Subtype of: Gastric cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
gastric intestinal type adenocarcinoma	MONDO_0005037	NSD1	Unknown	24816253 29945994 33328548 25042771	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		NSD2	Unknown	24816253 33328548 25042771	Open Targets	Lysine degradation Metabolic pathways Transcriptional misregulation in cancer +5 more
		NSD3	Unknown	29945994 25042771	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		NT5C2	Unknown	29945994 24690483	Open Targets	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism +4 more
		NTRK1	Unknown	24816253 22484628 36232418 33328548 25042771 29945994	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +13 more
		NTRK2	Unknown	24816253 24807215	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +6 more
		NTRK3	Unknown	24816253 33328548 24807215 25042771	Open Targets	Calcium signaling pathway Neurotrophin signaling pathway Central carbon metabolism in cancer +4 more
		NUMA1	Unknown	24816253 29945994 33328548 25042771	Open Targets	Recruitment of NuMA to mitotic centrosomes Mitotic Prophase
		NUP214	Unknown	24816253 29945994 33328548 24807215 25042771	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis ISG15 antiviral mechanism +26 more
		NUP98	Unknown	24816253 33328548 24807215	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis Influenza A +33 more
		NUTM1	Unknown	24816253 29945994	Open Targets	—
		OLIG2	Unknown	24816253 29945994	Open Targets	—
		OMD	Unknown	24816253	Open Targets	Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 +2 more
		P2RY8	Unknown	24816253	Open Targets	Neuroactive ligand-receptor interaction
		PABPC1	Unknown	24816253	Open Targets	mRNA surveillance pathway RNA degradation L13a-mediated translational silencing of Ceruloplasmin expression +5 more
		PAFAH1B2	Unknown	24816253	Open Targets	Ether lipid metabolism Metabolic pathways Neutrophil degranulation +1 more
		PALB2	Unknown	24816253 33328548 25042771	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Homologous Recombination (HRR) +3 more
		PATZ1	Unknown	24816253 29945994	Open Targets	—
		PAX3	Unknown	24816253 29945994 33328548	Open Targets	Transcriptional misregulation in cancer HATs acetylate histones
		PAX5	Unknown	29945994 33328548 25042771	Open Targets	Transcriptional misregulation in cancer RUNX1 regulates transcription of genes involved in BCR signaling
		PAX7	Unknown	24816253 33328548 24807215	Open Targets	Transcriptional misregulation in cancer
		PAX8	Unknown	29945994 33328548 25042771	Open Targets	Thyroid hormone synthesis Pathways in cancer Transcriptional misregulation in cancer +1 more
		PBRM1	Unknown	24816253 29945994 33328548 25042771	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		PBX1	Unknown	33328548	Open Targets	Efferocytosis Cortisol synthesis and secretion Cushing syndrome +3 more
		PCM1	Unknown	24816253 25042771	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +4 more
		PDCD1LG2	Unknown	24816253	Open Targets	Cell adhesion molecules PD-1 signaling
		PDE4DIP	Unknown	24816253 29945994 25042771	Open Targets	—
		PDGFB	Unknown	24816253	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +25 more
		PDGFRA	Unknown	24816253 36232418 33328548 25042771 29945994 31620276	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +30 more
		PDGFRB	Unknown	24816253 22484628 29945994 33328548	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +22 more
		PER1	Unknown	24816253 29945994 36232418 33328548 25042771	Open Targets	Circadian rhythm Circadian entrainment
		PHF6	Unknown	24816253	Open Targets	ATP-dependent chromatin remodeling
		PHOX2B	Unknown	36232418 33328548	Open Targets	—
		PICALM	Unknown	25042771	Open Targets	Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
		PIK3CA	Unknown	24816253 22484628 24807215 19962665 23196062 25656989 36232418 33328548 25042771 29945994 15784156 31620276 25127237	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		PIK3CB	Unknown	24816253 33328548 36232418 24807215 25042771	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +126 more
		PIK3R1	Unknown	24816253 33431761 36232418 33328548	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +150 more
		PIK3R2	Unknown	24816253 33328548 25042771	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +129 more
		PIK3R3	Unknown	24816253 29945994 25042771	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +116 more
		PIM1	Unknown	33328548	Open Targets	JAK-STAT signaling pathway AGE-RAGE signaling pathway in diabetic complications Pathways in cancer +3 more
		PLAG1	Unknown	24816253	Open Targets	—
		PLCG1	Unknown	24816253 36232418 33328548 25042771	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +70 more
		PLEC	Unknown	24816253 29945994 25042771	Open Targets	Cytoskeleton in muscle cells Assembly of collagen fibrils and other multimeric structures Caspase-mediated cleavage of cytoskeletal proteins +1 more
		PML	Unknown	24816253 29945994 33328548 25042771	Open Targets	Ubiquitin mediated proteolysis Endocytosis Influenza A +12 more
		PMS1	Unknown	24816253 29945994 36232418 25042771	Open Targets	—
		PMS2	Unknown	24816253 29945994 36232418	Open Targets	Mismatch repair Fanconi anemia pathway Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) +3 more
		POLD1	Unknown	24816253 29945994 36232418	Open Targets	DNA replication Base excision repair Nucleotide excision repair +19 more
		POLE	Unknown	24816253 29945994 25042771	Open Targets	DNA replication Base excision repair Nucleotide excision repair +10 more
		POLG	Unknown	24816253 29945994 25042771	Open Targets	Base excision repair
		POLQ	Unknown	24816253 29945994 25042771	Open Targets	HDR through MMEJ (alt-NHEJ)

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Gastric intestinal type adenocarcinoma

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