Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	XBP1	Unknown	30661753	CTD, Disgenet	Protein processing in endoplasmic reticulum Non-alcoholic fatty liver disease Alzheimer disease +8 more
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	YWHAG	Unknown	21654844	GWAS catalog	Cell cycle Oocyte meiosis PI3K-Akt signaling pathway +15 more
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZBTB38	Unknown	24076602 31604244	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZBTB46	Unknown	21833088 31407831	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZC2HC1A	Unknown	24076602 38616254 40262193	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZC3HAV1	Unknown	31604244	GWAS catalog	Herpes simplex virus 1 infection Signaling by BRAF and RAF fusions
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZFHX3	Unknown	19010793	GWAS catalog	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZFP36L1	Unknown	21833088 24076602 31604244 40262193	GWAS catalog	Cellular senescence Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZHX3	Unknown	31604244	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZMIZ1	Unknown	19525953 21833088 22190364 24076602 31407831 31604244 40262193	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZNF267	Unknown	31068361	CTD, Disgenet	Generic Transcription Pathway
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZNF433	Unknown	20598377	GWAS catalog	Generic Transcription Pathway
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZNF438	Unknown	31604244	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZNF627	Unknown	19010793	GWAS catalog	Generic Transcription Pathway
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZNF652	Unknown	31604244	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZNHIT3	Unknown	31604244	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZPLD1	Unknown	21833088 26920376 31604244	GWAS catalog	—
MULTIPLE SCLEROSIS	C0026769 MESH:D009103 MONDO_0005301	ZSCAN23	Unknown	37377963	GWAS catalog	—
MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE	C0393665	HNRNPA1	Unknown	—	Disgenet	Spliceosome Amyotrophic lateral sclerosis FGFR2 alternative splicing +2 more
MULTIPLE SCLEROSIS, RELAPSING-REMITTING	C0751967 MESH:D020529	ACKR3	Unknown	34624384	CTD, Disgenet	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine receptors bind chemokines +1 more
MULTIPLE SCLEROSIS, RELAPSING-REMITTING	C0751967 MESH:D020529	ADAMTS14	Unknown	—	Disgenet	Collagen biosynthesis and modifying enzymes Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
MULTIPLE SCLEROSIS, RELAPSING-REMITTING	C0751967 MESH:D020529	CSPG4	Unknown	—	Disgenet	A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis +7 more
MULTIPLE SCLEROSIS, RELAPSING-REMITTING	C0751967 MESH:D020529	HNRNPA1	Unknown	—	Disgenet	Spliceosome Amyotrophic lateral sclerosis FGFR2 alternative splicing +2 more
MULTIPLE SCLEROSIS, RELAPSING-REMITTING	C0751967 MESH:D020529	KLC1	Unknown	—	Disgenet	Motor proteins Alzheimer disease Parkinson disease +9 more
MULTIPLE SCLEROSIS, RELAPSING-REMITTING	C0751967 MESH:D020529	NOD2	Unknown	—	Disgenet	NOD-like receptor signaling pathway TNF signaling pathway Tuberculosis +7 more
MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO, 5	MONDO:0013893	TNFRSF1A	Unknown	—	ClinVar	MAPK signaling pathway Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor +39 more

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Multiple sclerosis

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