Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
COLORECTAL CANCER	MONDO_0005575	MELK	Unknown	38538606	GWAS catalog	—
		METRNL	Unknown	30510241 31089142 34594039 34671089 36539618 37340002 38538606 38872215	GWAS catalog	—
		MGAT5	Unknown	37890997	GWAS catalog	N-Glycan biosynthesis Metabolic pathways N-Glycan antennae elongation
		MGAT5B	Unknown	26621817	GWAS catalog	N-Glycan biosynthesis Mannose type O-glycan biosynthesis Metabolic pathways
		MIER3	Unknown	32887889	GWAS catalog	—
		MLC1	Unknown	34290314	GWAS catalog	—
		MLH1	Unknown	33632709	GWAS catalog	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MLLT10	Unknown	32887889	GWAS catalog	—
		MMP2	Unknown	27207650	GWAS catalog	Endocrine resistance Leukocyte transendothelial migration GnRH signaling pathway +15 more
		MMP9	Unknown	34290314	GWAS catalog	Endocrine resistance IL-17 signaling pathway TNF signaling pathway +22 more
		MORC1	Unknown	24743840	GWAS catalog	—
		MORC3	Unknown	35512400	GWAS catalog	—
		MPHOSPH8	Unknown	34062886	GWAS catalog	—
		MRO	Unknown	33976257	GWAS catalog	—
		MRPS6	Unknown	29228715	GWAS catalog	Ribosome Mitochondrial translation elongation Mitochondrial translation termination
		MRTFA	Unknown	32887889 37340002	GWAS catalog	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSMB	Unknown	32887889	GWAS catalog	—
		MSRA	Unknown	38538606	GWAS catalog	Protein repair
		MTAP	Unknown	27197191	GWAS catalog	Cysteine and methionine metabolism Metabolic pathways Methionine salvage pathway +1 more
		MTUS2	Unknown	38538606	GWAS catalog	—
		MTX1	Unknown	27197191	GWAS catalog	Mitophagy - animal
		MUC22	Unknown	30510241 36539618	GWAS catalog	—
		MXRA8	Unknown	27197191	GWAS catalog	Virion - Flavivirus and Alphavirus Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
		MYEOV	Unknown	27197191 32887889	GWAS catalog	—
		MYL2	Unknown	31826910 35512400 38872215	GWAS catalog	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Apelin signaling pathway +12 more
		MYNN	Unknown	20972440 30529582 31826910 36539618	GWAS catalog	—
		MYO16	Unknown	29228715 35512400	GWAS catalog	Motor proteins
		MYO18A	Unknown	38538606	GWAS catalog	Motor proteins Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease
		MYO9B	Unknown	34290314	GWAS catalog	Motor proteins Rho GTPase cycle Regulation of actin dynamics for phagocytic cup formation +2 more
		MYRF	Unknown	24836286 26965516 29471430 30510241 30529582 36539618 37340002	GWAS catalog	—
		MZF1	Unknown	30510241	GWAS catalog	—
		NAA25	Unknown	34594039	GWAS catalog	—
		NABP1	Unknown	23266556	GWAS catalog	RNA polymerase II transcribes snRNA genes
		NACAD	Unknown	30510241 34594039 38872215	GWAS catalog	—
		NALF1	Unknown	35512400	GWAS catalog	—
		NASP	Unknown	38408508	GWAS catalog	—
		NAV1	Unknown	40155373	GWAS catalog	—
		NAV3	Unknown	37890997	GWAS catalog	—
		NCOA6	Unknown	34290314	GWAS catalog	RORA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis +4 more
		NDUFA10	Unknown	35512400	GWAS catalog	Oxidative phosphorylation Metabolic pathways Thermogenesis +12 more
		NDUFS4	Unknown	38538606	GWAS catalog	Oxidative phosphorylation Metabolic pathways Thermogenesis +12 more
		NEGR1	Unknown	38749303	GWAS catalog	Cell adhesion molecules Post-translational modification: synthesis of GPI-anchored proteins
		NEK10	Unknown	27197191 32887889	GWAS catalog	—
		NFILZ	Unknown	38538606	GWAS catalog	—
		NFKBIZ	Unknown	31826910	GWAS catalog	Transcriptional misregulation in cancer
		NHLRC1	Unknown	29299148 38411962	GWAS catalog	Ubiquitin mediated proteolysis Glycogen synthesis Myoclonic epilepsy of Lafora
		NID2	Unknown	36539618	GWAS catalog	Cytoskeleton in muscle cells Laminin interactions
		NKX1-1	Unknown	38538606	GWAS catalog	—
		NKX2-3	Unknown	24737748 25990418 26151821 29917119 30510241 31089142 36539618 38872215	GWAS catalog	—
		NKX2-6	Unknown	31826910 36539618	GWAS catalog	—

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Colorectal cancer

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