Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
breast carcinoma by gene expression profile	MONDO_0006116	SF3B1	Unknown	28270497 25850943 32723837 27502118 30181556 30537512	Open Targets	Spliceosome B-WICH complex positively regulates rRNA expression mRNA Splicing - Major Pathway +1 more
		SH2B3	Unknown	30537512	Open Targets	Neurotrophin signaling pathway Regulation of KIT signaling Factors involved in megakaryocyte development and platelet production
		SIRPA	Unknown	24185510	Open Targets	Efferocytosis Osteoclast differentiation Cell surface interactions at the vascular wall +2 more
		SKI	Unknown	24185510	Open Targets	TGF-beta signaling pathway Signaling by BMP Downregulation of SMAD2/3:SMAD4 transcriptional activity
		SMAD2	Unknown	30537512	Open Targets	Cell cycle Endocytosis Cellular senescence +30 more
		SMAD4	Unknown	24185512 26527317 30537512	Open Targets	FoxO signaling pathway Hormone signaling Cell cycle +30 more
		SMARCA4	Unknown	24185510 29807833 30537512	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +6 more
		SMARCB1	Unknown	30537512	Open Targets	ATP-dependent chromatin remodeling Viral life cycle - HIV-1 Thermogenesis +3 more
		SMARCD1	Unknown	26563128 30537512 30181556 28270497	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		SMO	Unknown	30914635 30537512 24185512 29807833	Open Targets	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		SOCS1	Unknown	30537512	Open Targets	Ubiquitin mediated proteolysis Osteoclast differentiation JAK-STAT signaling pathway +13 more
		SOS1	Unknown	30537512 30531871	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +97 more
		SPEN	Unknown	26297734 30537512 26960396 29807833	Open Targets	Notch signaling pathway
		SPOP	Unknown	30537512	Open Targets	Hedgehog signaling pathway Hedgehog 'on' state
		SRSF2	Unknown	30537512	Open Targets	Spliceosome Herpes simplex virus 1 infection Transport of Mature mRNA derived from an Intron-Containing Transcript +4 more
		STAG2	Unknown	30205045 30537512	Open Targets	Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion +4 more
		STAT3	Unknown	25850943	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		STK11	Unknown	30914635 28580595 30062102 30537512	Open Targets	FoxO signaling pathway Hormone signaling Autophagy - animal +9 more
		STRN	Unknown	27406316	Open Targets	PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling +2 more
		SUZ12	Unknown	30537512	Open Targets	Polycomb repressive complex PRC2 methylates histones and DNA Oxidative Stress Induced Senescence +5 more
		SYK	Unknown	30205045 30537512	Open Targets	NF-kappa B signaling pathway Phospholipase D signaling pathway PI3K-Akt signaling pathway +30 more
		TBX3	Unknown	26563128 30537512 26960396 30181556 28270497	Open Targets	Signaling pathways regulating pluripotency of stem cells
		TCF3	Unknown	30537512	Open Targets	Signaling pathways regulating pluripotency of stem cells Human T-cell leukemia virus 1 infection Transcriptional misregulation in cancer +2 more
		TERT	Unknown	30537512 24185512 30205045 30062102 29807833	Open Targets	Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer +4 more
		TET1	Unknown	32723837 30537512	Open Targets	—
		TET2	Unknown	25850943 30062102 30537512	Open Targets	—
		TGFBR2	Unknown	30537512	Open Targets	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more
		TMEM127	Unknown	30537512	Open Targets	—
		TNC	Unknown	24185510	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +6 more
		TNFAIP3	Unknown	30537512	Open Targets	NF-kappa B signaling pathway Necroptosis NOD-like receptor signaling pathway +10 more
		TNFRSF14	Unknown	30537512	Open Targets	Virion - Herpesvirus Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor +3 more
		TOP1	Unknown	24185510 30537512	Open Targets	SUMOylation of DNA replication proteins
		TP53	Unknown	27406316 25979954 30062102 21512767 30205045 26527317 24185512 30914635 25850943 30531871 24185510 32723837 27566247 29807833 28270497 26563128 27135926 27502118 30181556 30537512	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TP63	Unknown	30537512	Open Targets	MicroRNAs in cancer Activation of PUMA and translocation to mitochondria TP53 Regulates Metabolic Genes +5 more
		TPR	Unknown	30375428 30531871	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis Pathways in cancer +27 more
		TRAF7	Unknown	30537512	Open Targets	Antigen processing: Ubiquitination & Proteasome degradation
		TRRAP	Unknown	30062102	Open Targets	ATP-dependent chromatin remodeling Human T-cell leukemia virus 1 infection Formation of the beta-catenin:TCF transactivating complex +1 more
		TSC1	Unknown	30537512 30205045 30531871	Open Targets	Phospholipase D signaling pathway Autophagy - animal mTOR signaling pathway +15 more
		TSC2	Unknown	30205045 30537512 29807833	Open Targets	Phospholipase D signaling pathway p53 signaling pathway Autophagy - animal +19 more
		TSHR	Unknown	24185512 30537512	Open Targets	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +6 more
		U2AF1	Unknown	30537512	Open Targets	Spliceosome Shigellosis Transport of Mature mRNA derived from an Intron-Containing Transcript +3 more
		USP6	Unknown	30531871	Open Targets	—
		VHL	Unknown	26527317	Open Targets	HIF-1 signaling pathway Ubiquitin mediated proteolysis Pathways in cancer +5 more
		WRN	Unknown	30531871	Open Targets	Processive synthesis on the C-strand of the telomere Removal of the Flap Intermediate from the C-strand SUMOylation of DNA damage response and repair proteins +9 more
		WT1	Unknown	30537512	Open Targets	Transcriptional misregulation in cancer
		XPO1	Unknown	30537512 30531871	Open Targets	Ribosome biogenesis in eukaryotes Nucleocytoplasmic transport Viral life cycle - HIV-1 +15 more
		YAP1	Unknown	25850943 30537512	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Nuclear signaling by ERBB4 +5 more
		ZEB1	Unknown	30531871	Open Targets	Transcriptional misregulation in cancer MicroRNAs in cancer Prostate cancer +1 more
		ZFHX3	Unknown	31854063 26960396 30537512	Open Targets	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
		ZNF521	Unknown	27406316	Open Targets	—

«‹1…5 678 ›»

Breast carcinoma by gene expression profile

Bookmark This Disease