Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
female breast carcinoma	MONDO_0004379	PREX2	Unknown	22722201 27535334 28027327 29349598 38970069	Open Targets	Regulation of PTEN stability and activity
		PRKAR1A	Unknown	28027327 28481359 30062102 30205045 8545102	Open Targets	Insulin signaling pathway PKA activation PKA activation in glucagon signalling +7 more
		PTK6	Unknown	28027327	Open Targets	SCF(Skp2)-mediated degradation of p27/p21 Cyclin D associated events in G1 ERBB2 Activates PTK6 Signaling +8 more
		PTPN6	Unknown	28027327 31340200	Open Targets	Efferocytosis Adherens junction JAK-STAT signaling pathway +22 more
		PTPRB	Unknown	22722201 27535334 28027327 28153863	Open Targets	Adherens junction Neutrophil degranulation
		PTPRC	Unknown	22495314 22722193 27535334	Open Targets	Cell adhesion molecules T cell receptor signaling pathway Fc gamma R-mediated phagocytosis +5 more
		PTPRK	Unknown	28027327 30350370	Open Targets	EGFR downregulation
		PWWP2A	Unknown	27535334 28027327	Open Targets	—
		RABEP1	Unknown	22495314 22722193 28027327	Open Targets	Endocytosis TBC/RABGAPs
		RAD51	Unknown	28481359 30205045 37336919	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +8 more
		RAD51C	Unknown	22495314 22722193 27925203 28027327	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Homologous Recombination (HRR) +5 more
		RAP1GDS1	Unknown	28027327 20668451	Open Targets	—
		RARA	Unknown	28027327 30531871	Open Targets	Th17 cell differentiation Estrogen signaling pathway Pathways in cancer +6 more
		RASA1	Unknown	27535334 28027327 28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Axon guidance +5 more
		RBM10	Unknown	20668451 27535334 28027327 28481359 29349598 30205045 33942253	Open Targets	—
		RBM15	Unknown	22722193 28027327	Open Targets	—
		RECQL4	Unknown	20668451 27535334 28027327 28481359	Open Targets	—
		RET	Unknown	20668451 22538770 26527317 26968814 27284958 27531819 28027327 28153863 28481359 29807833 31340200 33942253 35657000 8545102	Open Targets	MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway +6 more
		RFWD3	Unknown	20668451 22722202 28153863	Open Targets	—
		ROS1	Unknown	20668451 22495314 28027327 28153863 28481359 30531871 31340200 35657000 37336919	Open Targets	—
		RPL10	Unknown	27535334 28027327	Open Targets	Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression +7 more
		RPL5	Unknown	28027327	Open Targets	Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression +7 more
		RPN1	Unknown	28027327 28153863	Open Targets	N-Glycan biosynthesis Various types of N-glycan biosynthesis Metabolic pathways +2 more
		RRAS2	Unknown	28027327	Open Targets	MAPK signaling pathway Ras signaling pathway cAMP signaling pathway +8 more
		SBDS	Unknown	28027327	Open Targets	Ribosome biogenesis in eukaryotes
		SDHB	Unknown	20668451 27245685	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SDHD	Unknown	28027327	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SET	Unknown	28027327 32043609	Open Targets	Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA
		SETD1B	Unknown	28027327	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		SETD2	Unknown	22495314 22722201 27284958 27535334 28027327 28153863 28481359 29349598 29807833 30062102 31340200	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		SETDB1	Unknown	27535334 28027327 31340200	Open Targets	Lysine degradation Metabolic pathways Signaling pathways regulating pluripotency of stem cells +1 more
		SFRP4	Unknown	27535334 28027327	Open Targets	Wnt signaling pathway
		SGK1	Unknown	31340200 35657000	Open Targets	FoxO signaling pathway Efferocytosis mTOR signaling pathway +6 more
		SIRPA	Unknown	28027327	Open Targets	Efferocytosis Osteoclast differentiation Cell surface interactions at the vascular wall +2 more
		SIX2	Unknown	27406316 28027327 30350370	Open Targets	—
		SMAD2	Unknown	22722201 26373574 27535334 28481359 30205045	Open Targets	Cell cycle Endocytosis Cellular senescence +30 more
		SMAD3	Unknown	28027327	Open Targets	FoxO signaling pathway Cell cycle Endocytosis +34 more
		SMAD4	Unknown	16627986 22722193 22722201 25695693 26373574 26527317 27245685 27531819 27566247 28027327 28481359 29202330 29214215 37336919 8653691	Open Targets	FoxO signaling pathway Hormone signaling Cell cycle +30 more
		SMARCD1	Unknown	22722201 30062102 30181556 30350370 31340200	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		SMARCE1	Unknown	22495314 22608084 27535334 28027327	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		SMO	Unknown	26960396 28027327 28153863 28481359 29202330 29807833 30205045 37336919	Open Targets	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		SND1	Unknown	22722193 27535334 28027327	Open Targets	Viral carcinogenesis Signaling by BRAF and RAF fusions
		SPECC1	Unknown	28027327 22495314	Open Targets	—
		SPEN	Unknown	22495314 22722193 22722201 26960396 27284958 27535334 27566247 27925203 28027327 28153863 28481359 29349598 30062102 30350370 33942253 34926230 37336919	Open Targets	Notch signaling pathway
		SPOP	Unknown	28027327 29349598	Open Targets	Hedgehog signaling pathway Hedgehog 'on' state
		SRC	Unknown	28027327 28153863 29807833 30350370 31340200 35657000 38970069	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +92 more
		STAG1	Unknown	22608084 22722193 22722201 22722202 27535334 28027327 28153863 31340200	Open Targets	Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion +4 more
		STAT3	Unknown	22495314 22722193 28027327 29349598 30531871 31867792	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		TBL1XR1	Unknown	27245685 27925203 28027327 28153863 31340200	Open Targets	Wnt signaling pathway RORA activates gene expression PPARA activates gene expression +11 more
		TCF12	Unknown	22495314 27245685 27535334 28027327 29214215	Open Targets	Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs NGF-stimulated transcription

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Female breast carcinoma

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