	27203213	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARAF	Unknown	27203213	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +41 more
		ARID1A	Unknown	28481359	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID1B	Unknown	27203213 25257991 29305415	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	27203213 25257991 29305415	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ASXL1	Unknown	28481359	Open Targets	Polycomb repressive complex UCH proteinases
		ASXL2	Unknown	28481359	Open Targets	Polycomb repressive complex UCH proteinases
		ATM	Unknown	25257991 24413734 12697903	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		B2M	Unknown	27203213	Open Targets	Antigen processing and presentation Human cytomegalovirus infection Human T-cell leukemia virus 1 infection +14 more
		BCL11A	Unknown	24413734	Open Targets	—
		BCL11B	Unknown	27203213	Open Targets	Transcriptional misregulation in cancer
		BCL6	Unknown	25257991	Open Targets	FoxO signaling pathway Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation +3 more
		BCL9	Unknown	25257991	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCORL1	Unknown	25257991	Open Targets	Polycomb repressive complex
		BCR	Unknown	27203213	Open Targets	Pathways in cancer Chronic myeloid leukemia Signaling by cytosolic FGFR1 fusion mutants +2 more
		BIRC6	Unknown	24413734	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BRAF	Unknown	27203213	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA2	Unknown	27203213 25257991	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRD3	Unknown	27203213	Open Targets	—
		BRD4	Unknown	25257991 28481359	Open Targets	—
		BRIP1	Unknown	25257991	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		CARD11	Unknown	27203213 29662631	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CCND3	Unknown	27203213	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +17 more
		CCNE1	Unknown	27203213	Open Targets	Cell cycle Oocyte meiosis p53 signaling pathway +24 more
		CD79A	Unknown	27203213 28481359	Open Targets	B cell receptor signaling pathway Primary immunodeficiency CD22 mediated BCR regulation +1 more
		CDH1	Unknown	27203213	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		CDH10	Unknown	24413734	Open Targets	Adherens junctions interactions
		CDK4	Unknown	27203213	Open Targets	Endocrine resistance Cell cycle p53 signaling pathway +40 more
		CDKN2A	Unknown	11021747 27203213 7632961 24413734 21356189	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CEBPA	Unknown	27203213	Open Targets	Non-alcoholic fatty liver disease Pathways in cancer Transcriptional misregulation in cancer +3 more
		CIITA	Unknown	27203213 25257991	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CREBBP	Unknown	27203213 25257991 29305415	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CSF1R	Unknown	27203213	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CSMD3	Unknown	24413734	Open Targets	—
		CTCF	Unknown	27203213	Open Targets	—
		CTNNB1	Unknown	18757411 11896204	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CUL3	Unknown	27203213	Open Targets	Ubiquitin mediated proteolysis Hedgehog signaling pathway Degradation of DVL +4 more
		DCC	Unknown	24413734	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DDX3X	Unknown	25257991	Open Targets	RIG-I-like receptor signaling pathway Hepatitis B Viral carcinogenesis +1 more
		DICER1	Unknown	27203213	Open Targets	MicroRNAs in cancer MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
		DNM2	Unknown	24413734	Open Targets	Phospholipase D signaling pathway Endocytosis Fc gamma R-mediated phagocytosis +13 more
		DNMT3A	Unknown	31394087 24413737 29662631 22216861 29305415 27203213 29386642 25257991 28481359 26268241	Open Targets	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		EGFR	Unknown	27203213 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		EP300	Unknown	27203213 29305415	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +66 more
		EPHA3	Unknown	28481359	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more

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Peripheral t-cell lymphoma, not otherwise specified

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