Gastric adenoma

N-Glycan biosynthesis Various types of N-glycan biosynthesis Metabolic pathways Protein processing in endoplasmic reticulum Asparagine N-linked glycosylation +2 more

MAPK signaling pathway Ras signaling pathway cAMP signaling pathway Phospholipase D signaling pathway Mitophagy - animal Autophagy - animal Cellular senescence Apelin signaling pathway C-type lectin receptor signaling pathway Regulation of actin cytoskeleton Proteoglycans in cancer +8 more

Wnt signaling pathway Regulation of FZD by ubiquitination RUNX1 regulates transcription of genes involved in WNT signaling

Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia

POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells Regulation of PTEN gene transcription

Parkinson disease Pathways of neurodegeneration - multiple diseases

Lysine degradation Metabolic pathways PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function +1 more

Lysine degradation Metabolic pathways PKMTs methylate histone lysines

Lysine degradation Metabolic pathways Signaling pathways regulating pluripotency of stem cells PKMTs methylate histone lysines +1 more

PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis

FoxO signaling pathway Efferocytosis mTOR signaling pathway PI3K-Akt signaling pathway Parathyroid hormone synthesis, secretion and action Aldosterone-regulated sodium reabsorption Stimuli-sensing channels Regulation of TP53 Degradation NGF-stimulated transcription +6 more

Neurotrophin signaling pathway Regulation of KIT signaling Factors involved in megakaryocyte development and platelet production

Endocytosis EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis +2 more

Parathyroid hormone synthesis, secretion and action Mineral absorption Type II Na+/Pi cotransporters Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) Surfactant metabolism +2 more

FoxO signaling pathway Hormone signaling Cell cycle Wnt signaling pathway TGF-beta signaling pathway Apelin signaling pathway Hippo signaling pathway Adherens junction Signaling pathways regulating pluripotency of stem cells Th17 cell differentiation AGE-RAGE signaling pathway in diabetic complications Hepatitis B Human T-cell leukemia virus 1 infection Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia Hepatocellular carcinoma Gastric cancer Signaling by NODAL Signaling by Activin Signaling by BMP TGF-beta receptor signaling activates SMADs Downregulation of SMAD2/3:SMAD4 transcriptional activity SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription SMAD4 MH2 Domain Mutants in Cancer SMAD2/3 MH2 Domain Mutants in Cancer Transcriptional regulation of pluripotent stem cells Ub-specific processing proteases RUNX2 regulates bone development RUNX3 regulates CDKN1A transcription RUNX3 regulates BCL2L11 (BIM) transcription FOXO-mediated transcription of cell cycle genes +30 more

ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma Interleukin-7 signaling Formation of the beta-catenin:TCF transactivating complex RMTs methylate histone arginines Chromatin modifying enzymes RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known EGR2 and SOX10-mediated initiation of Schwann cell myelination +6 more

ATP-dependent chromatin remodeling Viral life cycle - HIV-1 Thermogenesis Hepatocellular carcinoma RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known +3 more

ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known +2 more

Viral carcinogenesis Signaling by BRAF and RAF fusions

Notch signaling pathway

Hedgehog signaling pathway Hedgehog 'on' state

EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway Rap1 signaling pathway Chemokine signaling pathway Hormone signaling Mitophagy - animal Endocytosis Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Tight junction Gap junction Platelet activation Neutrophil extracellular trap formation C-type lectin receptor signaling pathway GABAergic synapse Inflammatory mediator regulation of TRP channels Regulation of actin cytoskeleton GnRH signaling pathway Estrogen signaling pathway Prolactin signaling pathway Thyroid hormone signaling pathway Oxytocin signaling pathway Relaxin signaling pathway Bacterial invasion of epithelial cells Epithelial cell signaling in Helicobacter pylori infection Pathogenic Escherichia coli infection Shigellosis Yersinia infection Tuberculosis Hepatitis B Human cytomegalovirus infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Viral carcinogenesis Proteoglycans in cancer Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Bladder cancer Lipid and atherosclerosis Fluid shear stress and atherosclerosis Signaling by ERBB2 Nuclear signaling by ERBB4 Downregulation of ERBB4 signaling PIP3 activates AKT signaling Spry regulation of FGF signaling Signaling by SCF-KIT Regulation of KIT signaling Signaling by EGFR GAB1 signalosome Downstream signal transduction Regulation of gap junction activity FCGR activation PECAM1 interactions Constitutive Signaling by Aberrant PI3K in Cancer Integrin signaling GRB2:SOS provides linkage to MAPK signaling for Integrins p130Cas linkage to MAPK signaling for integrins CD28 co-stimulation CTLA4 inhibitory signaling EPHB-mediated forward signaling EPHA-mediated growth cone collapse Ephrin signaling EPH-ephrin mediated repulsion of cells G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events DCC mediated attractive signaling GP1b-IX-V activation signalling Recycling pathway of L1 VEGFA-VEGFR2 Pathway Thrombin signalling through proteinase activated receptors (PARs) VEGFR2 mediated cell proliferation CLEC7A (Dectin-1) signaling RHO GTPases Activate Formins RAF activation MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Cyclin D associated events in G1 RET signaling MET activates PTK2 signaling InlA-mediated entry of Listeria monocytogenes into host cells Receptor Mediated Mitophagy Regulation of RUNX3 expression and activity Extra-nuclear estrogen signaling Activated NTRK3 signals through PI3K Signaling downstream of RAS mutants FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis +92 more

