Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
female breast carcinoma	MONDO_0004379	FKBP9	Unknown	30531871	Open Targets	—
		FLCN	Unknown	22495314 27535334 28027327 28481359 30205045 31340200	Open Targets	mTOR signaling pathway Renal cell carcinoma Amino acids regulate mTORC1
		FLT3	Unknown	22495314 27284958 27535334 27566247 28027327 29202330 29349598 29807833 31340200 35657000	Open Targets	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		FNBP1	Unknown	27535334 28027327 30531871	Open Targets	Shigellosis Clathrin-mediated endocytosis
		FOXA1	Unknown	22495314 23856246 26960396 27502118 27535334 27925203 28027327 28481359 29807833 30181556 30531871 34818649 37336919	Open Targets	Estrogen-dependent gene expression
		FOXP1	Unknown	22495314 28027327 28481359 30205045	Open Targets	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		FOXR1	Unknown	28027327	Open Targets	—
		FSTL3	Unknown	28027327	Open Targets	Antagonism of Activin by Follistatin Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
		GATA2	Unknown	28481359 29349598 30205045	Open Targets	RUNX1 regulates transcription of genes involved in differentiation of HSCs Factors involved in megakaryocyte development and platelet production
		GATA3	Unknown	15361840 19189213 22722193 22722201 22767585 23856246 24758297 25200445 26960396 27135926 27245685 27284958 27535334 27925203 28027327 28481359 28580595 28685160 29349598 29807833 30062102 30181556 30205045 33004031 35657000	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation Parathyroid hormone synthesis, secretion and action +6 more
		GNAQ	Unknown	26527317 27535334 28027327 28153863	Open Targets	Rap1 signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +52 more
		GRM3	Unknown	22722201 28027327 30531871	Open Targets	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Glutamatergic synapse +3 more
		GTF2I	Unknown	28027327	Open Targets	Basal transcription factors cGMP-PKG signaling pathway
		H3C2	Unknown	22722201 22722202 28027327 28481359	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +27 more
		H4C9	Unknown	28027327	Open Targets	Neutrophil extracellular trap formation Alcoholism Viral carcinogenesis +33 more
		HLF	Unknown	22722202	Open Targets	—
		HNRNPA2B1	Unknown	28027327	Open Targets	Amyotrophic lateral sclerosis mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA +1 more
		HOOK3	Unknown	22722193 28027327	Open Targets	Motor proteins
		HRAS	Unknown	17314276 19372580 19593635 22722201 23856246 25679062 25695693 25927147 27531819 28027327 29202330 29708279 29807833 30062102 30350370 31693690 31867792 32197944 35657000 37336919	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		HSP90AA1	Unknown	27535334 28027327 28153863 29214215 31340200	Open Targets	Protein processing in endoplasmic reticulum PI3K-Akt signaling pathway Necroptosis +56 more
		ID3	Unknown	22722202	Open Targets	TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells NGF-stimulated transcription
		IGF2BP2	Unknown	22495314	Open Targets	Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
		IKZF1	Unknown	27535334 28027327 28481359	Open Targets	—
		IL21R	Unknown	20668451 26907767 27535334 28027327 28153863	Open Targets	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Th17 cell differentiation +2 more
		IL6ST	Unknown	28027327 29807833	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Signaling pathways regulating pluripotency of stem cells +12 more
		IL7R	Unknown	27535334 28027327	Open Targets	Cytokine-cytokine receptor interaction FoxO signaling pathway PI3K-Akt signaling pathway +7 more
		IRS4	Unknown	27535334 28027327 28153863 35657000	Open Targets	cGMP-PKG signaling pathway FoxO signaling pathway Hormone signaling +11 more
		ITK	Unknown	22495314 22722201 28027327 28153863 30350370 35657000	Open Targets	Chemokine signaling pathway T cell receptor signaling pathway Leukocyte transendothelial migration +2 more
		JAK1	Unknown	20668451 22722193 28027327 28481359 29214215 29349598 29807833 30181556 30205045 31340200 35657000	Open Targets	EGFR tyrosine kinase inhibitor resistance PI3K-Akt signaling pathway Necroptosis +48 more
		JAK2	Unknown	20393555 22722202 27406316 27925203 28027327 29807833 30062102 30181556 33004031 35657000	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway Hormone signaling +51 more
		KEAP1	Unknown	22348534 27284958 27535334 28027327 38970069	Open Targets	Ubiquitin mediated proteolysis Parkinson disease Pathways in cancer +6 more
		KIT	Unknown	22538770 22722193 26527317 26968814 27531819 27535334 28027327 28153863 29202330 29807833 30181556 35657000	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KLF6	Unknown	28027327 22495314	Open Targets	—
		KNL1	Unknown	20668451 28027327 28153863 30531871	Open Targets	Cell cycle Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids +5 more
		LASP1	Unknown	27535334 28027327	Open Targets	—
		LATS1	Unknown	20668451 22495314 23856246 28027327 28481359 30062102 35657000	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LATS2	Unknown	22495314 22722201 28027327 31340200 35657000	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LCK	Unknown	28027327 35657000	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Natural killer cell mediated cytotoxicity +27 more
		LCP1	Unknown	28027327 22495314	Open Targets	Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
		LHFPL6	Unknown	20668451	Open Targets	—
		LMNA	Unknown	28027327	Open Targets	Apoptosis Cytoskeleton in muscle cells Hypertrophic cardiomyopathy +8 more
		LMO2	Unknown	28027327	Open Targets	Transcriptional misregulation in cancer RUNX1 regulates transcription of genes involved in differentiation of HSCs
		LOC100506403	Unknown	22722193 22722202 24416132 26373574 27245685 27284958 28027327 28153863 28481359 29349598 29807833 30062102 30181556 30350370 37336919	Open Targets	—
		LOC105376156	Unknown	22722202 28027327 28153863 31340200	Open Targets	—
		LPP	Unknown	20668451	Open Targets	—
		LRIG3	Unknown	28027327 30350370	Open Targets	—
		LSM14A	Unknown	22495314	Open Targets	—
		LZTR1	Unknown	27535334 28027327	Open Targets	—
		MAFB	Unknown	28027327 28153863	Open Targets	Parathyroid hormone synthesis, secretion and action
		MAP2K2	Unknown	35657000	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +87 more

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Female breast carcinoma

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