Subtype of: Melanoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
nodular malignant melanoma	MONDO_0000930	EZH2	Unknown	36219477 26359337	Open Targets	Lysine degradation Metabolic pathways Polycomb repressive complex +7 more
		EZR	Unknown	36219477 26359337	Open Targets	Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton +6 more
		FAM131B	Unknown	33024263	Open Targets	Signaling by BRAF and RAF fusions
		FAM135B	Unknown	22197931 33024263 26359337 30178487	Open Targets	—
		FAM47C	Unknown	33024263 26359337 30178487	Open Targets	—
		FANCA	Unknown	33024263 36219477 30178487 26359337	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCD2	Unknown	22197931 36219477 30178487 26359337	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
		FANCE	Unknown	36219477	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCF	Unknown	36219477	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCG	Unknown	36219477 26359337	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FAS	Unknown	36219477	Open Targets	Platinum drug resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +36 more
		FAT1	Unknown	33024263 36219477 30178487 26359337	Open Targets	—
		FAT3	Unknown	33024263 26359337 30178487	Open Targets	—
		FAT4	Unknown	22197931 33024263 26359337 30178487	Open Targets	Hippo signaling pathway - multiple species
		FBLN2	Unknown	33024263	Open Targets	Cytoskeleton in muscle cells Molecules associated with elastic fibres
		FBXO11	Unknown	33024263 26359337	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXW7	Unknown	33024263 36219477 26359337	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		FCGR2B	Unknown	33024263	Open Targets	Virion - Ebolavirus, Lyssavirus and Morbillivirus Phagosome Osteoclast differentiation +6 more
		FCRL4	Unknown	33024263 26359337 36219477	Open Targets	—
		FES	Unknown	33024263	Open Targets	Axon guidance Signaling by SCF-KIT Sema3A PAK dependent Axon repulsion +1 more
		FGFR1	Unknown	26359337 30178487 36219477	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +32 more
		FGFR2	Unknown	22197931 33024263 26359337 36219477	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FGFR3	Unknown	26359337 30178487 28870692 36219477	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +27 more
		FGFR4	Unknown	36901951 36219477 30178487	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +20 more
		FHIT	Unknown	26359337	Open Targets	Purine metabolism Metabolic pathways Small cell lung cancer +1 more
		FKBP9	Unknown	33024263	Open Targets	—
		FLCN	Unknown	30178487	Open Targets	mTOR signaling pathway Renal cell carcinoma Amino acids regulate mTORC1
		FLNA	Unknown	33024263 26359337	Open Targets	MAPK signaling pathway Focal adhesion Salmonella infection +6 more
		FLT3	Unknown	33024263 36219477 26359337	Open Targets	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		FLT4	Unknown	33024263 26359337 30178487 22197931	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		FNBP1	Unknown	33024263	Open Targets	Shigellosis Clathrin-mediated endocytosis
		FOXA1	Unknown	33024263 36219477	Open Targets	Estrogen-dependent gene expression
		FOXL2	Unknown	36219477	Open Targets	SUMOylation of transcription factors
		FOXO3	Unknown	33024263 26359337	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway FoxO signaling pathway +26 more
		FOXO4	Unknown	33024263	Open Targets	Ras signaling pathway FoxO signaling pathway Shigellosis +7 more
		FOXP1	Unknown	33024263 36219477 26359337	Open Targets	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		FUBP1	Unknown	36219477	Open Targets	—
		FUS	Unknown	26359337	Open Targets	mRNA surveillance pathway Spliceosome Amyotrophic lateral sclerosis +3 more
		GATA1	Unknown	33024263	Open Targets	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Factors involved in megakaryocyte development and platelet production
		GATA3	Unknown	36219477	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation Parathyroid hormone synthesis, secretion and action +6 more
		GLI1	Unknown	33024263 26359337 30178487	Open Targets	cAMP signaling pathway Hedgehog signaling pathway Pathways in cancer +5 more
		GMPS	Unknown	33024263	Open Targets	Purine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		GNA11	Unknown	36219477 26825879	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway Hormone signaling +23 more
		GNAQ	Unknown	26359337 36219477	Open Targets	Rap1 signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +52 more
		GNAS	Unknown	33024263 26359337 36219477	Open Targets	Endocrine resistance Rap1 signaling pathway Calcium signaling pathway +58 more
		GOLPH3	Unknown	30178487	Open Targets	—
		GPC3	Unknown	33024263	Open Targets	Proteoglycans in cancer A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis +9 more
		GPC5	Unknown	26359337	Open Targets	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG degradation +7 more
		GPHN	Unknown	22197931 26359337	Open Targets	Folate biosynthesis Metabolic pathways Biosynthesis of cofactors +2 more
		GRIN2A	Unknown	33024263 36219477 30178487 22197931 26359337 28356599	Open Targets	Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway +19 more

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Nodular malignant melanoma

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