Subtype of: Gastric cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
gastric intestinal type adenocarcinoma	MONDO_0005037	KLK2	Unknown	25042771	Open Targets	Renin-angiotensin system Endocrine and other factor-regulated calcium reabsorption Activation of Matrix Metalloproteinases +2 more
		KMT2A	Unknown	24816253 22484628 29945994 33328548 25042771	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KMT2C	Unknown	24816253 22484628 36232418 33328548 25042771 29945994	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		KMT2D	Unknown	24816253 38584451 24807215 30474112 36232418 33328548 25042771 29945994	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KNL1	Unknown	24807215 33328548	Open Targets	Cell cycle Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids +5 more
		KNSTRN	Unknown	29945994	Open Targets	—
		KRAS	Unknown	24816253 11807778 19962665 7903667 23196062 12163385 2049776 15616773 25656989 24807215 36232418 14534542 22361929 23511561 7780983 31620276 14618633 29945994 14513361 12204060 25127237	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		KTN1	Unknown	24816253 29945994	Open Targets	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RHO GTPases activate KTN1 Post-translational protein phosphorylation
		LARP4B	Unknown	24816253 29945994 25042771	Open Targets	—
		LASP1	Unknown	25042771	Open Targets	—
		LATS1	Unknown	24816253	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LATS2	Unknown	24816253	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LCK	Unknown	29945994 33328548 24807215	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Natural killer cell mediated cytotoxicity +27 more
		LEF1	Unknown	22484628	Open Targets	Wnt signaling pathway Hippo signaling pathway Adherens junction +24 more
		LHFPL6	Unknown	24816253	Open Targets	—
		LIFR	Unknown	24816253 33328548	Open Targets	Cytokine-cytokine receptor interaction Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway +2 more
		LMNA	Unknown	24816253 25042771	Open Targets	Apoptosis Cytoskeleton in muscle cells Hypertrophic cardiomyopathy +8 more
		LMO1	Unknown	24816253	Open Targets	RUNX1 regulates transcription of genes involved in differentiation of HSCs
		LMO2	Unknown	29945994	Open Targets	Transcriptional misregulation in cancer RUNX1 regulates transcription of genes involved in differentiation of HSCs
		LOC100506403	Unknown	29945994 33328548	Open Targets	—
		LOC105376156	Unknown	33328548 25042771	Open Targets	—
		LOC124905021	Unknown	24816253 17367471	Open Targets	—
		LPP	Unknown	29945994 33328548 25042771	Open Targets	—
		LRIG3	Unknown	24816253 29945994 25042771	Open Targets	—
		LRP1B	Unknown	24816253 22484628 24807215 36232418 33328548 25042771 29945994	Open Targets	—
		LSM14A	Unknown	29945994	Open Targets	—
		LZTR1	Unknown	24816253	Open Targets	—
		MACC1	Unknown	24816253 29945994 25042771	Open Targets	—
		MAF	Unknown	29945994 33328548	Open Targets	Th1 and Th2 cell differentiation Transcriptional misregulation in cancer Inflammatory bowel disease
		MALT1	Unknown	24816253 33328548 25042771	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		MAML2	Unknown	24816253 33328548 24807215 25042771	Open Targets	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MAP2K1	Unknown	24816253 33328548	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MAP2K2	Unknown	33328548 25042771	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +87 more
		MAP2K4	Unknown	33328548	Open Targets	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway +21 more
		MAP3K1	Unknown	24816253 29945994 36232418	Open Targets	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K13	Unknown	36232418 25042771	Open Targets	MAPK signaling pathway
		MAPK1	Unknown	24816253	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +161 more
		MAX	Unknown	24816253 25042771	Open Targets	Polycomb repressive complex MAPK signaling pathway Pathways in cancer +6 more
		MB21D2	Unknown	24816253 29945994	Open Targets	—
		MDM4	Unknown	33328548	Open Targets	p53 signaling pathway MicroRNAs in cancer Oxidative Stress Induced Senescence +6 more
		MECOM	Unknown	22484628 25042771	Open Targets	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MED12	Unknown	24816253 29945994 36232418 25042771	Open Targets	Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway +1 more
		MEN1	Unknown	33328548 25042771	Open Targets	Cushing syndrome Transcriptional misregulation in cancer Formation of the beta-catenin:TCF transactivating complex +5 more
		MET	Unknown	24816253 33328548	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		MGMT	Unknown	36232418	Open Targets	MGMT-mediated DNA damage reversal
		MITF	Unknown	33328548	Open Targets	Mitophagy - animal Osteoclast differentiation Melanogenesis +4 more
		MLF1	Unknown	24816253 29945994	Open Targets	Transcriptional misregulation in cancer
		MLH1	Unknown	24816253 29945994 23196062 25042771	Open Targets	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MLLT10	Unknown	33328548 25042771	Open Targets	—
		MLLT3	Unknown	24816253 25042771	Open Targets	Viral life cycle - HIV-1 Transcriptional misregulation in cancer Formation of RNA Pol II elongation complex +2 more

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Gastric intestinal type adenocarcinoma

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