Subtype of: Pancreatic neoplasms

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
pancreatic neuroendocrine tumor	MONDO_0019954	ABL1	Unknown	28481359	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ACVR2A	Unknown	29092957	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +3 more
		AFDN	Unknown	26087898	Open Targets	Ras signaling pathway Rap1 signaling pathway cAMP signaling pathway +4 more
		AKT1	Unknown	27994516	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		AKT2	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +122 more
		AMER1	Unknown	28481359	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		APC	Unknown	23354304 26087898 32586046 28481359	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AR	Unknown	32586046	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARID1A	Unknown	29092957 32586046 28481359 27994516	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID1B	Unknown	28481359	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	32586046 28481359	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ASXL1	Unknown	26087898	Open Targets	Polycomb repressive complex UCH proteinases
		ASXL2	Unknown	28481359	Open Targets	Polycomb repressive complex UCH proteinases
		ATM	Unknown	27994516 26087898 32586046 28481359 21447618	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATRX	Unknown	27994516 32586046 29092957 21252315 28481359	Open Targets	Cell cycle
		AXIN1	Unknown	28481359	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AXIN2	Unknown	28481359	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BARD1	Unknown	28481359	Open Targets	Homologous recombination HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +11 more
		BCL6	Unknown	28481359	Open Targets	FoxO signaling pathway Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation +3 more
		BCL9	Unknown	32586046	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCL9L	Unknown	21252315	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCOR	Unknown	28481359	Open Targets	Polycomb repressive complex
		BCORL1	Unknown	29092957	Open Targets	Polycomb repressive complex
		BCR	Unknown	32586046	Open Targets	Pathways in cancer Chronic myeloid leukemia Signaling by cytosolic FGFR1 fusion mutants +2 more
		BLM	Unknown	32586046 28481359	Open Targets	Homologous recombination Fanconi anemia pathway Processive synthesis on the C-strand of the telomere +10 more
		BMPR1A	Unknown	28481359	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling TGF-beta signaling pathway +4 more
		BRAF	Unknown	19003996 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA2	Unknown	29092957 28481359	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRD4	Unknown	28481359	Open Targets	—
		BRIP1	Unknown	28481359	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		CARD11	Unknown	28481359	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CBL	Unknown	28481359	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +22 more
		CCNC	Unknown	29092957	Open Targets	PPARA activates gene expression Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription +3 more
		CCND1	Unknown	28481359	Open Targets	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CD79B	Unknown	28481359	Open Targets	B cell receptor signaling pathway CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
		CDH1	Unknown	32586046 28481359	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		CDH10	Unknown	29092957	Open Targets	Adherens junctions interactions
		CDK12	Unknown	28481359	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDKN1B	Unknown	28481359	Open Targets	Endocrine resistance ErbB signaling pathway HIF-1 signaling pathway +28 more
		COL1A1	Unknown	32586046 21252315	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		CREBBP	Unknown	32586046 28481359	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRLF2	Unknown	28481359	Open Targets	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Interleukin-7 signaling
		CSF1R	Unknown	32586046 28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CSF3R	Unknown	28481359	Open Targets	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway JAK-STAT signaling pathway +3 more
		CTCF	Unknown	28481359	Open Targets	—
		CTNNB1	Unknown	24700283 28481359	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CUX1	Unknown	21252315	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
		CXCR4	Unknown	28481359	Open Targets	Viral life cycle - HIV-1 Virion - Human immunodeficiency virus Calcium signaling pathway +15 more
		DAXX	Unknown	32586046 29092957 27994516 21252315 28179320 28481359	Open Targets	MAPK signaling pathway Apoptosis Parkinson disease +6 more
		DDR2	Unknown	28481359	Open Targets	Non-integrin membrane-ECM interactions

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Pancreatic neuroendocrine tumor

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