Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
COLORECTAL NEOPLASMS	MESH:D015179	TCERG1L	Unknown	21278247	CTD	—
		TCF7L2	Unknown	21892161 24836286	CTD	Wnt signaling pathway Hippo signaling pathway Adherens junction +26 more
		TCN2	Unknown	17389618	CTD	Vitamin digestion and absorption Cobalamin transport and metabolism Cobalamin (Cbl, vitamin B12) transport and metabolism +2 more
		TET2	Unknown	30510241	CTD	—
		TFPI2	Unknown	19435926	CTD	—
		TFRC	Unknown	16111806	CTD	Virion - Lassa virus and SFTS virus HIF-1 signaling pathway Endocytosis +8 more
		TGFB1	Unknown	24836286	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +49 more
		TGFBR1	Unknown	18703712	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more
		TK1	Unknown	15814641	CTD	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		TLR2	Unknown	16879199 17892325	CTD	Phagosome PI3K-Akt signaling pathway Neutrophil extracellular trap formation +30 more
		TLR4	Unknown	16879199 22180778	CTD	NF-kappa B signaling pathway HIF-1 signaling pathway Phagosome +41 more
		TMEM238L	Unknown	30510241	CTD	—
		TNF	Unknown	23431386	CTD	Antifolate resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +72 more
		TNFSF10	Unknown	17273769	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor FoxO signaling pathway +13 more
		TNFSF13	Unknown	18423122	CTD	Cytokine-cytokine receptor interaction Intestinal immune network for IgA production Rheumatoid arthritis +2 more
		TP53	Unknown	12645814 15172127 15814641 16110022 16524972 17949449 18676755 21946351	CTD	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TP63	Unknown	15875781	CTD	MicroRNAs in cancer Activation of PUMA and translocation to mitochondria TP53 Regulates Metabolic Genes +5 more
		TRIM28	Unknown	30510241	CTD	Generic Transcription Pathway SUMOylation of transcription cofactors HCMV Early Events
		TRPM7	Unknown	17823441	CTD	Necroptosis Cellular senescence NOD-like receptor signaling pathway +2 more
		TXNRD1	Unknown	18483336	CTD	Selenocompound metabolism Pathways in cancer Hepatocellular carcinoma +6 more
		TYMP	Unknown	15706408 17047489	CTD	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways +4 more
		TYMS	Unknown	15222106 15386371 15500737 16141798 16943523 17047489 17943475 18607850 18676755 19020767 25944804	CTD	Pyrimidine metabolism One carbon pool by folate Metabolic pathways +5 more
		UMPS	Unknown	15814641 19020767	CTD	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		UNG	Unknown	15814641	CTD	Base excision repair Primary immunodeficiency Recognition and association of DNA glycosylase with site containing an affected pyrimidine +2 more
		VTI1A	Unknown	21892161	CTD	SNARE interactions in vesicular transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
		WIF1	Unknown	17923031	CTD	Wnt signaling pathway
		XAF1	Unknown	17570219	CTD	Interferon alpha/beta signaling
		YAP1	Unknown	30510241 34351699	CTD	Hippo signaling pathway Hippo signaling pathway - multiple species Nuclear signaling by ERBB4 +5 more
		ZFP36L2	Unknown	25944804	CTD	Cellular senescence
		ZKSCAN3	Unknown	18519692	CTD	Generic Transcription Pathway
		ZMIZ1	Unknown	24836286	CTD	—
		ZNF292	Unknown	25559195	CTD	—
		ZNF367	Unknown	34351699	CTD	—
		ZNF432	Unknown	18507500	CTD	Generic Transcription Pathway
		ZNF569	Unknown	21278247	CTD	Generic Transcription Pathway
		ZYX	Unknown	30697742	CTD	Focal adhesion Cytoskeleton in muscle cells
COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS	MESH:D003123	CD44	Unknown	28255344	CTD	ECM-receptor interaction Hematopoietic cell lineage Shigellosis +9 more
		EPCAM	Unknown	25701956	CTD	Virion - Hepatitis viruses Cell surface interactions at the vascular wall
		MSH6	Unknown	11586295 18417481 22102614 25701956 9354786	CTD	Platinum drug resistance Mismatch repair Pathways in cancer +4 more
		PMS2	Unknown	14756672 15887124 25701956	CTD	Mismatch repair Fanconi anemia pathway Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) +3 more
		TGFBR2	Unknown	9590282	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more

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Colorectal neoplasms

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