Axon guidance Rho GTPase cycle

Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression +4 more

EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway FoxO signaling pathway Hormone signaling Necroptosis Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway Th17 cell differentiation Prolactin signaling pathway Adipocytokine signaling pathway Insulin resistance AGE-RAGE signaling pathway in diabetic complications Growth hormone synthesis, secretion and action Toxoplasmosis Hepatitis C Hepatitis B Measles Human cytomegalovirus infection Kaposi sarcoma-associated herpesvirus infection Epstein-Barr virus infection Coronavirus disease - COVID-19 Pathways in cancer Viral carcinogenesis Proteoglycans in cancer MicroRNAs in cancer Chemical carcinogenesis - receptor activation Pancreatic cancer Acute myeloid leukemia Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer Inflammatory bowel disease Lipid and atherosclerosis Interleukin-6 signaling BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Interleukin-7 signaling Signaling by SCF-KIT Signaling by cytosolic FGFR1 fusion mutants Downstream signal transduction Senescence-Associated Secretory Phenotype (SASP) POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling PTK6 Activates STAT3 Interleukin-20 family signaling MET activates STAT3 Interleukin-15 signaling Interleukin-35 Signalling Interleukin-9 signaling Interleukin-37 signaling Interleukin-23 signaling Interleukin-27 signaling Interleukin-21 signaling Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Signaling by PDGFRA extracellular domain mutants +53 more

ErbB signaling pathway Chemokine signaling pathway Hormone signaling Necroptosis JAK-STAT signaling pathway Th1 and Th2 cell differentiation Th17 cell differentiation Prolactin signaling pathway AGE-RAGE signaling pathway in diabetic complications Growth hormone synthesis, secretion and action Hepatitis B Measles Human T-cell leukemia virus 1 infection Pathways in cancer Viral carcinogenesis Chemical carcinogenesis - receptor activation Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer Interleukin-7 signaling Signaling by SCF-KIT Signaling by cytosolic FGFR1 fusion mutants Downstream signal transduction Signaling by Leptin Interleukin-3, Interleukin-5 and GM-CSF signaling Interleukin-20 family signaling Interleukin-15 signaling Interleukin-9 signaling Interleukin-2 signaling Interleukin-21 signaling Growth hormone receptor signaling +28 more

FoxO signaling pathway Hormone signaling Autophagy - animal mTOR signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Longevity regulating pathway Tight junction Adipocytokine signaling pathway Energy dependent regulation of mTOR by LKB1-AMPK Regulation of TP53 Activity through Phosphorylation FOXO-mediated transcription of cell death genes +9 more

NF-kappa B signaling pathway Phospholipase D signaling pathway PI3K-Akt signaling pathway Osteoclast differentiation Platelet activation Neutrophil extracellular trap formation C-type lectin receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Tuberculosis Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Coronavirus disease - COVID-19 Viral carcinogenesis GPVI-mediated activation cascade FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis DAP12 signaling Fc epsilon receptor (FCERI) signaling Role of LAT2/NTAL/LAB on calcium mobilization FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization Integrin signaling Dectin-2 family Interleukin-2 signaling Regulation of signaling by CBL FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers +30 more

RUNX1 regulates transcription of genes involved in differentiation of HSCs

Wnt signaling pathway RORA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants HDACs deacetylate histones Notch-HLH transcription pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux HCMV Early Events +11 more

Signaling pathways regulating pluripotency of stem cells

Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation +5 more

Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs NGF-stimulated transcription

Signaling pathways regulating pluripotency of stem cells Human T-cell leukemia virus 1 infection Transcriptional misregulation in cancer Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs +2 more

Wnt signaling pathway Hippo signaling pathway Adherens junction Melanogenesis Cushing syndrome Alcoholic liver disease Salmonella infection Human papillomavirus infection Kaposi sarcoma-associated herpesvirus infection Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Breast cancer Hepatocellular carcinoma Gastric cancer Arrhythmogenic right ventricular cardiomyopathy Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Ca2+ pathway Binding of TCF/LEF:CTNNB1 to target gene promoters Repression of WNT target genes TCF7L2 mutants don't bind CTBP Transcriptional Regulation by VENTX RUNX3 regulates WNT signaling +26 more

Osteoclast differentiation T cell receptor signaling pathway Signaling by SCF-KIT FCERI mediated Ca+2 mobilization Interleukin-3, Interleukin-5 and GM-CSF signaling +2 more

Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer Hepatocellular carcinoma Gastric cancer Telomere Extension By Telomerase Formation of the beta-catenin:TCF transactivating complex +4 more

Pathways in cancer Thyroid cancer COPII-mediated vesicle transport

ATP-dependent chromatin remodeling UCH proteinases DNA Damage Recognition in GG-NER

Virion - Lassa virus and SFTS virus HIF-1 signaling pathway Endocytosis Phagosome Ferroptosis TGF-beta signaling pathway Hematopoietic cell lineage Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Transferrin endocytosis and recycling +8 more

MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway Endocytosis Cellular senescence TGF-beta signaling pathway Osteoclast differentiation Hippo signaling pathway Adherens junction Th17 cell differentiation Relaxin signaling pathway AGE-RAGE signaling pathway in diabetic complications Chagas disease Hepatitis B Human T-cell leukemia virus 1 infection Pathways in cancer Transcriptional misregulation in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia Hepatocellular carcinoma Gastric cancer Diabetic cardiomyopathy Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling activates SMADs TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) SMAD2/3 Phosphorylation Motif Mutants in Cancer TGFBR2 MSI Frameshift Mutants in Cancer TGFBR2 Kinase Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer +28 more

PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation

PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction Human papillomavirus infection MicroRNAs in cancer Integrin cell surface interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation +6 more