Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
LUNG NEOPLASMS	MESH:D008175	CHRNA5	Unknown	18385738	CTD	Neuroactive ligand-receptor interaction Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
		CHRNA7	Unknown	24089524	CTD	Calcium signaling pathway Neuroactive ligand-receptor interaction Cholinergic synapse +5 more
		CHRNB4	Unknown	18385738	CTD	Neuroactive ligand-receptor interaction Cholinergic synapse Chemical carcinogenesis - receptor activation +4 more
		CHST15	Unknown	27935865	CTD	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate Chondroitin sulfate biosynthesis
		CLCA2	Unknown	27935865	CTD	Renin secretion Pancreatic secretion Stimuli-sensing channels
		CLPTM1L	Unknown	18978787 19151717 23433592 24366883	CTD	—
		CLTB	Unknown	27935865	CTD	Lysosome Endocytosis Synaptic vesicle cycle +11 more
		COL6A1	Unknown	23692979	CTD	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +11 more
		COX17	Unknown	23624903	CTD	Oxidative phosphorylation Metabolic pathways Thermogenesis
		CPE	Unknown	27935865	CTD	Type I diabetes mellitus
		CRP	Unknown	17114654	CTD	Classical antibody-mediated complement activation
		CTNNB1	Unknown	18372914	CTD	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CWH43	Unknown	27935865	CTD	—
		CXCL14	Unknown	20562917	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway
		CYP1A2	Unknown	22072123	CTD	Steroid hormone biosynthesis Caffeine metabolism Tryptophan metabolism +15 more
		CYP1B1	Unknown	11376689	CTD	Steroid hormone biosynthesis Tryptophan metabolism Metabolism of xenobiotics by cytochrome P450 +9 more
		CYP24A1	Unknown	22797725	CTD	Steroid biosynthesis Metabolic pathways Parathyroid hormone synthesis, secretion and action +4 more
		CYP2A6	Unknown	10441482 11241319 12214673 16176798 17549345 26132489	CTD	Caffeine metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 +7 more
		CYP2E1	Unknown	1673675 17093202	CTD	Steroid hormone biosynthesis Arachidonic acid metabolism Linoleic acid metabolism +11 more
		DAB2IP	Unknown	22046421	CTD	Apoptosis TNF signaling pathway Regulation of RAS by GAPs
		DAPK1	Unknown	15172992	CTD	Autophagy - animal Pathways in cancer Bladder cancer
		DDR1	Unknown	21552421	CTD	Non-integrin membrane-ECM interactions
		DNAI7	Unknown	15064703	CTD	—
		DNASE1L3	Unknown	21720004	CTD	—
		DNMT3A	Unknown	26192916	CTD	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		DOK1	Unknown	20139980	CTD	PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 RET signaling
		DOK2	Unknown	20139980	CTD	Tie2 Signaling RET signaling
		DOK3	Unknown	20139980	CTD	Neutrophil degranulation
		DPYD	Unknown	19020767	CTD	Pyrimidine metabolism beta-Alanine metabolism Pantothenate and CoA biosynthesis +3 more
		EAF2	Unknown	20564326	CTD	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
		EEF2	Unknown	21554491	CTD	AMPK signaling pathway Oxytocin signaling pathway Peptide chain elongation +4 more
		EFEMP1	Unknown	17671114	CTD	Molecules associated with elastic fibres
		EFNB2	Unknown	27935865	CTD	Axon guidance EPH-Ephrin signaling EPHB-mediated forward signaling +2 more
		EGFR	Unknown	18927287 19336973 20934974 21541241 23523951 27935865 29106415	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		EGR1	Unknown	27935865	CTD	Apelin signaling pathway GnRH signaling pathway Parathyroid hormone synthesis, secretion and action +6 more
		EHMT2	Unknown	20940408	CTD	Lysine degradation Metabolic pathways Longevity regulating pathway +6 more
		EMX2	Unknown	20697358	CTD	—
		EPHX1	Unknown	17114358 17311802	CTD	Metabolism of xenobiotics by cytochrome P450 Bile secretion Chemical carcinogenesis - DNA adducts +3 more
		ERBB2	Unknown	12483526	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		ERBB3	Unknown	12483526	CTD	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERCC1	Unknown	30453383	CTD	Platinum drug resistance Nucleotide excision repair Fanconi anemia pathway +5 more
		ERCC6	Unknown	17854076	CTD	Nucleotide excision repair B-WICH complex positively regulates rRNA expression Formation of TC-NER Pre-Incision Complex +4 more
		ERGIC3	Unknown	27588471	CTD	—
		ESR1	Unknown	11872642 17077188	CTD	Endocrine resistance Hormone signaling Estrogen signaling pathway +21 more
		FAS	Unknown	26192916	CTD	Platinum drug resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +36 more
		FASLG	Unknown	—	CTD	Platinum drug resistance MAPK signaling pathway Ras signaling pathway +38 more
		FEN1	Unknown	28371273	CTD	DNA replication Base excision repair Non-homologous end-joining +6 more
		FGF9	Unknown	20464547	CTD	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +46 more
		FGFR1	Unknown	21936542	CTD	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +32 more
		FGFR2	Unknown	17311802	CTD	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more

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Lung neoplasms

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