Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
BIPOLAR DISORDER	MONDO_0004985 C0005586 MESH:D001714	AMIGO1	Unknown	34099189	GWAS catalog	—
		AMPD3	Unknown	20713499	GWAS catalog	Purine metabolism Metabolic pathways Nucleotide metabolism +3 more
		ANAPC7	Unknown	33686288	GWAS catalog	Cell cycle Oocyte meiosis Ubiquitin mediated proteolysis +18 more
		ANK3	Unknown	18711365 21926974 31043756 20351715 21926972 22182935 23453885 24618891 28072414 33263727 34002096 38154582	CTD, Disgenet, GWAS catalog	Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins +1 more
		ANKHD1	Unknown	31043756	GWAS catalog	—
		ANKHD1-EIF4EBP3	Unknown	31043756	GWAS catalog	—
		ANKK1	Unknown	—	Disgenet	—
		ANKRD11	Unknown	39024449	GWAS catalog	—
		ANKRD23	Unknown	31043756 38154582	GWAS catalog	Cytoskeleton in muscle cells
		ANKRD6	Unknown	25827505	GWAS catalog	—
		ANKS1B	Unknown	23453885 31043756 31835028 32606422 33479212 34159505	GWAS catalog	—
		ANTXR2	Unknown	25781172	GWAS catalog	NOD-like receptor signaling pathway Uptake and function of anthrax toxins
		ANXA1	Unknown	20713499	GWAS catalog	G alpha (q) signalling events G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands +1 more
		APOB	Unknown	24882193	GWAS catalog	Fat digestion and absorption Vitamin digestion and absorption Cholesterol metabolism +20 more
		APOD	Unknown	—	Disgenet	Transport of fatty acids NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
		APOE	Unknown	—	Disgenet	Cholesterol metabolism Alzheimer disease Nuclear signaling by ERBB4 +10 more
		APP	Unknown	—	Disgenet	Serotonergic synapse Alzheimer disease Pathways of neurodegeneration - multiple diseases +16 more
		ARB2A	Unknown	31926635	GWAS catalog	—
		ARC	Unknown	20889312	GWAS catalog	Amphetamine addiction NGF-stimulated transcription
		AREL1	Unknown	31926635	GWAS catalog	Antigen processing: Ubiquitination & Proteasome degradation
		ARHGAP15	Unknown	31926635	GWAS catalog	Rho GTPase cycle
		ARHGEF10	Unknown	—	Disgenet	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARHGEF15	Unknown	28115744	GWAS catalog	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARL3	Unknown	31835028	GWAS catalog	Trafficking of myristoylated proteins to the cilium
		ARRB2	Unknown	—	Disgenet	MAPK signaling pathway Chemokine signaling pathway Endocytosis +21 more
		ARSG	Unknown	25781172	GWAS catalog	Lysosome Glycosphingolipid metabolism The activation of arylsulfatases
		AS3MT	Unknown	23453885	GWAS catalog	Chemical carcinogenesis - reactive oxygen species Methylation
		ASAP2	Unknown	31043756	GWAS catalog	Endocytosis Fc gamma R-mediated phagocytosis
		ASCC2	Unknown	27890468	GWAS catalog	ALKBH3 mediated reversal of alkylation damage
		ASCC3	Unknown	31926635	GWAS catalog	ALKBH3 mediated reversal of alkylation damage
		ASMT	Unknown	—	Disgenet	Tryptophan metabolism Metabolic pathways Serotonin and melatonin biosynthesis
		ASTN2	Unknown	31043756 31926635	Disgenet, GWAS catalog	—
		ASXL3	Unknown	31926635	GWAS catalog	Polycomb repressive complex
		ATCAY	Unknown	34099189	GWAS catalog	—
		ATF4	Unknown	—	Disgenet	MAPK signaling pathway cGMP-PKG signaling pathway Mitophagy - animal +41 more
		ATF5	Unknown	—	Disgenet	—
		ATP13A4	Unknown	31926635	GWAS catalog	Ion transport by P-type ATPases
		ATP1A1	Unknown	—	Disgenet	cGMP-PKG signaling pathway cAMP signaling pathway Cardiac muscle contraction +18 more
		ATP1A2	Unknown	—	Disgenet	cGMP-PKG signaling pathway cAMP signaling pathway Cardiac muscle contraction +18 more
		ATP1A3	Unknown	—	Disgenet	cGMP-PKG signaling pathway cAMP signaling pathway Cardiac muscle contraction +18 more
		ATP1B3	Unknown	38858783	GWAS catalog	cGMP-PKG signaling pathway cAMP signaling pathway Cardiac muscle contraction +19 more
		ATP2A2	Unknown	31043756 31835028	GWAS catalog	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +16 more
		ATP2B2	Unknown	31043756 34002096	GWAS catalog	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +9 more
		ATP5PD	Unknown	31043756	GWAS catalog	Oxidative phosphorylation Metabolic pathways Thermogenesis +10 more
		ATP6V1B2	Unknown	20889312	GWAS catalog	Oxidative phosphorylation Metabolic pathways Phagosome +12 more
		ATP6V1G3	Unknown	33686288	GWAS catalog	Oxidative phosphorylation Metabolic pathways Phagosome +12 more
		ATP6V1H	Unknown	23092984	GWAS catalog	Oxidative phosphorylation Metabolic pathways Lysosome +16 more
		ATP8A2	Unknown	20889312	GWAS catalog	Efferocytosis Ion transport by P-type ATPases
		ATP8B3	Unknown	19416921	GWAS catalog	Ion transport by P-type ATPases
		ATRNL1	Unknown	27890468	GWAS catalog	—
BIPOLAR I DISORDER	EFO_0009963	ANK3	Unknown	31043756 34002096	GWAS catalog	Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins +1 more
		ANKHD1	Unknown	31043756	GWAS catalog	—
		ANKHD1-EIF4EBP3	Unknown	31043756	GWAS catalog	—
		ANKRD23	Unknown	31043756	GWAS catalog	Cytoskeleton in muscle cells
		ANKS1B	Unknown	31043756	GWAS catalog	—
		ASTN2	Unknown	31043756	GWAS catalog	—
		ATP2A2	Unknown	31043756	GWAS catalog	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +16 more
		ATP2B2	Unknown	34002096	GWAS catalog	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +9 more
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	C0024713	ANK3	Unknown	—	Disgenet	Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins +1 more
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	C0024713	ATP1A3	Unknown	—	Disgenet	cGMP-PKG signaling pathway cAMP signaling pathway Cardiac muscle contraction +18 more
MIXED BIPOLAR I DISORDER	C0236780	ANK3	Unknown	—	Disgenet	Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins +1 more
MIXED BIPOLAR I DISORDER	C0236780	ATP1A3	Unknown	—	Disgenet	cGMP-PKG signaling pathway cAMP signaling pathway Cardiac muscle contraction +18 more

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