Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
MYOCARDIAL INFARCTION	C0027051 MESH:D009203 EFO_0000612	PLAT	Unknown	10171637 10505926 10645301 10914357 11382373 11489769 12074692 12227717 12848087 1430592 1492007 15215796 15301905 18195371 1898952 1899364 1900011 19341228 20122609 2104561 2105625 2494454 2505604 2521976 3089627 3121335 7488445	CTD, Disgenet	Apelin signaling pathway Complement and coagulation cascades Transcriptional misregulation in cancer +4 more
		PLAU	Unknown	1908371 2174952 2382605 3068399 3984876 8416330	CTD, Disgenet	NF-kappa B signaling pathway Complement and coagulation cascades Transcriptional misregulation in cancer +5 more
		PLCB2	Unknown	30226566	GWAS catalog	Inositol phosphate metabolism Metabolic pathways Rap1 signaling pathway +67 more
		PLCG1	Unknown	38072966	GWAS catalog	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +70 more
		PLCG2	Unknown	33532862 38072966	GWAS catalog	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +49 more
		PLCL2	Unknown	24916648	GWAS catalog	—
		PLEKHG1	Unknown	33532862 38072966	GWAS catalog	—
		PLG	Unknown	26343387 37947095 38072966	GWAS catalog	Neuroactive ligand-receptor interaction Complement and coagulation cascades Staphylococcus aureus infection +7 more
		PLN	Unknown	16026515 16162791	CTD, Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +6 more
		PLPP3	Unknown	26343387 33532862 38072966	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism +7 more
		PLPPR2	Unknown	38072966	GWAS catalog	Lysosphingolipid and LPA receptors
		PLXNB1	Unknown	38072966	GWAS catalog	Axon guidance G alpha (12/13) signalling events Sema4D mediated inhibition of cell attachment and migration +1 more
		PMFBP1	Unknown	38072966	GWAS catalog	—
		PNLDC1	Unknown	38072966	GWAS catalog	RNA degradation
		POC1B	Unknown	38072966	GWAS catalog	—
		PON1	Unknown	—	Disgenet	Synthesis of 5-eicosatetraenoic acids
		PPARA	Unknown	—	Disgenet	PPAR signaling pathway cAMP signaling pathway Adipocytokine signaling pathway +16 more
		PPARGC1A	Unknown	22503866	CTD, Disgenet	AMPK signaling pathway Longevity regulating pathway Apelin signaling pathway +12 more
		PPP2R3A	Unknown	33532862	GWAS catalog	mRNA surveillance pathway Sphingolipid signaling pathway PI3K-Akt signaling pathway +5 more
		PRDM16	Unknown	34594039	GWAS catalog	Lysine degradation Metabolic pathways Thermogenesis +1 more
		PRDM8	Unknown	33532862 34594039 38072966	GWAS catalog	—
		PREX1	Unknown	38072966	GWAS catalog	Chemokine signaling pathway Kaposi sarcoma-associated herpesvirus infection NRAGE signals death through JNK +2 more
		PRIM2	Unknown	33532862 38072966	GWAS catalog	DNA replication Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere +6 more
		PRKCE	Unknown	16782078	CTD, Disgenet	cGMP-PKG signaling pathway Sphingolipid signaling pathway Vascular smooth muscle contraction +14 more
		PRKCH	Unknown	38072966	GWAS catalog	Vascular smooth muscle contraction Inflammatory mediator regulation of TRP channels Effects of PIP2 hydrolysis
		PROCR	Unknown	33532862 38072966 39024449	GWAS catalog	Complement and coagulation cascades Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
		PSMA6	Unknown	16845397	CTD, Disgenet	Proteasome Alzheimer disease Parkinson disease +56 more
		PSMB4	Unknown	38072966	GWAS catalog	Proteasome Alzheimer disease Parkinson disease +56 more
		PSRC1	Unknown	19198609 39024449	GWAS catalog	—
		PTGIS	Unknown	—	Disgenet	Arachidonic acid metabolism Metabolic pathways Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol +6 more
		PTGS2	Unknown	—	Disgenet	Arachidonic acid metabolism Metabolic pathways NF-kappa B signaling pathway +29 more
		PTPN11	Unknown	38072966	GWAS catalog	Ras signaling pathway Phospholipase D signaling pathway Efferocytosis +56 more
		PTPRJ	Unknown	38072966	GWAS catalog	Adherens junction Chemical carcinogenesis - reactive oxygen species Phosphorylation of CD3 and TCR zeta chains +2 more
		QKI	Unknown	26950853	GWAS catalog	Signaling by BRAF and RAF fusions
		R3HCC1L	Unknown	38072966	GWAS catalog	—
		RAB23	Unknown	33532862 38072966	GWAS catalog	RAB geranylgeranylation
		RAI1	Unknown	38072966	GWAS catalog	—
		RAPH1	Unknown	38072966	GWAS catalog	—
		RASGEF1B	Unknown	33532862 34594039 38072966	GWAS catalog	—
		RBM33	Unknown	38072966	GWAS catalog	—
		REN	Unknown	1668233	CTD, Disgenet	Renin-angiotensin system Renin secretion Diabetic cardiomyopathy +1 more
		REST	Unknown	33532862 34594039 38072966	GWAS catalog	Signaling pathways regulating pluripotency of stem cells Huntington disease HDACs deacetylate histones +1 more
		RFXAP	Unknown	25948407	GWAS catalog	Antigen processing and presentation Tuberculosis Primary immunodeficiency
		RGS12	Unknown	38072966	GWAS catalog	G alpha (i) signalling events
		RHOA	Unknown	38072966	GWAS catalog	Ras signaling pathway Rap1 signaling pathway cGMP-PKG signaling pathway +64 more
		RIC8A	Unknown	38072966	GWAS catalog	—
		RNF123	Unknown	38072966	GWAS catalog	Ub-specific processing proteases Antigen processing: Ubiquitination & Proteasome degradation
		RNF13	Unknown	26708285	GWAS catalog	—
		RPP25	Unknown	33532862	GWAS catalog	Ribosome biogenesis in eukaryotes tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
		RSPH6A	Unknown	33532862 38072966	GWAS catalog	—
MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO	MONDO:0012039	PSMA6	Unknown	—	ClinVar	Proteasome Alzheimer disease Parkinson disease +56 more

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