Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
breast carcinoma by gene expression profile	MONDO_0006116	HLA-A	Unknown	24185510	Open Targets	Endocytosis Phagosome Cellular senescence +25 more
		HNF1A	Unknown	30914635 30537512 25850943	Open Targets	Maturity onset diabetes of the young
		HOXD13	Unknown	27406316	Open Targets	—
		HRAS	Unknown	30537512 25850943	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		IDH1	Unknown	30205045 24185512 30537512	Open Targets	Citrate cycle (TCA cycle) Glutathione metabolism Metabolic pathways +9 more
		IDH2	Unknown	24185512 30537512	Open Targets	Citrate cycle (TCA cycle) Glutathione metabolism Metabolic pathways +7 more
		IKZF1	Unknown	30205045 30537512	Open Targets	—
		IKZF3	Unknown	30062102	Open Targets	—
		IL6ST	Unknown	25850943	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Signaling pathways regulating pluripotency of stem cells +12 more
		IL7R	Unknown	30537512	Open Targets	Cytokine-cytokine receptor interaction FoxO signaling pathway PI3K-Akt signaling pathway +7 more
		IRF4	Unknown	27406316 30537512	Open Targets	Th17 cell differentiation Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling +1 more
		IRS4	Unknown	24185510	Open Targets	cGMP-PKG signaling pathway FoxO signaling pathway Hormone signaling +11 more
		JAK1	Unknown	30062102 24185512 25850943 28270497 30181556 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance PI3K-Akt signaling pathway Necroptosis +48 more
		JAK2	Unknown	30537512 24185512 25850943 30181556 28270497	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway Hormone signaling +51 more
		JAK3	Unknown	24185512 30537512	Open Targets	Chemokine signaling pathway PI3K-Akt signaling pathway Necroptosis +21 more
		JUN	Unknown	30537512	Open Targets	Endocrine resistance MAPK signaling pathway ErbB signaling pathway +63 more
		KAT6A	Unknown	30062102 24185510 30531871	Open Targets	Signaling pathways regulating pluripotency of stem cells HATs acetylate histones Regulation of TP53 Activity through Acetylation
		KAT6B	Unknown	30062102 25850943	Open Targets	HATs acetylate histones
		KDM5A	Unknown	24185510 30537512	Open Targets	HDMs demethylate histones
		KDM5C	Unknown	24185512 30537512	Open Targets	HDMs demethylate histones
		KDM6A	Unknown	30537512 24185512 25850943	Open Targets	Transcriptional misregulation in cancer HDMs demethylate histones
		KDR	Unknown	30537512 30205045 26527317 29807833 25850943	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KEAP1	Unknown	30537512	Open Targets	Ubiquitin mediated proteolysis Parkinson disease Pathways in cancer +6 more
		KIAA1549	Unknown	24185510	Open Targets	Signaling by BRAF and RAF fusions
		KIT	Unknown	28270497 30062102 30914635 30205045 26527317 29807833 27502118 30181556 30537512	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KLF4	Unknown	30537512	Open Targets	Signaling pathways regulating pluripotency of stem cells Chemical carcinogenesis - receptor activation Synthesis, secretion, and deacylation of Ghrelin +1 more
		KMT2A	Unknown	30181556 30205045 24185512 25850943 28270497 27502118 24185510 30537512	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KMT2C	Unknown	27406316 28270497 30062102 30205045 24185512 25850943 30531871 27195705 32723837 26563128 27502118 30181556 30537512	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		KMT2D	Unknown	30062102 24185512 25850943 28270497 26563128 27502118 30181556 30537512	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KNL1	Unknown	27406316 30375428	Open Targets	Cell cycle Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids +5 more
		KRAS	Unknown	30914635 30537512 26527317 30181556 25850943	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LATS1	Unknown	30537512	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LATS2	Unknown	30537512	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LCK	Unknown	27406316	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Natural killer cell mediated cytotoxicity +27 more
		LMNA	Unknown	30531871	Open Targets	Apoptosis Cytoskeleton in muscle cells Hypertrophic cardiomyopathy +8 more
		LOC100506403	Unknown	28270497 30062102 30205045 24185512 30531871 27502118 30181556 30537512	Open Targets	—
		LOC105376156	Unknown	30537512	Open Targets	—
		LYN	Unknown	27502118	Open Targets	Chemokine signaling pathway NF-kappa B signaling pathway Platelet activation +36 more
		LZTR1	Unknown	30531871	Open Targets	—
		MACC1	Unknown	24185510	Open Targets	—
		MALT1	Unknown	30537512	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		MAML2	Unknown	24185510	Open Targets	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MAP2K1	Unknown	30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MAP2K2	Unknown	24185512 30062102 29807833	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +87 more
		MAP2K4	Unknown	30062102 24185512 25850943 30531871 28270497 26563128 30181556 30537512	Open Targets	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway +21 more
		MAP3K1	Unknown	30205045 28580595 24185512 25850943 26960396 28270497 26563128 27502118 30181556 30537512	Open Targets	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K13	Unknown	30062102 27502118 30181556 28270497	Open Targets	MAPK signaling pathway
		MAPK1	Unknown	30205045 30537512	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +161 more
		MAX	Unknown	30537512	Open Targets	Polycomb repressive complex MAPK signaling pathway Pathways in cancer +6 more
		MDM2	Unknown	30531871 30537512 28270497	Open Targets	Endocrine resistance Platinum drug resistance FoxO signaling pathway +35 more

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Breast carcinoma by gene expression profile

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