Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
female breast carcinoma	MONDO_0004379	ABI1	Unknown	28027327	Open Targets	Pathogenic Escherichia coli infection Salmonella infection Regulation of actin dynamics for phagocytic cup formation +3 more
		ABL1	Unknown	20668451 25695693 28027327 28153863 28481359 29202330 29349598 29807833 35657000	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ACKR3	Unknown	22495314	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine receptors bind chemokines +1 more
		ACSL6	Unknown	27535334 28027327	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +7 more
		AFDN	Unknown	22495314 22722201 22722202 28027327 29214215 31854063	Open Targets	Ras signaling pathway Rap1 signaling pathway cAMP signaling pathway +4 more
		AFF3	Unknown	22722193 27406316 28027327	Open Targets	—
		AKT1	Unknown	17611497 18676830 20101210 20668451 21512767 22538770 22722193 22722201 22840369 23144797 24318467 26373574 27531819 27535334 27925203 28027327 28481359 28685160 29202330 29349598 29807833 30181556 30205045 31340200 31693690 35657000	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		ALK	Unknown	18414414 19383809 20668451 22610646 22722201 23558953 23739063 26527317 27284958 27535334 28027327 28153863 28481359 29807833 30062102 30205045 30350370 31854063 33942253 35657000	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		APC	Unknown	10660330 18593979 19593635 20668451 22722193 22722201 26373574 26527317 26806567 26960396 27284958 27531819 27925203 28027327 28153863 28481359 28685160 29202330 29349598 29928447 30062102 30350370 31693690 31867792 32043609 33942253 35657000 37336919 7798298	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		APOBEC3B	Unknown	28027327	Open Targets	Viral life cycle - HIV-1 Human immunodeficiency virus 1 infection mRNA Editing: C to U Conversion +1 more
		ARAF	Unknown	28027327 35657000	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +41 more
		ARHGEF12	Unknown	20668451 28027327 32043609 33021035	Open Targets	Vascular smooth muscle contraction Axon guidance Platelet activation +12 more
		ARID1B	Unknown	22722201 27535334 28027327 28153863 29349598 30181556 31980561	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARNT	Unknown	28027327	Open Targets	HIF-1 signaling pathway Efferocytosis Cushing syndrome +10 more
		ASPSCR1	Unknown	22722202 27535334	Open Targets	Transcriptional misregulation in cancer
		ATP1A1	Unknown	27535334 28027327	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway Cardiac muscle contraction +18 more
		ATR	Unknown	22495314 22722193 22722201 25927147 26373574 26960396 27535334 28027327 28481359 29349598 29807833 30181556 31340200 35657000 37336919	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		ATRX	Unknown	22495314 27284958 27406316 27535334 27925203 28027327 28481359 29349598 30475948 31340200 37336919	Open Targets	Cell cycle
		AXIN1	Unknown	22722193 22722201 27284958 28153863 28481359 30205045	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		B2M	Unknown	22495314 22722201 28481359 30205045	Open Targets	Antigen processing and presentation Human cytomegalovirus infection Human T-cell leukemia virus 1 infection +14 more
		BAX	Unknown	27535334 28027327	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +52 more
		BAZ1A	Unknown	22495314 23558953 28027327	Open Targets	ATP-dependent chromatin remodeling
		BCL10	Unknown	27535334 28027327	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		BCL11A	Unknown	22495314 27535334 28027327 30062102	Open Targets	—
		BCORL1	Unknown	22495314 27284958 27406316 28027327 29349598 30350370 33942253	Open Targets	Polycomb repressive complex
		BIRC3	Unknown	28027327	Open Targets	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
		BLM	Unknown	27535334 28027327 31340200 33004031	Open Targets	Homologous recombination Fanconi anemia pathway Processive synthesis on the C-strand of the telomere +10 more
		BMPR1A	Unknown	22722193 28481359 35657000	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling TGF-beta signaling pathway +4 more
		BRAF	Unknown	12068308 17314276 18186519 18397470 18628094 19372580 19572105 19593635 20530683 20551065 20668451 22495314 22538770 22722193 23856246 24423920 26960396 27531819 27535334 28027327 28685160 29349598 29807833 30181556 31340200 32206360 34818649 35657000	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA2	Unknown	22495314 22722193 22722201 26373574 27194814 27284958 27566247 28027327 28153863 29349598 29807833 30181556 30205045 31340200 31854063 33942253 35657000 37336919 8640236 8640237	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRD4	Unknown	22495314 28153863 28481359 33021035 35657000	Open Targets	—
		BTG2	Unknown	28027327	Open Targets	RNA degradation TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		BUB1B	Unknown	22722201 27535334 28027327 30350370 35657000	Open Targets	Cell cycle Human T-cell leukemia virus 1 infection Inactivation of APC/C via direct inhibition of the APC/C complex +9 more
		CALR	Unknown	27535334 28027327	Open Targets	Protein processing in endoplasmic reticulum Phagosome Efferocytosis +14 more
		CAMTA1	Unknown	22495314 22722201 27535334 28027327	Open Targets	—
		CARD11	Unknown	22722201 22722202 28027327 28153863 30062102 33942253	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CASP3	Unknown	28027327	Open Targets	Platinum drug resistance MAPK signaling pathway p53 signaling pathway +53 more
		CBLB	Unknown	20668451	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +5 more
		CCNC	Unknown	28027327 22495314	Open Targets	PPARA activates gene expression Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription +3 more
		CCND1	Unknown	28027327 35657000	Open Targets	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CCND2	Unknown	28027327 20668451	Open Targets	FoxO signaling pathway Cell cycle p53 signaling pathway +18 more
		CCND3	Unknown	28027327 35657000	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +17 more
		CCNE1	Unknown	30062102 35657000	Open Targets	Cell cycle Oocyte meiosis p53 signaling pathway +24 more
		CD209	Unknown	28027327	Open Targets	Virion - Human immunodeficiency virus Virion - Flavivirus and Alphavirus Virion - Ebolavirus, Lyssavirus and Morbillivirus +7 more
		CD274	Unknown	30062102	Open Targets	Cell adhesion molecules PD-L1 expression and PD-1 checkpoint pathway in cancer PD-1 signaling
		CD28	Unknown	28027327	Open Targets	Cell adhesion molecules T cell receptor signaling pathway Intestinal immune network for IgA production +16 more
		CDH17	Unknown	28027327	Open Targets	Gastric cancer Adherens junctions interactions
		CDK4	Unknown	18186519 28685160 31340200	Open Targets	Endocrine resistance Cell cycle p53 signaling pathway +40 more
		CDK6	Unknown	28027327 26960396	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +27 more
		CEBPA	Unknown	28027327 29349598 30350370	Open Targets	Non-alcoholic fatty liver disease Pathways in cancer Transcriptional misregulation in cancer +3 more

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Female breast carcinoma

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