Subtype of: Melanoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
nodular malignant melanoma	MONDO_0000930	CD79B	Unknown	33024263	Open Targets	B cell receptor signaling pathway CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
		CDH1	Unknown	33024263 36219477	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		CDH10	Unknown	22197931 33024263 26359337 30178487	Open Targets	Adherens junctions interactions
		CDH11	Unknown	33024263 26359337 30178487	Open Targets	Adherens junctions interactions
		CDH17	Unknown	22197931 33024263 26359337 30178487	Open Targets	Gastric cancer Adherens junctions interactions
		CDK12	Unknown	33024263 36219477 26359337	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDK4	Unknown	36219477	Open Targets	Endocrine resistance Cell cycle p53 signaling pathway +40 more
		CDK6	Unknown	36219477	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +27 more
		CDKN1A	Unknown	33024263 36219477 26359337	Open Targets	Endocrine resistance Platinum drug resistance ErbB signaling pathway +56 more
		CDKN1B	Unknown	36901951 26359337 36219477	Open Targets	Endocrine resistance ErbB signaling pathway HIF-1 signaling pathway +28 more
		CDKN2A	Unknown	20460471 22493355 25407517 33024263 20703244 36219477 8562340 30178487 20544847 36901951 15195137 19158841 9536218 10229204 9617435 8751963	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CDKN2C	Unknown	36219477	Open Targets	Endocrine resistance Cell cycle Cushing syndrome +6 more
		CDX2	Unknown	36219477 26359337	Open Targets	Gastric cancer Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
		CEP43	Unknown	33024263 26359337	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		CEP89	Unknown	26359337 30178487	Open Targets	Anchoring of the basal body to the plasma membrane
		CHD2	Unknown	22197931 33024263 30178487	Open Targets	—
		CHEK2	Unknown	33024263 36219477 26359337	Open Targets	Cell cycle p53 signaling pathway Cellular senescence +9 more
		CHST11	Unknown	33024263 26359337	Open Targets	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate Chondroitin sulfate biosynthesis
		CIC	Unknown	33024263 36219477 26359337	Open Targets	Spinocerebellar ataxia
		CIITA	Unknown	33024263 26359337 30178487	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CLIP1	Unknown	33024263 26359337	Open Targets	mTOR signaling pathway Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids +5 more
		CLTC	Unknown	26359337 30178487	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		CLTCL1	Unknown	33024263 30178487	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +8 more
		CNBD1	Unknown	33024263 26359337 30178487	Open Targets	—
		CNBP	Unknown	33024263	Open Targets	—
		CNOT3	Unknown	26359337 36219477	Open Targets	RNA degradation Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		CNTNAP2	Unknown	33024263 26359337 30178487 36219477	Open Targets	Cell adhesion molecules
		CNTRL	Unknown	33024263	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		COL1A1	Unknown	33024263 36219477 30178487 26359337	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL2A1	Unknown	22197931 33024263 36219477 30178487 26359337	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		COL3A1	Unknown	33024263 26359337 30178487 22197931	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CPEB3	Unknown	33024263	Open Targets	Oocyte meiosis Progesterone-mediated oocyte maturation
		CREB1	Unknown	33024263 36219477 26359337	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway Efferocytosis +53 more
		CREB3L1	Unknown	33024263	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway PI3K-Akt signaling pathway +32 more
		CREB3L2	Unknown	33024263	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway PI3K-Akt signaling pathway +32 more
		CREBBP	Unknown	33024263 36219477	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRLF2	Unknown	36219477 26359337	Open Targets	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Interleukin-7 signaling
		CRNKL1	Unknown	33024263	Open Targets	Spliceosome mRNA Splicing - Major Pathway
		CRTC1	Unknown	33024263 26359337 30178487	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CRTC3	Unknown	33024263 36219477 30178487	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CSF1R	Unknown	33024263 26359337	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CSF3R	Unknown	22197931 33024263 36219477 26359337	Open Targets	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway JAK-STAT signaling pathway +3 more
		CSMD3	Unknown	33024263 26359337 30178487 36219477	Open Targets	—
		CTCF	Unknown	33024263 26359337 36219477	Open Targets	—
		CTNNA1	Unknown	33024263	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +9 more
		CTNNA2	Unknown	33024263 26359337 30178487	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		CTNNB1	Unknown	33024263 36219477 12124804 27175588 26359337	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CTNND1	Unknown	26359337	Open Targets	Rap1 signaling pathway Adherens junction Leukocyte transendothelial migration +3 more
		CTNND2	Unknown	33024263 26359337 30178487 22197931	Open Targets	Wnt signaling pathway
		CUL3	Unknown	33024263	Open Targets	Ubiquitin mediated proteolysis Hedgehog signaling pathway Degradation of DVL +4 more

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Nodular malignant melanoma

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