Colorectal cancer

Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) G alpha (q) signalling events

EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway Endocytosis PI3K-Akt signaling pathway Signaling pathways regulating pluripotency of stem cells Regulation of actin cytoskeleton Pathways in cancer MicroRNAs in cancer Bladder cancer Central carbon metabolism in cancer PI3K Cascade PIP3 activates AKT signaling Signaling by activated point mutants of FGFR3 FGFR3b ligand binding and activation FGFR3c ligand binding and activation FGFR3 mutant receptor activation t(4;14) translocations of FGFR3 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade; FGFR3 SHC-mediated cascade:FGFR3 FRS-mediated FGFR3 signaling PI-3K cascade:FGFR3 Negative regulation of FGFR3 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Signaling by FGFR3 fusions in cancer Signaling by FGFR3 point mutants in cancer +27 more

Purine metabolism Metabolic pathways Small cell lung cancer Non-small cell lung cancer +1 more

Cytoskeleton in muscle cells

Estrogen signaling pathway HSP90 chaperone cycle for steroid hormone receptors (SHR) ESR-mediated signaling

Cytoskeleton in muscle cells

MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells

Reversal of alkylation damage by DNA dioxygenases

Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways Lewis blood group biosynthesis Reactions specific to the complex N-glycan synthesis pathway +1 more

Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways Lewis blood group biosynthesis

Mannose type O-glycan biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Glycosphingolipid biosynthesis - globo and isoglobo series Metabolic pathways Lewis blood group biosynthesis +2 more

Porphyrin metabolism Mitochondrial protein import Mitochondrial iron-sulfur cluster biogenesis

Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling Serotonergic synapse GABAergic synapse Morphine addiction Nicotine addiction GABA receptor activation +4 more

Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways Defective GALNT12 causes colorectal cancer 1 (CRCS1) O-linked glycosylation of mucins +2 more

Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways O-linked glycosylation of mucins +1 more

Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways FGFR3c ligand binding and activation Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) O-linked glycosylation of mucins +3 more

Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways O-linked glycosylation of mucins +1 more

Th1 and Th2 cell differentiation Th17 cell differentiation Parathyroid hormone synthesis, secretion and action Inflammatory bowel disease Ub-specific processing proteases Interleukin-4 and Interleukin-13 signaling RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Factors involved in megakaryocyte development and platelet production +6 more

Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways Biosynthesis of nucleotide sugars Insulin resistance Diabetic cardiomyopathy Synthesis of UDP-N-acetyl-glucosamine +4 more

Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways Biosynthesis of cofactors Gamma-carboxylation of protein precursors +1 more

cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling Insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production +5 more

MAPK signaling pathway cGMP-PKG signaling pathway Sphingolipid signaling pathway Phospholipase D signaling pathway Hormone signaling Vascular smooth muscle contraction Long-term depression Regulation of actin cytoskeleton Parathyroid hormone synthesis, secretion and action Pathogenic Escherichia coli infection Human cytomegalovirus infection Pathways in cancer G alpha (12/13) signalling events Thrombin signalling through proteinase activated receptors (PARs) +11 more

Endocrine resistance Rap1 signaling pathway Calcium signaling pathway cAMP signaling pathway Phospholipase D signaling pathway Hormone signaling Adrenergic signaling in cardiomyocytes Vascular smooth muscle contraction Gap junction Platelet activation Circadian entrainment Thermogenesis Glutamatergic synapse Serotonergic synapse Dopaminergic synapse Long-term depression Inflammatory mediator regulation of TRP channels Insulin secretion GnRH signaling pathway Ovarian steroidogenesis Estrogen signaling pathway Melanogenesis Thyroid hormone synthesis Oxytocin signaling pathway Glucagon signaling pathway Regulation of lipolysis in adipocytes Renin secretion Aldosterone synthesis and secretion Relaxin signaling pathway Cortisol synthesis and secretion Parathyroid hormone synthesis, secretion and action Cushing syndrome Growth hormone synthesis, secretion and action Endocrine and other factor-regulated calcium reabsorption Vasopressin-regulated water reabsorption Salivary secretion Gastric acid secretion Pancreatic secretion Bile secretion Parkinson disease Cocaine addiction Amphetamine addiction Morphine addiction Alcoholism Vibrio cholerae infection Chagas disease Amoebiasis Human cytomegalovirus infection Human papillomavirus infection Pathways in cancer Chemical carcinogenesis - receptor activation Dilated cardiomyopathy Glucagon signaling in metabolic regulation PKA activation in glucagon signalling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Prostacyclin signalling through prostacyclin receptor G alpha (s) signalling events Glucagon-type ligand receptors Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production +58 more

MAPK signaling pathway Ras signaling pathway Chemokine signaling pathway Hormone signaling PI3K-Akt signaling pathway Apelin signaling pathway Circadian entrainment Retrograde endocannabinoid signaling Glutamatergic synapse Cholinergic synapse Serotonergic synapse GABAergic synapse Dopaminergic synapse Regulation of actin cytoskeleton Relaxin signaling pathway Morphine addiction Alcoholism Human cytomegalovirus infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Pathways in cancer Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits +45 more

Retrograde transport at the Trans-Golgi-Network Signaling by membrane-tethered fusions of PDGFRA or PDGFRB

ECM-receptor interaction Platelet activation GPVI-mediated activation cascade Cell surface interactions at the vascular wall Platelet Adhesion to exposed collagen +2 more

A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Release of Hh-Np from the secreting cell Retinoid metabolism and transport +7 more

A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Retinoid metabolism and transport +6 more

Amine ligand-binding receptors G alpha (q) signalling events

Neuroactive ligand-receptor interaction G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production

Glutathione metabolism Arachidonic acid metabolism Metabolic pathways Ferroptosis Synthesis of 12-eicosatetraenoic acid derivatives Synthesis of 15-eicosatetraenoic acid derivatives Biosynthesis of D-series resolvins Biosynthesis of E-series 18(S)-resolvins Biosynthesis of aspirin-triggered D-series resolvins Biosynthesis of E-series 18(R)-resolvins +7 more

Glycine, serine and threonine metabolism Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Metabolic pathways Glyoxylate metabolism and glycine degradation +2 more

cAMP signaling pathway Neuroactive ligand-receptor interaction Circadian entrainment Long-term potentiation Retrograde endocannabinoid signaling Glutamatergic synapse Dopaminergic synapse Long-term depression Amyotrophic lateral sclerosis Huntington disease Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases Amphetamine addiction Nicotine addiction COPII-mediated vesicle transport Activation of AMPA receptors Trafficking of AMPA receptors Trafficking of GluR2-containing AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Cargo concentration in the ER Synaptic adhesion-like molecules +18 more